iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	44.83	5.40e+00	28.10	IUUC-Ots-000010

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). Involved in ribosome biosynthesis.

Protein Sequence
(Fasta)

MSSLSDQLAQ VASNNATVAL DRKRRQKLHS ASLIYNSKTA ATQDYDFIFE NASKALEELS 60
QIEPKFAIFS RTLFSESSIS LDRNVQTKEE IKDLDNAINA YLLLASSKWY LAPTLHATEW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTCGT TGAGTGACCA ATTAGCTCAA GTTGCTTCCA ACAATGCTAC TGTTGCGTTG 60
GATAGAAAGA GAAGACAAAA ACTTCATTCT GCTTCTTTGA TTTATAACTC AAAGACGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0496--Mitochondrion
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0804--Transcription

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR012954--BP28_C_dom
IPR021133--HEAT_type_2
IPR022125--U3snoRNP10

PROSITE

PS50077--HEAT_REPEAT

Pfam

PF08146--BP28CT
PF12397--U3snoRNP10

SMART

SM01036--BP28CT

Gene Ontology

GO:0030686--C:90S preribosome
GO:0005739--C:mitochondrion
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0030688--C:preribosome, small subunit precursor
GO:0033553--C:rDNA heterochromatin
GO:0032040--C:small-subunit processome
GO:0034455--C:t-UTP complex
GO:0030515--F:snoRNA binding
GO:0000480--P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472--P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0045943--P:positive regulation of transcription from RNA polymerase I promoter
GO:0031167--P:rRNA methylation
GO:0006351--P:transcription, DNA-templated

KEGG

sce:YJL109C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cin-025308	Ciona intestinalis	32.79	4.30e-01	27.30
IUUC-Mac-064841	Musa acuminata	25.36	1.80e-02	32.70
IUUC-Opr-070475	Ochotona princeps	37.14	5.80e-02	30.80
IUUC-Ont-072012	Oreochromis niloticus	29.03	2.80e+00	28.10
IUUC-Olo-080357	Oryza longistaminata	28.05	1.20e-01	29.30
IUUC-Pop-099287	Populus trichocarpa	27.27	4.80e-01	27.30
IUUC-Smo-109103	Selaginella moellendorffii	27.08	1.00e+00	29.60
IUUC-Stu-111924	Solanum tuberosum	36.07	1.00e-01	30.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence