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Tag Content
iUUCD ID IUUC-Sha-107099
Ensembl Protein ID ENSSHAP00000013713.1
UniProt Accession G3WE58; G3WE58_SARHA
Genbank Protein ID ENSSHAP00000013713
Protein Name Tyrosine-protein kinase
Genbank Nucleotide ID AEFK01019503
Gene Name HCK
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000011725.1 ENSSHAT00000013826.1 ENSSHAP00000013713.1
ENSSHAG00000011725.1 ENSSHAT00000013827.1 ENSSHAP00000013714.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 3.70e-16 59.0 96 151
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v +lydyea ++++L+++kGd++ ++   e++++W+k+ + ++ k+G +P+n+v++++
   Q: 96   TVVALYDYEAIHNEDLSFRKGDQMAIL---EKSGEWWKARSLATRKEGYIPSNYVAQIN 151
           799************************...**************************997 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
MPQERRRPQK TELATPRAGL EPHILGQFRR LKVRMGCVKS KFTHNGGKVF QKESETNTQG 60
PVYVPDPTSP GKKTDHGSGV SQVISSHADS ENMDITVVAL YDYEAIHNED LSFRKGDQMA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-107099|UBD,SH3|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAGAATGTTT TGTACAGAGT CGGAACTCCT GTGGGCGGGA CTAGGATCTT TTGGGTAGTT 60
GTCAGAACGC TAGTTTAAGG GTGCCTTTAG AATTGTTCCT GGACTAGTGA AAGTGTAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-107099|UBD,SH3|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE
SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001284 Ailuropoda melanoleuca 83.86 0.00e+00 890.00
IUUC-Apl-003285 Anas platyrhynchos 76.32 0.00e+00 799.00
IUUC-Aca-004724 Anolis carolinensis 75.49 0.00e+00 777.00
IUUC-Ame-011954 Astyanax mexicanus 73.19 0.00e+00 749.00
IUUC-Bta-013060 Bos taurus 84.25 0.00e+00 897.00
IUUC-Cja-019817 Callithrix jacchus 82.91 0.00e+00 878.00
IUUC-Cfa-020511 Canis familiaris 83.30 0.00e+00 887.00
IUUC-Cpo-022538 Cavia porcellus 80.74 0.00e+00 860.00
IUUC-Csa-024143 Chlorocebus sabaeus 82.33 0.00e+00 873.00
IUUC-Dre-028157 Danio rerio 74.46 0.00e+00 775.00
IUUC-Dno-029761 Dasypus novemcinctus 82.05 0.00e+00 869.00
IUUC-Eca-034090 Equus caballus 80.71 0.00e+00 848.00
IUUC-Fca-035937 Felis catus 81.82 0.00e+00 844.00
IUUC-Fal-036624 Ficedula albicollis 76.17 0.00e+00 801.00
IUUC-Gmo-039009 Gadus morhua 70.61 0.00e+00 739.00
IUUC-Gga-040296 Gallus gallus 73.91 0.00e+00 778.00
IUUC-Gac-042362 Gasterosteus aculeatus 72.10 0.00e+00 766.00
IUUC-Ggo-044570 Gorilla gorilla 82.71 0.00e+00 872.00
IUUC-Hsa-046378 Homo sapiens 83.01 0.00e+00 876.00
IUUC-Itr-048695 Ictidomys tridecemlineatus 82.71 0.00e+00 882.00
IUUC-Loc-052904 Lepisosteus oculatus 76.82 0.00e+00 816.00
IUUC-Laf-053654 Loxodonta africana 83.66 0.00e+00 883.00
IUUC-Mcc-055317 Macaca mulatta 82.85 0.00e+00 879.00
IUUC-Mga-060194 Meleagris gallopavo 79.19 0.00e+00 752.00
IUUC-Mmr-061510 Microcebus murinus 83.20 0.00e+00 880.00
IUUC-Mdo-062035 Monodelphis domestica 91.13 0.00e+00 1030.00
IUUC-Mmu-064037 Mus musculus 81.89 0.00e+00 878.00
IUUC-Mpu-066874 Mustela putorius furo 84.62 0.00e+00 897.00
IUUC-Mlu-068202 Myotis lucifugus 81.10 0.00e+00 858.00
IUUC-Nle-069222 Nomascus leucogenys 82.87 0.00e+00 874.00
IUUC-Opr-070705 Ochotona princeps 81.30 0.00e+00 866.00
IUUC-Ont-072347 Oreochromis niloticus 80.45 0.00e+00 749.00
IUUC-Ocu-074490 Oryctolagus cuniculus 79.88 0.00e+00 851.00
IUUC-Obr-076837 Oryza brachyantha 29.69 6.00e-21 95.90
IUUC-Olo-080886 Oryza longistaminata 30.55 4.00e-21 96.30
IUUC-Opu-083900 Oryza punctata 30.55 2.00e-21 97.80
IUUC-Ola-086521 Oryzias latipes 79.37 0.00e+00 759.00
IUUC-Oga-088153 Otolemur garnettii 82.68 0.00e+00 872.00
IUUC-Oar-090184 Ovis aries 83.95 0.00e+00 892.00
IUUC-Ptr-090505 Pan troglodytes 78.98 0.00e+00 820.00
IUUC-Pan-092260 Papio anubis 82.65 0.00e+00 877.00
IUUC-Pma-094311 Petromyzon marinus 69.33 0.00e+00 706.00
IUUC-Pfo-096566 Poecilia formosa 74.41 0.00e+00 785.00
IUUC-Pva-103021 Pteropus vampyrus 84.62 0.00e+00 894.00
IUUC-Rno-105309 Rattus norvegicus 82.05 0.00e+00 879.00
IUUC-Sbi-114009 Sorghum bicolor 31.48 1.00e-21 98.20
IUUC-Tgu-116912 Taeniopygia guttata 76.52 0.00e+00 793.00
IUUC-Tru-118449 Takifugu rubripes 80.00 0.00e+00 751.00
IUUC-Tbe-128144 Tupaia belangeri 81.03 0.00e+00 754.00
IUUC-Xma-133902 Xiphophorus maculatus 73.82 0.00e+00 780.00
Created Date 25-Jun-2017

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