iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047700

Ensembl Protein ID

MLOC_69164.1

UniProt Accession

M0YGP6; M0YGP6_HORVV

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_69164	MLOC_69164.1	MLOC_69164.1
MLOC_69164	MLOC_69164.2	MLOC_69164.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-93	315.2	814	1183

Active Site

Position(s)	Description	Evidence
1150	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvgEegldlgGvtreflallskelqnpdlglflysen...dketlqpnpdsglknp...............ehlklFeflGrllgka 81
            +k +ev fvgE g++  G+t ef++ +s+elq+  +g+++ ++n     e  +++++ gl ++               ++ k F++lG +++ a
   Q: 814  STKTIEVVFVGEVGTGR-GPTFEFYSTVSHELQRLGIGMWRGDNNarkAGEAGFVRSSFGLFPQpwssvgtstrgielsDVVKKFKLLGHVVARA 907
           56789************.**********************77766443222233333333333367777778*********************** PP
   S: 82   lqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaes.....................dieelgldltfsvseeilgetkeee 155
           l dgr+ld+plsk+fyk +lg++l++ d++++dpel k++ e ++++++                     ++  ++l+l f+     l+   ++e
   Q: 908  LLDGRILDIPLSKAFYKIMLGQELDIYDIPSFDPELGKTVLEFQALVKRkkflekssektpnrnadlsykNVRLEDLCLDFT-----LPGNPDYE 997
           ***************************************9999999833445555666677777777777888888888888.....99****** PP
   S: 156  LkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwF 249
           L+pgG++  Vt eN+eeYv+l+v+++lk+gi +qveaf++  nev+ l+ l++F+eee+e ++cGe +++ +++l++++++++gy ++sp i+ F
   Q: 998  LVPGGSEKIVTLENLEEYVNLIVDATLKSGIVKQVEAFKSAVNEVFALKTLRMFDEEEMERILCGEqDSWASSKLEDHIEFEHGYDASSPPIKSF 1092
           ******************************************************************999************************** PP
   S: 250  wevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk...dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
           +e+l+ef++e+++afLqF+Tg ++lPlgG+a+l p+l+v+rk    + d++lPs+nTC + +kLP+Ysskei+  kL yA  e+  +F+ls
   Q: 1093 LEILREFEREDQRAFLQFTTGAPQLPLGGLASLDPKLTVVRKqcdGNIDNELPSVNTCRHFIKLPPYSSKEIMLMKLKYALAEGlGSFHLS 1183
           *******************************************955556***********************************9***985 PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MALKIVTQLV QECDDADVPK AMEAAPALCN LLQSSDNSIL GSALSCLGML AADAHGKAEH 60
MDRLCESKVV DTAMGLLDKD GWKILDDDTL PGILALLKHI ASVSEKAVNS LFDLGVCDLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCCGGCCG GCAGTGCCTC CGAGCTCTGG ACGAGATATC CCAGGAATGC CCGGACGAGT 60
GCCTCCGCCT CGGCGTCGCC GCCGCCGCGC TGCACTTGTT CGACTTCCTC TCCGCCAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000538	Aegilops tauschii	91.06	0.00e+00	2141.00
IUUC-Aca-004521	Anolis carolinensis	38.83	4.00e-43	170.00
IUUC-Bdi-014726	Brachypodium distachyon	73.90	0.00e+00	1753.00
IUUC-Lpe-051372	Leersia perrieri	63.25	0.00e+00	1535.00
IUUC-Mga-059409	Meleagris gallopavo	39.52	8.00e-44	172.00
IUUC-Oba-075424	Oryza barthii	63.93	0.00e+00	1521.00
IUUC-Obr-076607	Oryza brachyantha	63.40	0.00e+00	1523.00
IUUC-Ogl-077414	Oryza glaberrima	63.93	0.00e+00	1521.00
IUUC-Ogu-078341	Oryza glumaepatula	64.09	0.00e+00	1523.00
IUUC-Oin-079282	Oryza indica	60.97	0.00e+00	1407.00
IUUC-Olo-080303	Oryza longistaminata	63.93	0.00e+00	1520.00
IUUC-Ome-081638	Oryza meridionalis	63.43	0.00e+00	1508.00
IUUC-Oni-082977	Oryza nivara	63.93	0.00e+00	1522.00
IUUC-Opu-083574	Oryza punctata	64.59	0.00e+00	1544.00
IUUC-Oru-084742	Oryza rufipogon	64.17	0.00e+00	1519.00
IUUC-Osa-085605	Oryza sativa	64.02	0.00e+00	1507.00
IUUC-Sit-110218	Setaria italica	63.58	0.00e+00	1502.00
IUUC-Sbi-114373	Sorghum bicolor	60.87	0.00e+00	1414.00
IUUC-Tgu-117167	Taeniopygia guttata	39.18	2.00e-43	170.00
IUUC-Tsy-119504	Tarsius syrichta	31.08	8.00e-52	199.00
IUUC-Tae-124019	Triticum aestivum	91.12	0.00e+00	2184.00
IUUC-Tur-126730	Triticum urartu	91.04	0.00e+00	2184.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence