iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cin-025114

Ensembl Protein ID

ENSCINP00000017456.3

UniProt Accession

F6XP43; F6XP43_CIOIN

Genbank Protein ID

ENSCINP00000017456

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

EAAA01002549

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000008550.3	ENSCINT00000017456.3	ENSCINP00000017456.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.00e-15	54.2	10	64

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
             ++ydy+a + ++L+++kG++++++ +++ +++W+++ + ++g++G +P+n+v+ 
   Q: 10   YVAMYDYDARTHEDLSFRKGETLFIL-NNNSEGDWWQARSAASGQEGYVPSNYVAP 64
           5689**********************.999************************86 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MQPAPGSLKY VAMYDYDART HEDLSFRKGE TLFILNNNSE GDWWQARSAA SGQEGYVPSN 60
YVAPAGGLDC EEWFFGKISR KECERKLIQH RTPRGTFMIR ESETAPGTYS LSITDQDQGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTAGGATA TAATAATAAA TAGTATTGTG ACATCACAAT ATGTTCCGTC GTTGTTTCGG 60
TTGCCTCTTC TGCAAGGGCA CCGACGACAC CCAACAAAAT GCCCCCGCCC AGGCCCCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005712	Arabidopsis lyrata	31.25	4.00e-17	82.00
IUUC-Ath-007146	Arabidopsis thaliana	31.96	2.00e-20	93.20
IUUC-Bdi-014324	Brachypodium distachyon	33.66	8.00e-22	97.80
IUUC-Bol-016049	Brassica oleracea	31.03	1.00e-16	80.90
IUUC-Csv-025950	Ciona savignyi	79.05	0.00e+00	701.00
IUUC-Gma-043938	Glycine max	33.50	9.00e-23	100.00
IUUC-Oba-075998	Oryza barthii	29.23	1.00e-20	93.60
IUUC-Ogl-077331	Oryza glaberrima	34.33	8.00e-24	104.00
IUUC-Ogu-078962	Oryza glumaepatula	34.33	9.00e-24	104.00
IUUC-Oin-079172	Oryza indica	34.33	8.00e-24	104.00
IUUC-Olo-080286	Oryza longistaminata	34.33	7.00e-24	104.00
IUUC-Ome-081400	Oryza meridionalis	34.33	7.00e-24	104.00
IUUC-Oni-082734	Oryza nivara	34.33	2.00e-23	103.00
IUUC-Opu-083538	Oryza punctata	33.83	3.00e-23	102.00
IUUC-Oru-084741	Oryza rufipogon	34.33	7.00e-24	104.00
IUUC-Osa-085779	Oryza sativa	34.33	8.00e-24	104.00
IUUC-Stu-112331	Solanum tuberosum	30.00	6.00e-22	97.80
IUUC-Sbi-114480	Sorghum bicolor	34.83	2.00e-22	100.00
IUUC-Tae-123414	Triticum aestivum	28.18	3.00e-19	89.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence