iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052803

Ensembl Protein ID

ENSLOCP00000011209.1

UniProt Accession

W5MS50; W5MS50_LEPOC

Genbank Protein ID

ENSLOCP00000011209

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01015457

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000009178.1	ENSLOCT00000011225.1	ENSLOCP00000011209.1
ENSLOCG00000009178.1	ENSLOCT00000011233.1	ENSLOCP00000011217.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.40e-97	326.0	755	1078

Active Site

Position(s)	Description	Evidence
1047	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           dlkk l+v f gEe++d+gGvt+ef+ ll+kel +p +g+f++ e+++  ++ ++        +l++F+++G+ +g+a++++ ++dl
   Q: 755  DLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLDPVYGMFTHYEESNLLWFSDKCFV-----ELNWFHLIGITCGLAIYNSTVVDL 836
           899******************************************9999999887664.....7*********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           +++ ++yk+ll+++ sledl+e+ p+  +sl+++++++ +d+ee+ ++l+f ++ e++g t+++eL+++Geni V+++N+ee+v+++
   Q: 837  HFPLALYKKLLDVPPSLEDLKELSPTEGRSLQQLLDYQGDDVEES-FCLNFAITRENYGLTEVKELVQEGENITVNKDNREEFVQAY 922
           *************************************98888887.***************************************** PP
   S: 178  veyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           ++y +++++ke ++af++Gf +v+  ++lslF+++el  ++ G++++++e+++k++ ykg+y++++p++++Fwev++ef  e++k+f
   Q: 923  LNYVFNDSVKELYTAFSSGFLKVCGGKVLSLFQPSELMAMVVGNNNYNWEEMEKNAVYKGEYSATHPTVKMFWEVFHEFPLEKKKQF 1009
           *************************************************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           L F+Tgs+r+P+ G+++l+   +vi+  +a+++ lP ++TC+n+L++P+Y++keil+++L+ Aie+ +gF+l
   Q: 1010 LLFLTGSDRIPIYGMESLR---VVIQStSAEEHYLPVAHTCYNLLDMPRYKTKEILRKRLTQAIEQYEGFSL 1078
           *******************...8888867888**************************************97 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MMLCWGNTAA GQLGLGDLET TVYEPRSCKV FSSRGLKEIA CGGQHSVFLL HDGSLYSCGS 60
NSWGQLGHEK GGGRPELVGA LDAQKIAAVC CGEAHSLAVN EQGQVFSWGA GNEGQLGLGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTCTCATT TGTTTCAAGG ACAGTGGAGA GAGGCTCCTT GCCTAGTGCA TTCCTGAAGC 60
ATGATGCTGT GCTGGGGCAA CACGGCTGCA GGCCAGCTTG GCCTAGGTGA CTTGGAAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001673	Ailuropoda melanoleuca	67.25	0.00e+00	1438.00
IUUC-Apl-003535	Anas platyrhynchos	67.81	0.00e+00	1449.00
IUUC-Aca-005223	Anolis carolinensis	67.56	0.00e+00	1434.00
IUUC-Ame-010816	Astyanax mexicanus	79.39	0.00e+00	1454.00
IUUC-Bta-013373	Bos taurus	67.16	0.00e+00	1444.00
IUUC-Bdi-014791	Brachypodium distachyon	40.26	9.00e-55	207.00
IUUC-Cel-018150	Caenorhabditis elegans	33.27	4.00e-151	528.00
IUUC-Cja-019609	Callithrix jacchus	67.25	0.00e+00	1434.00
IUUC-Cfa-021071	Canis familiaris	67.25	0.00e+00	1435.00
IUUC-Cpo-021548	Cavia porcellus	67.16	0.00e+00	1431.00
IUUC-Csa-023987	Chlorocebus sabaeus	67.53	0.00e+00	1441.00
IUUC-Cho-024325	Choloepus hoffmanni	74.96	0.00e+00	915.00
IUUC-Dre-027472	Danio rerio	78.68	0.00e+00	1748.00
IUUC-Dno-029241	Dasypus novemcinctus	66.57	0.00e+00	1419.00
IUUC-Dor-030672	Dipodomys ordii	55.41	0.00e+00	689.00
IUUC-Ete-032642	Echinops telfairi	64.60	0.00e+00	1327.00
IUUC-Eca-033646	Equus caballus	67.25	0.00e+00	1436.00
IUUC-Eeu-035098	Erinaceus europaeus	65.65	0.00e+00	889.00
IUUC-Fal-036952	Ficedula albicollis	67.90	0.00e+00	1449.00
IUUC-Gmo-039297	Gadus morhua	75.90	0.00e+00	1618.00
IUUC-Gga-040591	Gallus gallus	67.47	0.00e+00	1436.00
IUUC-Gac-041741	Gasterosteus aculeatus	75.97	0.00e+00	1675.00
IUUC-Gma-043616	Glycine max	38.76	4.00e-53	202.00
IUUC-Ggo-044769	Gorilla gorilla	67.38	0.00e+00	1434.00
IUUC-Hsa-046066	Homo sapiens	67.44	0.00e+00	1439.00
IUUC-Itr-048311	Ictidomys tridecemlineatus	67.47	0.00e+00	1438.00
IUUC-Lch-050301	Latimeria chalumnae	68.91	0.00e+00	1529.00
IUUC-Laf-053364	Loxodonta africana	67.16	0.00e+00	1430.00
IUUC-Mcc-054930	Macaca mulatta	67.44	0.00e+00	1440.00
IUUC-Meu-056274	Macropus eugenii	52.79	9.00e-165	574.00
IUUC-Mtr-058277	Medicago truncatula	37.13	5.00e-53	201.00
IUUC-Mga-059563	Meleagris gallopavo	67.63	0.00e+00	1447.00
IUUC-Mmr-060792	Microcebus murinus	66.51	0.00e+00	1408.00
IUUC-Mdo-062195	Monodelphis domestica	67.38	0.00e+00	1438.00
IUUC-Mmu-063855	Mus musculus	66.23	0.00e+00	1425.00
IUUC-Mpu-066308	Mustela putorius furo	67.35	0.00e+00	1439.00
IUUC-Mlu-066927	Myotis lucifugus	67.44	0.00e+00	1444.00
IUUC-Nle-070090	Nomascus leucogenys	67.53	0.00e+00	1441.00
IUUC-Opr-070891	Ochotona princeps	59.37	0.00e+00	1216.00
IUUC-Ont-072201	Oreochromis niloticus	74.20	0.00e+00	1635.00
IUUC-Ocu-074770	Oryctolagus cuniculus	67.53	0.00e+00	1437.00
IUUC-Olo-080768	Oryza longistaminata	40.13	7.00e-56	211.00
IUUC-Ola-086550	Oryzias latipes	74.70	0.00e+00	1651.00
IUUC-Oga-088831	Otolemur garnettii	67.44	0.00e+00	1434.00
IUUC-Oar-090449	Ovis aries	67.07	0.00e+00	1437.00
IUUC-Pan-092135	Papio anubis	67.81	0.00e+00	1441.00
IUUC-Psi-093832	Pelodiscus sinensis	66.45	0.00e+00	1448.00
IUUC-Pfo-097268	Poecilia formosa	75.14	0.00e+00	1660.00
IUUC-Pab-098249	Pongo abelii	67.35	0.00e+00	1437.00
IUUC-Pca-100855	Procavia capensis	59.79	0.00e+00	915.00
IUUC-Pva-102506	Pteropus vampyrus	61.17	0.00e+00	1235.00
IUUC-Rno-105242	Rattus norvegicus	66.60	0.00e+00	1469.00
IUUC-Sit-110415	Setaria italica	39.54	1.00e-56	213.00
IUUC-Sar-113612	Sorex araneus	75.90	3.00e-166	579.00
IUUC-Ssc-115473	Sus scrofa	67.07	0.00e+00	1433.00
IUUC-Tgu-116974	Taeniopygia guttata	67.66	0.00e+00	1427.00
IUUC-Tru-118077	Takifugu rubripes	74.08	0.00e+00	1591.00
IUUC-Tsy-119619	Tarsius syrichta	57.65	0.00e+00	1225.00
IUUC-Tni-120807	Tetraodon nigroviridis	74.38	0.00e+00	1608.00
IUUC-Tbe-127640	Tupaia belangeri	65.03	0.00e+00	1349.00
IUUC-Ttr-129172	Tursiops truncatus	66.70	0.00e+00	1420.00
IUUC-Xtr-132194	Xenopus tropicalis	60.11	0.00e+00	1193.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence