iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000000456.1	ENSOART00000000493.1	ENSOARP00000000465.1
ENSOARG00000000456.1	ENSOART00000000496.1	ENSOARP00000000468.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.20e-13	48.1	459	508

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 459  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--LCKGRYGLFPANYVE 508
           79***********************..9*********..9************97 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

FQNDVSEKEQ RWGAKTVQGS GHQEHINIHK LRENVFQEHQ TLKEKELETG PKASHGYGGK 60
FGVEQDRMDK SAVGHEYQSK LSKHCSQVDS VRGFGGKFGV QVDRVDQSAV GFEYQGKTEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTTTGGGG TCCTGGGCAG AGCGTCTGTG GGCCCCTGGG CAGGGCTCTG CTGGCGGCTG 60
TGACCCTCAG CGCTGCCCTT CCAGATGTGG CCCGTCTCCT GAAGTGGATC CTCCCGGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	88.78	0.00e+00	837.00
IUUC-Apl-003745	Anas platyrhynchos	82.35	0.00e+00	709.00
IUUC-Aca-004438	Anolis carolinensis	78.28	0.00e+00	787.00
IUUC-Ame-011170	Astyanax mexicanus	46.60	8.00e-108	384.00
IUUC-Bgr-012041	Blumeria graminis	57.89	8.00e-16	79.00
IUUC-Bta-013563	Bos taurus	97.46	0.00e+00	895.00
IUUC-Bci-013690	Botrytis cinerea	58.82	4.00e-12	67.00
IUUC-Cel-018639	Caenorhabditis elegans	40.46	7.00e-19	89.00
IUUC-Cfa-020718	Canis familiaris	85.55	0.00e+00	833.00
IUUC-Cpo-022303	Cavia porcellus	85.85	0.00e+00	883.00
IUUC-Csa-023431	Chlorocebus sabaeus	88.34	0.00e+00	828.00
IUUC-Cin-025677	Ciona intestinalis	60.73	3.00e-116	412.00
IUUC-Csv-026140	Ciona savignyi	63.67	1.00e-106	380.00
IUUC-Dre-028012	Danio rerio	63.60	1.00e-164	573.00
IUUC-Dno-029332	Dasypus novemcinctus	79.35	0.00e+00	691.00
IUUC-Eca-033801	Equus caballus	90.79	0.00e+00	837.00
IUUC-Fca-035633	Felis catus	86.79	0.00e+00	730.00
IUUC-Fal-036775	Ficedula albicollis	81.97	0.00e+00	706.00
IUUC-Fox-037778	Fusarium oxysporum	59.65	1.00e-14	75.50
IUUC-Gmo-038507	Gadus morhua	61.97	2.00e-21	97.10
IUUC-Gga-040568	Gallus gallus	82.73	0.00e+00	740.00
IUUC-Gac-042253	Gasterosteus aculeatus	56.01	8.00e-106	377.00
IUUC-Hsa-046818	Homo sapiens	88.72	0.00e+00	831.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	85.63	0.00e+00	774.00
IUUC-Lch-050199	Latimeria chalumnae	69.07	3.00e-128	452.00
IUUC-Loc-052855	Lepisosteus oculatus	74.85	9.00e-139	486.00
IUUC-Lma-053035	Leptosphaeria maculans	59.18	2.00e-12	67.80
IUUC-Laf-053866	Loxodonta africana	87.57	0.00e+00	890.00
IUUC-Mcc-055515	Macaca mulatta	88.72	0.00e+00	830.00
IUUC-Mpo-057325	Magnaporthe poae	50.98	2.00e-10	58.20
IUUC-Mga-059791	Meleagris gallopavo	78.74	0.00e+00	735.00
IUUC-Mmr-061147	Microcebus murinus	88.00	0.00e+00	778.00
IUUC-Mdo-062660	Monodelphis domestica	59.36	5.00e-157	548.00
IUUC-Mmu-064023	Mus musculus	88.05	0.00e+00	824.00
IUUC-Mpu-065867	Mustela putorius furo	79.69	0.00e+00	721.00
IUUC-Mlu-067704	Myotis lucifugus	82.95	0.00e+00	711.00
IUUC-Ont-071873	Oreochromis niloticus	79.70	7.00e-156	543.00
IUUC-Oan-073528	Ornithorhynchus anatinus	79.55	6.00e-156	543.00
IUUC-Oga-088028	Otolemur garnettii	87.76	0.00e+00	818.00
IUUC-Pan-092594	Papio anubis	84.35	0.00e+00	773.00
IUUC-Psi-093389	Pelodiscus sinensis	81.41	0.00e+00	742.00
IUUC-Pma-094161	Petromyzon marinus	45.10	3.00e-73	269.00
IUUC-Pfo-097391	Poecilia formosa	55.12	1.00e-102	367.00
IUUC-Pab-097913	Pongo abelii	81.07	0.00e+00	723.00
IUUC-Rno-105489	Rattus norvegicus	87.86	0.00e+00	802.00
IUUC-Sha-107308	Sarcophilus harrisii	69.11	2.00e-172	598.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	2.00e-14	74.30
IUUC-Tgu-117049	Taeniopygia guttata	75.96	0.00e+00	644.00
IUUC-Tru-118718	Takifugu rubripes	76.20	1.00e-145	509.00
IUUC-Tni-120535	Tetraodon nigroviridis	53.09	6.00e-140	490.00
IUUC-Vda-129766	Verticillium dahliae	57.89	1.00e-13	72.00
IUUC-Xtr-131797	Xenopus tropicalis	75.83	2.00e-148	519.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence