iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	PINA
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-08	34.8	253	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++df  ++ ++ lpC H++h++C+  w       + + +CP+Cr
   Q: 253  CSICWDDFkiDETVRKLPCSHLYHENCIVPW------LNLHSTCPICR 294
           ********99666******************......**********8 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MAEAMVVEDR PAEAKRFFCH MCNVEINIPN SDFTCPLCAN GFVEELPANA PEMDSSTAGA 60
SGSARSGSSG SGSSGSHDTL SRGSSSSGSQ VNVESLRNDI VSLLNMRNVP NLEITIEPNR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTTGGGAT TTATTCTCCT CTGCGGCAAA GGCCACTTTG TAAGGGGCCC TTATTTATAG 60
AAAAATTAAA TTCTATCCCT TAAACTCCCA ATTGTTCCGA CTGAACCCAA TGACCGGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

dme:Dmel_CG11982

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000551	Aegilops tauschii	40.62	4.00e-20	90.90
IUUC-Aml-002035	Ailuropoda melanoleuca	52.83	4.00e-35	140.00
IUUC-Atr-002984	Amborella trichopoda	39.05	1.00e-19	89.40
IUUC-Apl-003694	Anas platyrhynchos	52.25	6.00e-36	143.00
IUUC-Aca-005166	Anolis carolinensis	51.16	6.00e-27	113.00
IUUC-Aly-006394	Arabidopsis lyrata	33.33	5.00e-21	94.40
IUUC-Ath-006991	Arabidopsis thaliana	36.04	5.00e-21	94.40
IUUC-Ago-007829	Ashbya gossypii	33.33	1.00e-07	49.70
IUUC-Acl-008247	Aspergillus clavatus	34.00	4.00e-16	78.60
IUUC-Afl-008423	Aspergillus flavus	36.00	4.00e-17	82.00
IUUC-Afu-008920	Aspergillus fumigatus	33.00	9.00e-15	73.90
IUUC-Ani-009396	Aspergillus nidulans	34.34	2.00e-15	75.90
IUUC-Ang-009638	Aspergillus niger	36.46	5.00e-14	71.20
IUUC-Aor-009896	Aspergillus oryzae	36.00	3.00e-17	82.00
IUUC-Ate-010398	Aspergillus terreus	35.00	2.00e-16	79.30
IUUC-Ame-010626	Astyanax mexicanus	52.34	6.00e-34	137.00
IUUC-Bgr-012144	Blumeria graminis	39.81	1.00e-18	86.70
IUUC-Bta-013190	Bos taurus	50.46	5.00e-35	140.00
IUUC-Bci-013958	Botrytis cinerea	38.83	4.00e-18	85.50
IUUC-Bdi-014137	Brachypodium distachyon	39.42	2.00e-20	91.70
IUUC-Bol-016085	Brassica oleracea	36.94	1.00e-21	96.70
IUUC-Bra-016935	Brassica rapa	39.80	6.00e-22	97.40
IUUC-Cel-018216	Caenorhabditis elegans	39.34	5.00e-13	67.40
IUUC-Cja-020001	Callithrix jacchus	51.52	3.00e-33	134.00
IUUC-Cfa-020882	Canis familiaris	52.83	5.00e-35	140.00
IUUC-Cpo-021690	Cavia porcellus	53.54	1.00e-34	139.00
IUUC-Csa-024004	Chlorocebus sabaeus	54.55	2.00e-35	141.00
IUUC-Cho-024643	Choloepus hoffmanni	52.83	8.00e-35	139.00
IUUC-Cin-025452	Ciona intestinalis	42.17	4.00e-18	82.80
IUUC-Csv-025892	Ciona savignyi	44.32	1.00e-20	91.30
IUUC-Cgl-026759	Colletotrichum gloeosporioides	31.37	2.00e-15	76.30
IUUC-Cne-026837	Cryptococcus neoformans	34.86	3.00e-15	75.90
IUUC-Dre-027678	Danio rerio	54.29	4.00e-35	140.00
IUUC-Dno-029010	Dasypus novemcinctus	53.54	1.00e-34	139.00
IUUC-Dor-030147	Dipodomys ordii	56.57	4.00e-36	144.00
IUUC-Dse-031376	Dothistroma septosporum	39.25	3.00e-19	89.40
IUUC-Ete-032392	Echinops telfairi	50.47	5.00e-33	134.00
IUUC-Eca-033803	Equus caballus	54.55	3.00e-35	140.00
IUUC-Eeu-034831	Erinaceus europaeus	36.36	3.00e-11	61.60
IUUC-Fca-036192	Felis catus	52.83	2.00e-35	141.00
IUUC-Fal-037027	Ficedula albicollis	54.00	1.00e-34	139.00
IUUC-Fox-038011	Fusarium oxysporum	40.24	8.00e-13	67.80
IUUC-Fso-038447	Fusarium solani	34.00	1.00e-15	77.00
IUUC-Gmo-038515	Gadus morhua	49.55	3.00e-34	137.00
IUUC-Gga-040282	Gallus gallus	43.97	1.00e-35	141.00
IUUC-Gac-041364	Gasterosteus aculeatus	51.40	2.00e-33	135.00
IUUC-Gma-043643	Glycine max	40.38	4.00e-21	94.70
IUUC-Ggo-044873	Gorilla gorilla	54.55	2.00e-35	141.00
IUUC-Hsa-045780	Homo sapiens	54.55	2.00e-35	141.00
IUUC-Hvu-047295	Hordeum vulgare	46.43	3.00e-15	75.10
IUUC-Itr-048142	Ictidomys tridecemlineatus	54.55	2.00e-35	141.00
IUUC-Lch-050071	Latimeria chalumnae	53.92	1.00e-34	139.00
IUUC-Lpe-050861	Leersia perrieri	35.81	5.00e-19	87.40
IUUC-Loc-052470	Lepisosteus oculatus	50.57	4.00e-26	110.00
IUUC-Lma-053066	Leptosphaeria maculans	36.70	9.00e-19	87.80
IUUC-Laf-054384	Loxodonta africana	50.94	3.00e-33	134.00
IUUC-Mcc-055137	Macaca mulatta	54.55	2.00e-35	141.00
IUUC-Meu-056635	Macropus eugenii	54.55	5.00e-35	140.00
IUUC-Mtr-057711	Medicago truncatula	34.25	8.00e-22	96.30
IUUC-Mla-058832	Melampsora laricipopulina	40.54	2.00e-14	70.90
IUUC-Mga-059349	Meleagris gallopavo	55.00	6.00e-34	137.00
IUUC-Mvi-060434	Microbotryum violaceum	32.69	5.00e-15	74.70
IUUC-Mmr-060631	Microcebus murinus	54.55	4.00e-35	140.00
IUUC-Mdo-062489	Monodelphis domestica	52.83	1.00e-34	139.00
IUUC-Mmu-064196	Mus musculus	55.56	8.00e-36	143.00
IUUC-Mac-064627	Musa acuminata	35.90	1.00e-20	92.80
IUUC-Mpu-066575	Mustela putorius furo	52.83	3.00e-35	141.00
IUUC-Mlu-067024	Myotis lucifugus	55.56	1.00e-34	139.00
IUUC-Nfi-068352	Neosartorya fischeri	34.00	6.00e-15	74.70
IUUC-Ncr-068908	Neurospora crassa	33.01	8.00e-16	77.80
IUUC-Nle-069348	Nomascus leucogenys	54.55	3.00e-35	141.00
IUUC-Opr-070812	Ochotona princeps	52.83	2.00e-34	139.00
IUUC-Ont-072238	Oreochromis niloticus	49.56	3.00e-35	140.00
IUUC-Oan-073225	Ornithorhynchus anatinus	55.00	9.00e-35	139.00
IUUC-Ocu-074691	Oryctolagus cuniculus	54.55	1.00e-34	139.00
IUUC-Oba-075906	Oryza barthii	34.48	3.00e-18	84.70
IUUC-Obr-076829	Oryza brachyantha	41.41	1.00e-20	92.40
IUUC-Ogl-077711	Oryza glaberrima	34.48	3.00e-18	84.70
IUUC-Ogu-078438	Oryza glumaepatula	34.48	3.00e-18	84.70
IUUC-Oin-079400	Oryza indica	41.76	2.00e-20	92.00
IUUC-Olo-080762	Oryza longistaminata	41.41	1.00e-20	92.40
IUUC-Ome-081151	Oryza meridionalis	40.40	4.00e-20	91.30
IUUC-Oni-082551	Oryza nivara	41.76	2.00e-20	92.00
IUUC-Opu-083961	Oryza punctata	33.09	2.00e-19	89.00
IUUC-Oru-084420	Oryza rufipogon	34.48	3.00e-18	84.70
IUUC-Osa-085753	Oryza sativa	34.48	3.00e-18	84.70
IUUC-Ola-087338	Oryzias latipes	51.38	2.00e-34	139.00
IUUC-Olu-087770	Ostreococcus lucimarinus	46.94	3.00e-11	58.90
IUUC-Oga-089111	Otolemur garnettii	52.83	7.00e-35	140.00
IUUC-Oar-089999	Ovis aries	50.46	8.00e-35	140.00
IUUC-Ptr-091473	Pan troglodytes	54.55	3.00e-35	141.00
IUUC-Pan-092618	Papio anubis	54.55	3.00e-35	140.00
IUUC-Psi-093930	Pelodiscus sinensis	52.83	9.00e-35	139.00
IUUC-Pma-094408	Petromyzon marinus	49.02	2.00e-31	129.00
IUUC-Pno-094903	Phaeosphaeria nodorum	41.35	7.00e-19	87.80
IUUC-Ppa-095873	Physcomitrella patens	40.00	8.00e-22	97.40
IUUC-Pfo-097402	Poecilia formosa	52.68	4.00e-35	140.00
IUUC-Pab-098466	Pongo abelii	54.55	2.00e-35	141.00
IUUC-Pop-099779	Populus trichocarpa	38.39	7.00e-22	96.70
IUUC-Pca-100442	Procavia capensis	52.53	9.00e-33	132.00
IUUC-Ppe-101439	Prunus persica	39.22	8.00e-20	90.50
IUUC-Pva-102881	Pteropus vampyrus	54.72	2.00e-35	142.00
IUUC-Pgr-103273	Puccinia graminis	34.55	2.00e-15	75.50
IUUC-Ptt-103768	Puccinia triticina	31.48	5.00e-13	68.60
IUUC-Pte-104223	Pyrenophora teres	34.76	3.00e-21	96.30
IUUC-Pyt-104653	Pyrenophora triticirepentis	40.17	2.00e-20	92.80
IUUC-Rno-104914	Rattus norvegicus	55.56	7.00e-36	143.00
IUUC-Sha-107616	Sarcophilus harrisii	52.83	5.00e-35	140.00
IUUC-Sja-107922	Schizosaccharomyces japonicus	38.83	1.00e-23	103.00
IUUC-Spo-108354	Schizosaccharomyces pombe	42.57	1.00e-22	100.00
IUUC-Ssl-108600	Sclerotinia sclerotiorum	32.00	3.00e-12	66.20
IUUC-Smo-109456	Selaginella moellendorffii	35.96	3.00e-20	92.40
IUUC-Sit-110071	Setaria italica	26.82	9.00e-23	99.80
IUUC-Sly-111262	Solanum lycopersicum	37.84	2.00e-19	88.60
IUUC-Stu-112432	Solanum tuberosum	35.45	1.00e-20	93.60
IUUC-Sar-113319	Sorex araneus	35.46	2.00e-22	98.60
IUUC-Sbi-113983	Sorghum bicolor	34.46	4.00e-21	94.40
IUUC-Sre-115230	Sporisorium reilianum	34.17	8.00e-18	84.70
IUUC-Ssc-115917	Sus scrofa	51.38	2.00e-35	142.00
IUUC-Tgu-117105	Taeniopygia guttata	50.00	5.00e-35	138.00
IUUC-Tru-117681	Takifugu rubripes	51.40	2.00e-34	138.00
IUUC-Tsy-119630	Tarsius syrichta	49.54	7.00e-33	133.00
IUUC-Tni-120720	Tetraodon nigroviridis	55.56	2.00e-34	139.00
IUUC-Tca-121480	Theobroma cacao	38.32	2.00e-21	95.10
IUUC-Tre-122013	Trichoderma reesei	35.19	2.00e-17	82.80
IUUC-Tvi-122598	Trichoderma virens	35.35	2.00e-17	83.60
IUUC-Tae-124604	Triticum aestivum	46.43	2.00e-15	75.50
IUUC-Tur-126272	Triticum urartu	38.78	9.00e-18	84.00
IUUC-Tme-127143	Tuber melanosporum	38.14	2.00e-20	92.00
IUUC-Tbe-127794	Tupaia belangeri	42.42	1.00e-22	99.00
IUUC-Ttr-128843	Tursiops truncatus	49.53	5.00e-33	134.00
IUUC-Uma-129414	Ustilago maydis	31.67	5.00e-16	78.60
IUUC-Vda-129671	Verticillium dahliae	34.29	7.00e-15	75.10
IUUC-Vpa-130755	Vicugna pacos	52.83	4.00e-35	140.00
IUUC-Vvi-130992	Vitis vinifera	32.43	4.00e-21	94.70
IUUC-Xtr-132520	Xenopus tropicalis	53.77	3.00e-34	137.00
IUUC-Xma-133481	Xiphophorus maculatus	52.68	4.00e-35	140.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence