iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.70e-06	28.9	7	50

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC + f   +d +    CgH+fh++Cl +w     ++ ++ +CP Cr
   Q: 7    CTICSDFFdhsRD-VAAIHCGHTFHLQCLIQW----FETAPSRTCPQCR 50
           9***776655344.88999*************....9***********8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MPIRALCTIC SDFFDHSRDV AAIHCGHTFH LQCLIQWFET APSRTCPQCR IQVGKKTIIN 60
KLFFDLAQEE ESVLDAEFLK NELDSIKAQL SQKDREKRDS QAIIDTLRDT LEERNATVES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGCGCCCC GCCCCGAAGT TTGTCCAATC AGGGGGGAGC AGTCAGAAGT GGGTTTGTTA 60
TGACTTCCGG TTCACTGCCG GAAGTCGTGC GGTGGAGCGA AATTTGAAGG AGTGGGAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005057--F:signal transducer activity, downstream of receptor
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032688--P:negative regulation of interferon-beta production
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway

KEGG

rno:367167

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001411	Ailuropoda melanoleuca	77.27	0.00e+00	691.00
IUUC-Atr-002646	Amborella trichopoda	30.65	1.00e-07	51.60
IUUC-Apl-003777	Anas platyrhynchos	57.53	1.00e-111	396.00
IUUC-Aca-004476	Anolis carolinensis	55.84	5.00e-144	504.00
IUUC-Ame-011706	Astyanax mexicanus	44.00	2.00e-08	49.70
IUUC-Bta-013084	Bos taurus	76.48	0.00e+00	700.00
IUUC-Cel-018227	Caenorhabditis elegans	25.72	2.00e-12	67.00
IUUC-Cja-019856	Callithrix jacchus	82.05	0.00e+00	747.00
IUUC-Cfa-020075	Canis familiaris	80.34	0.00e+00	758.00
IUUC-Cpo-022481	Cavia porcellus	78.25	0.00e+00	736.00
IUUC-Csa-023793	Chlorocebus sabaeus	80.98	0.00e+00	767.00
IUUC-Csv-026190	Ciona savignyi	34.30	7.00e-42	164.00
IUUC-Dre-027984	Danio rerio	49.17	5.00e-123	434.00
IUUC-Dno-029478	Dasypus novemcinctus	79.06	0.00e+00	739.00
IUUC-Dor-030526	Dipodomys ordii	59.02	2.00e-153	535.00
IUUC-Dme-032130	Drosophila melanogaster	30.88	8.00e-21	94.70
IUUC-Ete-033012	Echinops telfairi	86.05	6.00e-143	500.00
IUUC-Eca-034084	Equus caballus	81.49	0.00e+00	774.00
IUUC-Eeu-034579	Erinaceus europaeus	72.56	3.00e-170	591.00
IUUC-Fca-035772	Felis catus	82.05	0.00e+00	755.00
IUUC-Fal-037098	Ficedula albicollis	57.98	1.00e-137	483.00
IUUC-Gmo-038704	Gadus morhua	48.19	5.00e-114	404.00
IUUC-Gga-041109	Gallus gallus	53.54	3.00e-139	488.00
IUUC-Gac-042636	Gasterosteus aculeatus	46.84	8.00e-120	423.00
IUUC-Ggo-045184	Gorilla gorilla	81.62	0.00e+00	773.00
IUUC-Hsa-046651	Homo sapiens	81.41	0.00e+00	741.00
IUUC-Itr-048550	Ictidomys tridecemlineatus	81.06	0.00e+00	785.00
IUUC-Lch-049575	Latimeria chalumnae	55.30	1.00e-134	473.00
IUUC-Lpe-051238	Leersia perrieri	34.78	8.00e-06	45.40
IUUC-Loc-051999	Lepisosteus oculatus	51.48	9.00e-125	440.00
IUUC-Lma-053133	Leptosphaeria maculans	42.11	6.00e-08	51.20
IUUC-Laf-053347	Loxodonta africana	80.00	0.00e+00	760.00
IUUC-Mcc-054668	Macaca mulatta	71.07	2.00e-74	271.00
IUUC-Meu-056862	Macropus eugenii	60.47	4.00e-157	547.00
IUUC-Mga-059443	Meleagris gallopavo	54.85	6.00e-116	410.00
IUUC-Mmr-061219	Microcebus murinus	79.06	0.00e+00	740.00
IUUC-Mdo-062103	Monodelphis domestica	68.14	0.00e+00	640.00
IUUC-Mmu-064005	Mus musculus	91.49	0.00e+00	878.00
IUUC-Mpu-066570	Mustela putorius furo	79.70	0.00e+00	733.00
IUUC-Mlu-067806	Myotis lucifugus	80.21	0.00e+00	739.00
IUUC-Nle-069123	Nomascus leucogenys	81.84	0.00e+00	769.00
IUUC-Opr-071063	Ochotona princeps	79.57	0.00e+00	759.00
IUUC-Ont-071973	Oreochromis niloticus	48.83	4.00e-123	434.00
IUUC-Oan-073278	Ornithorhynchus anatinus	64.81	3.00e-92	331.00
IUUC-Ocu-074582	Oryctolagus cuniculus	74.84	0.00e+00	692.00
IUUC-Ogl-077006	Oryza glaberrima	36.23	3.00e-06	47.00
IUUC-Oin-079866	Oryza indica	24.50	2.00e-07	50.80
IUUC-Olo-081029	Oryza longistaminata	36.23	3.00e-06	47.00
IUUC-Osa-085981	Oryza sativa	24.50	2.00e-07	50.80
IUUC-Ola-086959	Oryzias latipes	47.00	1.00e-113	403.00
IUUC-Oga-088807	Otolemur garnettii	78.94	0.00e+00	724.00
IUUC-Oar-089273	Ovis aries	73.67	0.00e+00	677.00
IUUC-Ptr-090768	Pan troglodytes	81.84	0.00e+00	776.00
IUUC-Pan-091880	Papio anubis	80.98	0.00e+00	764.00
IUUC-Psi-093782	Pelodiscus sinensis	61.59	5.00e-138	484.00
IUUC-Pma-094365	Petromyzon marinus	36.82	1.00e-62	233.00
IUUC-Ppa-095896	Physcomitrella patens	35.21	7.00e-06	45.80
IUUC-Pfo-096068	Poecilia formosa	48.36	3.00e-113	401.00
IUUC-Pab-098063	Pongo abelii	79.53	0.00e+00	740.00
IUUC-Pca-100327	Procavia capensis	82.42	9.00e-167	579.00
IUUC-Pva-102924	Pteropus vampyrus	79.91	0.00e+00	728.00
IUUC-Pgr-103587	Puccinia graminis	42.86	3.00e-06	46.20
IUUC-Ptt-103972	Puccinia triticina	28.40	5.00e-07	49.30
IUUC-Pte-104366	Pyrenophora teres	30.40	3.00e-08	52.40
IUUC-Sha-107643	Sarcophilus harrisii	62.59	6.00e-152	530.00
IUUC-Sit-109687	Setaria italica	36.23	7.00e-07	48.90
IUUC-Sar-113187	Sorex araneus	73.62	0.00e+00	630.00
IUUC-Sbi-114760	Sorghum bicolor	36.23	7.00e-07	48.90
IUUC-Sre-115057	Sporisorium reilianum	35.71	5.00e-06	46.20
IUUC-Ssc-115838	Sus scrofa	89.39	1.00e-138	485.00
IUUC-Tgu-116674	Taeniopygia guttata	56.44	1.00e-127	449.00
IUUC-Tru-117753	Takifugu rubripes	44.80	1.00e-112	400.00
IUUC-Tsy-119416	Tarsius syrichta	67.05	4.00e-59	221.00
IUUC-Tni-120767	Tetraodon nigroviridis	47.89	1.00e-111	396.00
IUUC-Tbe-128001	Tupaia belangeri	46.48	4.00e-73	268.00
IUUC-Ttr-128687	Tursiops truncatus	80.85	0.00e+00	762.00
IUUC-Xtr-131905	Xenopus tropicalis	52.68	1.00e-140	493.00
IUUC-Xma-133304	Xiphophorus maculatus	48.93	1.00e-114	406.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence