iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074301

Ensembl Protein ID

ENSOCUP00000001474.3

UniProt Accession

G1SFZ8; G1SFZ8_RABIT

Protein Name

Uncharacterized protein

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000001718.3	ENSOCUT00000001718.3	ENSOCUP00000001474.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	2.00e-08	34.2	530	564
ULD/UDP/UBQ/UBQ_PIM	3.70e-25	87.7	22	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAve 36
           ++++leql +MGF +re++lqaL a++++++aA+e
   Q: 530  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIE 564
           799*******************************8 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksks 76
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++s
   Q: 22   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNS 96
           99**********.***********************************************************9975 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAESGESGGP AGSQDSAEPK IMKVTVKTPK EKEEFAVPEN SSVQQFKEEI SKRFKSHTDQ 60
LVLIFAGKIL KDQDTLSQHG IHDGLTVHLV IKTQNSLQDL RRENTLTDFP NSLTSSESSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGA GTGGTGAAAG CGGCGGCCCT GCGGGCTCGC AGGACGGCGC CGCCGCGGCC 60
GAAGGTGCTG GCGCCGCCGC CGCCGCCGCC TCGGCGGAGC CCAAGATCAT GAAAGTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	47.55	3.00e-36	146.00
IUUC-Aml-001461	Ailuropoda melanoleuca	83.83	0.00e+00	744.00
IUUC-Atr-002470	Amborella trichopoda	39.03	1.00e-43	171.00
IUUC-Apl-003241	Anas platyrhynchos	75.43	0.00e+00	659.00
IUUC-Aca-004511	Anolis carolinensis	73.52	0.00e+00	682.00
IUUC-Aly-005419	Arabidopsis lyrata	33.28	4.00e-53	202.00
IUUC-Ath-007350	Arabidopsis thaliana	33.05	4.00e-53	202.00
IUUC-Bta-013048	Bos taurus	83.85	0.00e+00	773.00
IUUC-Bdi-014506	Brachypodium distachyon	34.63	3.00e-48	186.00
IUUC-Bol-015326	Brassica oleracea	33.26	4.00e-47	182.00
IUUC-Bra-017098	Brassica rapa	33.03	8.00e-45	174.00
IUUC-Cel-018631	Caenorhabditis elegans	33.93	2.00e-70	259.00
IUUC-Cja-019976	Callithrix jacchus	87.43	0.00e+00	785.00
IUUC-Cfa-020092	Canis familiaris	86.50	0.00e+00	777.00
IUUC-Cpo-022388	Cavia porcellus	86.50	0.00e+00	766.00
IUUC-Csa-024087	Chlorocebus sabaeus	87.82	0.00e+00	790.00
IUUC-Cho-024834	Choloepus hoffmanni	86.11	0.00e+00	785.00
IUUC-Cin-025136	Ciona intestinalis	49.26	2.00e-110	392.00
IUUC-Csv-026009	Ciona savignyi	57.10	4.00e-79	288.00
IUUC-Cne-026833	Cryptococcus neoformans	27.47	3.00e-13	69.30
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	141.00
IUUC-Dre-028009	Danio rerio	61.14	6.00e-165	573.00
IUUC-Dno-028970	Dasypus novemcinctus	67.74	6.00e-173	600.00
IUUC-Dor-030519	Dipodomys ordii	85.40	0.00e+00	746.00
IUUC-Dme-032013	Drosophila melanogaster	45.03	2.00e-108	385.00
IUUC-Ete-032273	Echinops telfairi	85.44	0.00e+00	748.00
IUUC-Eca-033667	Equus caballus	83.99	0.00e+00	773.00
IUUC-Eeu-034865	Erinaceus europaeus	70.73	4.00e-119	421.00
IUUC-Fca-036179	Felis catus	83.79	0.00e+00	731.00
IUUC-Fal-037642	Ficedula albicollis	75.13	0.00e+00	729.00
IUUC-Gmo-039317	Gadus morhua	58.17	6.00e-164	570.00
IUUC-Gga-041264	Gallus gallus	75.58	0.00e+00	758.00
IUUC-Gma-042681	Glycine max	34.69	9.00e-44	171.00
IUUC-Ggo-044969	Gorilla gorilla	87.41	0.00e+00	756.00
IUUC-Hsa-046669	Homo sapiens	87.59	0.00e+00	789.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	93.79	0.00e+00	655.00
IUUC-Lch-050192	Latimeria chalumnae	78.04	9.00e-166	576.00
IUUC-Lpe-051401	Leersia perrieri	37.82	3.00e-36	146.00
IUUC-Loc-052846	Lepisosteus oculatus	76.01	2.00e-157	548.00
IUUC-Lma-053152	Leptosphaeria maculans	31.54	3.00e-14	73.60
IUUC-Laf-054278	Loxodonta africana	85.27	0.00e+00	740.00
IUUC-Mcc-055680	Macaca mulatta	88.14	0.00e+00	789.00
IUUC-Meu-056207	Macropus eugenii	68.17	6.00e-164	570.00
IUUC-Mtr-058674	Medicago truncatula	36.99	9.00e-40	157.00
IUUC-Mga-059894	Meleagris gallopavo	81.67	5.00e-177	613.00
IUUC-Mmr-061094	Microcebus murinus	87.59	0.00e+00	772.00
IUUC-Mdo-062728	Monodelphis domestica	79.10	0.00e+00	722.00
IUUC-Mmu-064088	Mus musculus	79.66	0.00e+00	772.00
IUUC-Mac-065526	Musa acuminata	32.07	5.00e-46	178.00
IUUC-Mpu-066282	Mustela putorius furo	83.06	0.00e+00	744.00
IUUC-Mlu-068158	Myotis lucifugus	85.04	0.00e+00	741.00
IUUC-Nle-069321	Nomascus leucogenys	87.59	0.00e+00	789.00
IUUC-Opr-071098	Ochotona princeps	93.09	7.00e-157	546.00
IUUC-Oan-072808	Ornithorhynchus anatinus	76.78	0.00e+00	672.00
IUUC-Oba-075114	Oryza barthii	37.64	6.00e-36	145.00
IUUC-Obr-076444	Oryza brachyantha	50.37	1.00e-31	130.00
IUUC-Ogl-077147	Oryza glaberrima	37.64	6.00e-36	145.00
IUUC-Ogu-078074	Oryza glumaepatula	33.72	1.00e-46	181.00
IUUC-Oin-079142	Oryza indica	37.62	5.00e-41	162.00
IUUC-Olo-080565	Oryza longistaminata	34.17	4.00e-45	175.00
IUUC-Ome-081155	Oryza meridionalis	36.02	1.00e-36	147.00
IUUC-Oni-082272	Oryza nivara	37.62	5.00e-41	162.00
IUUC-Opu-083339	Oryza punctata	35.63	1.00e-35	144.00
IUUC-Oru-085257	Oryza rufipogon	37.62	5.00e-41	162.00
IUUC-Osa-086257	Oryza sativa	37.95	9.00e-42	164.00
IUUC-Ola-086802	Oryzias latipes	63.48	2.00e-138	485.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.85	8.00e-26	111.00
IUUC-Oga-088495	Otolemur garnettii	87.04	0.00e+00	746.00
IUUC-Oar-089711	Ovis aries	83.16	0.00e+00	749.00
IUUC-Ptr-091439	Pan troglodytes	87.23	0.00e+00	783.00
IUUC-Pan-092641	Papio anubis	88.14	0.00e+00	789.00
IUUC-Psi-093518	Pelodiscus sinensis	76.47	0.00e+00	666.00
IUUC-Pma-094727	Petromyzon marinus	41.35	3.00e-45	176.00
IUUC-Ppa-095193	Physcomitrella patens	52.80	1.00e-35	144.00
IUUC-Pfo-096638	Poecilia formosa	64.21	5.00e-172	597.00
IUUC-Pab-098699	Pongo abelii	85.40	0.00e+00	781.00
IUUC-Pop-099549	Populus trichocarpa	37.21	4.00e-53	202.00
IUUC-Pca-100497	Procavia capensis	82.90	1.00e-131	462.00
IUUC-Ppe-101901	Prunus persica	35.25	2.00e-53	203.00
IUUC-Pva-102513	Pteropus vampyrus	69.60	1.00e-129	456.00
IUUC-Rno-104908	Rattus norvegicus	80.21	0.00e+00	818.00
IUUC-Sce-106332	Saccharomyces cerevisiae	31.53	2.00e-16	80.10
IUUC-Sha-106881	Sarcophilus harrisii	76.77	0.00e+00	665.00
IUUC-Spo-108223	Schizosaccharomyces pombe	27.51	3.00e-10	59.30
IUUC-Smo-108910	Selaginella moellendorffii	34.92	1.00e-38	154.00
IUUC-Sit-110766	Setaria italica	37.30	6.00e-35	141.00
IUUC-Sar-113648	Sorex araneus	79.92	9.00e-172	596.00
IUUC-Sbi-114273	Sorghum bicolor	50.38	8.00e-36	145.00
IUUC-Sre-115081	Sporisorium reilianum	27.31	4.00e-15	75.90
IUUC-Ssc-115820	Sus scrofa	87.04	0.00e+00	775.00
IUUC-Tgu-116845	Taeniopygia guttata	71.12	0.00e+00	645.00
IUUC-Tni-119780	Tetraodon nigroviridis	61.55	5.00e-167	580.00
IUUC-Tca-121558	Theobroma cacao	35.40	4.00e-52	199.00
IUUC-Tae-125801	Triticum aestivum	47.55	4.00e-36	145.00
IUUC-Tur-126783	Triticum urartu	38.00	4.00e-42	166.00
IUUC-Tme-127116	Tuber melanosporum	26.36	3.00e-09	56.60
IUUC-Tbe-127379	Tupaia belangeri	75.14	3.00e-176	611.00
IUUC-Ttr-128630	Tursiops truncatus	83.25	0.00e+00	783.00
IUUC-Uma-129639	Ustilago maydis	27.95	4.00e-14	72.40
IUUC-Vpa-130413	Vicugna pacos	72.08	6.00e-140	490.00
IUUC-Vvi-131599	Vitis vinifera	39.58	9.00e-42	164.00
IUUC-Xtr-132595	Xenopus tropicalis	81.39	4.00e-170	591.00
IUUC-Xma-134155	Xiphophorus maculatus	61.06	4.00e-168	584.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence