iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004097

Ensembl Protein ID

ENSAPLP00000015676.1

UniProt Accession

U3J848; U3J848_ANAPL

Genbank Protein ID

ENSAPLP00000015676

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ADON01052826

Gene Name

ING4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000015791.1	ENSAPLT00000016477.1	ENSAPLP00000015676.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.70e-10	38.9	196	243

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 196  TYC-LCHQVSYGE--MIGCDNpdCSiEWFHFACVGLT---TKPRGK-WFCPRCSQ 243
           69*.*******99..********999***********...899996.******97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

STGAYLAHGV QRIENLPFEL QRNFQLMRDL DQRTEDLKSE IDKLATEYIS NARTLSSEEK 60
LGLLKQIQEA YGKCKEFGDD KVQLAMQTYE MVDKHIRRLD TDLARFEADL KEKQIESSDY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAACTGGTG CATATCTGGC ACACGGCGTG CAACACAAGA ACAAATGCTG ATTTCTCCTA 60
GAGGAGAGGA GTAAAAAGCA GTGTGCTGCT GCATGAAACA TGGTTCATTT CTGCACAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	92.34	3.00e-118	417.00
IUUC-Atr-002906	Amborella trichopoda	33.60	2.00e-33	135.00
IUUC-Aca-004593	Anolis carolinensis	96.77	4.00e-123	433.00
IUUC-Ame-011133	Astyanax mexicanus	80.00	1.00e-112	398.00
IUUC-Bta-012699	Bos taurus	91.13	4.00e-118	416.00
IUUC-Bdi-014504	Brachypodium distachyon	35.80	4.00e-38	150.00
IUUC-Bol-015245	Brassica oleracea	32.64	3.00e-30	124.00
IUUC-Bra-017027	Brassica rapa	33.05	5.00e-31	127.00
IUUC-Cja-019988	Callithrix jacchus	93.55	2.00e-113	400.00
IUUC-Cfa-021282	Canis familiaris	92.74	2.00e-112	397.00
IUUC-Cpo-022011	Cavia porcellus	92.74	1.00e-121	428.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	34.29	1.00e-28	119.00
IUUC-Csa-023203	Chlorocebus sabaeus	93.55	2.00e-113	400.00
IUUC-Cin-025479	Ciona intestinalis	58.65	1.00e-74	271.00
IUUC-Csv-026288	Ciona savignyi	52.63	2.00e-70	258.00
IUUC-Dre-028264	Danio rerio	79.60	3.00e-111	393.00
IUUC-Dno-029766	Dasypus novemcinctus	92.34	3.00e-110	390.00
IUUC-Dor-031136	Dipodomys ordii	91.46	2.00e-91	328.00
IUUC-Dme-032200	Drosophila melanogaster	89.86	3.00e-40	158.00
IUUC-Eca-033565	Equus caballus	93.15	8.00e-122	429.00
IUUC-Eeu-034948	Erinaceus europaeus	76.52	3.00e-95	340.00
IUUC-Fca-036368	Felis catus	93.15	6.00e-113	399.00
IUUC-Fal-037120	Ficedula albicollis	95.97	1.00e-120	424.00
IUUC-Gmo-038982	Gadus morhua	79.12	1.00e-111	395.00
IUUC-Gga-040771	Gallus gallus	96.77	4.00e-123	433.00
IUUC-Gac-042184	Gasterosteus aculeatus	79.59	3.00e-109	387.00
IUUC-Gma-044339	Glycine max	30.56	2.00e-32	131.00
IUUC-Ggo-045559	Gorilla gorilla	93.55	2.00e-113	400.00
IUUC-Hsa-046852	Homo sapiens	93.55	2.00e-113	400.00
IUUC-Hvu-047046	Hordeum vulgare	36.48	5.00e-37	147.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	92.74	2.00e-121	427.00
IUUC-Kpa-049229	Komagataella pastoris	59.18	1.00e-16	79.30
IUUC-Lpe-050822	Leersia perrieri	34.57	1.00e-37	149.00
IUUC-Laf-054057	Loxodonta africana	93.15	6.00e-113	399.00
IUUC-Mcc-055212	Macaca mulatta	87.60	1.00e-107	381.00
IUUC-Meu-056511	Macropus eugenii	91.91	2.00e-112	397.00
IUUC-Mtr-058288	Medicago truncatula	31.48	1.00e-31	129.00
IUUC-Mga-059967	Meleagris gallopavo	96.75	8.00e-121	425.00
IUUC-Mmr-060843	Microcebus murinus	91.13	3.00e-118	416.00
IUUC-Mdo-062357	Monodelphis domestica	92.34	5.00e-121	426.00
IUUC-Mmu-064093	Mus musculus	92.74	1.00e-121	428.00
IUUC-Mac-064625	Musa acuminata	33.33	1.00e-34	139.00
IUUC-Mpu-066923	Mustela putorius furo	81.45	6.00e-90	322.00
IUUC-Mlu-067754	Myotis lucifugus	86.06	4.00e-110	390.00
IUUC-Nle-069062	Nomascus leucogenys	93.55	2.00e-113	400.00
IUUC-Opr-070207	Ochotona princeps	89.83	3.00e-109	387.00
IUUC-Ont-072446	Oreochromis niloticus	79.52	3.00e-110	390.00
IUUC-Ocu-074235	Oryctolagus cuniculus	92.74	2.00e-112	397.00
IUUC-Obr-076266	Oryza brachyantha	34.57	4.00e-36	144.00
IUUC-Ogl-077118	Oryza glaberrima	33.61	2.00e-35	141.00
IUUC-Oin-079049	Oryza indica	34.52	1.00e-34	139.00
IUUC-Ome-081291	Oryza meridionalis	34.02	7.00e-36	143.00
IUUC-Oni-082218	Oryza nivara	34.52	1.00e-34	139.00
IUUC-Opu-084171	Oryza punctata	34.41	4.00e-36	144.00
IUUC-Osa-085563	Oryza sativa	34.02	7.00e-36	143.00
IUUC-Ola-086429	Oryzias latipes	74.70	4.00e-101	360.00
IUUC-Oga-089123	Otolemur garnettii	93.15	6.00e-113	399.00
IUUC-Oar-089524	Ovis aries	91.13	4.00e-118	416.00
IUUC-Ptr-090908	Pan troglodytes	93.15	6.00e-113	399.00
IUUC-Pan-092837	Papio anubis	92.74	9.00e-119	418.00
IUUC-Psi-093828	Pelodiscus sinensis	99.57	1.00e-117	415.00
IUUC-Ppa-096009	Physcomitrella patens	32.41	2.00e-31	128.00
IUUC-Pfo-096617	Poecilia formosa	79.12	3.00e-110	390.00
IUUC-Pab-097978	Pongo abelii	96.19	2.00e-108	384.00
IUUC-Pop-099415	Populus trichocarpa	73.68	1.00e-26	112.00
IUUC-Pca-100475	Procavia capensis	60.89	1.00e-76	278.00
IUUC-Ppe-101441	Prunus persica	32.68	1.00e-35	142.00
IUUC-Pva-102325	Pteropus vampyrus	93.15	8.00e-122	429.00
IUUC-Rno-105178	Rattus norvegicus	91.13	6.00e-127	445.00
IUUC-Sha-106773	Sarcophilus harrisii	92.34	5.00e-121	426.00
IUUC-Smo-109441	Selaginella moellendorffii	31.35	7.00e-38	149.00
IUUC-Sit-109827	Setaria italica	35.39	3.00e-35	140.00
IUUC-Sly-111750	Solanum lycopersicum	34.98	2.00e-35	141.00
IUUC-Stu-112250	Solanum tuberosum	34.98	2.00e-35	141.00
IUUC-Sbi-114826	Sorghum bicolor	33.74	2.00e-36	145.00
IUUC-Sre-115124	Sporisorium reilianum	51.85	6.00e-23	102.00
IUUC-Ssc-115797	Sus scrofa	93.22	3.00e-103	367.00
IUUC-Tgu-117270	Taeniopygia guttata	96.77	4.00e-123	433.00
IUUC-Tru-118253	Takifugu rubripes	78.40	2.00e-110	391.00
IUUC-Tca-121597	Theobroma cacao	69.84	2.00e-28	118.00
IUUC-Tae-123043	Triticum aestivum	36.80	1.00e-36	145.00
IUUC-Tbe-127558	Tupaia belangeri	92.34	3.00e-118	417.00
IUUC-Ttr-128300	Tursiops truncatus	97.27	6.00e-64	236.00
IUUC-Uma-129581	Ustilago maydis	57.63	2.00e-21	97.40
IUUC-Xma-133297	Xiphophorus maculatus	61.69	3.00e-80	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence