iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008158

Ensembl Protein ID

CADACLAP00002728

UniProt Accession

A1CRM2; A1CRM2_ASPCL

Genbank Protein ID

EAW08293.1

Protein Name

IQ and HECT domain protein

Genbank Nucleotide ID

DS027059

Gene Name

ACLA_030260

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00002775	CADACLAT00002775	CADACLAP00002728

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-86	290.2	850	1226

Active Site

Position(s)	Description	Evidence
1194	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp....................ehlkl 70
           lk+ ++++f +     E+g+d gGvt+efl+ ++ e +++  g  l++end++ l+pnp++  +                      + l+ 
   Q: 850  LKEPIQISFIDkfdtvEAGIDGGGVTKEFLTSVTTEAFKAGSGPKLFEENDQHLLYPNPAAVEQRRealrqlgfvenspewnervrDLLRR 940
           6778899999999999*************************8888889*************98766************************* PP
   S: 71   FeflGrllgkalqdgrlldlplsksfyklllgk............klsledleevdpelykslkeikenaesdieelgldltfsvseei.. 147
           +eflGr++gk+l++g l+d++++++f+ +   +            + +l+dl+++d+ ly+ l ++k++   d+e+ +l++t+s  ++i  
   Q: 941  YEFLGRIIGKCLYEGILVDVNFAPFFLLKWALTggvgsaqretayRANLNDLKDLDQGLYQGLLQLKNY-PGDVEDFALNFTVS--DTIpl 1028
           **************************988744445666777777789********************99.56999876666665..55556 PP
   S: 148  ...lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketk 234
               + t +++Lk+ G++i Vtn+N+  Y++ ++ yrl+ + + q++af +G+  +i++++ls+F++ el++l++Ge  +idv dl+++t 
   Q: 1029 pdgGSRTVTRDLKSHGSDIAVTNQNRLVYISYIARYRLQVQPALQTHAFLQGLGHIIQPSWLSMFNQAELQTLVSGEsGDIDVADLRRNTL 1119
           77677778888*******************************************************************************9 PP
   S: 235  y.....kggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeil 319
           y      g+ +e++p+++ Fwev+e++s+eer++ L+FvT+++r+Pl Gf  l+pr f ir+ +++++rlPs +TC+n+LkLP+Yss ++l
   Q: 1120 YggvytIGDDKEEHPTVKLFWEVMEKMSNEERQKVLRFVTSTPRAPLLGFSHLNPR-FSIRDsSEDQERLPSTSTCVNLLKLPRYSSAKVL 1209
           866556455579******************************************99.8999946666************************ PP
   S: 320  kekLlyAieetkgFels 336
           +ekLlyAi++++gF+ls
   Q: 1210 REKLLYAINSGAGFDLS 1226
           **************985 PP

Organism

Aspergillus clavatus

Protein Sequence
(Fasta)

MFQSFTGNSR RPRQVNLGGR NTNPFAAYPP GRHSAPAPGP QNTLAIAQQE RLLRQQERER 60
LGATRKIQRT WRGYSSRKIT HNTWRTEWDT AERQRTGASL PFEDKAGYRE DNFKASMPYG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTCAAT CATTCACGGG GAACTCTCGC CGTCCACGGC AGGTCAATCT CGGGGGCCGC 60
AATACGAATC CCTTCGCTGC TTACCCTCCC GGTAGACACT CTGCACCTGC TCCAGGTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

act:ACLA_030260

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	34.42	8.00e-80	290.00
IUUC-Aml-001355	Ailuropoda melanoleuca	35.74	5.00e-84	304.00
IUUC-Atr-003017	Amborella trichopoda	33.39	4.00e-80	291.00
IUUC-Apl-003731	Anas platyrhynchos	36.38	1.00e-86	312.00
IUUC-Aca-005248	Anolis carolinensis	36.38	2.00e-86	312.00
IUUC-Aly-005768	Arabidopsis lyrata	37.58	1.00e-81	296.00
IUUC-Ath-007269	Arabidopsis thaliana	39.32	3.00e-82	298.00
IUUC-Ago-007748	Ashbya gossypii	38.81	1.00e-78	286.00
IUUC-Afl-008398	Aspergillus flavus	79.40	0.00e+00	1788.00
IUUC-Afu-008937	Aspergillus fumigatus	88.83	0.00e+00	2045.00
IUUC-Ani-009252	Aspergillus nidulans	76.12	0.00e+00	1785.00
IUUC-Ang-009773	Aspergillus niger	81.77	0.00e+00	1865.00
IUUC-Aor-009940	Aspergillus oryzae	79.48	0.00e+00	1789.00
IUUC-Ate-010395	Aspergillus terreus	80.37	0.00e+00	1760.00
IUUC-Ame-010769	Astyanax mexicanus	35.41	8.00e-60	223.00
IUUC-Bgr-012269	Blumeria graminis	61.61	3.00e-171	592.00
IUUC-Bta-012841	Bos taurus	36.55	9.00e-87	313.00
IUUC-Bci-013743	Botrytis cinerea	45.00	0.00e+00	933.00
IUUC-Bdi-014502	Brachypodium distachyon	38.89	9.00e-82	296.00
IUUC-Bol-015093	Brassica oleracea	38.90	1.00e-81	296.00
IUUC-Bra-016722	Brassica rapa	38.90	4.00e-82	298.00
IUUC-Cel-018447	Caenorhabditis elegans	33.06	4.00e-60	224.00
IUUC-Cja-019743	Callithrix jacchus	35.64	3.00e-83	301.00
IUUC-Cfa-021031	Canis familiaris	35.91	8.00e-85	306.00
IUUC-Cpo-022401	Cavia porcellus	36.08	1.00e-84	306.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	37.18	1.00e-68	251.00
IUUC-Csa-024107	Chlorocebus sabaeus	35.57	1.00e-83	303.00
IUUC-Cho-024750	Choloepus hoffmanni	42.44	3.00e-75	275.00
IUUC-Cin-025750	Ciona intestinalis	31.05	2.00e-60	226.00
IUUC-Csv-026016	Ciona savignyi	33.73	3.00e-68	252.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	41.65	0.00e+00	851.00
IUUC-Cne-026841	Cryptococcus neoformans	37.67	1.00e-89	322.00
IUUC-Cme-027265	Cyanidioschyzon merolae	39.36	3.00e-78	285.00
IUUC-Dre-028196	Danio rerio	37.24	8.00e-89	320.00
IUUC-Dno-029024	Dasypus novemcinctus	36.08	1.00e-85	309.00
IUUC-Dor-030938	Dipodomys ordii	34.51	8.00e-65	240.00
IUUC-Dse-031416	Dothistroma septosporum	42.83	0.00e+00	848.00
IUUC-Dme-031946	Drosophila melanogaster	36.69	5.00e-78	284.00
IUUC-Ete-033041	Echinops telfairi	29.94	2.00e-42	166.00
IUUC-Eca-033828	Equus caballus	36.21	2.00e-85	309.00
IUUC-Eeu-035201	Erinaceus europaeus	30.68	3.00e-43	169.00
IUUC-Fca-035907	Felis catus	35.85	1.00e-84	306.00
IUUC-Fal-037389	Ficedula albicollis	36.38	3.00e-86	311.00
IUUC-Fox-037788	Fusarium oxysporum	44.75	0.00e+00	716.00
IUUC-Fso-038088	Fusarium solani	42.32	0.00e+00	674.00
IUUC-Gmo-039412	Gadus morhua	32.52	6.00e-67	247.00
IUUC-Ggr-039941	Gaeumannomyces graminis	40.19	0.00e+00	751.00
IUUC-Gga-040310	Gallus gallus	36.21	1.00e-85	310.00
IUUC-Gac-042088	Gasterosteus aculeatus	31.91	6.00e-66	244.00
IUUC-Gma-042819	Glycine max	37.29	2.00e-73	269.00
IUUC-Ggo-045031	Gorilla gorilla	35.74	4.00e-84	304.00
IUUC-Hsa-045880	Homo sapiens	35.74	4.00e-84	305.00
IUUC-Hvu-047102	Hordeum vulgare	34.25	3.00e-79	288.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	34.51	4.00e-66	243.00
IUUC-Kpa-049307	Komagataella pastoris	33.61	5.00e-79	287.00
IUUC-Lch-050664	Latimeria chalumnae	29.80	6.00e-67	247.00
IUUC-Lpe-050755	Leersia perrieri	38.99	2.00e-80	292.00
IUUC-Loc-052218	Lepisosteus oculatus	37.20	3.00e-87	315.00
IUUC-Lma-053096	Leptosphaeria maculans	49.73	0.00e+00	1033.00
IUUC-Laf-053902	Loxodonta africana	31.98	4.00e-67	248.00
IUUC-Mcc-055127	Macaca mulatta	35.74	3.00e-84	305.00
IUUC-Meu-056527	Macropus eugenii	37.26	4.00e-54	204.00
IUUC-Mor-057021	Magnaporthe oryzae	40.90	0.00e+00	774.00
IUUC-Mpo-057570	Magnaporthe poae	43.10	0.00e+00	714.00
IUUC-Mtr-057671	Medicago truncatula	38.24	3.00e-82	298.00
IUUC-Mla-059124	Melampsora laricipopulina	40.88	2.00e-99	353.00
IUUC-Mga-059581	Meleagris gallopavo	36.21	6.00e-86	310.00
IUUC-Mvi-060445	Microbotryum violaceum	38.60	5.00e-120	424.00
IUUC-Mmr-061360	Microcebus murinus	35.74	1.00e-84	306.00
IUUC-Mdo-062194	Monodelphis domestica	36.21	8.00e-87	313.00
IUUC-Mmu-064189	Mus musculus	35.74	5.00e-84	304.00
IUUC-Mac-065275	Musa acuminata	37.97	5.00e-81	293.00
IUUC-Mpu-066439	Mustela putorius furo	36.08	1.00e-84	306.00
IUUC-Mlu-068228	Myotis lucifugus	36.03	3.00e-85	308.00
IUUC-Nfi-068280	Neosartorya fischeri	88.66	0.00e+00	2016.00
IUUC-Ncr-068869	Neurospora crassa	40.92	0.00e+00	748.00
IUUC-Nle-069687	Nomascus leucogenys	35.28	8.00e-84	303.00
IUUC-Opr-070554	Ochotona princeps	32.18	4.00e-67	248.00
IUUC-Ont-071836	Oreochromis niloticus	36.72	5.00e-86	310.00
IUUC-Oan-072800	Ornithorhynchus anatinus	36.03	2.00e-85	309.00
IUUC-Ocu-074587	Oryctolagus cuniculus	36.25	1.00e-85	310.00
IUUC-Oba-075213	Oryza barthii	38.45	2.00e-83	302.00
IUUC-Obr-076320	Oryza brachyantha	38.65	1.00e-83	303.00
IUUC-Ogl-077093	Oryza glaberrima	38.65	2.00e-84	305.00
IUUC-Ogu-078947	Oryza glumaepatula	37.55	3.00e-80	291.00
IUUC-Oin-080058	Oryza indica	38.65	9.00e-84	303.00
IUUC-Olo-080742	Oryza longistaminata	38.65	4.00e-84	305.00
IUUC-Ome-081741	Oryza meridionalis	37.42	2.00e-78	285.00
IUUC-Oni-082385	Oryza nivara	37.55	3.00e-80	291.00
IUUC-Opu-083529	Oryza punctata	38.85	1.00e-84	306.00
IUUC-Oru-085128	Oryza rufipogon	36.44	1.00e-73	270.00
IUUC-Osa-085557	Oryza sativa	38.65	2.00e-83	301.00
IUUC-Ola-087209	Oryzias latipes	36.90	5.00e-87	314.00
IUUC-Olu-087902	Ostreococcus lucimarinus	37.30	1.00e-68	251.00
IUUC-Oga-088776	Otolemur garnettii	35.91	1.00e-84	306.00
IUUC-Oar-089441	Ovis aries	36.55	1.00e-86	313.00
IUUC-Ptr-091273	Pan troglodytes	35.74	3.00e-84	305.00
IUUC-Pan-091981	Papio anubis	35.74	3.00e-84	305.00
IUUC-Psi-093251	Pelodiscus sinensis	30.86	8.00e-55	207.00
IUUC-Pma-094738	Petromyzon marinus	35.76	4.00e-81	294.00
IUUC-Pno-095132	Phaeosphaeria nodorum	51.27	0.00e+00	799.00
IUUC-Ppa-095544	Physcomitrella patens	39.00	3.00e-84	305.00
IUUC-Pfo-097511	Poecilia formosa	37.24	9.00e-87	313.00
IUUC-Pab-098634	Pongo abelii	33.51	2.00e-72	266.00
IUUC-Pop-099574	Populus trichocarpa	36.23	1.00e-70	259.00
IUUC-Pca-100987	Procavia capensis	41.65	7.00e-78	283.00
IUUC-Ppe-101281	Prunus persica	38.24	4.00e-81	295.00
IUUC-Pva-102887	Pteropus vampyrus	32.59	4.00e-68	251.00
IUUC-Pgr-103513	Puccinia graminis	37.71	2.00e-110	391.00
IUUC-Ptt-103967	Puccinia triticina	39.97	9.00e-99	353.00
IUUC-Pte-104105	Pyrenophora teres	49.30	0.00e+00	1025.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	49.80	0.00e+00	1012.00
IUUC-Rno-106028	Rattus norvegicus	30.20	3.00e-52	198.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.51	1.00e-82	299.00
IUUC-Sha-107108	Sarcophilus harrisii	33.73	4.00e-74	271.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	32.95	1.00e-93	336.00
IUUC-Spo-108097	Schizosaccharomyces pombe	31.59	6.00e-101	360.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	45.04	0.00e+00	919.00
IUUC-Smo-109537	Selaginella moellendorffii	40.83	2.00e-85	308.00
IUUC-Sit-110457	Setaria italica	38.14	5.00e-75	274.00
IUUC-Sly-111362	Solanum lycopersicum	37.29	3.00e-74	271.00
IUUC-Sar-113687	Sorex araneus	33.82	1.00e-40	159.00
IUUC-Sbi-114433	Sorghum bicolor	36.24	8.00e-83	300.00
IUUC-Sre-115038	Sporisorium reilianum	43.16	3.00e-96	345.00
IUUC-Ssc-116103	Sus scrofa	32.38	5.00e-67	248.00
IUUC-Tgu-116729	Taeniopygia guttata	36.38	4.00e-87	314.00
IUUC-Tru-118068	Takifugu rubripes	37.41	6.00e-88	317.00
IUUC-Tsy-118942	Tarsius syrichta	45.09	6.00e-59	221.00
IUUC-Tni-120732	Tetraodon nigroviridis	36.66	7.00e-81	293.00
IUUC-Tca-121770	Theobroma cacao	38.45	6.00e-83	300.00
IUUC-Tre-121892	Trichoderma reesei	40.15	0.00e+00	748.00
IUUC-Tvi-122354	Trichoderma virens	39.82	0.00e+00	787.00
IUUC-Tae-125229	Triticum aestivum	37.50	2.00e-79	289.00
IUUC-Tur-126086	Triticum urartu	34.42	8.00e-80	290.00
IUUC-Tme-127102	Tuber melanosporum	40.43	0.00e+00	749.00
IUUC-Tbe-127351	Tupaia belangeri	37.62	3.00e-64	238.00
IUUC-Ttr-129061	Tursiops truncatus	40.90	1.00e-77	282.00
IUUC-Uma-129343	Ustilago maydis	42.95	7.00e-99	353.00
IUUC-Vda-129748	Verticillium dahliae	45.90	0.00e+00	672.00
IUUC-Vvi-131524	Vitis vinifera	39.61	1.00e-80	293.00
IUUC-Xtr-132094	Xenopus tropicalis	36.03	7.00e-85	306.00
IUUC-Xma-133923	Xiphophorus maculatus	37.24	9.00e-87	313.00
IUUC-Yli-134496	Yarrowia lipolytica	37.39	2.00e-91	328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence