iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-064439

Ensembl Protein ID

GSMUA_Achr9P23740_001

UniProt Accession

M0U2Y1; M0U2Y1_MUSAM

Protein Name

Katanin p80 WD40 repeat-containing subunit B1 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr9G23740_001	GSMUA_Achr9T23740_001	GSMUA_Achr9P23740_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-37	126.8	152	190
UBD/Beta-Prp	7.90e-56	190.3	25	276

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt +v++++f +d + +vsG+ D+ +k+WDl+ g+ll+
   Q: 152  GHTRGVNAIKFtPDgRWVVSGGEDNIVKLWDLTAGKLLH 190
           8***********99999******************9986 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           +h+s ++c+k+  + +++l+tg++d+++ +w + +++++ slsgh ++v +v+f++++ + + g+  + ik+wdl+  k+++tl+gh 
   Q: 25   AHSSNVNCLKIgRKTSRVLVTGGDDNKVNIWAIGKPNAIMSLSGHMSAVESVSFDSSEVLVAAGAASGSIKLWDLEEAKIIRTLTGHR 112
           799999*****999********************************************999999999********************* PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           ++  +++f+p g++++sGs d  +++wd++ + c++ t +gh++ vn +++ pdg+ +vsG+ D++v+lWdl  gkll++++  h+++
   Q: 113  SNCIAVDFHPFGEFFASGSLDTNLKIWDMRRKGCIH-TYKGHTRGVNAIKFTPDGRWVVSGGEDNIVKLWDLTAGKLLHDFKL-HEGQ 198
           ************************************.********************************************98.**** PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlq..........tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           +++++f++n + l++gs d+tvk+wdl+          ++e ++     t+ v+s+ f p++  l++g  ++s++i+  
   Q: 199  IQCIDFHPNEFLLATGSADRTVKFWDLEtfeligsagpEKESIQYNLSSTSGVRSMTFNPDGRTLLCGL-HESLKIFSW 276
           ****************************76666666654444555556779********9999999995.777777543 PP

Organism

Musa acuminata

Functional Description
(View)

May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.

Protein Sequence
(Fasta)

MATTKRAYKL RILLLLLVNL EEFVAHSSNV NCLKIGRKTS RVLVTGGDDN KVNIWAIGKP 60
NAIMSLSGHM SAVESVSFDS SEVLVAAGAA SGSIKLWDLE EAKIIRTLTG HRSNCIAVDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACCA CCAAGCGCGC CTACAAGTTA CGTATCCTTT TGTTGCTTCT GTTGAATTCA 60
AAATTTTTTT CCCTTAGGGT ATTTTTTATG GTAATTAGGG AAAGTCCATC TTTGGAATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0472--Membrane
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0051013--P:microtubule severing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	61.28	1.00e-162	567.00
IUUC-Apl-003305	Anas platyrhynchos	51.99	2.00e-100	359.00
IUUC-Aly-005711	Arabidopsis lyrata	59.00	2.00e-178	618.00
IUUC-Bdi-014652	Brachypodium distachyon	68.82	0.00e+00	668.00
IUUC-Cfa-020139	Canis familiaris	44.54	1.00e-95	343.00
IUUC-Csa-023546	Chlorocebus sabaeus	51.01	9.00e-97	347.00
IUUC-Dse-031558	Dothistroma septosporum	30.41	7.00e-27	115.00
IUUC-Fal-037387	Ficedula albicollis	50.62	3.00e-100	358.00
IUUC-Hvu-047649	Hordeum vulgare	67.88	0.00e+00	663.00
IUUC-Lpe-051554	Leersia perrieri	66.60	0.00e+00	672.00
IUUC-Obr-076385	Oryza brachyantha	66.80	0.00e+00	671.00
IUUC-Ogl-077427	Oryza glaberrima	70.75	0.00e+00	670.00
IUUC-Ogu-079022	Oryza glumaepatula	57.87	2.00e-152	532.00
IUUC-Ome-081239	Oryza meridionalis	71.16	0.00e+00	638.00
IUUC-Osa-086267	Oryza sativa	52.85	2.00e-152	532.00
IUUC-Pca-100357	Procavia capensis	56.85	7.00e-74	271.00
IUUC-Sit-110360	Setaria italica	69.68	0.00e+00	679.00
IUUC-Stu-112462	Solanum tuberosum	68.21	0.00e+00	663.00
IUUC-Tsy-119036	Tarsius syrichta	59.65	9.00e-39	154.00
IUUC-Xtr-132915	Xenopus tropicalis	50.50	3.00e-96	345.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence