iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000017697.4	ENSXETT00000038396.3	ENSXETP00000038396.3
ENSXETG00000017697.4	ENSXETT00000065386.1	ENSXETP00000062659.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.90e-34	117.0	4518	4673

Active Site

Position(s)	Description	Evidence
4607	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyen 78
           Rl++e+ +l+++ p    +++++++++e  l+ ++vli+Gp+dtpY++g+F+++++fp+dYP +PP v+++t+     +f+Pn+y++
   Q: 4518 RLAQEAVTLSTSLPlsssSSVFVRCDEE-RLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTgghsvRFNPNLYND 4603
           8999999999998877768899999999.6********************************************************* PP
   S: 79   GkvClsilk.....eeekWsp.alsvesvllsiqsll..aepnpesplneeaa...ellkknreeykkkvr 138
           GkvClsil+     +eekW+p ++s+ +vl+siqsl+  +ep++++p +e+++      +++ +ey+ ++r
   Q: 4604 GKVCLSILNtwhgrPEEKWNPqTSSFLQVLVSIQSLIlvSEPYFNEPGYERSRgtpG-GTQSSREYDGNIR 4673
           ********7788889******8899***********9999*********99985533.3444445888887 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MAAGASEWLL LRDGCFRCDE QGVSSLSYHP SLNAILAVTN RGSIKVIDGT SGAILQSSAA 60
HVKPGGRVRC QYFPTVDKVI FVDDYAVGCR KDLNGILLLE TALQTPVSKP DDVIQLELPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG GGGCCTCGGA GTGGCTGCTC CTAAGAGACG GCTGTTTTCG CTGCGACGAG 60
CAGGGTGTGA GCAGCTTGTC CTACCACCCG TCTCTTAATG CGATCCTGGC TGTCACTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR022103--BIRC6
IPR008979--Galactose-bd-like
IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom

PROSITE

PS50143--BIR_REPEAT_2
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00653--BIR
PF12356--BIRC6
PF00179--UQ_con

SMART

SM00238--BIR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006915--P:apoptotic process
GO:0032465--P:regulation of cytokinesis
GO:0009966--P:regulation of signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000597	Aegilops tauschii	43.82	1.00e-32	135.00
IUUC-Aml-001583	Ailuropoda melanoleuca	83.63	0.00e+00	7324.00
IUUC-Atr-003108	Amborella trichopoda	43.41	1.00e-44	173.00
IUUC-Apl-004144	Anas platyrhynchos	86.39	0.00e+00	5094.00
IUUC-Aca-005257	Anolis carolinensis	82.96	0.00e+00	7280.00
IUUC-Aly-005551	Arabidopsis lyrata	41.86	2.00e-42	166.00
IUUC-Ath-007217	Arabidopsis thaliana	45.98	1.00e-42	167.00
IUUC-Acl-008031	Aspergillus clavatus	51.28	2.00e-32	135.00
IUUC-Afl-008480	Aspergillus flavus	45.30	4.00e-28	120.00
IUUC-Afu-009040	Aspergillus fumigatus	43.04	2.00e-31	131.00
IUUC-Ang-009816	Aspergillus niger	47.86	6.00e-28	119.00
IUUC-Aor-010121	Aspergillus oryzae	43.24	8.00e-25	109.00
IUUC-Ate-010487	Aspergillus terreus	50.43	3.00e-31	130.00
IUUC-Ame-011337	Astyanax mexicanus	73.93	0.00e+00	6180.00
IUUC-Bta-012501	Bos taurus	82.87	0.00e+00	7198.00
IUUC-Bdi-014931	Brachypodium distachyon	46.15	3.00e-45	176.00
IUUC-Bol-016151	Brassica oleracea	47.13	9.00e-45	174.00
IUUC-Bra-017244	Brassica rapa	47.13	7.00e-45	174.00
IUUC-Cel-018661	Caenorhabditis elegans	50.94	7.00e-68	251.00
IUUC-Cja-018746	Callithrix jacchus	83.57	0.00e+00	7252.00
IUUC-Cfa-020170	Canis familiaris	83.83	0.00e+00	7221.00
IUUC-Cpo-022138	Cavia porcellus	84.65	0.00e+00	4996.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	44.13	2.00e-43	168.00
IUUC-Csa-023927	Chlorocebus sabaeus	83.37	0.00e+00	7242.00
IUUC-Cho-024890	Choloepus hoffmanni	77.16	0.00e+00	1540.00
IUUC-Cne-026995	Cryptococcus neoformans	42.45	2.00e-36	147.00
IUUC-Dre-027941	Danio rerio	74.40	0.00e+00	4957.00
IUUC-Dno-028913	Dasypus novemcinctus	82.51	0.00e+00	7190.00
IUUC-Dor-030715	Dipodomys ordii	78.72	0.00e+00	1565.00
IUUC-Dse-031232	Dothistroma septosporum	45.05	2.00e-38	154.00
IUUC-Dme-031592	Drosophila melanogaster	52.66	0.00e+00	654.00
IUUC-Ete-032587	Echinops telfairi	65.78	0.00e+00	1652.00
IUUC-Eca-033819	Equus caballus	83.72	0.00e+00	7267.00
IUUC-Eeu-034863	Erinaceus europaeus	73.80	0.00e+00	2107.00
IUUC-Fca-035505	Felis catus	81.34	0.00e+00	7014.00
IUUC-Fal-037318	Ficedula albicollis	84.62	0.00e+00	7420.00
IUUC-Gmo-039521	Gadus morhua	81.75	0.00e+00	1660.00
IUUC-Ggr-040040	Gaeumannomyces graminis	47.71	8.00e-34	139.00
IUUC-Gga-040728	Gallus gallus	84.58	0.00e+00	7343.00
IUUC-Gac-042251	Gasterosteus aculeatus	82.52	0.00e+00	1723.00
IUUC-Gma-043816	Glycine max	37.33	4.00e-35	143.00
IUUC-Ggo-045562	Gorilla gorilla	84.58	0.00e+00	1355.00
IUUC-Hsa-046339	Homo sapiens	83.65	0.00e+00	7213.00
IUUC-Hvu-047441	Hordeum vulgare	46.70	2.00e-46	179.00
IUUC-Itr-048099	Ictidomys tridecemlineatus	81.95	0.00e+00	2254.00
IUUC-Lch-050164	Latimeria chalumnae	80.84	0.00e+00	6942.00
IUUC-Lpe-051294	Leersia perrieri	42.11	1.00e-44	174.00
IUUC-Loc-052800	Lepisosteus oculatus	80.48	0.00e+00	6950.00
IUUC-Laf-054034	Loxodonta africana	83.25	0.00e+00	7263.00
IUUC-Mcc-055267	Macaca mulatta	83.54	0.00e+00	7251.00
IUUC-Meu-056461	Macropus eugenii	84.83	0.00e+00	1092.00
IUUC-Mpo-057396	Magnaporthe poae	49.02	1.00e-34	141.00
IUUC-Mtr-057797	Medicago truncatula	47.80	1.00e-46	180.00
IUUC-Mla-059114	Melampsora laricipopulina	38.03	1.00e-37	151.00
IUUC-Mga-059594	Meleagris gallopavo	84.37	0.00e+00	6955.00
IUUC-Mvi-060389	Microbotryum violaceum	41.18	1.00e-30	128.00
IUUC-Mmr-061179	Microcebus murinus	83.53	0.00e+00	7238.00
IUUC-Mdo-062990	Monodelphis domestica	84.34	0.00e+00	7248.00
IUUC-Mmu-063825	Mus musculus	82.43	0.00e+00	7143.00
IUUC-Mac-064945	Musa acuminata	39.47	2.00e-42	166.00
IUUC-Mpu-065908	Mustela putorius furo	84.74	0.00e+00	4739.00
IUUC-Mlu-067106	Myotis lucifugus	82.48	0.00e+00	7190.00
IUUC-Nfi-068366	Neosartorya fischeri	50.43	4.00e-31	130.00
IUUC-Nle-069347	Nomascus leucogenys	83.76	0.00e+00	7252.00
IUUC-Opr-070799	Ochotona princeps	73.87	0.00e+00	2038.00
IUUC-Ont-072046	Oreochromis niloticus	75.31	0.00e+00	6253.00
IUUC-Oan-073415	Ornithorhynchus anatinus	85.57	0.00e+00	3043.00
IUUC-Ocu-074556	Oryctolagus cuniculus	83.34	0.00e+00	7185.00
IUUC-Oba-075870	Oryza barthii	38.93	1.00e-45	177.00
IUUC-Obr-076823	Oryza brachyantha	48.35	1.00e-44	173.00
IUUC-Ogl-077412	Oryza glaberrima	38.93	8.00e-46	177.00
IUUC-Ogu-077966	Oryza glumaepatula	38.93	1.00e-45	177.00
IUUC-Oin-080009	Oryza indica	39.69	1.00e-45	176.00
IUUC-Olo-080416	Oryza longistaminata	40.24	8.00e-38	152.00
IUUC-Ome-081384	Oryza meridionalis	46.15	3.00e-37	149.00
IUUC-Oni-082326	Oryza nivara	39.69	2.00e-45	176.00
IUUC-Opu-083659	Oryza punctata	46.15	5.00e-44	171.00
IUUC-Oru-085077	Oryza rufipogon	38.93	1.00e-45	177.00
IUUC-Osa-086014	Oryza sativa	38.93	1.00e-45	177.00
IUUC-Ola-087459	Oryzias latipes	77.36	0.00e+00	2638.00
IUUC-Oga-088251	Otolemur garnettii	81.64	0.00e+00	6916.00
IUUC-Oar-090367	Ovis aries	83.20	0.00e+00	7237.00
IUUC-Ptr-091512	Pan troglodytes	83.65	0.00e+00	7239.00
IUUC-Pan-092222	Papio anubis	83.20	0.00e+00	7228.00
IUUC-Pma-094574	Petromyzon marinus	62.65	0.00e+00	1767.00
IUUC-Pno-095065	Phaeosphaeria nodorum	46.03	1.00e-28	122.00
IUUC-Ppa-095592	Physcomitrella patens	30.31	6.00e-53	202.00
IUUC-Pfo-097086	Poecilia formosa	74.15	0.00e+00	6370.00
IUUC-Pab-098390	Pongo abelii	82.43	0.00e+00	7063.00
IUUC-Pop-099782	Populus trichocarpa	43.96	1.00e-40	160.00
IUUC-Pca-101036	Procavia capensis	77.09	0.00e+00	3493.00
IUUC-Ppe-101722	Prunus persica	45.05	5.00e-43	169.00
IUUC-Pva-103053	Pteropus vampyrus	79.50	0.00e+00	3029.00
IUUC-Pte-104333	Pyrenophora teres	41.29	3.00e-43	171.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	44.63	5.00e-43	169.00
IUUC-Rno-106049	Rattus norvegicus	81.77	0.00e+00	5764.00
IUUC-Sha-107483	Sarcophilus harrisii	81.73	0.00e+00	6876.00
IUUC-Smo-108758	Selaginella moellendorffii	38.91	1.00e-42	168.00
IUUC-Sit-110087	Setaria italica	46.07	4.00e-43	168.00
IUUC-Sly-110929	Solanum lycopersicum	38.95	6.00e-45	175.00
IUUC-Stu-112756	Solanum tuberosum	38.36	5.00e-44	171.00
IUUC-Sar-112965	Sorex araneus	76.00	0.00e+00	1575.00
IUUC-Sbi-113880	Sorghum bicolor	41.37	1.00e-44	174.00
IUUC-Sre-114954	Sporisorium reilianum	50.38	1.00e-34	141.00
IUUC-Ssc-115927	Sus scrofa	84.41	0.00e+00	5028.00
IUUC-Tgu-117132	Taeniopygia guttata	84.57	0.00e+00	7331.00
IUUC-Tru-118115	Takifugu rubripes	73.04	0.00e+00	6235.00
IUUC-Tsy-118899	Tarsius syrichta	81.28	0.00e+00	4121.00
IUUC-Tni-120891	Tetraodon nigroviridis	72.29	0.00e+00	6214.00
IUUC-Tca-121399	Theobroma cacao	44.63	4.00e-42	165.00
IUUC-Tae-125407	Triticum aestivum	47.80	2.00e-47	183.00
IUUC-Tur-126479	Triticum urartu	45.86	1.00e-41	164.00
IUUC-Tme-126930	Tuber melanosporum	41.70	2.00e-47	184.00
IUUC-Tbe-127630	Tupaia belangeri	79.44	0.00e+00	1301.00
IUUC-Ttr-128629	Tursiops truncatus	81.64	0.00e+00	7059.00
IUUC-Uma-129323	Ustilago maydis	43.86	3.00e-36	147.00
IUUC-Vpa-130310	Vicugna pacos	82.52	0.00e+00	6988.00
IUUC-Vvi-131664	Vitis vinifera	37.02	5.00e-36	145.00
IUUC-Xma-133613	Xiphophorus maculatus	74.51	0.00e+00	6334.00
IUUC-Zma-135768	Zea mays	41.59	4.00e-44	174.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence