iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068117

Ensembl Protein ID

ENSMLUP00000008295.2

UniProt Accession

G1PCY1; G1PCY1_MYOLU

Genbank Protein ID

ENSMLUP00000008295

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02033815

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000009081.2	ENSMLUT00000009104.2	ENSMLUP00000008295.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	77.55	0.00e+00	1788.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

RTPQNRVRGE VSPTMTSTGQ DSTTTRQRRS IHNPQTPPQD SSIVSKPGVK KGTGLRSSPR 60
LAEVKKKGRM KKLSQAAEQE LVQGIQVLDL TLETKTLSGT GLVFDEQLND FHCLWDDSFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCACCCCCC AGAACCGCGT CAGGGGTGAA GTCTCCCCGA CCATGACCTC CACCGGCCAG 60
GATTCCACCA CAACTAGGCA GCGAAGGAGT ATACACAACC CCCAGACGCC CCCCCAGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	42.33	2.00e-71	263.00
IUUC-Aml-002087	Ailuropoda melanoleuca	82.18	0.00e+00	1865.00
IUUC-Atr-002745	Amborella trichopoda	43.34	2.00e-84	306.00
IUUC-Aca-004303	Anolis carolinensis	58.43	0.00e+00	1011.00
IUUC-Aly-006432	Arabidopsis lyrata	42.78	4.00e-83	302.00
IUUC-Ath-007355	Arabidopsis thaliana	43.08	9.00e-88	317.00
IUUC-Ago-007972	Ashbya gossypii	36.67	7.00e-83	301.00
IUUC-Acl-008187	Aspergillus clavatus	43.89	9.00e-86	311.00
IUUC-Afl-008399	Aspergillus flavus	44.91	2.00e-48	186.00
IUUC-Afu-008954	Aspergillus fumigatus	41.82	1.00e-74	274.00
IUUC-Ani-009142	Aspergillus nidulans	43.01	2.00e-77	283.00
IUUC-Aor-010069	Aspergillus oryzae	41.69	2.00e-76	280.00
IUUC-Ate-010291	Aspergillus terreus	44.12	3.00e-84	306.00
IUUC-Ame-010780	Astyanax mexicanus	50.43	0.00e+00	785.00
IUUC-Bta-013052	Bos taurus	77.55	0.00e+00	1716.00
IUUC-Bci-013789	Botrytis cinerea	40.45	2.00e-79	290.00
IUUC-Bdi-014007	Brachypodium distachyon	42.66	1.00e-83	304.00
IUUC-Bol-015468	Brassica oleracea	43.56	3.00e-85	309.00
IUUC-Bra-016680	Brassica rapa	43.56	3.00e-85	309.00
IUUC-Cel-018220	Caenorhabditis elegans	38.20	1.00e-141	497.00
IUUC-Cja-019473	Callithrix jacchus	73.53	0.00e+00	1657.00
IUUC-Cfa-020263	Canis familiaris	81.78	0.00e+00	1821.00
IUUC-Cpo-021691	Cavia porcellus	78.62	0.00e+00	1767.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	52.42	4.00e-54	204.00
IUUC-Csa-024223	Chlorocebus sabaeus	76.66	0.00e+00	1744.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	40.31	3.00e-78	286.00
IUUC-Cne-026978	Cryptococcus neoformans	43.39	2.00e-86	313.00
IUUC-Dre-028820	Danio rerio	49.82	0.00e+00	1053.00
IUUC-Dno-029160	Dasypus novemcinctus	71.54	0.00e+00	1607.00
IUUC-Dor-030859	Dipodomys ordii	68.26	0.00e+00	1576.00
IUUC-Dse-031186	Dothistroma septosporum	40.93	7.00e-79	288.00
IUUC-Dme-031963	Drosophila melanogaster	44.58	4.00e-97	349.00
IUUC-Ete-032279	Echinops telfairi	63.72	5.00e-146	511.00
IUUC-Eca-033842	Equus caballus	82.33	0.00e+00	1862.00
IUUC-Eeu-034487	Erinaceus europaeus	76.02	2.00e-159	556.00
IUUC-Fca-036430	Felis catus	80.85	0.00e+00	1813.00
IUUC-Fox-038067	Fusarium oxysporum	40.89	5.00e-81	295.00
IUUC-Fso-038263	Fusarium solani	42.16	5.00e-82	298.00
IUUC-Ggr-040062	Gaeumannomyces graminis	43.39	1.00e-75	277.00
IUUC-Gma-043738	Glycine max	43.15	1.00e-87	317.00
IUUC-Ggo-045022	Gorilla gorilla	76.58	0.00e+00	1753.00
IUUC-Hsa-046904	Homo sapiens	76.50	0.00e+00	1748.00
IUUC-Hvu-047285	Hordeum vulgare	46.15	4.00e-86	311.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	79.21	0.00e+00	1832.00
IUUC-Kpa-049281	Komagataella pastoris	40.44	3.00e-85	310.00
IUUC-Lch-050330	Latimeria chalumnae	46.04	0.00e+00	939.00
IUUC-Lpe-051214	Leersia perrieri	40.96	7.00e-88	318.00
IUUC-Lma-053263	Leptosphaeria maculans	43.15	7.00e-88	318.00
IUUC-Laf-053386	Loxodonta africana	76.50	0.00e+00	1712.00
IUUC-Mcc-055530	Macaca mulatta	76.75	0.00e+00	1751.00
IUUC-Meu-056442	Macropus eugenii	65.94	0.00e+00	934.00
IUUC-Mor-057095	Magnaporthe oryzae	39.95	3.00e-84	306.00
IUUC-Mpo-057389	Magnaporthe poae	43.10	9.00e-76	278.00
IUUC-Mtr-058463	Medicago truncatula	45.48	8.00e-92	331.00
IUUC-Mla-059143	Melampsora laricipopulina	40.05	1.00e-79	290.00
IUUC-Mmr-060637	Microcebus murinus	78.02	0.00e+00	1839.00
IUUC-Mdo-062198	Monodelphis domestica	65.33	0.00e+00	1048.00
IUUC-Mmu-063346	Mus musculus	73.47	0.00e+00	1655.00
IUUC-Mac-064630	Musa acuminata	43.47	6.00e-83	301.00
IUUC-Mpu-065884	Mustela putorius furo	81.35	0.00e+00	1855.00
IUUC-Nfi-068404	Neosartorya fischeri	43.39	6.00e-86	312.00
IUUC-Ncr-068672	Neurospora crassa	41.52	6.00e-82	298.00
IUUC-Nle-069868	Nomascus leucogenys	91.43	0.00e+00	747.00
IUUC-Opr-071074	Ochotona princeps	66.06	0.00e+00	1038.00
IUUC-Ont-072246	Oreochromis niloticus	45.55	0.00e+00	926.00
IUUC-Oan-072911	Ornithorhynchus anatinus	67.73	2.00e-106	380.00
IUUC-Ocu-074627	Oryctolagus cuniculus	78.91	0.00e+00	1835.00
IUUC-Oba-075489	Oryza barthii	37.96	4.00e-87	315.00
IUUC-Obr-076150	Oryza brachyantha	38.95	8.00e-87	314.00
IUUC-Ogl-077437	Oryza glaberrima	44.89	2.00e-86	313.00
IUUC-Ogu-078370	Oryza glumaepatula	40.68	2.00e-87	317.00
IUUC-Oin-079210	Oryza indica	40.68	2.00e-87	316.00
IUUC-Olo-080971	Oryza longistaminata	43.50	6.00e-76	278.00
IUUC-Oni-082031	Oryza nivara	40.68	2.00e-87	316.00
IUUC-Opu-083471	Oryza punctata	39.32	4.00e-87	315.00
IUUC-Oru-084755	Oryza rufipogon	45.17	4.00e-87	315.00
IUUC-Osa-085447	Oryza sativa	45.17	4.00e-87	315.00
IUUC-Oga-089155	Otolemur garnettii	76.57	0.00e+00	1763.00
IUUC-Oar-089620	Ovis aries	77.45	0.00e+00	1735.00
IUUC-Ptr-090812	Pan troglodytes	85.45	0.00e+00	1226.00
IUUC-Pan-092340	Papio anubis	76.50	0.00e+00	1743.00
IUUC-Pma-094386	Petromyzon marinus	53.45	0.00e+00	811.00
IUUC-Pno-095131	Phaeosphaeria nodorum	45.12	4.00e-75	275.00
IUUC-Ppa-095550	Physcomitrella patens	44.69	3.00e-86	313.00
IUUC-Pfo-096110	Poecilia formosa	54.85	0.00e+00	711.00
IUUC-Pab-098422	Pongo abelii	76.22	0.00e+00	1696.00
IUUC-Pop-099174	Populus trichocarpa	41.87	3.00e-82	299.00
IUUC-Pca-100833	Procavia capensis	73.25	0.00e+00	1540.00
IUUC-Ppe-101644	Prunus persica	38.05	3.00e-88	318.00
IUUC-Pva-102410	Pteropus vampyrus	78.63	0.00e+00	1710.00
IUUC-Ptt-103841	Puccinia triticina	38.56	3.00e-79	289.00
IUUC-Pte-104383	Pyrenophora teres	42.12	8.00e-86	311.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	42.38	4.00e-86	312.00
IUUC-Rno-105131	Rattus norvegicus	73.01	0.00e+00	1648.00
IUUC-Sce-106274	Saccharomyces cerevisiae	41.01	6.00e-81	295.00
IUUC-Sha-106661	Sarcophilus harrisii	54.30	0.00e+00	802.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	42.59	2.00e-86	313.00
IUUC-Spo-108300	Schizosaccharomyces pombe	44.69	9.00e-85	308.00
IUUC-Smo-109615	Selaginella moellendorffii	47.33	9.00e-86	311.00
IUUC-Sit-110160	Setaria italica	45.04	3.00e-83	302.00
IUUC-Sly-111164	Solanum lycopersicum	38.57	2.00e-82	299.00
IUUC-Stu-112685	Solanum tuberosum	40.05	6.00e-73	268.00
IUUC-Sar-113692	Sorex araneus	66.22	0.00e+00	768.00
IUUC-Sbi-114301	Sorghum bicolor	44.92	6.00e-83	301.00
IUUC-Sre-115013	Sporisorium reilianum	42.64	2.00e-82	300.00
IUUC-Ssc-115724	Sus scrofa	79.31	0.00e+00	1725.00
IUUC-Tgu-116605	Taeniopygia guttata	53.50	7.00e-111	394.00
IUUC-Tru-117614	Takifugu rubripes	55.02	0.00e+00	860.00
IUUC-Tsy-118807	Tarsius syrichta	65.05	0.00e+00	840.00
IUUC-Tni-119809	Tetraodon nigroviridis	54.84	0.00e+00	803.00
IUUC-Tca-121312	Theobroma cacao	44.59	5.00e-86	312.00
IUUC-Tre-121930	Trichoderma reesei	42.64	4.00e-83	302.00
IUUC-Tvi-122373	Trichoderma virens	42.89	8.00e-83	301.00
IUUC-Tae-123064	Triticum aestivum	41.35	1.00e-78	286.00
IUUC-Tme-127027	Tuber melanosporum	41.96	6.00e-70	258.00
IUUC-Tbe-127675	Tupaia belangeri	53.81	7.00e-96	345.00
IUUC-Ttr-128411	Tursiops truncatus	78.25	0.00e+00	1771.00
IUUC-Uma-129408	Ustilago maydis	41.01	4.00e-75	275.00
IUUC-Vda-129994	Verticillium dahliae	39.29	2.00e-74	273.00
IUUC-Vpa-130525	Vicugna pacos	63.64	3.00e-60	226.00
IUUC-Vvi-131038	Vitis vinifera	42.54	1.00e-86	314.00
IUUC-Xtr-132618	Xenopus tropicalis	56.39	0.00e+00	956.00
IUUC-Xma-133730	Xiphophorus maculatus	48.38	0.00e+00	702.00
IUUC-Yli-134680	Yarrowia lipolytica	42.22	3.00e-82	300.00
IUUC-Zma-135110	Zea mays	45.04	3.00e-84	305.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence