iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012641

Ensembl Protein ID

ENSBTAP00000011931.4

UniProt Accession

F1MXN0; F1MXN0_BOVIN

Genbank Protein ID

ENSBTAP00000011931

Protein Name

E3 ubiquitin-protein ligase RNF144B

Genbank Nucleotide ID

DAAA02055608

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000009055.4	ENSBTAT00000011931.4	ENSBTAP00000011931.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	4.90e-50	170.8	31	223

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i+eg+ + i+cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+++
   Q: 31   CKLCLCEQSLDKMTTLQECRCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHgtLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPCR 119
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + + vec++c+ +fC++Ck++wH+++sC++ +     te   + +   + ++a +k+Cp C+vyie+neg
   Q: 120  TWCPVADCQTVCPVATSDpgQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPGILPTE---HGTLFGTETDAPIKQCPVCRVYIERNEG 206
           ************99988777899999***************************999999...88999999******************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 207  CAQMMCKNCKHTFCWYC 223
           ***************** PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MGSVGRLHCL TMTAAENPTP GDLALAPLVT CKLCLCEQSL DKMTTLQECR CIFCTACLKQ 60
YMQLAIREGC GSPITCPDMV CLNHGTLQEA EIACLVPVDQ FQLYQRLKFE REVHLDPCRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGCTGCTG CTGCTGCTGC TGCTGGCGGT GCTGCGCCCC GCGCTCTGAG AGGTTCCCCG 60
GGCAGCGCAG CTGCACCCCG AGGCAGGAGG CGGTTCGAGG GACTCCTCCT CCCTCTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	92.43	4.00e-165	573.00
IUUC-Atr-002709	Amborella trichopoda	27.14	2.00e-15	78.20
IUUC-Apl-004112	Anas platyrhynchos	82.27	1.00e-129	455.00
IUUC-Aca-004533	Anolis carolinensis	77.05	1.00e-137	482.00
IUUC-Bra-018037	Brassica rapa	27.40	3.00e-12	66.60
IUUC-Cja-019626	Callithrix jacchus	78.29	8.00e-136	476.00
IUUC-Cfa-020702	Canis familiaris	92.76	6.00e-167	579.00
IUUC-Cpo-022147	Cavia porcellus	95.07	4.00e-170	590.00
IUUC-Csa-023473	Chlorocebus sabaeus	93.75	1.00e-168	585.00
IUUC-Cho-024298	Choloepus hoffmanni	90.31	1.00e-138	485.00
IUUC-Dre-028099	Danio rerio	64.29	2.00e-90	325.00
IUUC-Dno-029122	Dasypus novemcinctus	87.87	6.00e-155	540.00
IUUC-Dor-030669	Dipodomys ordii	94.85	5.00e-131	459.00
IUUC-Ete-033141	Echinops telfairi	80.92	3.00e-130	457.00
IUUC-Eca-034360	Equus caballus	94.41	2.00e-169	587.00
IUUC-Eeu-034538	Erinaceus europaeus	71.83	2.00e-84	304.00
IUUC-Fca-036055	Felis catus	92.11	1.00e-165	575.00
IUUC-Fal-037339	Ficedula albicollis	82.14	3.00e-133	467.00
IUUC-Gmo-038780	Gadus morhua	60.29	8.00e-84	303.00
IUUC-Gga-040256	Gallus gallus	80.14	3.00e-132	464.00
IUUC-Gac-042127	Gasterosteus aculeatus	61.64	2.00e-92	332.00
IUUC-Ggo-044867	Gorilla gorilla	94.74	1.00e-169	588.00
IUUC-Hsa-046928	Homo sapiens	94.41	3.00e-169	587.00
IUUC-Hvu-047484	Hordeum vulgare	30.00	5.00e-17	82.00
IUUC-Itr-048250	Ictidomys tridecemlineatus	94.30	7.00e-107	379.00
IUUC-Lch-050168	Latimeria chalumnae	73.20	1.00e-129	455.00
IUUC-Lpe-051649	Leersia perrieri	29.06	1.00e-15	79.00
IUUC-Loc-052150	Lepisosteus oculatus	60.93	6.00e-88	317.00
IUUC-Laf-053967	Loxodonta africana	93.42	8.00e-167	579.00
IUUC-Mcc-055898	Macaca mulatta	93.75	1.00e-168	585.00
IUUC-Meu-056628	Macropus eugenii	91.03	3.00e-41	161.00
IUUC-Mtr-057989	Medicago truncatula	26.76	6.00e-19	87.80
IUUC-Mga-059820	Meleagris gallopavo	79.08	1.00e-130	459.00
IUUC-Mmr-060680	Microcebus murinus	93.09	5.00e-167	579.00
IUUC-Mdo-062839	Monodelphis domestica	84.59	1.00e-151	528.00
IUUC-Mmu-063339	Mus musculus	87.50	6.00e-147	513.00
IUUC-Mac-065414	Musa acuminata	29.38	2.00e-19	90.10
IUUC-Mpu-065973	Mustela putorius furo	90.79	8.00e-163	566.00
IUUC-Mlu-067112	Myotis lucifugus	93.75	1.00e-159	555.00
IUUC-Nle-069795	Nomascus leucogenys	94.08	2.00e-169	587.00
IUUC-Opr-070390	Ochotona princeps	87.50	6.00e-151	526.00
IUUC-Ont-072329	Oreochromis niloticus	63.95	2.00e-88	318.00
IUUC-Oan-072980	Ornithorhynchus anatinus	83.33	1.00e-136	479.00
IUUC-Ocu-073845	Oryctolagus cuniculus	93.75	1.00e-168	585.00
IUUC-Ola-086872	Oryzias latipes	61.80	2.00e-84	305.00
IUUC-Oga-088954	Otolemur garnettii	93.42	2.00e-166	577.00
IUUC-Oar-089879	Ovis aries	99.34	6.00e-179	619.00
IUUC-Ptr-090685	Pan troglodytes	94.41	3.00e-169	587.00
IUUC-Pan-092086	Papio anubis	93.42	1.00e-168	585.00
IUUC-Psi-093481	Pelodiscus sinensis	81.25	2.00e-138	484.00
IUUC-Pfo-096065	Poecilia formosa	62.06	8.00e-91	326.00
IUUC-Pab-098031	Pongo abelii	94.08	1.00e-168	585.00
IUUC-Pop-099816	Populus trichocarpa	26.39	3.00e-15	75.90
IUUC-Pca-100936	Procavia capensis	92.76	1.00e-164	572.00
IUUC-Pva-102864	Pteropus vampyrus	83.55	3.00e-145	507.00
IUUC-Rno-105503	Rattus norvegicus	87.50	1.00e-146	511.00
IUUC-Sha-107425	Sarcophilus harrisii	83.93	1.00e-150	525.00
IUUC-Stu-112736	Solanum tuberosum	27.15	3.00e-17	82.00
IUUC-Sbi-114532	Sorghum bicolor	28.23	2.00e-14	72.80
IUUC-Ssc-115458	Sus scrofa	94.79	6.00e-161	559.00
IUUC-Tgu-117226	Taeniopygia guttata	81.07	6.00e-133	466.00
IUUC-Tru-118362	Takifugu rubripes	64.29	1.00e-92	332.00
IUUC-Tsy-119255	Tarsius syrichta	95.07	8.00e-172	595.00
IUUC-Tni-120140	Tetraodon nigroviridis	62.45	7.00e-89	320.00
IUUC-Tae-124420	Triticum aestivum	31.22	2.00e-17	84.00
IUUC-Tbe-127306	Tupaia belangeri	94.74	4.00e-169	587.00
IUUC-Ttr-128923	Tursiops truncatus	95.07	2.00e-161	560.00
IUUC-Vpa-130148	Vicugna pacos	94.74	3.00e-169	587.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence