iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049539

Ensembl Protein ID

ENSLACP00000021466.1

UniProt Accession

H3BHU5; H3BHU5_LATCH

Genbank Protein ID

ENSLACP00000021466

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01008183

Gene Name

WDR5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000018863.1	ENSLACT00000021607.1	ENSLACP00000021466.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.60e-59	193.4	127	166
UBD/Beta-Prp	1.10e-88	297.5	40	332

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH++ v+c++f +  +l+vsGs D ++++WD++tg++lk+
   Q: 127  GHSNYVFCCNFnPQsNLIVSGSFDESVRIWDVKTGKCLKT 166
           8***********666**********************986 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           tl gh k+v + vkfsp++++la++s+d+ ik+w + +gk+ +++sgh+ ++++v +s+d+++lv++s+D+t+k+wd+s+gkc+ tlkg
   Q: 40   TLAGHTKAVSS-VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKG 127
           67777776666.***************************************************************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h+++v +++f+p+++ +vsGs d+ +r+wd++tg+cl+ tl  h++ v+ v+++ dg+l+vs+s+D+ +r+Wd ++g++l+tl  ++++
   Q: 128  HSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK-TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP 215
           **************************************.********************************************999*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs...pnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +v  ++f++ngk+++++ ld+t+klwd+++g+c++t++gh++  +++ +      ++++vsgs+D+ ++iW+l++++++++lq+h + v
   Q: 216  PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANfsvTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVV 304
           **********************************************98887899*********************************** PP
   S: 268  isvavlsfgdnvlvlgse..dskvniwkl 294
           is a+ ++++n++++++   d+++++wk 
   Q: 305  ISTAC-HPTENIIASAALenDKTIKLWKS 332
           *****.*******9998888*******96 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MATEEKKPET EATKTQSTPS SSANQSKPVP VKPNYTLKFT LAGHTKAVSS VKFSPNGEWL 60
ASSSADKLIK IWGAYDGKFE KTISGHKLGI SDVAWSSDSN LLVSASDDKT LKIWDVSSGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNAGGGGT CTGGATGGGA ACCTCCTTTC CCCAGCTCTG 60
AAGAAGCTCC CGGTGAGACG GCGGATTCTT CCCCCCCACC GCCCGGAGCC CAAGGCAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

lcm:102363163

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000502	Aegilops tauschii	53.02	5.00e-90	323.00
IUUC-Aml-002420	Ailuropoda melanoleuca	98.75	0.00e+00	642.00
IUUC-Atr-002439	Amborella trichopoda	69.51	3.00e-130	457.00
IUUC-Apl-003436	Anas platyrhynchos	91.02	4.00e-168	583.00
IUUC-Aca-004259	Anolis carolinensis	97.31	0.00e+00	636.00
IUUC-Aly-005723	Arabidopsis lyrata	62.42	3.00e-117	414.00
IUUC-Ath-007308	Arabidopsis thaliana	65.45	5.00e-117	413.00
IUUC-Ago-007915	Ashbya gossypii	37.58	2.00e-45	176.00
IUUC-Acl-008045	Aspergillus clavatus	45.95	8.00e-84	304.00
IUUC-Afl-008596	Aspergillus flavus	44.66	7.00e-81	294.00
IUUC-Afu-009074	Aspergillus fumigatus	46.75	1.00e-83	303.00
IUUC-Ani-009318	Aspergillus nidulans	50.00	3.00e-83	302.00
IUUC-Ang-009775	Aspergillus niger	45.63	3.00e-83	302.00
IUUC-Aor-010222	Aspergillus oryzae	44.66	5.00e-81	295.00
IUUC-Ate-010583	Aspergillus terreus	48.75	4.00e-81	295.00
IUUC-Ame-011349	Astyanax mexicanus	99.34	2.00e-179	621.00
IUUC-Bgr-011968	Blumeria graminis	50.33	9.00e-85	307.00
IUUC-Bta-013016	Bos taurus	99.03	1.00e-180	625.00
IUUC-Bci-013948	Botrytis cinerea	49.84	8.00e-86	310.00
IUUC-Bdi-014263	Brachypodium distachyon	62.13	2.00e-120	424.00
IUUC-Bol-015900	Brassica oleracea	62.50	9.00e-114	402.00
IUUC-Bra-017143	Brassica rapa	62.17	8.00e-115	406.00
IUUC-Cel-018355	Caenorhabditis elegans	72.24	3.00e-132	464.00
IUUC-Cja-019936	Callithrix jacchus	98.75	0.00e+00	642.00
IUUC-Cfa-020596	Canis familiaris	98.75	0.00e+00	642.00
IUUC-Cpo-021318	Cavia porcellus	98.75	0.00e+00	642.00
IUUC-Cre-022935	Chlamydomonas reinhardtii	47.62	3.00e-80	291.00
IUUC-Csa-023053	Chlorocebus sabaeus	98.75	0.00e+00	642.00
IUUC-Cho-024642	Choloepus hoffmanni	83.78	6.00e-156	543.00
IUUC-Cin-025495	Ciona intestinalis	90.26	1.00e-168	585.00
IUUC-Csv-025988	Ciona savignyi	91.86	4.00e-164	570.00
IUUC-Cne-027025	Cryptococcus neoformans	32.13	3.00e-53	202.00
IUUC-Cme-027119	Cyanidioschyzon merolae	51.80	6.00e-105	373.00
IUUC-Dre-027521	Danio rerio	96.71	0.00e+00	634.00
IUUC-Dno-029739	Dasypus novemcinctus	99.67	2.00e-178	618.00
IUUC-Dor-030966	Dipodomys ordii	99.35	2.00e-180	624.00
IUUC-Dse-031189	Dothistroma septosporum	48.91	4.00e-86	311.00
IUUC-Dme-031613	Drosophila melanogaster	95.05	8.00e-173	599.00
IUUC-Ete-033098	Echinops telfairi	81.47	1.00e-154	538.00
IUUC-Eca-033790	Equus caballus	98.75	0.00e+00	642.00
IUUC-Eeu-034805	Erinaceus europaeus	82.28	4.00e-152	530.00
IUUC-Fca-035901	Felis catus	98.75	0.00e+00	642.00
IUUC-Fal-037413	Ficedula albicollis	98.20	0.00e+00	637.00
IUUC-Fox-037876	Fusarium oxysporum	46.45	2.00e-58	218.00
IUUC-Gmo-039131	Gadus morhua	93.71	4.00e-179	620.00
IUUC-Ggr-040071	Gaeumannomyces graminis	40.27	9.00e-65	241.00
IUUC-Gga-040789	Gallus gallus	98.20	0.00e+00	637.00
IUUC-Gac-042634	Gasterosteus aculeatus	94.61	1.00e-177	614.00
IUUC-Gma-043692	Glycine max	66.67	6.00e-128	450.00
IUUC-Ggo-044443	Gorilla gorilla	98.75	0.00e+00	642.00
IUUC-Hsa-046290	Homo sapiens	98.75	0.00e+00	642.00
IUUC-Hvu-047077	Hordeum vulgare	56.82	6.00e-79	286.00
IUUC-Itr-048954	Ictidomys tridecemlineatus	98.75	0.00e+00	642.00
IUUC-Kpa-049404	Komagataella pastoris	45.42	1.00e-65	243.00
IUUC-Lpe-051082	Leersia perrieri	61.33	4.00e-119	420.00
IUUC-Loc-051743	Lepisosteus oculatus	99.34	2.00e-179	621.00
IUUC-Lma-053188	Leptosphaeria maculans	46.73	8.00e-86	310.00
IUUC-Laf-054432	Loxodonta africana	94.03	0.00e+00	631.00
IUUC-Mcc-055603	Macaca mulatta	98.75	0.00e+00	642.00
IUUC-Meu-056440	Macropus eugenii	92.46	7.00e-157	546.00
IUUC-Mor-056965	Magnaporthe oryzae	36.71	3.00e-69	255.00
IUUC-Mpo-057333	Magnaporthe poae	41.16	2.00e-61	230.00
IUUC-Mtr-057951	Medicago truncatula	65.91	5.00e-123	433.00
IUUC-Mla-058896	Melampsora laricipopulina	43.90	1.00e-72	266.00
IUUC-Mga-060046	Meleagris gallopavo	97.90	0.00e+00	637.00
IUUC-Mvi-060453	Microbotryum violaceum	46.49	9.00e-89	320.00
IUUC-Mmr-061020	Microcebus murinus	91.32	2.00e-175	607.00
IUUC-Mdo-062204	Monodelphis domestica	95.92	0.00e+00	630.00
IUUC-Mmu-063917	Mus musculus	98.75	0.00e+00	642.00
IUUC-Mac-065310	Musa acuminata	66.22	1.00e-122	432.00
IUUC-Mpu-066072	Mustela putorius furo	98.75	0.00e+00	642.00
IUUC-Mlu-068209	Myotis lucifugus	98.75	0.00e+00	642.00
IUUC-Nfi-068538	Neosartorya fischeri	46.43	6.00e-83	301.00
IUUC-Ncr-068651	Neurospora crassa	41.96	9.00e-73	267.00
IUUC-Nle-069383	Nomascus leucogenys	88.20	7.00e-154	536.00
IUUC-Opr-070937	Ochotona princeps	83.96	4.00e-143	500.00
IUUC-Ont-071458	Oreochromis niloticus	95.51	1.00e-179	622.00
IUUC-Oan-073597	Ornithorhynchus anatinus	99.67	1.00e-179	621.00
IUUC-Oba-075292	Oryza barthii	56.42	2.00e-99	355.00
IUUC-Obr-076723	Oryza brachyantha	54.90	8.00e-97	346.00
IUUC-Ogl-077251	Oryza glaberrima	60.06	8.00e-117	412.00
IUUC-Ogu-078882	Oryza glumaepatula	49.58	6.00e-103	367.00
IUUC-Oin-079601	Oryza indica	54.25	4.00e-112	397.00
IUUC-Olo-080976	Oryza longistaminata	62.95	9.00e-103	365.00
IUUC-Ome-081430	Oryza meridionalis	60.46	5.00e-117	413.00
IUUC-Oni-082182	Oryza nivara	49.18	2.00e-102	365.00
IUUC-Opu-083880	Oryza punctata	59.80	4.00e-116	410.00
IUUC-Oru-084935	Oryza rufipogon	53.65	7.00e-99	353.00
IUUC-Osa-085706	Oryza sativa	60.06	8.00e-117	412.00
IUUC-Ola-087134	Oryzias latipes	94.91	8.00e-180	622.00
IUUC-Olu-087660	Ostreococcus lucimarinus	42.50	2.00e-40	157.00
IUUC-Oga-088672	Otolemur garnettii	97.60	0.00e+00	640.00
IUUC-Oar-089860	Ovis aries	86.21	6.00e-157	546.00
IUUC-Ptr-091513	Pan troglodytes	98.75	0.00e+00	642.00
IUUC-Pan-092046	Papio anubis	98.75	0.00e+00	642.00
IUUC-Psi-093192	Pelodiscus sinensis	97.90	0.00e+00	637.00
IUUC-Pno-094881	Phaeosphaeria nodorum	48.04	6.00e-90	324.00
IUUC-Ppa-095367	Physcomitrella patens	72.58	5.00e-134	470.00
IUUC-Pfo-097434	Poecilia formosa	95.21	3.00e-179	620.00
IUUC-Pab-098758	Pongo abelii	87.87	3.00e-154	537.00
IUUC-Pop-099778	Populus trichocarpa	64.87	7.00e-122	429.00
IUUC-Pca-100281	Procavia capensis	77.97	8.00e-123	432.00
IUUC-Ppe-101341	Prunus persica	66.03	2.00e-123	434.00
IUUC-Pva-103020	Pteropus vampyrus	98.12	0.00e+00	640.00
IUUC-Pgr-103589	Puccinia graminis	39.83	5.00e-70	258.00
IUUC-Ptt-103745	Puccinia triticina	34.67	9.00e-37	147.00
IUUC-Pte-104153	Pyrenophora teres	51.43	9.00e-94	337.00
IUUC-Pyt-104712	Pyrenophora triticirepentis	52.06	1.00e-78	286.00
IUUC-Rno-105858	Rattus norvegicus	98.75	0.00e+00	642.00
IUUC-Sce-106243	Saccharomyces cerevisiae	34.78	1.00e-39	156.00
IUUC-Sha-107101	Sarcophilus harrisii	98.75	0.00e+00	644.00
IUUC-Sja-107858	Schizosaccharomyces japonicus	51.17	1.00e-68	253.00
IUUC-Spo-108117	Schizosaccharomyces pombe	47.98	5.00e-64	238.00
IUUC-Smo-109155	Selaginella moellendorffii	70.97	4.00e-132	463.00
IUUC-Sit-110688	Setaria italica	62.00	2.00e-119	421.00
IUUC-Sly-110891	Solanum lycopersicum	65.71	1.00e-126	445.00
IUUC-Stu-112365	Solanum tuberosum	65.71	5.00e-127	446.00
IUUC-Sbi-114284	Sorghum bicolor	62.00	1.00e-118	418.00
IUUC-Sre-115180	Sporisorium reilianum	42.57	1.00e-66	246.00
IUUC-Ssc-116204	Sus scrofa	99.67	1.00e-178	618.00
IUUC-Tgu-117172	Taeniopygia guttata	98.20	0.00e+00	637.00
IUUC-Tru-118320	Takifugu rubripes	91.62	3.00e-178	617.00
IUUC-Tni-120660	Tetraodon nigroviridis	92.79	4.00e-110	390.00
IUUC-Tca-121051	Theobroma cacao	67.86	9.00e-126	442.00
IUUC-Tre-122237	Trichoderma reesei	44.75	8.00e-85	307.00
IUUC-Tvi-122635	Trichoderma virens	46.18	3.00e-85	308.00
IUUC-Tae-123971	Triticum aestivum	59.62	4.00e-120	424.00
IUUC-Tur-126217	Triticum urartu	55.84	1.00e-76	278.00
IUUC-Tme-127061	Tuber melanosporum	59.87	9.00e-112	396.00
IUUC-Tbe-127488	Tupaia belangeri	87.22	9.00e-157	545.00
IUUC-Ttr-129309	Tursiops truncatus	92.79	2.00e-171	594.00
IUUC-Uma-129585	Ustilago maydis	41.64	1.00e-73	270.00
IUUC-Vda-129907	Verticillium dahliae	44.71	4.00e-79	288.00
IUUC-Vpa-130384	Vicugna pacos	84.98	1.00e-159	555.00
IUUC-Vvi-131269	Vitis vinifera	66.45	2.00e-119	421.00
IUUC-Xtr-131945	Xenopus tropicalis	98.50	0.00e+00	640.00
IUUC-Xma-132997	Xiphophorus maculatus	95.21	3.00e-179	620.00
IUUC-Yli-134418	Yarrowia lipolytica	42.95	1.00e-75	276.00
IUUC-Zma-135765	Zea mays	61.67	2.00e-117	415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence