iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035447

Ensembl Protein ID

ENSFCAP00000016674.1

UniProt Accession

M3WQP3; M3WQP3_FELCA

Genbank Protein ID

ENSFCAP00000016674

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02094651

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000023401.1	ENSFCAT00000025360.1	ENSFCAP00000016674.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	9.80e-19	67.0	13	47

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGnp+++g+CSkC+ree++++r
   Q: 13   DQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKAR 47
           79*******************************86 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MSLKSERRGI HVDQSELLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ IQEDWELAER 60
LQREEEEAFA SSQSSQGAQS LTFSKFEKKT NEKTRKVTTV KKFFSASSRV GSKKEIQEAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGAAGATG AGCCTGAAGT CTGAACGCCG TGGAATTCAC GTGGATCAGT CGGAGCTCCT 60
ATGCAAGAAA GGATGTGGTT ACTATGGCAA CCCTGCTTGG CAGGGTTTCT GCTCCAAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0003677--F:DNA binding
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	32.26	3.00e-20	93.20
IUUC-Aml-001771	Ailuropoda melanoleuca	88.92	0.00e+00	757.00
IUUC-Atr-003154	Amborella trichopoda	36.52	6.00e-23	101.00
IUUC-Apl-004018	Anas platyrhynchos	89.02	0.00e+00	838.00
IUUC-Aca-005227	Anolis carolinensis	23.47	1.00e-09	58.50
IUUC-Aly-006138	Arabidopsis lyrata	35.45	7.00e-25	108.00
IUUC-Ath-006747	Arabidopsis thaliana	34.92	1.00e-24	107.00
IUUC-Ago-007776	Ashbya gossypii	29.05	3.00e-23	102.00
IUUC-Acl-008235	Aspergillus clavatus	31.45	1.00e-29	124.00
IUUC-Afl-008570	Aspergillus flavus	32.21	4.00e-32	133.00
IUUC-Afu-008815	Aspergillus fumigatus	31.23	3.00e-30	126.00
IUUC-Ani-009381	Aspergillus nidulans	30.74	2.00e-30	127.00
IUUC-Ang-009615	Aspergillus niger	30.90	3.00e-32	133.00
IUUC-Aor-010195	Aspergillus oryzae	32.21	8.00e-33	134.00
IUUC-Ate-010514	Aspergillus terreus	31.80	8.00e-31	128.00
IUUC-Ame-011365	Astyanax mexicanus	66.53	0.00e+00	668.00
IUUC-Bgr-012102	Blumeria graminis	29.07	1.00e-30	128.00
IUUC-Bta-013124	Bos taurus	95.11	0.00e+00	885.00
IUUC-Bci-013943	Botrytis cinerea	30.85	8.00e-31	129.00
IUUC-Bdi-014539	Brachypodium distachyon	34.70	5.00e-26	112.00
IUUC-Bol-016580	Brassica oleracea	35.14	8.00e-30	124.00
IUUC-Bra-017843	Brassica rapa	34.68	1.00e-29	124.00
IUUC-Cel-018199	Caenorhabditis elegans	34.36	1.00e-58	220.00
IUUC-Cja-019941	Callithrix jacchus	93.69	0.00e+00	872.00
IUUC-Cfa-020845	Canis familiaris	95.43	0.00e+00	816.00
IUUC-Cpo-022037	Cavia porcellus	93.08	0.00e+00	864.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	31.82	1.00e-20	94.70
IUUC-Csa-023272	Chlorocebus sabaeus	92.87	0.00e+00	866.00
IUUC-Cho-025076	Choloepus hoffmanni	82.48	0.00e+00	738.00
IUUC-Cin-025400	Ciona intestinalis	44.31	6.00e-113	400.00
IUUC-Csv-025941	Ciona savignyi	37.70	3.00e-87	315.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	28.72	6.00e-27	115.00
IUUC-Cne-027057	Cryptococcus neoformans	32.09	4.00e-35	142.00
IUUC-Dre-028484	Danio rerio	70.30	0.00e+00	674.00
IUUC-Dno-028906	Dasypus novemcinctus	93.70	0.00e+00	861.00
IUUC-Dor-030124	Dipodomys ordii	83.27	0.00e+00	744.00
IUUC-Dse-031437	Dothistroma septosporum	28.67	9.00e-27	115.00
IUUC-Dme-031696	Drosophila melanogaster	33.26	4.00e-68	252.00
IUUC-Ete-032573	Echinops telfairi	91.73	0.00e+00	715.00
IUUC-Eca-033711	Equus caballus	95.11	0.00e+00	886.00
IUUC-Eeu-034459	Erinaceus europaeus	73.79	8.00e-79	288.00
IUUC-Fal-036605	Ficedula albicollis	85.63	0.00e+00	777.00
IUUC-Fox-037967	Fusarium oxysporum	25.99	3.00e-17	83.60
IUUC-Fso-038110	Fusarium solani	29.33	8.00e-29	122.00
IUUC-Gmo-038785	Gadus morhua	66.40	0.00e+00	667.00
IUUC-Ggr-039760	Gaeumannomyces graminis	29.96	5.00e-26	112.00
IUUC-Gga-040584	Gallus gallus	89.63	0.00e+00	842.00
IUUC-Gac-042469	Gasterosteus aculeatus	63.78	2.00e-164	572.00
IUUC-Gma-044237	Glycine max	37.43	4.00e-26	112.00
IUUC-Ggo-044498	Gorilla gorilla	79.67	0.00e+00	719.00
IUUC-Hsa-046625	Homo sapiens	93.69	0.00e+00	872.00
IUUC-Hvu-047155	Hordeum vulgare	38.20	3.00e-26	112.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	94.91	0.00e+00	866.00
IUUC-Kpa-049160	Komagataella pastoris	29.73	1.00e-24	108.00
IUUC-Lch-050529	Latimeria chalumnae	78.50	0.00e+00	847.00
IUUC-Lpe-051024	Leersia perrieri	35.16	2.00e-28	120.00
IUUC-Loc-052644	Lepisosteus oculatus	68.34	0.00e+00	659.00
IUUC-Lma-053102	Leptosphaeria maculans	30.65	6.00e-28	119.00
IUUC-Laf-054337	Loxodonta africana	92.26	0.00e+00	867.00
IUUC-Mcc-055659	Macaca mulatta	92.01	2.00e-175	608.00
IUUC-Meu-056084	Macropus eugenii	76.47	4.00e-94	338.00
IUUC-Mor-057255	Magnaporthe oryzae	29.24	1.00e-26	115.00
IUUC-Mpo-057454	Magnaporthe poae	29.96	8.00e-28	118.00
IUUC-Mtr-058098	Medicago truncatula	35.00	1.00e-30	127.00
IUUC-Mla-059068	Melampsora laricipopulina	30.14	3.00e-31	129.00
IUUC-Mga-059624	Meleagris gallopavo	76.43	0.00e+00	832.00
IUUC-Mvi-060282	Microbotryum violaceum	49.11	5.00e-21	96.70
IUUC-Mmr-061142	Microcebus murinus	94.30	0.00e+00	884.00
IUUC-Mdo-062289	Monodelphis domestica	93.08	0.00e+00	892.00
IUUC-Mmu-063961	Mus musculus	93.08	0.00e+00	866.00
IUUC-Mac-065188	Musa acuminata	36.31	2.00e-22	100.00
IUUC-Mpu-066291	Mustela putorius furo	94.31	0.00e+00	879.00
IUUC-Mlu-067431	Myotis lucifugus	90.24	0.00e+00	837.00
IUUC-Nfi-068422	Neosartorya fischeri	31.10	5.00e-31	129.00
IUUC-Ncr-068843	Neurospora crassa	30.25	2.00e-29	124.00
IUUC-Nle-069079	Nomascus leucogenys	93.48	0.00e+00	869.00
IUUC-Opr-070790	Ochotona princeps	94.44	6.00e-57	215.00
IUUC-Ont-071789	Oreochromis niloticus	67.30	1.00e-175	608.00
IUUC-Oan-072946	Ornithorhynchus anatinus	86.82	0.00e+00	805.00
IUUC-Ocu-073816	Oryctolagus cuniculus	94.31	0.00e+00	872.00
IUUC-Oba-075738	Oryza barthii	33.71	8.00e-18	85.10
IUUC-Obr-076355	Oryza brachyantha	38.33	3.00e-27	116.00
IUUC-Ogl-077217	Oryza glaberrima	37.16	2.00e-24	107.00
IUUC-Ogu-078197	Oryza glumaepatula	28.35	9.00e-27	114.00
IUUC-Oin-080047	Oryza indica	38.20	5.00e-26	112.00
IUUC-Olo-080317	Oryza longistaminata	28.35	1.00e-26	113.00
IUUC-Ome-081589	Oryza meridionalis	37.64	8.00e-26	112.00
IUUC-Oni-082700	Oryza nivara	33.71	6.00e-18	85.10
IUUC-Opu-083923	Oryza punctata	34.36	3.00e-21	95.50
IUUC-Oru-084318	Oryza rufipogon	33.71	6.00e-18	85.10
IUUC-Osa-086246	Oryza sativa	38.98	6.00e-06	41.60
IUUC-Ola-086730	Oryzias latipes	53.15	7.00e-148	517.00
IUUC-Olu-087719	Ostreococcus lucimarinus	34.46	9.00e-24	104.00
IUUC-Oga-088992	Otolemur garnettii	82.39	0.00e+00	877.00
IUUC-Oar-089789	Ovis aries	94.52	0.00e+00	875.00
IUUC-Ptr-091636	Pan troglodytes	93.69	0.00e+00	870.00
IUUC-Pan-092911	Papio anubis	93.08	0.00e+00	868.00
IUUC-Psi-093194	Pelodiscus sinensis	76.87	0.00e+00	832.00
IUUC-Pma-094212	Petromyzon marinus	48.09	1.00e-113	402.00
IUUC-Pno-094831	Phaeosphaeria nodorum	30.25	3.00e-28	120.00
IUUC-Ppa-095705	Physcomitrella patens	33.86	5.00e-29	122.00
IUUC-Pfo-096694	Poecilia formosa	62.25	1.00e-178	619.00
IUUC-Pab-097706	Pongo abelii	93.48	0.00e+00	870.00
IUUC-Pop-099891	Populus trichocarpa	32.84	3.00e-26	112.00
IUUC-Pca-100879	Procavia capensis	87.32	4.00e-91	327.00
IUUC-Ppe-101334	Prunus persica	33.48	3.00e-26	112.00
IUUC-Pva-103225	Pteropus vampyrus	78.99	0.00e+00	708.00
IUUC-Pgr-103564	Puccinia graminis	30.38	4.00e-31	129.00
IUUC-Ptt-103802	Puccinia triticina	29.80	5.00e-26	112.00
IUUC-Pte-104345	Pyrenophora teres	29.52	4.00e-28	119.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	30.60	1.00e-28	121.00
IUUC-Rno-106101	Rattus norvegicus	92.87	0.00e+00	867.00
IUUC-Sce-106460	Saccharomyces cerevisiae	30.77	4.00e-25	109.00
IUUC-Sha-106919	Sarcophilus harrisii	78.80	0.00e+00	840.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	32.52	1.00e-30	127.00
IUUC-Spo-108087	Schizosaccharomyces pombe	30.23	8.00e-28	118.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	24.89	7.00e-07	49.30
IUUC-Smo-109411	Selaginella moellendorffii	37.14	8.00e-29	121.00
IUUC-Sit-110678	Setaria italica	37.64	4.00e-26	112.00
IUUC-Sly-111526	Solanum lycopersicum	37.85	1.00e-25	110.00
IUUC-Stu-112494	Solanum tuberosum	36.93	3.00e-26	112.00
IUUC-Sar-112929	Sorex araneus	98.55	1.00e-163	570.00
IUUC-Sbi-114242	Sorghum bicolor	32.55	1.00e-27	117.00
IUUC-Sre-115224	Sporisorium reilianum	31.43	9.00e-30	125.00
IUUC-Ssc-115239	Sus scrofa	94.72	0.00e+00	880.00
IUUC-Tgu-117499	Taeniopygia guttata	87.37	0.00e+00	820.00
IUUC-Tru-118450	Takifugu rubripes	57.89	8.00e-167	580.00
IUUC-Tsy-119462	Tarsius syrichta	93.91	0.00e+00	854.00
IUUC-Tni-120855	Tetraodon nigroviridis	63.15	3.00e-172	598.00
IUUC-Tca-121213	Theobroma cacao	35.45	4.00e-25	108.00
IUUC-Tre-122186	Trichoderma reesei	29.51	7.00e-28	118.00
IUUC-Tvi-122541	Trichoderma virens	27.40	2.00e-28	120.00
IUUC-Tae-123631	Triticum aestivum	34.51	5.00e-27	115.00
IUUC-Tur-126572	Triticum urartu	39.33	2.00e-26	113.00
IUUC-Tme-127023	Tuber melanosporum	32.93	3.00e-32	133.00
IUUC-Tbe-127453	Tupaia belangeri	97.40	0.00e+00	776.00
IUUC-Ttr-128526	Tursiops truncatus	94.70	0.00e+00	882.00
IUUC-Uma-129660	Ustilago maydis	31.78	5.00e-30	126.00
IUUC-Vda-129737	Verticillium dahliae	29.49	4.00e-24	106.00
IUUC-Vpa-130505	Vicugna pacos	91.43	0.00e+00	716.00
IUUC-Vvi-131088	Vitis vinifera	37.08	4.00e-24	105.00
IUUC-Xtr-132799	Xenopus tropicalis	77.85	0.00e+00	745.00
IUUC-Xma-133345	Xiphophorus maculatus	62.87	2.00e-174	605.00
IUUC-Yli-134416	Yarrowia lipolytica	32.85	2.00e-32	133.00
IUUC-Zma-134750	Zea mays	38.20	5.00e-26	112.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence