iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-131989

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 21

Genbank Nucleotide ID

AAMC01125261

Gene Name

usp21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000017669.3	ENSXETT00000038347.3	ENSXETP00000038347.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.20e-67	227.3	261	548

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 50   lkslqklfeelw.kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk............eknkpkeeeeeedkse 125
           l+++++++++lw  +   a +p +l+++++k+ ++f+gy+qqDaqEfl+f++d+++ e+++            ++    e         
   Q: 261  LSAFADVIASLWsPDPPDAANPARLKAVFQKYVPSFTGYSQQDAQEFLKFFMDRIHVEINRkgrktpsilsdaKRPAALE--------- 340
           57899*******777788*****************************************997776666664433333333......... PP
   S: 126  lsde............aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeeleg 202
              +             +++  ++++s i+dlF gqlks +kc++c+ +s ++e f+dlslp+p+  +       d + s ++++ l  
   Q: 341  ---HqdslsdderanqMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSPTFEVFCDLSLPIPKGLTP-GGVACDGIGSCHTNCLLSP 425
           ...22333333455559***********************************************87754.44556899*********98 PP
   S: 203  enkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGsl 290
           +    c++c+++++++kkl+++++P++L+lhL+Rf  s ++ s +k++ +v+fpl+ L l++f ++++     + +Y+L+a ++HsGs+
   Q: 426  S--QICDRCRQRTRSTKKLTIQRFPRILVLHLNRF--STTRFSIKKCSVSVDFPLHrLHLKEFASEKSG----NPTYNLYALCNHSGSV 506
           5..59******************************..77789*************99********9554....78************** PP
   S: 291  ssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           + GHY+ay++  + +W+ ++Ds+V++++e++v++   +++YvlfY+
   Q: 507  HYGHYTAYCRT-QSSWYAYNDSRVSPINESQVQS---NEGYVLFYE 548
           ***********.888*******************...********8 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MPQVCESRLA RGRELSTVGA QPKGVGKALS SHRTVSTERQ SNGVPSTPKM RPLPPRPAPA 60
DEKGKVDRGR SSQWAESSRP SSGKRGPIKG DHLLRVTNSA KGTAPPPGGR AGSLSRSKSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCAGG TGTGTGAGTC CCGGCTTGCC CGGGGCAGAG AGCTCTCGAC GGTCGGCGCG 60
CAGCCCAAGG GCGTCGGCAA AGCTTTAAGC TCCCACCGTA CGGTGAGCAC GGAACGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	66.67	1.00e-120	427.00
IUUC-Aca-004612	Anolis carolinensis	51.68	2.00e-141	495.00
IUUC-Bta-012626	Bos taurus	66.67	2.00e-120	426.00
IUUC-Cja-018853	Callithrix jacchus	47.94	3.00e-122	431.00
IUUC-Cfa-021167	Canis familiaris	47.77	4.00e-119	421.00
IUUC-Cpo-021305	Cavia porcellus	66.99	2.00e-121	429.00
IUUC-Csa-023454	Chlorocebus sabaeus	47.94	2.00e-122	432.00
IUUC-Cho-024836	Choloepus hoffmanni	67.03	6.00e-67	247.00
IUUC-Dor-031053	Dipodomys ordii	66.67	6.00e-121	427.00
IUUC-Ete-032416	Echinops telfairi	67.95	4.00e-99	355.00
IUUC-Eca-033817	Equus caballus	66.34	8.00e-121	427.00
IUUC-Fca-036400	Felis catus	66.45	4.00e-117	414.00
IUUC-Ggr-039986	Gaeumannomyces graminis	26.45	6.00e-20	93.20
IUUC-Ggo-045174	Gorilla gorilla	47.94	2.00e-122	432.00
IUUC-Hsa-046443	Homo sapiens	66.67	6.00e-121	427.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	48.70	2.00e-122	432.00
IUUC-Lch-050539	Latimeria chalumnae	48.76	6.00e-141	494.00
IUUC-Laf-053730	Loxodonta africana	49.05	2.00e-124	439.00
IUUC-Mcc-055541	Macaca mulatta	47.94	2.00e-122	432.00
IUUC-Meu-056279	Macropus eugenii	48.95	3.00e-125	442.00
IUUC-Mor-057065	Magnaporthe oryzae	29.03	5.00e-26	113.00
IUUC-Mpo-057461	Magnaporthe poae	26.81	1.00e-20	95.50
IUUC-Mmr-060913	Microcebus murinus	48.11	6.00e-120	424.00
IUUC-Mdo-061807	Monodelphis domestica	66.13	2.00e-120	426.00
IUUC-Mmu-063599	Mus musculus	66.77	4.00e-121	428.00
IUUC-Mpu-066329	Mustela putorius furo	47.77	5.00e-119	421.00
IUUC-Mlu-067359	Myotis lucifugus	45.24	7.00e-97	347.00
IUUC-Nle-070084	Nomascus leucogenys	66.02	6.00e-118	417.00
IUUC-Opr-071096	Ochotona princeps	66.34	1.00e-119	423.00
IUUC-Ocu-074228	Oryctolagus cuniculus	48.78	6.00e-122	431.00
IUUC-Oga-088007	Otolemur garnettii	62.67	2.00e-102	365.00
IUUC-Oar-090226	Ovis aries	63.35	3.00e-82	299.00
IUUC-Ptr-091522	Pan troglodytes	47.94	2.00e-122	432.00
IUUC-Pan-091954	Papio anubis	47.59	3.00e-120	425.00
IUUC-Psi-093216	Pelodiscus sinensis	53.08	2.00e-158	552.00
IUUC-Pab-098691	Pongo abelii	47.94	2.00e-122	432.00
IUUC-Pca-101133	Procavia capensis	67.91	3.00e-118	418.00
IUUC-Pva-102681	Pteropus vampyrus	48.28	2.00e-111	395.00
IUUC-Rno-105132	Rattus norvegicus	47.56	6.00e-120	424.00
IUUC-Sha-107145	Sarcophilus harrisii	47.66	2.00e-111	395.00
IUUC-Ssc-115586	Sus scrofa	47.25	3.00e-115	408.00
IUUC-Tgu-117491	Taeniopygia guttata	75.90	3.00e-84	303.00
IUUC-Tbe-127465	Tupaia belangeri	73.43	3.00e-88	319.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence