iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053346

Ensembl Protein ID

ENSLAFP00000003832.3

UniProt Accession

G3SUJ4; G3SUJ4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000004589.3	ENSLAFT00000004590.3	ENSLAFP00000003832.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	1.40e-51	174.3	15	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icdli++ +++ak+a++a++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+ellk+++e++
   Q: 15   ATSQLLLETDWESILQICDLIRQGDTQAKYAVNAIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQVEVN 103
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v++K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 104  VRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHTFP 143
           ***************************************8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGRGSGTFER LLDKATSQLL LETDWESILQ ICDLIRQGDT QAKYAVNAIK KKVNDKNPHV 60
ALYALEVMES VVKNCGQTVH DEVANKQTME ELKELLKRQV EVNVRNKILY LIQAWAHAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCGCG GCAGCGGCAC CTTCGAGCGT CTCCTAGGTA ACGCGCCCCC CCACCACGCC 60
GACAGGACGC TCTCTTCCGG CGTCTCCGCC CCGGGCTGAG TGGGCTGAGT GAGCTGGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	80.56	0.00e+00	881.00
IUUC-Apl-003662	Anas platyrhynchos	83.31	0.00e+00	907.00
IUUC-Aca-004940	Anolis carolinensis	75.99	0.00e+00	1042.00
IUUC-Ago-007931	Ashbya gossypii	30.81	4.00e-27	115.00
IUUC-Acl-008274	Aspergillus clavatus	31.05	3.00e-39	156.00
IUUC-Afl-008521	Aspergillus flavus	33.20	4.00e-40	159.00
IUUC-Afu-008774	Aspergillus fumigatus	32.59	6.00e-40	159.00
IUUC-Ani-009445	Aspergillus nidulans	32.72	5.00e-41	162.00
IUUC-Ang-009863	Aspergillus niger	32.85	4.00e-42	166.00
IUUC-Ate-010444	Aspergillus terreus	33.45	5.00e-42	165.00
IUUC-Ame-011111	Astyanax mexicanus	80.80	0.00e+00	854.00
IUUC-Bgr-012087	Blumeria graminis	31.45	2.00e-42	167.00
IUUC-Bta-012506	Bos taurus	81.85	0.00e+00	1046.00
IUUC-Bci-013782	Botrytis cinerea	30.86	2.00e-41	163.00
IUUC-Cel-018493	Caenorhabditis elegans	53.08	3.00e-68	253.00
IUUC-Cja-019998	Callithrix jacchus	80.92	0.00e+00	954.00
IUUC-Cfa-020615	Canis familiaris	82.40	0.00e+00	969.00
IUUC-Cpo-022019	Cavia porcellus	83.42	0.00e+00	1099.00
IUUC-Csa-023596	Chlorocebus sabaeus	90.58	0.00e+00	952.00
IUUC-Cin-025488	Ciona intestinalis	47.24	3.00e-126	445.00
IUUC-Csv-025802	Ciona savignyi	50.00	8.00e-115	407.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	35.07	1.00e-40	160.00
IUUC-Cne-026847	Cryptococcus neoformans	31.23	1.00e-37	151.00
IUUC-Dre-028353	Danio rerio	79.91	0.00e+00	890.00
IUUC-Dno-029005	Dasypus novemcinctus	90.09	0.00e+00	1039.00
IUUC-Dor-030280	Dipodomys ordii	80.54	0.00e+00	1029.00
IUUC-Dse-031238	Dothistroma septosporum	38.43	1.00e-42	168.00
IUUC-Dme-031952	Drosophila melanogaster	49.12	7.00e-80	291.00
IUUC-Ete-032235	Echinops telfairi	97.73	9.00e-133	467.00
IUUC-Eca-033873	Equus caballus	83.42	0.00e+00	1018.00
IUUC-Eeu-034652	Erinaceus europaeus	94.97	2.00e-103	370.00
IUUC-Fca-036563	Felis catus	81.35	0.00e+00	1017.00
IUUC-Fal-036649	Ficedula albicollis	77.50	0.00e+00	945.00
IUUC-Fox-037962	Fusarium oxysporum	33.46	5.00e-40	159.00
IUUC-Fso-038396	Fusarium solani	33.22	1.00e-40	161.00
IUUC-Gmo-039510	Gadus morhua	80.84	0.00e+00	883.00
IUUC-Ggr-039938	Gaeumannomyces graminis	33.05	1.00e-38	154.00
IUUC-Gga-040201	Gallus gallus	87.06	0.00e+00	1021.00
IUUC-Gac-041459	Gasterosteus aculeatus	79.43	0.00e+00	928.00
IUUC-Ggo-044573	Gorilla gorilla	84.10	0.00e+00	1050.00
IUUC-Hsa-046009	Homo sapiens	83.97	0.00e+00	1094.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	83.21	0.00e+00	1097.00
IUUC-Kpa-049327	Komagataella pastoris	31.86	1.00e-33	137.00
IUUC-Lch-049944	Latimeria chalumnae	77.37	2.00e-125	442.00
IUUC-Loc-051850	Lepisosteus oculatus	81.82	0.00e+00	940.00
IUUC-Lma-053252	Leptosphaeria maculans	36.09	5.00e-42	166.00
IUUC-Mcc-055789	Macaca mulatta	82.75	0.00e+00	1020.00
IUUC-Meu-056329	Macropus eugenii	70.00	9.00e-125	441.00
IUUC-Mor-057205	Magnaporthe oryzae	33.56	1.00e-38	154.00
IUUC-Mpo-057295	Magnaporthe poae	33.64	2.00e-40	160.00
IUUC-Mla-058849	Melampsora laricipopulina	32.05	8.00e-32	132.00
IUUC-Mga-059361	Meleagris gallopavo	86.18	0.00e+00	946.00
IUUC-Mvi-060561	Microbotryum violaceum	32.30	1.00e-39	157.00
IUUC-Mmr-061122	Microcebus murinus	93.13	0.00e+00	1018.00
IUUC-Mdo-062171	Monodelphis domestica	91.01	0.00e+00	1077.00
IUUC-Mmu-063952	Mus musculus	83.57	0.00e+00	1148.00
IUUC-Mpu-065852	Mustela putorius furo	82.40	0.00e+00	975.00
IUUC-Mlu-066996	Myotis lucifugus	85.89	1.00e-125	442.00
IUUC-Nfi-068539	Neosartorya fischeri	32.59	3.00e-40	159.00
IUUC-Ncr-068726	Neurospora crassa	38.74	5.00e-40	159.00
IUUC-Nle-070148	Nomascus leucogenys	78.54	0.00e+00	929.00
IUUC-Opr-070833	Ochotona princeps	78.45	0.00e+00	748.00
IUUC-Ont-071261	Oreochromis niloticus	79.88	0.00e+00	901.00
IUUC-Oan-073684	Ornithorhynchus anatinus	71.56	1.00e-161	562.00
IUUC-Ola-087570	Oryzias latipes	69.59	0.00e+00	895.00
IUUC-Oga-089087	Otolemur garnettii	79.97	0.00e+00	949.00
IUUC-Oar-089534	Ovis aries	81.85	0.00e+00	1042.00
IUUC-Ptr-091654	Pan troglodytes	78.72	0.00e+00	941.00
IUUC-Pan-092652	Papio anubis	82.95	0.00e+00	1026.00
IUUC-Pno-095125	Phaeosphaeria nodorum	36.96	3.00e-42	166.00
IUUC-Pfo-096757	Poecilia formosa	81.99	0.00e+00	862.00
IUUC-Pab-097788	Pongo abelii	92.55	0.00e+00	816.00
IUUC-Pca-100145	Procavia capensis	74.74	0.00e+00	862.00
IUUC-Pva-102965	Pteropus vampyrus	79.60	0.00e+00	975.00
IUUC-Pgr-103609	Puccinia graminis	33.66	1.00e-33	137.00
IUUC-Ptt-103865	Puccinia triticina	35.20	6.00e-34	139.00
IUUC-Pte-104095	Pyrenophora teres	35.68	2.00e-42	167.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	36.32	5.00e-42	166.00
IUUC-Rno-105125	Rattus norvegicus	83.58	0.00e+00	1049.00
IUUC-Sce-106192	Saccharomyces cerevisiae	28.38	4.00e-27	116.00
IUUC-Sha-107066	Sarcophilus harrisii	90.91	0.00e+00	1079.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	33.80	6.00e-42	165.00
IUUC-Spo-108220	Schizosaccharomyces pombe	35.19	3.00e-37	149.00
IUUC-Stu-112464	Solanum tuberosum	45.90	5.00e-13	70.50
IUUC-Sar-113393	Sorex araneus	91.05	4.00e-104	372.00
IUUC-Sre-114986	Sporisorium reilianum	39.01	2.00e-42	167.00
IUUC-Tgu-117505	Taeniopygia guttata	88.60	0.00e+00	956.00
IUUC-Tru-118494	Takifugu rubripes	78.87	0.00e+00	919.00
IUUC-Tsy-119626	Tarsius syrichta	97.94	3.00e-53	203.00
IUUC-Tni-120174	Tetraodon nigroviridis	69.23	0.00e+00	912.00
IUUC-Tre-122191	Trichoderma reesei	33.82	2.00e-41	163.00
IUUC-Tvi-122318	Trichoderma virens	33.33	3.00e-42	166.00
IUUC-Tme-126914	Tuber melanosporum	34.75	2.00e-44	173.00
IUUC-Ttr-129095	Tursiops truncatus	83.20	0.00e+00	1071.00
IUUC-Uma-129475	Ustilago maydis	36.86	4.00e-39	156.00
IUUC-Vda-129908	Verticillium dahliae	33.22	2.00e-36	147.00
IUUC-Xtr-131900	Xenopus tropicalis	72.67	0.00e+00	984.00
IUUC-Xma-133124	Xiphophorus maculatus	81.00	0.00e+00	907.00
IUUC-Yli-134682	Yarrowia lipolytica	33.45	4.00e-32	132.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence