iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097060

Ensembl Protein ID

ENSPFOP00000004336.1

UniProt Accession

A0A087XEY3; A0A087XEY3_POEFO

Genbank Protein ID

ENSPFOP00000004336

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01013526

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000004486.1	ENSPFOT00000004344.1	ENSPFOP00000004336.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-114	383.6	321	976
ULD/UDP/UBQ/UBQ_Other	9.00e-11	42.1	168	238

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+++l+e++l+ +++ ++n+enp ++ ge+++++++l++++w s++++v+pr+++++++++a++fsgy+
   Q: 321  CGLSNLGNTCFMNSALQCLSNVSPLTEYFLTdQYEAEINRENPLGMRGEIAEAYADLVKQMWMSRSSYVAPRTFKTQVGRFAPQFSGYQ 409
           7*****************************999******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ k+kp+  +++++   ++d+     a+ ++  +n+s+i+d+F+g +ks+++c+ec +vs++++pf++l
   Q: 410  QQDSQELLAFLLDGLHEDLNRVKKKPYLALRDAE--GRPDDivakeAWTNHRLRNDSVIVDIFHGLFKSTLVCPECSKVSVTFDPFCYL 496
           ****************************998888..6666667888******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+++ +e                                                                            
   Q: 497  TLPLPMKKDRTMEvflvqsdpqskptqfrvvvpklgavtdlcsalsrlcgippekmvvadvynhrfhkiyrrddalnqimekddifvye 585
           ********99999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 586  vqeedsermnlpvyfrerhskhvgsssstllfgqpllisvprhnlladvlydkilerigryvkqqhspnsesrasasatlsscsqtpec 674
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 675  stssalnaslggcgsprsdgascsasssngsnhsgtcneanglydgeeeamdhqvspepengpseeeeeeessdlengskgnaaklftf 763
           ***************************************************************************************** PP
   S: 186  ..................................................................slqdcLesftkeeelegenkyyc 208
                                                                              l++c+e ft+ e+l +++ +yc
   Q: 764  sivnsygtvnitplpcdgnvlklnphstvaidwdteskkqfydeqeaeayekhdsmlqpqkkkttvALKECIELFTTMETLGEHDPWYC 852
           ***************************************************************************************** PP
   S: 209  ekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYv 296
           ++ckk+q+a+kk++l++lP++L++hLkRfs+++  + r k+++ v+fp++ L++s+f+++p+ +   ++ Y+Liav +H+G++++GHY+
   Q: 853  PTCKKHQQATKKFDLWSLPRILVVHLKRFSYNR--CWRDKLDTLVDFPIRdLNMSEFVCDPKAG---PYVYDLIAVSNHYGGMGGGHYT 936
           *****************************9966..6778*********************9987...8********************* PP
   S: 297  ayvkne.kgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           ay kn+ +gkW++fdDs+V++ +e+++++   + aYvlfY+rr
   Q: 937  AYGKNKmDGKWYYFDDSSVSSASEDQIVT---KAAYVLFYQRR 976
           *****62566*******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + +++++++dt+ ++ ++++++++ip + + rL++k      + L ++d t++d gl++g+++++++k+++
   Q: 168  VVKRHFSKADTIDTIEKEMRTLFNIPsEKETRLWNKymsntYEQLnKPDSTVQDAGLFQGQVLVIERKNED 238
           67888*********************777*****999987744457*******************999876 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MMAEGGGPES GSAADSDTEP VAAQMPTPSI ENQKQSIGSL LKTTLKKGDE WYLIDSRWFK 60
QWKKYVGFDS WDMYNVGERS LYPGPIDNSG LFSDQETQAL KEHLIDELDY VLVPTEAWNK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTGGCACA GTTGCACTTT TATACCACTA GGGGCCCCGT TGCTCCTCCG TCTATGGATC 60
GTAGAGGAAG AACGTTTAGC GAGACGCTCG CTCCTGTGCT TCAGTCCCTG CGCGTTCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0034122--P:negative regulation of toll-like receptor signaling pathway
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	56.90	4.00e-77	283.00
IUUC-Apl-004068	Anas platyrhynchos	60.25	0.00e+00	1075.00
IUUC-Acl-008284	Aspergillus clavatus	37.47	4.00e-56	214.00
IUUC-Afl-008507	Aspergillus flavus	39.63	9.00e-58	219.00
IUUC-Afu-008878	Aspergillus fumigatus	29.31	7.00e-63	236.00
IUUC-Ang-009562	Aspergillus niger	38.81	7.00e-58	220.00
IUUC-Aor-009949	Aspergillus oryzae	36.17	4.00e-57	217.00
IUUC-Ate-010323	Aspergillus terreus	38.99	2.00e-59	224.00
IUUC-Ame-011064	Astyanax mexicanus	77.30	0.00e+00	1067.00
IUUC-Bgr-012277	Blumeria graminis	45.52	4.00e-65	244.00
IUUC-Bta-012929	Bos taurus	64.61	0.00e+00	1257.00
IUUC-Bci-013993	Botrytis cinerea	45.70	6.00e-66	246.00
IUUC-Bdi-015062	Brachypodium distachyon	41.20	3.00e-123	436.00
IUUC-Cfa-020599	Canis familiaris	65.22	0.00e+00	1233.00
IUUC-Cpo-022144	Cavia porcellus	64.50	0.00e+00	1204.00
IUUC-Csv-026109	Ciona savignyi	45.48	3.00e-149	522.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	35.00	7.00e-65	243.00
IUUC-Dre-027869	Danio rerio	80.81	0.00e+00	1518.00
IUUC-Dno-029316	Dasypus novemcinctus	66.16	0.00e+00	1251.00
IUUC-Dor-031038	Dipodomys ordii	65.84	0.00e+00	678.00
IUUC-Ete-032970	Echinops telfairi	62.14	0.00e+00	759.00
IUUC-Fal-037634	Ficedula albicollis	64.39	0.00e+00	1174.00
IUUC-Fso-038291	Fusarium solani	47.46	3.00e-68	254.00
IUUC-Gmo-038866	Gadus morhua	85.54	0.00e+00	1023.00
IUUC-Ggr-039740	Gaeumannomyces graminis	44.69	6.00e-64	240.00
IUUC-Gga-040729	Gallus gallus	58.37	0.00e+00	1115.00
IUUC-Gac-042631	Gasterosteus aculeatus	91.76	0.00e+00	1174.00
IUUC-Lch-050533	Latimeria chalumnae	67.85	0.00e+00	1163.00
IUUC-Lpe-051424	Leersia perrieri	36.88	9.00e-103	368.00
IUUC-Loc-051800	Lepisosteus oculatus	75.37	0.00e+00	1533.00
IUUC-Mpo-057486	Magnaporthe poae	45.42	7.00e-64	239.00
IUUC-Mga-059300	Meleagris gallopavo	59.77	0.00e+00	1078.00
IUUC-Mpu-066920	Mustela putorius furo	65.93	0.00e+00	1249.00
IUUC-Nfi-068330	Neosartorya fischeri	29.22	3.00e-63	238.00
IUUC-Ncr-068879	Neurospora crassa	46.13	3.00e-65	244.00
IUUC-Opr-070740	Ochotona princeps	63.71	0.00e+00	863.00
IUUC-Ont-072573	Oreochromis niloticus	90.84	0.00e+00	1759.00
IUUC-Ola-086553	Oryzias latipes	84.19	0.00e+00	1614.00
IUUC-Oga-088562	Otolemur garnettii	62.33	0.00e+00	1114.00
IUUC-Oar-090439	Ovis aries	66.49	0.00e+00	1249.00
IUUC-Psi-093942	Pelodiscus sinensis	64.05	0.00e+00	1147.00
IUUC-Pop-099801	Populus trichocarpa	37.22	7.00e-155	541.00
IUUC-Pca-100161	Procavia capensis	64.20	0.00e+00	830.00
IUUC-Pgr-103546	Puccinia graminis	29.91	4.00e-69	257.00
IUUC-Rno-106081	Rattus norvegicus	64.56	0.00e+00	1239.00
IUUC-Sha-106937	Sarcophilus harrisii	67.18	0.00e+00	1235.00
IUUC-Sly-111746	Solanum lycopersicum	38.52	2.00e-109	390.00
IUUC-Sar-113542	Sorex araneus	67.86	0.00e+00	905.00
IUUC-Ssc-115637	Sus scrofa	69.17	0.00e+00	899.00
IUUC-Tgu-117267	Taeniopygia guttata	61.84	0.00e+00	1155.00
IUUC-Tru-118634	Takifugu rubripes	89.03	0.00e+00	1081.00
IUUC-Tni-120107	Tetraodon nigroviridis	80.46	0.00e+00	1058.00
IUUC-Tre-121888	Trichoderma reesei	36.36	1.00e-65	246.00
IUUC-Tme-127062	Tuber melanosporum	32.07	2.00e-82	301.00
IUUC-Uma-129498	Ustilago maydis	40.90	2.00e-70	261.00
IUUC-Vpa-130571	Vicugna pacos	71.06	0.00e+00	870.00
IUUC-Xtr-132305	Xenopus tropicalis	64.68	0.00e+00	1243.00
IUUC-Xma-133176	Xiphophorus maculatus	97.96	0.00e+00	1626.00
IUUC-Yli-134392	Yarrowia lipolytica	44.24	1.00e-64	242.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence