iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026841

Ensembl Protein ID

AAW45817

UniProt Accession

Q5KAI7; Q5KAI7_CRYNJ

Genbank Protein ID

AAW45817.2

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AE017350

Gene Name

CNJ01540

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNJ01540	AAW45817	AAW45817

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.20e-94	313.3	733	1063

Active Site

Position(s)	Description	Evidence
1021	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfy 97
           +lk r++++fv+     E+g+d gG+ +efl+ lske+++++ gl+l ++  +++l+pnp+s+ ++  +l++++f+G++lgka++dg l+d++++ +f+
   Q: 733  ALKGRVDITFVDqygitEAGIDGGGLYKEFLTILSKEVFDSNRGLWLVTD--QNELYPNPHSYASESHNLSWYRFIGQVLGKAIYDGILVDVTFAAFFL 829
           5789999***************************************9987..566789***************************************** PP
   S: 98   klllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreG 196
            + lg++  l+dl+++d++lyk l  +k+    d + ++++ltfs++ e++g +++ +L+pgG++ipVt eN++eY++ v++y+l ++i+ q +af  G
   Q: 830  AKWLGRQSYLDDLASLDKDLYKGLIILKN----DPKPEDMALTFSTTIEEFGVQRQIDLVPGGSDIPVTAENRHEYIQHVCKYKLDKQIAAQSKAFFIG 924
           ************************99994....67888899999999999************************************************* PP
   S: 197  fneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdas 294
           ++++++ ++l++F+++el++li Ge + id++dlk++++++g + +d      Fw+v+++f++e+++a+L+FvT++sr Pl Gf +l+p+ f +r ++ 
   Q: 925  LSDLLDAKWLRMFDQQELQQLIGGEeKPIDLKDLKAHCNFDG-FPNDVTP-ALFWKVVQGFTEEQKRALLRFVTSCSRPPLLGFSQLNPQ-FGVRFNGG 1020
           *************************999************88.5555444.57***********************************99.88888677 PP
   S: 295  d.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           d drlPs++ Cfn+LkLP Y+++ +l+ kLl Ai++++gF++s
   Q: 1021 DmDRLPSASACFNLLKLPGYTTEATLRAKLLQAINSGAGFDMS 1063
           77**************************************985 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MFDPAFLLSN SKSNNVNLST STSTSSSDLL SSVRAERLAR EEKRHQELAA IEIQKVWRGR 60
KVARDFRERI LDDLERSLGI EGGLNVEKGG REMVVLLRDA KNKKDTDRKQ IVSANWCDLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGACTACA AAGTTTCTGA CAAACAGACA GCCCAGGGCG TAAAATGTTC GACCCAGCCT 60
TCCTTTTGTC CAATTCGAAG AGCAACAATG TCAACCTCTC AACCAGCACG TCCACAAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

cne:CNJ01540

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	35.33	2.00e-85	308.00
IUUC-Aml-001355	Ailuropoda melanoleuca	38.01	3.00e-98	351.00
IUUC-Atr-003017	Amborella trichopoda	36.32	3.00e-96	344.00
IUUC-Apl-003731	Anas platyrhynchos	37.16	4.00e-99	354.00
IUUC-Aca-005248	Anolis carolinensis	36.99	1.00e-97	349.00
IUUC-Aly-005794	Arabidopsis lyrata	33.90	7.00e-85	307.00
IUUC-Ath-007269	Arabidopsis thaliana	34.64	4.00e-91	327.00
IUUC-Ago-007748	Ashbya gossypii	38.02	1.00e-73	269.00
IUUC-Acl-008158	Aspergillus clavatus	37.33	7.00e-85	307.00
IUUC-Afl-008398	Aspergillus flavus	37.78	2.00e-88	318.00
IUUC-Afu-008937	Aspergillus fumigatus	37.44	7.00e-86	310.00
IUUC-Ani-009252	Aspergillus nidulans	37.87	4.00e-93	334.00
IUUC-Ang-009773	Aspergillus niger	37.01	5.00e-86	311.00
IUUC-Aor-009940	Aspergillus oryzae	37.78	2.00e-88	318.00
IUUC-Ate-010395	Aspergillus terreus	38.05	4.00e-89	321.00
IUUC-Ame-010769	Astyanax mexicanus	39.90	2.00e-73	269.00
IUUC-Bgr-012269	Blumeria graminis	39.96	3.00e-83	300.00
IUUC-Bta-012841	Bos taurus	37.66	3.00e-97	348.00
IUUC-Bci-013743	Botrytis cinerea	37.87	1.00e-95	343.00
IUUC-Bdi-014502	Brachypodium distachyon	34.82	2.00e-87	315.00
IUUC-Bol-015093	Brassica oleracea	34.81	5.00e-91	327.00
IUUC-Bra-016722	Brassica rapa	35.38	1.00e-90	326.00
IUUC-Cel-018447	Caenorhabditis elegans	36.79	3.00e-70	258.00
IUUC-Cja-019743	Callithrix jacchus	36.14	6.00e-96	343.00
IUUC-Cfa-021031	Canis familiaris	36.24	2.00e-97	348.00
IUUC-Cpo-022401	Cavia porcellus	36.99	3.00e-97	348.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	38.63	6.00e-73	267.00
IUUC-Csa-024107	Chlorocebus sabaeus	36.24	1.00e-97	349.00
IUUC-Cho-024750	Choloepus hoffmanni	41.54	2.00e-86	312.00
IUUC-Cin-025750	Ciona intestinalis	37.93	3.00e-74	271.00
IUUC-Csv-026016	Ciona savignyi	32.30	8.00e-76	276.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	37.77	3.00e-97	348.00
IUUC-Cme-027265	Cyanidioschyzon merolae	43.21	5.00e-89	320.00
IUUC-Dre-028196	Danio rerio	42.73	7.00e-97	347.00
IUUC-Dno-029024	Dasypus novemcinctus	36.41	6.00e-98	350.00
IUUC-Dor-030938	Dipodomys ordii	38.37	4.00e-74	271.00
IUUC-Dse-031416	Dothistroma septosporum	35.64	3.00e-91	328.00
IUUC-Dme-031946	Drosophila melanogaster	44.67	2.00e-93	335.00
IUUC-Eca-033828	Equus caballus	37.83	4.00e-97	347.00
IUUC-Fca-035907	Felis catus	38.30	6.00e-99	353.00
IUUC-Fal-037389	Ficedula albicollis	36.99	1.00e-98	352.00
IUUC-Fox-037788	Fusarium oxysporum	37.66	3.00e-99	354.00
IUUC-Fso-038088	Fusarium solani	35.27	1.00e-95	342.00
IUUC-Gmo-039412	Gadus morhua	37.21	1.00e-74	273.00
IUUC-Ggr-039941	Gaeumannomyces graminis	36.13	2.00e-92	332.00
IUUC-Gga-040310	Gallus gallus	37.33	7.00e-99	353.00
IUUC-Gac-042088	Gasterosteus aculeatus	37.67	1.00e-76	279.00
IUUC-Gma-042728	Glycine max	42.75	4.00e-88	318.00
IUUC-Ggo-045031	Gorilla gorilla	36.24	2.00e-97	348.00
IUUC-Hsa-045880	Homo sapiens	36.24	2.00e-97	348.00
IUUC-Hvu-047102	Hordeum vulgare	34.99	2.00e-83	302.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	38.61	4.00e-75	273.00
IUUC-Kpa-049307	Komagataella pastoris	31.21	1.00e-77	283.00
IUUC-Lch-050403	Latimeria chalumnae	35.98	3.00e-79	288.00
IUUC-Lpe-050755	Leersia perrieri	42.09	3.00e-84	305.00
IUUC-Loc-052218	Lepisosteus oculatus	37.33	3.00e-97	348.00
IUUC-Lma-053096	Leptosphaeria maculans	35.80	7.00e-87	313.00
IUUC-Laf-053902	Loxodonta africana	37.67	8.00e-77	280.00
IUUC-Mcc-055127	Macaca mulatta	36.24	2.00e-97	348.00
IUUC-Meu-056527	Macropus eugenii	39.55	6.00e-58	217.00
IUUC-Mor-057021	Magnaporthe oryzae	35.48	1.00e-86	313.00
IUUC-Mpo-057570	Magnaporthe poae	35.64	5.00e-94	337.00
IUUC-Mtr-057671	Medicago truncatula	35.53	5.00e-91	327.00
IUUC-Mla-059124	Melampsora laricipopulina	48.96	4.00e-130	456.00
IUUC-Mga-059581	Meleagris gallopavo	37.16	1.00e-98	353.00
IUUC-Mvi-060445	Microbotryum violaceum	47.79	1.00e-151	529.00
IUUC-Mmr-061360	Microcebus murinus	37.61	2.00e-97	348.00
IUUC-Mdo-062194	Monodelphis domestica	37.39	4.00e-98	351.00
IUUC-Mmu-064189	Mus musculus	37.66	4.00e-98	350.00
IUUC-Mac-064989	Musa acuminata	35.05	5.00e-86	310.00
IUUC-Mpu-066439	Mustela putorius furo	37.66	8.00e-98	350.00
IUUC-Mlu-068228	Myotis lucifugus	37.61	4.00e-98	351.00
IUUC-Nfi-068280	Neosartorya fischeri	41.19	3.00e-83	301.00
IUUC-Ncr-068869	Neurospora crassa	33.83	1.00e-95	342.00
IUUC-Nle-069687	Nomascus leucogenys	37.48	1.00e-96	346.00
IUUC-Opr-070554	Ochotona princeps	37.91	1.00e-76	279.00
IUUC-Ont-071836	Oreochromis niloticus	36.89	3.00e-96	345.00
IUUC-Oan-072800	Ornithorhynchus anatinus	37.22	3.00e-99	354.00
IUUC-Ocu-074587	Oryctolagus cuniculus	36.58	9.00e-98	350.00
IUUC-Oba-075006	Oryza barthii	41.21	2.00e-86	311.00
IUUC-Obr-076320	Oryza brachyantha	35.34	4.00e-86	311.00
IUUC-Ogl-077093	Oryza glaberrima	35.17	1.00e-85	310.00
IUUC-Ogu-078947	Oryza glumaepatula	40.70	1.00e-86	312.00
IUUC-Oin-080058	Oryza indica	35.17	4.00e-85	308.00
IUUC-Olo-080475	Oryza longistaminata	40.70	2.00e-86	312.00
IUUC-Ome-081741	Oryza meridionalis	34.31	2.00e-77	282.00
IUUC-Oni-082385	Oryza nivara	40.70	1.00e-86	312.00
IUUC-Opu-083176	Oryza punctata	40.95	5.00e-87	314.00
IUUC-Oru-084554	Oryza rufipogon	37.76	4.00e-75	275.00
IUUC-Osa-085355	Oryza sativa	40.70	1.00e-86	313.00
IUUC-Ola-087209	Oryzias latipes	36.82	1.00e-99	355.00
IUUC-Olu-087902	Ostreococcus lucimarinus	37.38	4.00e-72	263.00
IUUC-Oga-088776	Otolemur garnettii	37.79	7.00e-98	350.00
IUUC-Oar-089441	Ovis aries	37.66	4.00e-97	347.00
IUUC-Ptr-091273	Pan troglodytes	36.24	2.00e-97	348.00
IUUC-Pan-091981	Papio anubis	37.43	3.00e-97	348.00
IUUC-Psi-093251	Pelodiscus sinensis	39.00	5.00e-68	250.00
IUUC-Pma-094738	Petromyzon marinus	35.60	5.00e-99	353.00
IUUC-Pno-095132	Phaeosphaeria nodorum	30.78	1.00e-65	242.00
IUUC-Ppa-095544	Physcomitrella patens	43.17	2.00e-97	349.00
IUUC-Pfo-097511	Poecilia formosa	36.89	1.00e-97	349.00
IUUC-Pab-098634	Pongo abelii	33.79	6.00e-83	300.00
IUUC-Pop-098928	Populus trichocarpa	39.80	6.00e-81	293.00
IUUC-Pca-100987	Procavia capensis	44.68	5.00e-90	323.00
IUUC-Ppe-101281	Prunus persica	34.94	6.00e-92	330.00
IUUC-Pva-103034	Pteropus vampyrus	34.09	1.00e-82	299.00
IUUC-Pgr-103513	Puccinia graminis	41.17	7.00e-140	489.00
IUUC-Ptt-103967	Puccinia triticina	39.63	9.00e-130	456.00
IUUC-Pte-104105	Pyrenophora teres	34.11	6.00e-96	343.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	33.48	1.00e-91	329.00
IUUC-Rno-106028	Rattus norvegicus	36.11	1.00e-62	233.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.99	4.00e-76	277.00
IUUC-Sha-107108	Sarcophilus harrisii	36.44	2.00e-89	322.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	38.20	4.00e-108	384.00
IUUC-Spo-108097	Schizosaccharomyces pombe	38.18	2.00e-116	411.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	36.95	3.00e-93	335.00
IUUC-Smo-109488	Selaginella moellendorffii	43.10	3.00e-92	331.00
IUUC-Sit-109811	Setaria italica	42.34	8.00e-85	306.00
IUUC-Sly-111362	Solanum lycopersicum	40.80	2.00e-81	295.00
IUUC-Sbi-114433	Sorghum bicolor	34.82	5.00e-87	314.00
IUUC-Sre-115038	Sporisorium reilianum	40.12	3.00e-133	468.00
IUUC-Ssc-116103	Sus scrofa	37.91	1.00e-76	279.00
IUUC-Tgu-116729	Taeniopygia guttata	36.88	1.00e-98	352.00
IUUC-Tru-118068	Takifugu rubripes	36.62	1.00e-96	346.00
IUUC-Tsy-118942	Tarsius syrichta	48.44	2.00e-66	245.00
IUUC-Tni-120732	Tetraodon nigroviridis	35.86	2.00e-91	328.00
IUUC-Tca-121770	Theobroma cacao	35.79	7.00e-95	340.00
IUUC-Tre-121892	Trichoderma reesei	37.59	2.00e-94	338.00
IUUC-Tvi-122354	Trichoderma virens	34.39	3.00e-97	348.00
IUUC-Tae-125229	Triticum aestivum	33.00	5.00e-84	304.00
IUUC-Tur-126086	Triticum urartu	35.52	3.00e-85	308.00
IUUC-Tme-127102	Tuber melanosporum	35.09	3.00e-92	331.00
IUUC-Tbe-127351	Tupaia belangeri	36.31	1.00e-81	296.00
IUUC-Ttr-129061	Tursiops truncatus	44.82	5.00e-90	324.00
IUUC-Uma-129343	Ustilago maydis	39.74	1.00e-138	486.00
IUUC-Vda-129748	Verticillium dahliae	35.56	1.00e-88	319.00
IUUC-Vvi-131524	Vitis vinifera	35.85	6.00e-92	330.00
IUUC-Xtr-132094	Xenopus tropicalis	37.67	4.00e-98	350.00
IUUC-Xma-133923	Xiphophorus maculatus	36.45	1.00e-97	349.00
IUUC-Yli-134496	Yarrowia lipolytica	37.40	3.00e-83	301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence