iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048413

Ensembl Protein ID

ENSSTOP00000019857.1

UniProt Accession

I3N661; I3N661_ICTTR

Genbank Protein ID

ENSSTOP00000019857

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01079031

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000021548.1	ENSSTOT00000024274.1	ENSSTOP00000019857.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-19	69.8	36	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.50e-09	35.2	136	164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           Dv+l+ + g+ f+ah++vLaa+S++F+a+f ++l+es+  ++v +++v p+ ++ ll+F+Ytg++ 
   Q: 36   DVTLEAAgGRDFPAHRAVLAAASPYFRAMFAGQLRESR-AERVRLHGVPPDMLQLLLDFSYTGRVA 100
           9*****99******************************.************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
            Ncl++ +fA++++c  L++aa++fil+h
   Q: 136  ANCLDMQDFAEAFSCAGLASAAQRFILRH 164
           6***************************9 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MERPAPLAVL PFSDPAHALS LLRGLSQLRA ERKFLDVTLE AAGGRDFPAH RAVLAAASPY 60
FRAMFAGQLR ESRAERVRLH GVPPDMLQLL LDFSYTGRVA VSGDNAEPLL RAADLLQFPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCCATGGA GCGGCCGGCG CCCCTGGCCG TGCTGCCTTT CTCGGACCCC GCACACGCCC 60
TGAGCCTGCT GCGCGGCCTG AGCCAGCTCC GCGCCGAGCG CAAGTTCCTG GACGTGACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	87.62	0.00e+00	924.00
IUUC-Apl-003189	Anas platyrhynchos	84.76	7.00e-142	495.00
IUUC-Ame-011774	Astyanax mexicanus	65.83	2.00e-136	478.00
IUUC-Bta-012367	Bos taurus	97.15	0.00e+00	1157.00
IUUC-Cja-019501	Callithrix jacchus	90.07	0.00e+00	1041.00
IUUC-Cfa-020550	Canis familiaris	96.65	0.00e+00	1149.00
IUUC-Cpo-022072	Cavia porcellus	96.65	0.00e+00	1130.00
IUUC-Csa-023364	Chlorocebus sabaeus	97.00	0.00e+00	1016.00
IUUC-Cin-025253	Ciona intestinalis	43.82	6.00e-147	514.00
IUUC-Csv-025871	Ciona savignyi	45.01	5.00e-153	534.00
IUUC-Dre-028694	Danio rerio	72.54	0.00e+00	857.00
IUUC-Dno-029082	Dasypus novemcinctus	93.76	0.00e+00	952.00
IUUC-Dor-030680	Dipodomys ordii	97.15	0.00e+00	1159.00
IUUC-Ete-032315	Echinops telfairi	94.66	0.00e+00	962.00
IUUC-Eca-033570	Equus caballus	94.89	0.00e+00	697.00
IUUC-Eeu-035067	Erinaceus europaeus	93.36	3.00e-144	505.00
IUUC-Fca-035663	Felis catus	90.21	4.00e-125	439.00
IUUC-Fal-037103	Ficedula albicollis	83.72	0.00e+00	894.00
IUUC-Gmo-039420	Gadus morhua	70.42	0.00e+00	834.00
IUUC-Gga-040161	Gallus gallus	81.21	0.00e+00	866.00
IUUC-Gac-041755	Gasterosteus aculeatus	72.11	0.00e+00	858.00
IUUC-Ggo-044899	Gorilla gorilla	96.82	0.00e+00	1133.00
IUUC-Hsa-045834	Homo sapiens	96.82	0.00e+00	1131.00
IUUC-Lch-050338	Latimeria chalumnae	71.11	0.00e+00	874.00
IUUC-Loc-051780	Lepisosteus oculatus	75.13	0.00e+00	879.00
IUUC-Laf-053725	Loxodonta africana	95.25	0.00e+00	800.00
IUUC-Mcc-055032	Macaca mulatta	99.00	0.00e+00	981.00
IUUC-Meu-056661	Macropus eugenii	94.57	0.00e+00	768.00
IUUC-Mpo-057626	Magnaporthe poae	31.67	3.00e-07	49.70
IUUC-Mga-059821	Meleagris gallopavo	80.93	7.00e-127	445.00
IUUC-Mdo-062095	Monodelphis domestica	95.26	0.00e+00	960.00
IUUC-Mmu-063138	Mus musculus	96.82	0.00e+00	1150.00
IUUC-Mpu-066386	Mustela putorius furo	95.03	0.00e+00	640.00
IUUC-Mlu-067807	Myotis lucifugus	94.38	0.00e+00	699.00
IUUC-Nle-069181	Nomascus leucogenys	96.31	0.00e+00	1136.00
IUUC-Opr-070658	Ochotona princeps	96.98	0.00e+00	1182.00
IUUC-Ont-072209	Oreochromis niloticus	71.48	0.00e+00	847.00
IUUC-Oan-072861	Ornithorhynchus anatinus	91.51	5.00e-118	416.00
IUUC-Ocu-074631	Oryctolagus cuniculus	87.38	0.00e+00	1007.00
IUUC-Ola-087553	Oryzias latipes	70.60	0.00e+00	837.00
IUUC-Oga-088782	Otolemur garnettii	97.32	0.00e+00	1155.00
IUUC-Oar-089634	Ovis aries	96.82	0.00e+00	1152.00
IUUC-Ptr-091259	Pan troglodytes	96.41	0.00e+00	840.00
IUUC-Pan-091734	Papio anubis	97.15	0.00e+00	1137.00
IUUC-Psi-092979	Pelodiscus sinensis	82.83	0.00e+00	918.00
IUUC-Pma-094459	Petromyzon marinus	53.99	4.00e-125	441.00
IUUC-Pfo-097446	Poecilia formosa	71.48	0.00e+00	847.00
IUUC-Pab-098765	Pongo abelii	96.98	0.00e+00	1149.00
IUUC-Pca-101018	Procavia capensis	99.42	6.00e-94	338.00
IUUC-Pva-102730	Pteropus vampyrus	93.13	0.00e+00	1099.00
IUUC-Rno-104972	Rattus norvegicus	96.15	0.00e+00	1146.00
IUUC-Ssc-115869	Sus scrofa	98.61	0.00e+00	985.00
IUUC-Tgu-116562	Taeniopygia guttata	83.57	0.00e+00	926.00
IUUC-Tru-118490	Takifugu rubripes	70.95	0.00e+00	842.00
IUUC-Tni-119898	Tetraodon nigroviridis	69.19	0.00e+00	810.00
IUUC-Ttr-128976	Tursiops truncatus	94.14	3.00e-146	511.00
IUUC-Xtr-132876	Xenopus tropicalis	74.56	0.00e+00	905.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence