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Tag Content
UUCD2 ID IUUC-Mlu-067267
UUCD1 version UUC-MyL-00002
Ensembl Protein ID ENSMLUP00000000090.2
UniProt Accession G1NSI2; G1NSI2_MYOLU
Genbank Protein ID ENSMLUP00000000090
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAPE02038083
Gene Name PAFAH1B1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000000095.2 ENSMLUT00000000095.2 ENSMLUP00000000090.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-58 192.5 232 268
UBD/Beta-Prp 6.80e-95 317.7 107 410
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+ ++  +d tl++s+s+D t++vW + t  +
   Q: 232  GHREWVRMVRPnQDgTLIASCSNDQTVRVWVVATKEC 268
           8**********9888***************8877666 PP
   

   UBD/Beta-Prp
   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h s++t v f+p  s+++++s+d+tikvwd++tg++ r+l+gh++ v++++f+++gk+l+++s D+tik+wd++ ++c++t++gh+++v
   Q: 107  HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNV 195
           5668888********************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
            s++++p+gd++vs+s+d+ti++w+++tg+c++ t++gh+++v++v+ ++dg l++s+s+D+tvr+W ++t+++  +l++ h++ v+++
   Q: 196  SSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVK-TFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE-HEHVVECI 282
           *********************************.*********************************************9.******** PP
   S: 187  sfdsng....................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgd 255
           s+ +++                    ++l+sgs+d+t+k+wd++tg c++tl gh+++v+ v f++ +++++s+++D+++r+Wd++++ 
   Q: 283  SWAPESsytsiseatgsetkksgkpgPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 371
           ***************************************************************************************** PP
   S: 256  llktlqlhnssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++ktl+ h++ v+s ++ + + +++v+gs d++v++w+++
   Q: 372  CMKTLNAHEHFVTSLDF-HKTAPYVVTGSVDQTVKVWECR 410
           *****************.99*****************985 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
SGLGFKKRDD RNRAIADYLR SNGYEEAYSV FKKEAELDMN EELDKKYAGL LEKKWTSVIR 60
LQKKVMELES KLNEAKEEFT SGGPLGQKRD PKEWIPRPPE KYALSGHRSP VTRVIFHPVF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067267|E3,WD_repeat;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCGGGTTTGG GATTTAAAAA GAGAGATGAT AGCTAGGATT GAAGTGAGTT TATTGTACCA 60
GTGGTAGAAC ATTACTAGTT ATGTTATGTA CTACAGGTTG GTTTTAAAAA CAAGTATTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067267|E3,WD_repeat;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08513--LisH
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00667--LisH
SM00320--WD40
Gene Ontology

GO:0000235--C:astral microtubule
GO:1904115--C:axon cytoplasm
GO:0005938--C:cell cortex
GO:0031252--C:cell leading edge
GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0000776--C:kinetochore
GO:0005875--C:microtubule associated complex
GO:0031514--C:motile cilium
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0032420--C:stereocilium
GO:0001675--P:acrosome assembly
GO:0030036--P:actin cytoskeleton organization
GO:0008344--P:adult locomotory behavior
GO:0001667--P:ameboidal-type cell migration
GO:0060117--P:auditory receptor cell development
GO:0048854--P:brain morphogenesis
GO:0051301--P:cell division
GO:0007268--P:chemical synaptic transmission
GO:0090102--P:cochlea development
GO:0021540--P:corpus callosum morphogenesis
GO:0043622--P:cortical microtubule organization
GO:0000132--P:establishment of mitotic spindle orientation
GO:0042249--P:establishment of planar polarity of embryonic epithelium
GO:0021766--P:hippocampus development
GO:0021819--P:layer formation in cerebral cortex
GO:0007611--P:learning or memory
GO:0051661--P:maintenance of centrosome location
GO:0090176--P:microtubule cytoskeleton organization involved in establishment of planar polarity
GO:0031023--P:microtubule organizing center organization
GO:0007067--P:mitotic nuclear division
GO:0046329--P:negative regulation of JNK cascade
GO:0007405--P:neuroblast proliferation
GO:0050885--P:neuromuscular process controlling balance
GO:0001764--P:neuron migration
GO:0051081--P:nuclear envelope disassembly
GO:0036035--P:osteoclast development
GO:0001961--P:positive regulation of cytokine-mediated signaling pathway
GO:0061003--P:positive regulation of dendritic spine morphogenesis
GO:0040019--P:positive regulation of embryonic development
GO:0009306--P:protein secretion
GO:0043087--P:regulation of GTPase activity
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0008090--P:retrograde axonal transport
GO:0019226--P:transmission of nerve impulse
GO:0047496--P:vesicle transport along microtubule
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001589 Ailuropoda melanoleuca 99.75 0.00e+00 834.00
IUUC-Apl-004024 Anas platyrhynchos 97.06 0.00e+00 833.00
IUUC-Aca-004564 Anolis carolinensis 97.06 0.00e+00 827.00
IUUC-Ago-007862 Ashbya gossypii 27.08 5.00e-37 148.00
IUUC-Acl-008360 Aspergillus clavatus 45.66 4.00e-102 364.00
IUUC-Afl-008502 Aspergillus flavus 45.69 2.00e-94 339.00
IUUC-Afu-008848 Aspergillus fumigatus 46.32 1.00e-103 370.00
IUUC-Ani-009173 Aspergillus nidulans 42.86 2.00e-88 319.00
IUUC-Ang-009873 Aspergillus niger 43.91 5.00e-92 331.00
IUUC-Aor-009973 Aspergillus oryzae 43.04 3.00e-89 322.00
IUUC-Ate-010523 Aspergillus terreus 41.16 5.00e-88 318.00
IUUC-Ame-010969 Astyanax mexicanus 93.38 0.00e+00 804.00
IUUC-Bgr-011972 Blumeria graminis 46.75 3.00e-102 365.00
IUUC-Bta-013106 Bos taurus 98.28 0.00e+00 838.00
IUUC-Bci-013615 Botrytis cinerea 43.61 5.00e-96 344.00
IUUC-Cel-018459 Caenorhabditis elegans 56.72 1.00e-145 509.00
IUUC-Cja-018755 Callithrix jacchus 98.05 0.00e+00 835.00
IUUC-Cfa-020749 Canis familiaris 98.28 0.00e+00 838.00
IUUC-Cpo-022371 Cavia porcellus 98.28 0.00e+00 838.00
IUUC-Cre-022578 Chlamydomonas reinhardtii 35.44 6.00e-50 190.00
IUUC-Csa-023524 Chlorocebus sabaeus 99.13 0.00e+00 718.00
IUUC-Cho-024764 Choloepus hoffmanni 88.95 0.00e+00 677.00
IUUC-Cin-025753 Ciona intestinalis 69.68 2.00e-176 611.00
IUUC-Csv-025817 Ciona savignyi 68.14 4.00e-179 620.00
IUUC-Cgl-026529 Colletotrichum gloeosporioides 45.97 9.00e-95 340.00
IUUC-Cne-027087 Cryptococcus neoformans 50.39 5.00e-110 390.00
IUUC-Dre-027554 Danio rerio 93.14 0.00e+00 799.00
IUUC-Dno-029050 Dasypus novemcinctus 98.04 0.00e+00 838.00
IUUC-Dor-030222 Dipodomys ordii 89.95 0.00e+00 755.00
IUUC-Dse-031164 Dothistroma septosporum 42.72 4.00e-99 355.00
IUUC-Dme-031745 Drosophila melanogaster 68.22 5.00e-167 580.00
IUUC-Ete-032508 Echinops telfairi 80.88 0.00e+00 668.00
IUUC-Eca-034288 Equus caballus 99.25 0.00e+00 828.00
IUUC-Eeu-034984 Erinaceus europaeus 89.71 0.00e+00 752.00
IUUC-Fca-036498 Felis catus 98.28 0.00e+00 838.00
IUUC-Fal-036920 Ficedula albicollis 97.06 0.00e+00 833.00
IUUC-Fox-037996 Fusarium oxysporum 45.22 1.00e-101 363.00
IUUC-Fso-038160 Fusarium solani 43.26 1.00e-96 346.00
IUUC-Gmo-038983 Gadus morhua 92.40 0.00e+00 795.00
IUUC-Ggr-040051 Gaeumannomyces graminis 46.11 3.00e-96 345.00
IUUC-Gga-040623 Gallus gallus 97.06 0.00e+00 833.00
IUUC-Gac-041613 Gasterosteus aculeatus 91.42 0.00e+00 790.00
IUUC-Ggo-045410 Gorilla gorilla 88.97 0.00e+00 723.00
IUUC-Hsa-046358 Homo sapiens 98.04 0.00e+00 836.00
IUUC-Itr-047890 Ictidomys tridecemlineatus 98.28 0.00e+00 838.00
IUUC-Kpa-049351 Komagataella pastoris 29.23 4.00e-41 162.00
IUUC-Lch-049936 Latimeria chalumnae 95.34 0.00e+00 816.00
IUUC-Loc-052476 Lepisosteus oculatus 94.33 0.00e+00 803.00
IUUC-Lma-053170 Leptosphaeria maculans 48.42 1.00e-98 353.00
IUUC-Laf-053713 Loxodonta africana 99.50 0.00e+00 831.00
IUUC-Mcc-054628 Macaca mulatta 97.79 0.00e+00 835.00
IUUC-Meu-055927 Macropus eugenii 85.92 1.00e-139 488.00
IUUC-Mor-056962 Magnaporthe oryzae 44.26 2.00e-95 342.00
IUUC-Mpo-057583 Magnaporthe poae 46.15 5.00e-92 331.00
IUUC-Mla-058819 Melampsora laricipopulina 47.09 2.00e-115 409.00
IUUC-Mga-059945 Meleagris gallopavo 96.81 0.00e+00 832.00
IUUC-Mvi-060403 Microbotryum violaceum 48.88 3.00e-125 441.00
IUUC-Mmr-061289 Microcebus murinus 98.28 0.00e+00 832.00
IUUC-Mdo-061912 Monodelphis domestica 97.55 0.00e+00 832.00
IUUC-Mmu-063253 Mus musculus 98.28 0.00e+00 838.00
IUUC-Mpu-066638 Mustela putorius furo 98.28 0.00e+00 838.00
IUUC-Nfi-068571 Neosartorya fischeri 44.69 6.00e-96 344.00
IUUC-Ncr-068895 Neurospora crassa 50.13 2.00e-103 369.00
IUUC-Nle-069087 Nomascus leucogenys 97.60 0.00e+00 680.00
IUUC-Opr-070579 Ochotona princeps 98.04 0.00e+00 838.00
IUUC-Ont-072432 Oreochromis niloticus 92.89 0.00e+00 803.00
IUUC-Oan-073072 Ornithorhynchus anatinus 98.28 0.00e+00 838.00
IUUC-Ocu-074180 Oryctolagus cuniculus 98.04 0.00e+00 838.00
IUUC-Ola-086772 Oryzias latipes 92.65 0.00e+00 796.00
IUUC-Oga-088219 Otolemur garnettii 99.50 0.00e+00 834.00
IUUC-Oar-090394 Ovis aries 98.28 0.00e+00 838.00
IUUC-Ptr-091517 Pan troglodytes 98.28 0.00e+00 838.00
IUUC-Pan-092421 Papio anubis 97.79 0.00e+00 835.00
IUUC-Psi-093370 Pelodiscus sinensis 97.30 0.00e+00 833.00
IUUC-Pma-094319 Petromyzon marinus 88.83 0.00e+00 642.00
IUUC-Pno-094815 Phaeosphaeria nodorum 46.51 2.00e-101 362.00
IUUC-Pfo-097089 Poecilia formosa 92.16 0.00e+00 796.00
IUUC-Pab-098421 Pongo abelii 98.28 0.00e+00 838.00
IUUC-Pca-100120 Procavia capensis 72.03 4.00e-162 564.00
IUUC-Pva-102960 Pteropus vampyrus 98.04 0.00e+00 834.00
IUUC-Pgr-103538 Puccinia graminis 46.21 1.00e-114 406.00
IUUC-Ptt-103990 Puccinia triticina 40.32 5.00e-41 162.00
IUUC-Pte-104261 Pyrenophora teres 46.75 2.00e-101 362.00
IUUC-Pyt-104780 Pyrenophora triticirepentis 46.99 9.00e-102 363.00
IUUC-Rno-105123 Rattus norvegicus 98.28 0.00e+00 838.00
IUUC-Sce-106208 Saccharomyces cerevisiae 28.73 3.00e-36 146.00
IUUC-Sha-107010 Sarcophilus harrisii 97.30 0.00e+00 830.00
IUUC-Sja-107899 Schizosaccharomyces japonicus 32.04 1.00e-62 234.00
IUUC-Ssl-108571 Sclerotinia sclerotiorum 43.86 3.00e-96 345.00
IUUC-Sar-113309 Sorex araneus 99.00 0.00e+00 823.00
IUUC-Sre-115003 Sporisorium reilianum 48.97 6.00e-122 430.00
IUUC-Ssc-116148 Sus scrofa 98.28 0.00e+00 838.00
IUUC-Tgu-117299 Taeniopygia guttata 96.81 0.00e+00 830.00
IUUC-Tru-118179 Takifugu rubripes 90.44 0.00e+00 790.00
IUUC-Tsy-119493 Tarsius syrichta 96.81 0.00e+00 822.00
IUUC-Tni-120355 Tetraodon nigroviridis 91.67 0.00e+00 764.00
IUUC-Tre-121977 Trichoderma reesei 42.37 7.00e-99 353.00
IUUC-Tvi-122661 Trichoderma virens 42.89 1.00e-97 349.00
IUUC-Tme-127031 Tuber melanosporum 47.50 2.00e-101 362.00
IUUC-Tbe-127492 Tupaia belangeri 83.08 2.00e-115 409.00
IUUC-Ttr-128929 Tursiops truncatus 98.04 0.00e+00 836.00
IUUC-Uma-129347 Ustilago maydis 46.68 1.00e-118 419.00
IUUC-Vda-129837 Verticillium dahliae 45.54 2.00e-97 349.00
IUUC-Vpa-130532 Vicugna pacos 83.59 0.00e+00 647.00
IUUC-Xtr-131985 Xenopus tropicalis 95.83 0.00e+00 825.00
IUUC-Xma-133314 Xiphophorus maculatus 92.65 0.00e+00 798.00
IUUC-Yli-134403 Yarrowia lipolytica 40.81 2.00e-73 270.00
Created Date 25-Jun-2017

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