iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fso-038393

Ensembl Protein ID

NechaP104408

UniProt Accession

C7YR46; C7YR46_NECH7

Genbank Protein ID

EEU45392.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

GG698899

Gene Name

NECHADRAFT_104408

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NechaG104408	NechaT104408	NechaP104408

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.90e-125	416.3	481	813

Active Site

Position(s)	Description	Evidence
782	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyk 98
           + dlkkrl+++f gE+gld+gG++ref++lls+e++np ++lf+ys+ d++tlq+np+sg+ npehl++F+f+Gr++g+a++++r+ld+++  ++yk
   Q: 481  ATDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGI-NPEHLNYFKFIGRVVGLAIFHRRFLDAFFIGALYK 576
           579*********************************************************9.89********************************* PP
   S: 99   lllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafre 195
           ++lgk + l d+e vd+++++sl+++++n   di+   l+ tfs+++e +g +++e+L+p+G+ni+VtneNk+eYv+l+v++r++++i+eq++af+e
   Q: 577  MMLGKAVALADMEGVDADFHRSLQWMLDN---DISGGILEQTFSTEDERFGVMTTEDLIPNGRNIDVTNENKKEYVDLMVKWRIEKRIAEQFQAFKE 670
           ***************************99...9**************************************************************** PP
   S: 196  GfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfv 288
           Gf+e+ip++l+++F+e+elelli G +eidv+d+kk+t y+g yte+++++q+Fw ++++++ e+++++LqF+Tg+sr+P++Gf++l+    pr+f+
   Q: 671  GFQELIPQDLINVFDERELELLIGGIAEIDVDDWKKHTDYRG-YTESDEVVQNFWATVRSWDGEQKSRLLQFTTGTSRIPVNGFKDLQgsdgPRRFT 766
           ****************************************76.****************************************************** PP
   S: 289  irkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           i+k+++ ++lP+++TCfn+L+LP Y+s e l++kL++A+eet gF++
   Q: 767  IEKAGEITNLPKAHTCFNRLDLPAYKSLEMLQQKLTIAVEETMGFGQ 813
           ***9999**************************************96 PP

Organism

Fusarium solani

Protein Sequence
(Fasta)

MTSRTDSGLP NSSVDIILVI AADGLYKRDV FRFPDPFAVA TINGEQTKTT TVSKRTLNPY 60
WNESFDFRSN EDSILAVQVF DQKKFKKKDQ GFLGVINIRV GDVMPELSAD ADDQMLTRDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCAGTC GCACCGATTC CGGGCTGCCC AAGTAGGTTC ATTCCCAGCC GCCCATCCAT 60
CGCATCGCGT TCTGCGCCTG CGAAGGGGCA TTCTATCCAT TCGGCCCCTT CACGATACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR024928--E3_ub_ligase_SMURF1
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

nhe:NECHADRAFT_104408

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	46.23	8.00e-150	522.00
IUUC-Apl-003752	Anas platyrhynchos	47.55	9.00e-157	545.00
IUUC-Aca-005338	Anolis carolinensis	46.03	6.00e-151	526.00
IUUC-Ago-007742	Ashbya gossypii	65.24	0.00e+00	1014.00
IUUC-Acl-008273	Aspergillus clavatus	72.68	0.00e+00	1117.00
IUUC-Afl-008713	Aspergillus flavus	72.63	0.00e+00	1117.00
IUUC-Afu-009103	Aspergillus fumigatus	70.57	0.00e+00	1098.00
IUUC-Ani-009259	Aspergillus nidulans	70.89	0.00e+00	1121.00
IUUC-Ang-009738	Aspergillus niger	72.15	0.00e+00	1136.00
IUUC-Aor-010053	Aspergillus oryzae	78.33	1.00e-143	500.00
IUUC-Ate-010529	Aspergillus terreus	72.88	0.00e+00	1124.00
IUUC-Ame-010810	Astyanax mexicanus	50.62	3.00e-139	487.00
IUUC-Bgr-012148	Blumeria graminis	77.35	0.00e+00	1177.00
IUUC-Bta-012782	Bos taurus	47.37	8.00e-156	542.00
IUUC-Bci-013785	Botrytis cinerea	77.31	0.00e+00	1232.00
IUUC-Cel-018299	Caenorhabditis elegans	42.57	4.00e-139	486.00
IUUC-Cja-018732	Callithrix jacchus	46.55	6.00e-150	523.00
IUUC-Cfa-021226	Canis familiaris	44.24	2.00e-150	524.00
IUUC-Cpo-021671	Cavia porcellus	46.23	7.00e-150	523.00
IUUC-Csa-023252	Chlorocebus sabaeus	47.03	8.00e-156	542.00
IUUC-Cho-024695	Choloepus hoffmanni	44.80	1.00e-154	538.00
IUUC-Cin-025212	Ciona intestinalis	45.70	5.00e-147	513.00
IUUC-Csv-026256	Ciona savignyi	45.64	5.00e-146	509.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	87.41	0.00e+00	1384.00
IUUC-Cne-026849	Cryptococcus neoformans	60.47	0.00e+00	974.00
IUUC-Dre-028245	Danio rerio	45.29	2.00e-151	527.00
IUUC-Dno-029466	Dasypus novemcinctus	46.23	5.00e-150	523.00
IUUC-Dor-030138	Dipodomys ordii	46.05	2.00e-145	508.00
IUUC-Dse-031241	Dothistroma septosporum	71.29	0.00e+00	1140.00
IUUC-Dme-032041	Drosophila melanogaster	44.61	1.00e-138	486.00
IUUC-Ete-032779	Echinops telfairi	44.19	6.00e-138	483.00
IUUC-Eca-033445	Equus caballus	46.55	1.00e-149	522.00
IUUC-Eeu-035247	Erinaceus europaeus	46.28	6.00e-150	523.00
IUUC-Fca-035605	Felis catus	47.21	2.00e-155	541.00
IUUC-Fal-037126	Ficedula albicollis	47.38	8.00e-156	542.00
IUUC-Fox-037774	Fusarium oxysporum	95.33	0.00e+00	1474.00
IUUC-Gmo-039674	Gadus morhua	43.83	7.00e-146	509.00
IUUC-Ggr-040107	Gaeumannomyces graminis	84.31	0.00e+00	1347.00
IUUC-Gga-041276	Gallus gallus	43.98	2.00e-149	521.00
IUUC-Gac-042020	Gasterosteus aculeatus	45.95	2.00e-147	514.00
IUUC-Ggo-045332	Gorilla gorilla	46.55	9.00e-150	522.00
IUUC-Hsa-045968	Homo sapiens	46.55	6.00e-150	523.00
IUUC-Itr-048918	Ictidomys tridecemlineatus	47.20	1.00e-155	541.00
IUUC-Kpa-049273	Komagataella pastoris	66.25	0.00e+00	1035.00
IUUC-Lch-050443	Latimeria chalumnae	45.88	9.00e-151	525.00
IUUC-Loc-052645	Lepisosteus oculatus	46.43	5.00e-149	520.00
IUUC-Lma-052980	Leptosphaeria maculans	70.75	0.00e+00	683.00
IUUC-Laf-054383	Loxodonta africana	45.51	2.00e-156	544.00
IUUC-Mcc-055821	Macaca mulatta	46.55	5.00e-150	523.00
IUUC-Meu-055953	Macropus eugenii	39.81	1.00e-114	405.00
IUUC-Mor-057097	Magnaporthe oryzae	86.17	0.00e+00	1395.00
IUUC-Mpo-057442	Magnaporthe poae	81.20	0.00e+00	1221.00
IUUC-Mla-058996	Melampsora laricipopulina	62.23	0.00e+00	983.00
IUUC-Mga-059661	Meleagris gallopavo	47.38	6.00e-156	543.00
IUUC-Mvi-060395	Microbotryum violaceum	78.26	0.00e+00	811.00
IUUC-Mmr-061135	Microcebus murinus	47.37	4.00e-156	543.00
IUUC-Mdo-062505	Monodelphis domestica	47.04	2.00e-155	541.00
IUUC-Mmu-064136	Mus musculus	46.39	4.00e-150	523.00
IUUC-Mpu-066765	Mustela putorius furo	46.55	9.00e-150	522.00
IUUC-Mlu-067837	Myotis lucifugus	47.54	1.00e-156	545.00
IUUC-Nfi-068427	Neosartorya fischeri	71.83	0.00e+00	1119.00
IUUC-Ncr-068918	Neurospora crassa	80.12	0.00e+00	1255.00
IUUC-Nle-069244	Nomascus leucogenys	47.37	5.00e-156	543.00
IUUC-Opr-071044	Ochotona princeps	46.28	7.00e-150	523.00
IUUC-Ont-071664	Oreochromis niloticus	46.95	2.00e-142	498.00
IUUC-Oan-073497	Ornithorhynchus anatinus	44.24	2.00e-151	527.00
IUUC-Ocu-074298	Oryctolagus cuniculus	47.37	8.00e-156	542.00
IUUC-Ola-087467	Oryzias latipes	45.26	9.00e-148	516.00
IUUC-Oga-088460	Otolemur garnettii	46.55	1.00e-149	522.00
IUUC-Oar-090198	Ovis aries	45.14	9.00e-151	526.00
IUUC-Ptr-090939	Pan troglodytes	46.55	6.00e-150	523.00
IUUC-Pan-092284	Papio anubis	46.55	7.00e-150	523.00
IUUC-Psi-093645	Pelodiscus sinensis	43.96	1.00e-150	525.00
IUUC-Pma-094364	Petromyzon marinus	50.70	1.00e-139	487.00
IUUC-Pno-095118	Phaeosphaeria nodorum	70.60	0.00e+00	1139.00
IUUC-Pfo-097145	Poecilia formosa	46.84	3.00e-144	504.00
IUUC-Pab-098088	Pongo abelii	46.23	8.00e-150	523.00
IUUC-Pca-100568	Procavia capensis	43.17	3.00e-132	464.00
IUUC-Pva-102354	Pteropus vampyrus	46.58	2.00e-149	521.00
IUUC-Pgr-103620	Puccinia graminis	68.09	0.00e+00	842.00
IUUC-Ptt-103806	Puccinia triticina	76.81	0.00e+00	682.00
IUUC-Pte-104016	Pyrenophora teres	71.74	0.00e+00	1142.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	71.74	0.00e+00	1142.00
IUUC-Rno-105318	Rattus norvegicus	46.39	3.00e-150	524.00
IUUC-Sce-106289	Saccharomyces cerevisiae	64.82	0.00e+00	1008.00
IUUC-Sha-107175	Sarcophilus harrisii	47.04	3.00e-155	540.00
IUUC-Sja-107941	Schizosaccharomyces japonicus	65.09	0.00e+00	1019.00
IUUC-Spo-108171	Schizosaccharomyces pombe	65.56	0.00e+00	1019.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	76.51	0.00e+00	1224.00
IUUC-Sar-113761	Sorex araneus	47.20	1.00e-154	538.00
IUUC-Sre-114929	Sporisorium reilianum	70.78	0.00e+00	873.00
IUUC-Ssc-115368	Sus scrofa	45.72	4.00e-149	520.00
IUUC-Tgu-117130	Taeniopygia guttata	44.75	1.00e-150	525.00
IUUC-Tru-118610	Takifugu rubripes	52.06	7.00e-146	509.00
IUUC-Tsy-119492	Tarsius syrichta	46.38	1.00e-148	519.00
IUUC-Tni-119993	Tetraodon nigroviridis	46.99	1.00e-145	509.00
IUUC-Tre-122203	Trichoderma reesei	86.53	0.00e+00	1354.00
IUUC-Tvi-122595	Trichoderma virens	85.25	0.00e+00	1373.00
IUUC-Tme-126897	Tuber melanosporum	70.34	0.00e+00	1059.00
IUUC-Tbe-127408	Tupaia belangeri	43.82	9.00e-129	453.00
IUUC-Ttr-128275	Tursiops truncatus	46.11	3.00e-148	517.00
IUUC-Uma-129332	Ustilago maydis	70.78	0.00e+00	848.00
IUUC-Vda-129753	Verticillium dahliae	84.34	0.00e+00	1285.00
IUUC-Vpa-130503	Vicugna pacos	50.82	3.00e-135	474.00
IUUC-Xtr-132859	Xenopus tropicalis	46.77	6.00e-150	523.00
IUUC-Xma-133797	Xiphophorus maculatus	45.60	3.00e-150	524.00
IUUC-Yli-134668	Yarrowia lipolytica	72.71	0.00e+00	931.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence