iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-009119

Ensembl Protein ID

CADAFUAP00006363

UniProt Accession

Q4WVX2; Q4WVX2_ASPFU

Genbank Protein ID

EAL91254.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

AAHF01000003

Gene Name

AFUA_5G13620

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00006363	CADAFUAT00006363	CADAFUAP00006363

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.20e-49	165.7	146	592

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgyeqqD 91
           Gl N  N+CY NS++Q L+++ +l+e+l + + ++l ++     + +  ++l+ ++e l    +++++   p el++        +s+ +qqD
   Q: 146  GLGNWDNSCYQNSIIQGLASLLSLAEFLEH-NIRTLGDK----GSFSTHQALRGVIERLNnadNHDQRLWIPAELKS--------MSSWQQQD 225
           99*************************999.55555544....4556667777777777433355666666666554........45689*** PP
   S: 92   aqEflaflldqleeelkkeknkpkeeeeeedkselsde..............aeekkkkknkslisdlFqgqlksqikclecdnvs.sreepf 169
           aqE+++ ++ q++ e+++ ++k++++  + +  + + e               ++++   ++ l  + ++g l +++ c +c+ +   +  pf
   Q: 226  AQEYFSKVVGQVDHEVQQ-ATKRRTRNLGLK-MAGPVEniigaephtdvdgaDSSSPRLAERHLTRNPLEGLLAQRVGCMKCGWTEgLSLIPF 316
           ****************44.333333333333.23333367999999999997778888888999*******************9999****** PP
   S: 170  ldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck.................................................. 212
           + l++p+ g+ e    ++++cL++++  e +eg   ++c kc+                                                  
   Q: 317  NCLTVPLGGQYEY---DVRQCLDQYMHLEPIEG---VECAKCTllrakdqlenllnqieedmklpntpdsskvsgalrtsaeerlraveeale 403
           ***********99...****************9...999999999999999999999999999999999999999999988888888888888 PP
   S: 213  ....................kkqe..aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke......... 274
                                  +   +++  + + P++L++h++R  f+e++++ +k+   v fp  Ldl+++c  +++++           
   Q: 404  eddfaektlskkchipsknrV--TstKSRQAVIARTPKCLVIHINRSMFDENTGMLRKNYAAVRFPNVLDLNEWCLGTKSSSWGqmdierwgt 494
           888888877766666665553..05589*************************************************5544433777888888 PP
   S: 275  .................kkkYeLiavvvHsGslssGHYvayvkn.....................ekgkWllfdDskVtevkeeevleetgst 329
                             + +eL avv H+G +++GHY++y k                      + ++W++++D+ V+ v+e++v +  +  
   Q: 495  dpresmlpeagsasdvpGRFFELRAVVTHYGRHENGHYICYRKYpsdvfpahvpdtvleadgekdKAERWFRLSDDDVQMVSEASVMS--QGG 585
           888888888888888889999***********************999*999999999999886544444******************9..589 PP
   S: 330  aYvlfYk 336
           a++lfY+
   Q: 586  AFMLFYE 592
           ******8 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MNARRGGFDI LTQSPFHNPQ NSQHETFLQR LQSNNNTLTY GVAIGLLVYF VLNYFGVAPI 60
LISRALWNLI VYLTPSRIVV ALDSKTSNLD STDKALLSMN FQTKSEAMQR ILGLNNSSLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATGCTC GAAGAGGGGG ATTTGACATC CTCACTCAGA GTCCTTTCCA TAACCCTCAA 60
AATAGCCAGC ATGAGACGTT CCTGCAGCGG TTGCAGAGTA ATAATAACAC TCTGACCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

afm:AFUA_5G13620

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	29.52	9.00e-10	56.60
IUUC-Aly-005754	Arabidopsis lyrata	25.76	4.00e-19	87.80
IUUC-Ath-007622	Arabidopsis thaliana	25.35	4.00e-16	77.40
IUUC-Ago-007761	Ashbya gossypii	29.00	2.00e-27	115.00
IUUC-Acl-008136	Aspergillus clavatus	74.89	0.00e+00	984.00
IUUC-Afl-008729	Aspergillus flavus	66.39	0.00e+00	791.00
IUUC-Ani-009286	Aspergillus nidulans	61.44	0.00e+00	735.00
IUUC-Ang-009521	Aspergillus niger	64.40	0.00e+00	809.00
IUUC-Aor-009965	Aspergillus oryzae	66.16	0.00e+00	789.00
IUUC-Ate-010591	Aspergillus terreus	68.57	0.00e+00	843.00
IUUC-Bgr-012133	Blumeria graminis	42.48	3.00e-116	410.00
IUUC-Bci-013590	Botrytis cinerea	41.39	9.00e-111	392.00
IUUC-Bdi-014795	Brachypodium distachyon	28.11	1.00e-11	62.40
IUUC-Bol-015637	Brassica oleracea	24.79	2.00e-18	85.50
IUUC-Bra-016801	Brassica rapa	25.68	1.00e-19	89.40
IUUC-Cgl-026621	Colletotrichum gloeosporioides	38.64	6.00e-104	370.00
IUUC-Cne-027061	Cryptococcus neoformans	28.83	5.00e-28	117.00
IUUC-Dre-027563	Danio rerio	22.08	1.00e-16	79.30
IUUC-Dse-031252	Dothistroma septosporum	41.80	1.00e-112	398.00
IUUC-Dme-031627	Drosophila melanogaster	26.29	1.00e-10	59.70
IUUC-Fox-037820	Fusarium oxysporum	36.83	3.00e-82	297.00
IUUC-Fso-038309	Fusarium solani	39.73	2.00e-102	364.00
IUUC-Ggr-040099	Gaeumannomyces graminis	41.49	2.00e-68	251.00
IUUC-Kpa-049268	Komagataella pastoris	26.85	2.00e-41	161.00
IUUC-Lpe-051078	Leersia perrieri	20.78	1.00e-11	62.80
IUUC-Lma-053048	Leptosphaeria maculans	44.91	5.00e-99	353.00
IUUC-Meu-056673	Macropus eugenii	24.40	1.00e-09	55.80
IUUC-Mor-057143	Magnaporthe oryzae	37.79	2.00e-104	371.00
IUUC-Mpo-057548	Magnaporthe poae	37.38	7.00e-90	323.00
IUUC-Mla-058970	Melampsora laricipopulina	23.87	8.00e-30	123.00
IUUC-Mvi-060332	Microbotryum violaceum	22.90	1.00e-17	83.20
IUUC-Nfi-068306	Neosartorya fischeri	96.21	0.00e+00	1085.00
IUUC-Ncr-068741	Neurospora crassa	37.07	8.00e-99	352.00
IUUC-Oan-072916	Ornithorhynchus anatinus	21.46	7.00e-10	57.00
IUUC-Oba-075765	Oryza barthii	22.20	6.00e-11	60.50
IUUC-Obr-076005	Oryza brachyantha	21.77	2.00e-12	65.50
IUUC-Ogl-077916	Oryza glaberrima	21.81	1.00e-11	63.20
IUUC-Ogu-078263	Oryza glumaepatula	21.81	6.00e-11	60.80
IUUC-Ome-081928	Oryza meridionalis	21.33	2.00e-12	65.50
IUUC-Oni-082424	Oryza nivara	21.81	4.00e-10	57.80
IUUC-Opu-083371	Oryza punctata	22.47	1.00e-11	63.50
IUUC-Oru-085117	Oryza rufipogon	21.81	4.00e-10	57.80
IUUC-Pno-094855	Phaeosphaeria nodorum	43.88	1.00e-41	161.00
IUUC-Ppa-096015	Physcomitrella patens	23.82	5.00e-13	67.80
IUUC-Ppe-101898	Prunus persica	23.79	6.00e-16	77.40
IUUC-Pgr-103686	Puccinia graminis	25.35	8.00e-23	100.00
IUUC-Ptt-103779	Puccinia triticina	22.68	1.00e-19	90.10
IUUC-Pte-104330	Pyrenophora teres	44.36	6.00e-102	363.00
IUUC-Pyt-104518	Pyrenophora triticirepentis	43.84	8.00e-105	372.00
IUUC-Sce-106422	Saccharomyces cerevisiae	29.30	3.00e-25	108.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	40.29	2.00e-111	395.00
IUUC-Sit-110442	Setaria italica	22.66	3.00e-16	78.20
IUUC-Stu-112223	Solanum tuberosum	25.24	5.00e-07	47.40
IUUC-Sbi-113851	Sorghum bicolor	28.26	5.00e-10	56.20
IUUC-Sre-114910	Sporisorium reilianum	24.21	2.00e-21	95.50
IUUC-Tre-122225	Trichoderma reesei	40.91	2.00e-107	381.00
IUUC-Tvi-122277	Trichoderma virens	38.27	1.00e-102	365.00
IUUC-Tae-125383	Triticum aestivum	23.76	1.00e-10	59.70
IUUC-Tur-126458	Triticum urartu	25.15	1.00e-11	62.80
IUUC-Tme-126935	Tuber melanosporum	29.56	3.00e-41	161.00
IUUC-Uma-129375	Ustilago maydis	25.09	1.00e-28	120.00
IUUC-Vda-129789	Verticillium dahliae	40.63	3.00e-101	361.00
IUUC-Xtr-132374	Xenopus tropicalis	22.54	1.00e-17	82.80
IUUC-Yli-134571	Yarrowia lipolytica	26.63	2.00e-32	132.00
IUUC-Zma-135796	Zea mays	20.86	6.00e-14	70.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence