iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036383

Ensembl Protein ID

ENSFCAP00000021388.1

UniProt Accession

M3X438; M3X438_FELCA

Genbank Protein ID

ENSFCAP00000021388

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02023212

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000030664.1	ENSFCAT00000025108.1	ENSFCAP00000021388.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-09	37.2	103	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 103  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 142
           **********999999*************......**********7 PP

Organism

Felis catus

Protein Sequence
(Fasta)

QGSQQPPGSP LSREEGEAPP PAPVPEGRRR SRRVRLRGSC RHRPSFLGRR ELGTSASAGP 60
APASSEIMAS AAKEFKMDNF SPKAGTSKLQ QTVPADASPD SKCPICLDRF DNVSYLDRCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGTCGC AGCAGCCGCC GGGGTCTCCG CTGTCTCGCG AGGAGGGTGA AGCGCCCCCG 60
CCCGCTCCCG TTCCTGAGGG CCGGCGGAGA AGTCGTCGAG TACGCCTTCG CGGATCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	2.00e-09	55.80
IUUC-Aml-002240	Ailuropoda melanoleuca	96.59	0.00e+00	985.00
IUUC-Atr-002964	Amborella trichopoda	34.38	7.00e-13	67.40
IUUC-Apl-003666	Anas platyrhynchos	61.14	3.00e-140	492.00
IUUC-Aca-005305	Anolis carolinensis	61.10	4.00e-146	512.00
IUUC-Aly-005926	Arabidopsis lyrata	36.17	3.00e-11	62.00
IUUC-Ath-007299	Arabidopsis thaliana	35.11	1.00e-11	63.50
IUUC-Ame-011109	Astyanax mexicanus	51.84	2.00e-113	403.00
IUUC-Bta-012637	Bos taurus	90.54	0.00e+00	913.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	63.20
IUUC-Bol-015307	Brassica oleracea	32.98	3.00e-10	58.50
IUUC-Bra-017073	Brassica rapa	44.90	2.00e-08	52.40
IUUC-Cja-019105	Callithrix jacchus	92.35	0.00e+00	970.00
IUUC-Cfa-021203	Canis familiaris	97.10	0.00e+00	964.00
IUUC-Cpo-022335	Cavia porcellus	83.91	0.00e+00	841.00
IUUC-Csa-023870	Chlorocebus sabaeus	92.18	0.00e+00	943.00
IUUC-Cho-024870	Choloepus hoffmanni	90.66	0.00e+00	862.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	4.00e-07	50.40
IUUC-Dre-027535	Danio rerio	49.89	8.00e-120	424.00
IUUC-Dno-028963	Dasypus novemcinctus	91.33	0.00e+00	850.00
IUUC-Dor-030239	Dipodomys ordii	89.14	0.00e+00	776.00
IUUC-Dme-031941	Drosophila melanogaster	32.40	1.00e-36	148.00
IUUC-Ete-032300	Echinops telfairi	84.32	0.00e+00	1127.00
IUUC-Eca-033690	Equus caballus	93.70	0.00e+00	898.00
IUUC-Eeu-035257	Erinaceus europaeus	89.32	0.00e+00	880.00
IUUC-Fal-037209	Ficedula albicollis	69.58	8.00e-160	557.00
IUUC-Gmo-039416	Gadus morhua	53.52	5.00e-121	427.00
IUUC-Gga-041267	Gallus gallus	70.46	4.00e-173	602.00
IUUC-Gac-042227	Gasterosteus aculeatus	52.08	3.00e-117	415.00
IUUC-Gma-042777	Glycine max	33.71	2.00e-09	56.20
IUUC-Ggo-044445	Gorilla gorilla	92.01	0.00e+00	958.00
IUUC-Hsa-045844	Homo sapiens	92.18	0.00e+00	960.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	7.00e-11	58.20
IUUC-Itr-048818	Ictidomys tridecemlineatus	91.84	0.00e+00	922.00
IUUC-Lch-050031	Latimeria chalumnae	67.04	1.00e-167	583.00
IUUC-Lpe-051274	Leersia perrieri	37.74	9.00e-09	53.90
IUUC-Loc-052944	Lepisosteus oculatus	57.25	5.00e-140	491.00
IUUC-Laf-053820	Loxodonta africana	92.78	0.00e+00	857.00
IUUC-Mcc-054800	Macaca mulatta	92.19	0.00e+00	944.00
IUUC-Meu-056806	Macropus eugenii	74.39	0.00e+00	637.00
IUUC-Mtr-058378	Medicago truncatula	35.51	9.00e-13	67.00
IUUC-Mla-059017	Melampsora laricipopulina	36.07	4.00e-09	55.80
IUUC-Mvi-060417	Microbotryum violaceum	25.09	6.00e-16	79.70
IUUC-Mmr-061481	Microcebus murinus	93.37	0.00e+00	910.00
IUUC-Mdo-062219	Monodelphis domestica	81.45	3.00e-108	386.00
IUUC-Mmu-064138	Mus musculus	86.98	0.00e+00	812.00
IUUC-Mac-064635	Musa acuminata	38.57	5.00e-11	60.10
IUUC-Mlu-067088	Myotis lucifugus	91.00	0.00e+00	906.00
IUUC-Nle-069862	Nomascus leucogenys	92.02	0.00e+00	958.00
IUUC-Opr-071076	Ochotona princeps	90.91	0.00e+00	810.00
IUUC-Ont-072225	Oreochromis niloticus	51.36	4.00e-112	399.00
IUUC-Oan-073069	Ornithorhynchus anatinus	65.60	7.00e-156	543.00
IUUC-Ocu-074826	Oryctolagus cuniculus	91.51	0.00e+00	926.00
IUUC-Oba-075429	Oryza barthii	37.68	1.00e-10	60.10
IUUC-Obr-076084	Oryza brachyantha	36.23	4.00e-10	58.50
IUUC-Ogl-077444	Oryza glaberrima	37.68	1.00e-10	60.10
IUUC-Ogu-078603	Oryza glumaepatula	37.68	1.00e-10	60.10
IUUC-Oin-079777	Oryza indica	37.68	1.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	1.00e-10	60.10
IUUC-Opu-083698	Oryza punctata	36.62	7.00e-10	57.80
IUUC-Oru-084305	Oryza rufipogon	37.68	1.00e-10	60.10
IUUC-Ola-087377	Oryzias latipes	54.99	8.00e-110	390.00
IUUC-Oga-088059	Otolemur garnettii	89.46	0.00e+00	922.00
IUUC-Oar-089592	Ovis aries	89.64	0.00e+00	880.00
IUUC-Ptr-091233	Pan troglodytes	92.01	0.00e+00	957.00
IUUC-Pan-092743	Papio anubis	92.35	0.00e+00	945.00
IUUC-Psi-093669	Pelodiscus sinensis	60.06	0.00e+00	835.00
IUUC-Ppa-095668	Physcomitrella patens	27.30	5.00e-23	102.00
IUUC-Pfo-096706	Poecilia formosa	54.61	2.00e-106	380.00
IUUC-Pop-099119	Populus trichocarpa	23.15	4.00e-10	58.50
IUUC-Pca-100967	Procavia capensis	89.84	0.00e+00	802.00
IUUC-Ppe-101958	Prunus persica	38.96	5.00e-10	58.20
IUUC-Pva-102982	Pteropus vampyrus	94.22	0.00e+00	920.00
IUUC-Pgr-103551	Puccinia graminis	38.46	7.00e-09	54.30
IUUC-Ptt-103977	Puccinia triticina	33.33	5.00e-08	51.20
IUUC-Rno-105730	Rattus norvegicus	85.99	0.00e+00	772.00
IUUC-Sha-106588	Sarcophilus harrisii	70.33	0.00e+00	627.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.70
IUUC-Smo-109039	Selaginella moellendorffii	25.00	1.00e-19	90.50
IUUC-Sly-110956	Solanum lycopersicum	24.75	6.00e-10	57.80
IUUC-Stu-111938	Solanum tuberosum	24.23	2.00e-07	49.30
IUUC-Sar-113622	Sorex araneus	90.86	1.00e-162	566.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.40
IUUC-Ssc-115244	Sus scrofa	94.56	0.00e+00	875.00
IUUC-Tgu-117180	Taeniopygia guttata	64.08	4.00e-167	581.00
IUUC-Tru-118393	Takifugu rubripes	52.81	4.00e-121	428.00
IUUC-Tsy-119408	Tarsius syrichta	93.00	0.00e+00	917.00
IUUC-Tni-120664	Tetraodon nigroviridis	56.26	8.00e-120	424.00
IUUC-Tca-121712	Theobroma cacao	26.54	2.00e-16	79.30
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.50
IUUC-Tbe-127301	Tupaia belangeri	84.69	0.00e+00	802.00
IUUC-Ttr-128204	Tursiops truncatus	92.97	0.00e+00	944.00
IUUC-Uma-129420	Ustilago maydis	43.06	7.00e-10	57.80
IUUC-Vpa-130297	Vicugna pacos	93.97	0.00e+00	893.00
IUUC-Vvi-131157	Vitis vinifera	25.17	8.00e-17	80.90
IUUC-Xtr-132845	Xenopus tropicalis	66.82	2.00e-169	588.00
IUUC-Xma-133439	Xiphophorus maculatus	54.32	5.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence