iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002087

Ensembl Protein ID

ENSAMEP00000013236.1

UniProt Accession

G1M1M5; G1M1M5_AILME

Genbank Protein ID

ENSAMEP00000013236

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01162154

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000012489.1	ENSAMET00000013793.1	ENSAMEP00000013236.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	80.17	0.00e+00	1853.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

PTPQNRVRGE VSPTMTSTGQ DSTTTRQRRS RHNPHSPPHD SSVTSKRGVK KGALLHSSPS 60
LAEVKKKGRM KKLSQAAEQD LIVGLQGLDL NLEAKTLSGT GLVFDEQLNE FHCLWDDSFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCACTCCCC AGAACCGCGT CAGGGGTGAA GTCTCCCCGA CCATGACCTC CACCGGCCAG 60
GATTCCACCA CAACCAGGCA GCGAAGGAGT AGGCATAACC CCCATTCGCC CCCCCACGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	41.88	2.00e-72	266.00
IUUC-Atr-002745	Amborella trichopoda	43.75	8.00e-86	311.00
IUUC-Aca-004303	Anolis carolinensis	49.30	0.00e+00	1145.00
IUUC-Aly-006432	Arabidopsis lyrata	44.44	4.00e-83	302.00
IUUC-Ath-007355	Arabidopsis thaliana	44.78	1.00e-87	317.00
IUUC-Ago-007972	Ashbya gossypii	41.49	4.00e-82	299.00
IUUC-Acl-008187	Aspergillus clavatus	45.19	2.00e-85	310.00
IUUC-Afl-008399	Aspergillus flavus	48.15	2.00e-48	186.00
IUUC-Afu-008954	Aspergillus fumigatus	37.90	3.00e-73	269.00
IUUC-Ani-009142	Aspergillus nidulans	43.13	1.00e-77	284.00
IUUC-Ang-009522	Aspergillus niger	35.37	3.00e-48	186.00
IUUC-Aor-010069	Aspergillus oryzae	42.32	4.00e-76	279.00
IUUC-Ate-010291	Aspergillus terreus	43.58	8.00e-85	308.00
IUUC-Ame-010780	Astyanax mexicanus	50.95	0.00e+00	788.00
IUUC-Bta-013052	Bos taurus	78.98	0.00e+00	1765.00
IUUC-Bci-013789	Botrytis cinerea	40.00	7.00e-78	285.00
IUUC-Bdi-014007	Brachypodium distachyon	44.17	9.00e-88	318.00
IUUC-Bol-015468	Brassica oleracea	44.69	3.00e-84	306.00
IUUC-Bra-016680	Brassica rapa	44.97	6.00e-85	308.00
IUUC-Cel-018220	Caenorhabditis elegans	37.62	2.00e-146	513.00
IUUC-Cja-019473	Callithrix jacchus	76.43	0.00e+00	1736.00
IUUC-Cfa-020263	Canis familiaris	88.93	0.00e+00	1992.00
IUUC-Cpo-021691	Cavia porcellus	80.26	0.00e+00	1818.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	54.63	3.00e-57	214.00
IUUC-Csa-024223	Chlorocebus sabaeus	78.74	0.00e+00	1801.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	39.79	6.00e-79	288.00
IUUC-Cne-026978	Cryptococcus neoformans	43.00	2.00e-88	320.00
IUUC-Dre-028820	Danio rerio	49.87	0.00e+00	1061.00
IUUC-Dno-029160	Dasypus novemcinctus	75.02	0.00e+00	1680.00
IUUC-Dor-030859	Dipodomys ordii	71.31	0.00e+00	1634.00
IUUC-Dse-031186	Dothistroma septosporum	41.45	3.00e-81	296.00
IUUC-Dme-031963	Drosophila melanogaster	44.68	0.00e+00	692.00
IUUC-Ete-032279	Echinops telfairi	67.38	9.00e-159	554.00
IUUC-Eca-033842	Equus caballus	85.34	0.00e+00	1971.00
IUUC-Eeu-034487	Erinaceus europaeus	78.57	3.00e-161	562.00
IUUC-Fca-036430	Felis catus	87.40	0.00e+00	1960.00
IUUC-Fox-038067	Fusarium oxysporum	42.12	2.00e-82	300.00
IUUC-Fso-038263	Fusarium solani	41.16	2.00e-83	303.00
IUUC-Ggr-040062	Gaeumannomyces graminis	42.45	4.00e-75	276.00
IUUC-Gma-043738	Glycine max	45.83	1.00e-88	320.00
IUUC-Ggo-045022	Gorilla gorilla	79.06	0.00e+00	1799.00
IUUC-Hsa-046904	Homo sapiens	78.66	0.00e+00	1788.00
IUUC-Hvu-047285	Hordeum vulgare	46.44	3.00e-86	311.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	80.43	0.00e+00	1859.00
IUUC-Kpa-049281	Komagataella pastoris	40.92	4.00e-85	309.00
IUUC-Lch-050330	Latimeria chalumnae	47.51	0.00e+00	959.00
IUUC-Lpe-051214	Leersia perrieri	38.84	6.00e-89	322.00
IUUC-Lma-053263	Leptosphaeria maculans	44.64	7.00e-89	322.00
IUUC-Laf-053386	Loxodonta africana	77.58	0.00e+00	1759.00
IUUC-Mcc-055530	Macaca mulatta	78.57	0.00e+00	1783.00
IUUC-Meu-056442	Macropus eugenii	67.59	0.00e+00	966.00
IUUC-Mor-057095	Magnaporthe oryzae	40.20	2.00e-86	313.00
IUUC-Mpo-057389	Magnaporthe poae	42.17	2.00e-75	276.00
IUUC-Mtr-058463	Medicago truncatula	44.01	6.00e-90	325.00
IUUC-Mla-059143	Melampsora laricipopulina	42.63	2.00e-84	306.00
IUUC-Mmr-060637	Microcebus murinus	80.50	0.00e+00	1892.00
IUUC-Mdo-062198	Monodelphis domestica	67.44	0.00e+00	1079.00
IUUC-Mmu-063346	Mus musculus	74.33	0.00e+00	1706.00
IUUC-Mac-064630	Musa acuminata	45.40	8.00e-85	308.00
IUUC-Mpu-065884	Mustela putorius furo	91.62	0.00e+00	2101.00
IUUC-Mlu-068117	Myotis lucifugus	82.18	0.00e+00	1830.00
IUUC-Nfi-068404	Neosartorya fischeri	44.12	1.00e-84	307.00
IUUC-Ncr-068672	Neurospora crassa	40.68	3.00e-83	303.00
IUUC-Nle-069868	Nomascus leucogenys	91.95	0.00e+00	747.00
IUUC-Opr-071074	Ochotona princeps	67.07	0.00e+00	1056.00
IUUC-Ont-072246	Oreochromis niloticus	46.12	0.00e+00	936.00
IUUC-Oan-072911	Ornithorhynchus anatinus	69.72	9.00e-109	388.00
IUUC-Ocu-074627	Oryctolagus cuniculus	80.72	0.00e+00	1900.00
IUUC-Oba-075489	Oryza barthii	46.46	7.00e-87	314.00
IUUC-Obr-076150	Oryza brachyantha	46.30	6.00e-87	315.00
IUUC-Ogl-077437	Oryza glaberrima	43.66	3.00e-87	316.00
IUUC-Ogu-078370	Oryza glumaepatula	43.94	6.00e-88	318.00
IUUC-Oin-079210	Oryza indica	43.94	4.00e-88	318.00
IUUC-Olo-080971	Oryza longistaminata	47.31	2.00e-75	276.00
IUUC-Oni-082031	Oryza nivara	43.94	8.00e-88	318.00
IUUC-Opu-083471	Oryza punctata	45.85	8.00e-87	314.00
IUUC-Oru-084755	Oryza rufipogon	43.94	5.00e-88	318.00
IUUC-Osa-085447	Oryza sativa	43.94	5.00e-88	318.00
IUUC-Oga-089155	Otolemur garnettii	78.81	0.00e+00	1825.00
IUUC-Oar-089620	Ovis aries	79.15	0.00e+00	1794.00
IUUC-Ptr-090812	Pan troglodytes	88.87	0.00e+00	1264.00
IUUC-Pan-092340	Papio anubis	78.49	0.00e+00	1781.00
IUUC-Pma-094386	Petromyzon marinus	53.55	0.00e+00	810.00
IUUC-Pno-095131	Phaeosphaeria nodorum	48.06	3.00e-76	279.00
IUUC-Ppa-095550	Physcomitrella patens	46.56	4.00e-91	329.00
IUUC-Pfo-096110	Poecilia formosa	56.30	0.00e+00	727.00
IUUC-Pab-098422	Pongo abelii	78.22	0.00e+00	1763.00
IUUC-Pop-099174	Populus trichocarpa	38.27	4.00e-84	306.00
IUUC-Pca-100833	Procavia capensis	74.64	0.00e+00	1588.00
IUUC-Ppe-101644	Prunus persica	42.48	4.00e-89	322.00
IUUC-Pva-102410	Pteropus vampyrus	78.68	0.00e+00	1734.00
IUUC-Ptt-103841	Puccinia triticina	39.80	5.00e-82	298.00
IUUC-Pte-104383	Pyrenophora teres	43.32	4.00e-85	309.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	43.85	1.00e-85	311.00
IUUC-Rno-105131	Rattus norvegicus	74.63	0.00e+00	1704.00
IUUC-Sce-106274	Saccharomyces cerevisiae	39.74	1.00e-80	293.00
IUUC-Sha-106661	Sarcophilus harrisii	55.83	0.00e+00	827.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	42.86	5.00e-88	318.00
IUUC-Spo-108300	Schizosaccharomyces pombe	45.78	3.00e-88	319.00
IUUC-Smo-109615	Selaginella moellendorffii	46.35	3.00e-88	319.00
IUUC-Sit-110160	Setaria italica	43.13	5.00e-83	302.00
IUUC-Sly-111164	Solanum lycopersicum	39.66	2.00e-83	303.00
IUUC-Stu-112685	Solanum tuberosum	42.78	4.00e-72	265.00
IUUC-Sar-113692	Sorex araneus	68.73	0.00e+00	796.00
IUUC-Sbi-114301	Sorghum bicolor	46.79	2.00e-82	300.00
IUUC-Sre-115013	Sporisorium reilianum	42.00	4.00e-83	302.00
IUUC-Ssc-115724	Sus scrofa	82.46	0.00e+00	1771.00
IUUC-Tgu-116605	Taeniopygia guttata	47.86	0.00e+00	688.00
IUUC-Tru-117614	Takifugu rubripes	54.97	0.00e+00	857.00
IUUC-Tsy-118807	Tarsius syrichta	71.07	0.00e+00	935.00
IUUC-Tni-119809	Tetraodon nigroviridis	56.33	0.00e+00	810.00
IUUC-Tca-121312	Theobroma cacao	46.81	6.00e-87	315.00
IUUC-Tre-121930	Trichoderma reesei	37.63	1.00e-85	311.00
IUUC-Tvi-122373	Trichoderma virens	41.69	2.00e-84	306.00
IUUC-Tae-123064	Triticum aestivum	41.53	2.00e-79	289.00
IUUC-Tme-127027	Tuber melanosporum	42.78	2.00e-71	263.00
IUUC-Tbe-127675	Tupaia belangeri	51.97	1.00e-86	314.00
IUUC-Ttr-128411	Tursiops truncatus	79.74	0.00e+00	1830.00
IUUC-Uma-129408	Ustilago maydis	47.40	1.00e-76	281.00
IUUC-Vda-129994	Verticillium dahliae	38.18	2.00e-75	276.00
IUUC-Vpa-130525	Vicugna pacos	82.45	4.00e-66	246.00
IUUC-Vvi-131038	Vitis vinifera	42.98	9.00e-88	317.00
IUUC-Xtr-132618	Xenopus tropicalis	51.13	0.00e+00	1103.00
IUUC-Xma-133730	Xiphophorus maculatus	49.81	0.00e+00	721.00
IUUC-Yli-134680	Yarrowia lipolytica	42.53	4.00e-85	309.00
IUUC-Zma-135110	Zea mays	46.30	3.00e-83	302.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence