iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048058

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01023135

Gene Name

SPOP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000007851.2	ENSSTOT00000007850.2	ENSSTOP00000007024.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.50e-33	112.7	200	266
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.90e-09	34.7	299	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D++l+v+g+ef+ahk++Laa+S+vF+a+f++e+eesk k++vei+dv+pevf+++++F+Ytgk+++ 
   Q: 200  TDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESK-KNRVEINDVEPEVFKEMMCFIYTGKAPNL 266
           7*************************************.*************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           +eN+++il +Adl+++++Lk +a+dfi++h 
   Q: 299  VENAAEILILADLHSADQLKTQAVDFINYHA 329
           79***************************95 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSRVPSPPPP AEMSSGPVAE SWCYTQIKVV KFSYMWTINN FSFCREEMGE VIKSSTFSSG 60
ANDKLKWCLR VNPKGLDEES KDYLSLYLLL VSCPKSEVRA KFKFSILNAK GEETKAMESQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAAGGG TTCCAAGTCC TCCACCTCCG GCAGAAATGT CGAGTGGCCC TGTAGCTGAG 60
AGCTGGTGCT ACACTCAGGT AATTTCTTGA TTCACCCTGT AAATCTTGCA TCTTGGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR002083--MATH/TRAF_dom
IPR011333--SKP1/BTB/POZ
IPR034089--SPOP_C
IPR008974--TRAF-like

PROSITE

PS50097--BTB
PS50144--MATH

Pfam

PF00651--BTB
PF00917--MATH

SMART

SM00225--BTB
SM00061--MATH

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016607--C:nuclear speck
GO:0042593--P:glucose homeostasis
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:2000676--P:positive regulation of type B pancreatic cell apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000920	Aegilops tauschii	31.22	2.00e-40	159.00
IUUC-Aml-002307	Ailuropoda melanoleuca	93.04	0.00e+00	665.00
IUUC-Apl-003488	Anas platyrhynchos	97.56	0.00e+00	681.00
IUUC-Aca-005010	Anolis carolinensis	97.29	0.00e+00	679.00
IUUC-Aly-005426	Arabidopsis lyrata	30.40	8.00e-41	160.00
IUUC-Afl-008594	Aspergillus flavus	38.46	2.00e-03	35.40
IUUC-Aor-009945	Aspergillus oryzae	38.46	4.00e-04	36.20
IUUC-Bgr-012157	Blumeria graminis	35.00	8.00e-05	40.40
IUUC-Bta-012931	Bos taurus	97.83	0.00e+00	682.00
IUUC-Bdi-014743	Brachypodium distachyon	32.55	3.00e-43	168.00
IUUC-Bol-015794	Brassica oleracea	30.68	5.00e-41	161.00
IUUC-Cel-018671	Caenorhabditis elegans	65.71	5.00e-135	474.00
IUUC-Cja-019981	Callithrix jacchus	97.57	0.00e+00	677.00
IUUC-Cfa-020115	Canis familiaris	97.83	0.00e+00	682.00
IUUC-Cpo-021366	Cavia porcellus	97.30	0.00e+00	675.00
IUUC-Cre-022954	Chlamydomonas reinhardtii	32.09	2.00e-06	48.10
IUUC-Cgl-026729	Colletotrichum gloeosporioides	30.30	9.00e-06	44.30
IUUC-Dre-027603	Danio rerio	95.12	0.00e+00	662.00
IUUC-Dno-029006	Dasypus novemcinctus	91.71	9.00e-177	612.00
IUUC-Dor-030503	Dipodomys ordii	97.83	0.00e+00	681.00
IUUC-Ete-032328	Echinops telfairi	97.08	2.00e-179	620.00
IUUC-Eca-033238	Equus caballus	97.83	0.00e+00	682.00
IUUC-Eeu-034739	Erinaceus europaeus	81.57	6.00e-166	576.00
IUUC-Fca-035435	Felis catus	97.83	0.00e+00	682.00
IUUC-Gmo-038600	Gadus morhua	93.77	0.00e+00	659.00
IUUC-Gga-040441	Gallus gallus	97.56	0.00e+00	681.00
IUUC-Gac-041911	Gasterosteus aculeatus	94.58	0.00e+00	662.00
IUUC-Gma-043318	Glycine max	30.45	2.00e-35	142.00
IUUC-Hsa-045835	Homo sapiens	97.83	0.00e+00	682.00
IUUC-Hvu-047528	Hordeum vulgare	31.10	5.00e-40	158.00
IUUC-Lch-050241	Latimeria chalumnae	96.48	0.00e+00	675.00
IUUC-Loc-052374	Lepisosteus oculatus	96.75	0.00e+00	675.00
IUUC-Laf-054192	Loxodonta africana	97.57	0.00e+00	677.00
IUUC-Mcc-055322	Macaca mulatta	97.83	0.00e+00	682.00
IUUC-Meu-056330	Macropus eugenii	90.51	0.00e+00	626.00
IUUC-Mor-057237	Magnaporthe oryzae	29.41	8.00e-08	50.40
IUUC-Mpo-057466	Magnaporthe poae	28.36	7.00e-08	50.40
IUUC-Mtr-058679	Medicago truncatula	29.75	4.00e-40	158.00
IUUC-Mga-059579	Meleagris gallopavo	93.02	0.00e+00	667.00
IUUC-Mmr-061309	Microcebus murinus	97.83	0.00e+00	682.00
IUUC-Mmu-064227	Mus musculus	97.83	0.00e+00	682.00
IUUC-Mpu-065693	Mustela putorius furo	97.83	0.00e+00	682.00
IUUC-Mlu-067827	Myotis lucifugus	93.43	0.00e+00	708.00
IUUC-Nle-069393	Nomascus leucogenys	97.83	0.00e+00	682.00
IUUC-Opr-070490	Ochotona princeps	95.93	0.00e+00	666.00
IUUC-Ont-071726	Oreochromis niloticus	94.85	0.00e+00	664.00
IUUC-Ocu-074932	Oryctolagus cuniculus	97.83	0.00e+00	682.00
IUUC-Obr-076031	Oryza brachyantha	28.96	2.00e-32	133.00
IUUC-Ogu-078752	Oryza glumaepatula	34.39	7.00e-39	155.00
IUUC-Olo-080833	Oryza longistaminata	32.65	2.00e-37	149.00
IUUC-Ome-081184	Oryza meridionalis	33.33	2.00e-38	154.00
IUUC-Opu-083303	Oryza punctata	32.51	2.00e-28	120.00
IUUC-Ola-086989	Oryzias latipes	94.59	0.00e+00	659.00
IUUC-Olu-087691	Ostreococcus lucimarinus	31.23	5.00e-35	141.00
IUUC-Oga-089107	Otolemur garnettii	97.83	0.00e+00	682.00
IUUC-Oar-089943	Ovis aries	97.57	0.00e+00	677.00
IUUC-Ptr-091201	Pan troglodytes	97.83	0.00e+00	682.00
IUUC-Pan-092504	Papio anubis	97.83	0.00e+00	682.00
IUUC-Psi-093063	Pelodiscus sinensis	97.56	0.00e+00	681.00
IUUC-Ppa-095322	Physcomitrella patens	31.47	6.00e-41	161.00
IUUC-Pfo-096411	Poecilia formosa	94.85	0.00e+00	664.00
IUUC-Pab-098640	Pongo abelii	97.83	0.00e+00	682.00
IUUC-Pop-099477	Populus trichocarpa	32.40	3.00e-40	158.00
IUUC-Pca-100243	Procavia capensis	81.13	4.00e-121	427.00
IUUC-Pva-102296	Pteropus vampyrus	90.79	2.00e-177	614.00
IUUC-Pyt-104526	Pyrenophora triticirepentis	23.53	7.00e-07	47.80
IUUC-Rno-105399	Rattus norvegicus	97.83	0.00e+00	682.00
IUUC-Sha-106700	Sarcophilus harrisii	97.29	0.00e+00	679.00
IUUC-Spo-108262	Schizosaccharomyces pombe	36.84	1.10e-01	32.00
IUUC-Ssl-108548	Sclerotinia sclerotiorum	28.77	1.00e-06	47.00
IUUC-Smo-108684	Selaginella moellendorffii	31.64	7.00e-31	127.00
IUUC-Sit-109872	Setaria italica	33.74	2.00e-41	162.00
IUUC-Sly-110931	Solanum lycopersicum	30.88	1.00e-42	167.00
IUUC-Stu-112216	Solanum tuberosum	31.44	3.00e-42	165.00
IUUC-Sar-113489	Sorex araneus	97.83	0.00e+00	682.00
IUUC-Sbi-114704	Sorghum bicolor	32.08	2.00e-41	162.00
IUUC-Tru-117832	Takifugu rubripes	94.04	0.00e+00	659.00
IUUC-Tsy-118969	Tarsius syrichta	92.68	0.00e+00	637.00
IUUC-Tni-120221	Tetraodon nigroviridis	94.04	0.00e+00	659.00
IUUC-Tca-121715	Theobroma cacao	31.09	2.00e-44	172.00
IUUC-Tae-122976	Triticum aestivum	31.48	4.00e-41	161.00
IUUC-Tbe-127298	Tupaia belangeri	97.29	0.00e+00	669.00
IUUC-Ttr-128952	Tursiops truncatus	97.56	0.00e+00	680.00
IUUC-Vda-129835	Verticillium dahliae	42.00	6.00e-07	49.30
IUUC-Vpa-130735	Vicugna pacos	91.87	4.00e-176	610.00
IUUC-Vvi-130854	Vitis vinifera	31.29	1.00e-31	130.00
IUUC-Xtr-132806	Xenopus tropicalis	95.96	0.00e+00	668.00
IUUC-Xma-133544	Xiphophorus maculatus	97.85	8.00e-174	602.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence