iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072138

Ensembl Protein ID

ENSONIP00000005094.1

UniProt Accession

I3J8A4; I3J8A4_ORENI

Genbank Protein ID

ENSONIP00000005094

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01021376

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000004042.1	ENSONIT00000005098.1	ENSONIP00000005094.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.90e-19	69.6	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.70e-07	28.3	147	175

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaa+S++F+a+f+++l+es     v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGDRSFPCHRAVLAACSRYFEAMFSGGLRESL-DTDVNFRDsIHPEVLELLLDFAYSSRVIINE 114
           7************************************9.999****99******************9987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
           +Nclg++ ++d+++c +L++   +++l h
   Q: 147  SNCLGMMLLSDAHQCKRLYELSWRMCLVH 175
           8******************9999988877 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MSVTVHENRK SRTSTGSMNI SLFHKPSHPD SVLTHLNTMR KQCMFTDVTL WAGDRSFPCH 60
RAVLAACSRY FEAMFSGGLR ESLDTDVNFR DSIHPEVLEL LLDFAYSSRV IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTGTTTCC ACGTCTCCTT TATCGGGCTG TGAGACATGA GGCTCTAATG TTAAAATGAA 60
TCCACTTTAA AGTTTCACAG CTCTAATGCG GTTTCATCAC TGAGAGTGCA CGCAGTGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	85.23	0.00e+00	1079.00
IUUC-Apl-003543	Anas platyrhynchos	85.76	0.00e+00	1053.00
IUUC-Aca-004729	Anolis carolinensis	83.87	0.00e+00	1038.00
IUUC-Ame-011020	Astyanax mexicanus	94.06	0.00e+00	1133.00
IUUC-Bta-012955	Bos taurus	84.38	0.00e+00	1070.00
IUUC-Cja-018839	Callithrix jacchus	84.38	0.00e+00	1070.00
IUUC-Cfa-020224	Canis familiaris	85.23	0.00e+00	1078.00
IUUC-Cpo-021593	Cavia porcellus	83.87	0.00e+00	1024.00
IUUC-Csa-023276	Chlorocebus sabaeus	84.89	0.00e+00	1076.00
IUUC-Dre-028053	Danio rerio	93.72	0.00e+00	1101.00
IUUC-Dno-029287	Dasypus novemcinctus	83.70	0.00e+00	1056.00
IUUC-Fca-035897	Felis catus	85.40	0.00e+00	1080.00
IUUC-Fal-037036	Ficedula albicollis	86.42	0.00e+00	1064.00
IUUC-Gmo-039345	Gadus morhua	94.57	0.00e+00	1097.00
IUUC-Gga-040404	Gallus gallus	86.08	0.00e+00	1063.00
IUUC-Gac-042447	Gasterosteus aculeatus	96.60	0.00e+00	1130.00
IUUC-Ggo-045060	Gorilla gorilla	84.89	0.00e+00	1078.00
IUUC-Hsa-046494	Homo sapiens	84.89	0.00e+00	1077.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	85.23	0.00e+00	1076.00
IUUC-Lch-050211	Latimeria chalumnae	88.95	0.00e+00	1090.00
IUUC-Loc-052578	Lepisosteus oculatus	92.70	0.00e+00	1123.00
IUUC-Laf-053498	Loxodonta africana	85.06	0.00e+00	1033.00
IUUC-Mcc-055033	Macaca mulatta	84.89	0.00e+00	1077.00
IUUC-Meu-056893	Macropus eugenii	86.93	0.00e+00	1094.00
IUUC-Mor-057181	Magnaporthe oryzae	25.74	2.00e-12	66.60
IUUC-Mga-060025	Meleagris gallopavo	86.25	0.00e+00	1063.00
IUUC-Mmr-060658	Microcebus murinus	85.06	0.00e+00	1079.00
IUUC-Mdo-062667	Monodelphis domestica	86.93	0.00e+00	1095.00
IUUC-Mmu-063125	Mus musculus	83.19	0.00e+00	1023.00
IUUC-Mpu-066209	Mustela putorius furo	85.06	0.00e+00	1078.00
IUUC-Mlu-068237	Myotis lucifugus	83.70	0.00e+00	1036.00
IUUC-Nle-069454	Nomascus leucogenys	84.73	0.00e+00	1063.00
IUUC-Oan-073320	Ornithorhynchus anatinus	81.83	0.00e+00	1029.00
IUUC-Ocu-073765	Oryctolagus cuniculus	81.49	0.00e+00	1004.00
IUUC-Oga-088002	Otolemur garnettii	84.55	0.00e+00	1063.00
IUUC-Oar-089481	Ovis aries	84.21	0.00e+00	1068.00
IUUC-Ptr-091200	Pan troglodytes	84.72	0.00e+00	1071.00
IUUC-Psi-093884	Pelodiscus sinensis	86.76	0.00e+00	1062.00
IUUC-Pva-102321	Pteropus vampyrus	84.21	0.00e+00	1066.00
IUUC-Rno-104835	Rattus norvegicus	83.02	0.00e+00	1024.00
IUUC-Sha-107528	Sarcophilus harrisii	86.59	0.00e+00	1092.00
IUUC-Ssc-116161	Sus scrofa	85.40	0.00e+00	1080.00
IUUC-Tgu-116569	Taeniopygia guttata	86.25	0.00e+00	1061.00
IUUC-Tni-120525	Tetraodon nigroviridis	84.94	0.00e+00	979.00
IUUC-Ttr-129297	Tursiops truncatus	85.06	0.00e+00	1074.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence