iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065890

Ensembl Protein ID

ENSMPUP00000007131.1

UniProt Accession

M3Y727; M3Y727_MUSPF

Genbank Protein ID

ENSMPUP00000007131

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01061512

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007189.1	ENSMPUT00000007250.1	ENSMPUP00000007131.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	29.85	2.00e-46	184.00	IUUC-Dme-031819
E3 activity/RING/RING	88.60	0.00e+00	979.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MSTYSTFPSG VPVSERSLAR AGFYYTGVND KVKCFCCGLM LDNWKPGDNP VEKHKQLYPS 60
CSFIHSLVTL TSRDSTFKTT SPMRNSSPHS LCPTSEHGGS FSGSRADLAP SPANPRAVED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCGCCCGG GACTTCGCGT TGGTGAGCGG CTGACGCCTG TCGCTCCTGG TCACCTGCGG 60
CGCGCACGCG GCGCTCCTGC CCGCTGACCG CCGGGCCGAG TCGCCAGGGG AGGGGGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:0070266--P:necroptotic process
GO:0043066--P:negative regulation of apoptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000162	Aegilops tauschii	24.48	5.00e-08	52.40
IUUC-Aml-002369	Ailuropoda melanoleuca	92.83	0.00e+00	1064.00
IUUC-Atr-002499	Amborella trichopoda	44.64	5.00e-12	65.10
IUUC-Apl-003549	Anas platyrhynchos	70.59	0.00e+00	810.00
IUUC-Aca-004515	Anolis carolinensis	67.42	0.00e+00	760.00
IUUC-Bta-012450	Bos taurus	85.53	0.00e+00	949.00
IUUC-Cel-018418	Caenorhabditis elegans	40.00	4.00e-08	52.80
IUUC-Cja-018895	Callithrix jacchus	88.27	0.00e+00	979.00
IUUC-Cfa-020419	Canis familiaris	92.46	0.00e+00	1050.00
IUUC-Cpo-022048	Cavia porcellus	85.96	0.00e+00	964.00
IUUC-Csa-024159	Chlorocebus sabaeus	80.94	0.00e+00	907.00
IUUC-Cho-024277	Choloepus hoffmanni	83.86	0.00e+00	931.00
IUUC-Cin-025521	Ciona intestinalis	29.86	2.00e-73	270.00
IUUC-Dre-028647	Danio rerio	55.09	3.00e-176	611.00
IUUC-Dno-029509	Dasypus novemcinctus	80.74	0.00e+00	916.00
IUUC-Dor-030796	Dipodomys ordii	70.28	1.00e-94	340.00
IUUC-Dme-031819	Drosophila melanogaster	29.62	4.00e-67	248.00
IUUC-Ete-032768	Echinops telfairi	66.43	0.00e+00	696.00
IUUC-Eca-033393	Equus caballus	90.54	0.00e+00	1019.00
IUUC-Eeu-035114	Erinaceus europaeus	83.51	0.00e+00	940.00
IUUC-Fca-036034	Felis catus	89.47	0.00e+00	1003.00
IUUC-Fal-037656	Ficedula albicollis	69.72	0.00e+00	800.00
IUUC-Gga-040601	Gallus gallus	71.28	0.00e+00	817.00
IUUC-Ggo-044857	Gorilla gorilla	88.25	0.00e+00	981.00
IUUC-Hsa-045769	Homo sapiens	88.60	0.00e+00	985.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	86.71	0.00e+00	983.00
IUUC-Lch-050259	Latimeria chalumnae	61.82	0.00e+00	690.00
IUUC-Laf-053449	Loxodonta africana	85.84	0.00e+00	951.00
IUUC-Mcc-055282	Macaca mulatta	80.77	0.00e+00	906.00
IUUC-Meu-056241	Macropus eugenii	65.80	0.00e+00	663.00
IUUC-Mor-057252	Magnaporthe oryzae	33.33	6.00e-16	79.70
IUUC-Mga-059947	Meleagris gallopavo	71.28	0.00e+00	816.00
IUUC-Mdo-062352	Monodelphis domestica	77.58	0.00e+00	867.00
IUUC-Mmu-064340	Mus musculus	82.34	0.00e+00	916.00
IUUC-Mac-065489	Musa acuminata	36.73	4.00e-08	51.60
IUUC-Mlu-068077	Myotis lucifugus	88.64	0.00e+00	1032.00
IUUC-Nle-070081	Nomascus leucogenys	87.37	0.00e+00	983.00
IUUC-Opr-070561	Ochotona princeps	82.63	0.00e+00	908.00
IUUC-Oan-073604	Ornithorhynchus anatinus	74.61	0.00e+00	838.00
IUUC-Ocu-073963	Oryctolagus cuniculus	86.14	0.00e+00	964.00
IUUC-Oga-087976	Otolemur garnettii	88.77	0.00e+00	1000.00
IUUC-Oar-090097	Ovis aries	87.30	0.00e+00	999.00
IUUC-Ptr-091137	Pan troglodytes	88.42	0.00e+00	984.00
IUUC-Pan-092673	Papio anubis	89.30	0.00e+00	997.00
IUUC-Psi-092992	Pelodiscus sinensis	70.64	0.00e+00	806.00
IUUC-Ppa-095167	Physcomitrella patens	42.86	3.00e-11	62.40
IUUC-Pab-098734	Pongo abelii	88.95	0.00e+00	987.00
IUUC-Pop-098944	Populus trichocarpa	42.59	7.00e-10	58.20
IUUC-Pca-100708	Procavia capensis	73.24	5.00e-175	607.00
IUUC-Pva-102788	Pteropus vampyrus	89.82	0.00e+00	999.00
IUUC-Rno-105026	Rattus norvegicus	78.60	0.00e+00	883.00
IUUC-Sha-107229	Sarcophilus harrisii	71.90	0.00e+00	797.00
IUUC-Stu-112233	Solanum tuberosum	45.83	8.00e-09	54.30
IUUC-Ssc-115804	Sus scrofa	85.34	0.00e+00	956.00
IUUC-Tgu-116931	Taeniopygia guttata	70.24	0.00e+00	822.00
IUUC-Tsy-118958	Tarsius syrichta	64.88	0.00e+00	655.00
IUUC-Tbe-127523	Tupaia belangeri	88.07	0.00e+00	998.00
IUUC-Ttr-128954	Tursiops truncatus	85.64	0.00e+00	955.00
IUUC-Vpa-130441	Vicugna pacos	87.89	0.00e+00	991.00
IUUC-Xtr-132031	Xenopus tropicalis	57.14	0.00e+00	627.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence