iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/Other	E3 activity/Other	19363481

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids. This has a subsequent role in the maintenance of chromosome structure. May work in conjunction with the Smc5-Smc6 complex.

Protein Sequence
(Fasta)

MDNLDEDDLA FFSKPIKKPP LNYAKQLIAS SSDSEEESEL DTNKQALEHI NAQKNITHNE 60
NKSAEPLSRQ STILDADEGN QDVSDTTPNA CLNEGRHSPK SAISCVTQPV SPVYNTRAAA 120

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Nucleotide Sequence
(Fasta)

TGGAACCACC GTAATTGCTA AAACTCGCCA AATGGACAAC CTAGATGAAG ATGACTTAGC 60
ATTCTTCTCA AAGCCTATTA AAAAGCCTCC ATTAAACTAT GCCAAGCAAT TAATAGCCTC 120

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Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0233--DNA recombination
KW-0234--DNA repair
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

Pfam

PF11976--Rad60-SLD

Gene Ontology

GO:0005634--C:nucleus
GO:0005940--C:septin ring
GO:0031386--F:protein tag
GO:0000724--P:double-strand break repair via homologous recombination
GO:0000070--P:mitotic sister chromatid segregation
GO:0016925--P:protein sumoylation
GO:0031297--P:replication fork processing

KEGG

spo:SPBC1921.02

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002836	Amborella trichopoda	63.16	3.80e-01	28.50
IUUC-Aly-006354	Arabidopsis lyrata	43.33	7.00e-03	31.60
IUUC-Ath-007123	Arabidopsis thaliana	35.59	1.90e-02	31.60
IUUC-Acl-008071	Aspergillus clavatus	20.86	3.00e-08	50.80
IUUC-Afu-008995	Aspergillus fumigatus	21.23	6.00e-04	36.60
IUUC-Ani-009429	Aspergillus nidulans	22.22	8.00e-07	46.20
IUUC-Ate-010268	Aspergillus terreus	22.99	1.00e-05	42.00
IUUC-Bci-013952	Botrytis cinerea	20.42	2.00e-03	35.40
IUUC-Bra-017505	Brassica rapa	36.21	2.00e-02	31.60
IUUC-Cre-023011	Chlamydomonas reinhardtii	36.36	1.20e-02	32.30
IUUC-Dse-031278	Dothistroma septosporum	33.33	2.00e-06	45.10
IUUC-Ete-032853	Echinops telfairi	20.78	3.80e-01	27.70
IUUC-Fox-037848	Fusarium oxysporum	21.03	1.00e-05	42.40
IUUC-Lpe-051113	Leersia perrieri	31.25	1.60e-02	32.00
IUUC-Lma-053265	Leptosphaeria maculans	25.00	5.00e-08	50.10
IUUC-Mor-057122	Magnaporthe oryzae	21.79	2.30e-02	31.60
IUUC-Mla-059059	Melampsora laricipopulina	28.40	1.80e-02	32.70
IUUC-Nfi-068292	Neosartorya fischeri	21.79	3.00e-04	37.40
IUUC-Opr-071078	Ochotona princeps	30.91	4.70e-02	30.80
IUUC-Oba-074971	Oryza barthii	29.47	2.00e-03	33.50
IUUC-Oin-079571	Oryza indica	29.47	4.00e-03	33.90
IUUC-Olo-080607	Oryza longistaminata	27.66	1.60e-02	32.00
IUUC-Ome-081891	Oryza meridionalis	28.42	1.10e-02	31.20
IUUC-Oni-083071	Oryza nivara	29.47	4.00e-03	33.90
IUUC-Oru-085245	Oryza rufipogon	29.47	4.00e-03	33.90
IUUC-Osa-085845	Oryza sativa	30.21	3.00e-04	37.70
IUUC-Pno-095000	Phaeosphaeria nodorum	20.51	5.00e-03	33.90
IUUC-Pte-104103	Pyrenophora teres	26.87	2.00e-07	48.10
IUUC-Pyt-104630	Pyrenophora triticirepentis	27.86	2.00e-08	52.00
IUUC-Sja-107802	Schizosaccharomyces japonicus	51.03	4.00e-53	199.00
IUUC-Tsy-119099	Tarsius syrichta	38.18	4.90e-01	28.10
IUUC-Tca-121822	Theobroma cacao	22.45	1.10e-02	32.70
IUUC-Tre-122102	Trichoderma reesei	18.88	2.10e-02	32.00
IUUC-Tur-125960	Triticum urartu	28.18	3.00e-03	31.60
IUUC-Vda-129962	Verticillium dahliae	29.17	2.50e-02	31.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence