iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Uma-129595

Ensembl Protein ID

KIS66696

UniProt Accession

Q4P555; A0A0D1DS35; PPIL2_USTMA

Genbank Protein ID

KIS66696.1

Protein Name

Peptidyl-prolyl cis-trans isomerase-like 2; Cyclophilin-60; Cyclophilin-like protein Cyp-60; RING-type E3 ubiquitin transferase isomerase-like 2; Rotamase

Genbank Nucleotide ID

CM003156

Gene Name

CYP8; UMAG_04758

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
UMAG_04758	KIS66696	KIS66696

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.90e-08	32.8	41	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
            ++ +C+Is+++ + Pv++p +Gi ++ +++  +l++  + +Pvt+++++ +++v  + +++   ++++ 
   Q: 41   VSYDCCAISFQPWSVPVCSPdCGIAFELTNLIPFLRKFSSVHPVTGKRFDLDNVVRLNLHKNQHGRFHDP 110
           6789****************************************************99999999888876 PP

Organism

Ustilago maydis

Functional Description
(View)

May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.

Protein Sequence
(Fasta)

MGHGKSDRPF LSAAEHSGVY GAHSASSGKA GALEQASFHP VSYDCCAISF QPWSVPVCSP 60
DCGIAFELTN LIPFLRKFSS VHPVTGKRFD LDNVVRLNLH KNQHGRFHDP VSFKEFGQHS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCCACG GCAAATCGGA TCGACCCTTC CTTAGCGCCG CCGAGCACTC TGGCGTCTAC 60
GGCGCCCACT CGGCCTCGTC TGGTAAAGCT GGCGCACTGG AACAAGCCAG CTTCCATCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0413--Isomerase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0697--Rotamase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR029000--Cyclophilin-like_dom
IPR024936--Cyclophilin-type_PPIase
IPR020892--Cyclophilin-type_PPIase_CS
IPR002130--Cyclophilin-type_PPIase_dom
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00170--CSA_PPIASE_1
PS50072--CSA_PPIASE_2
PS51698--U_BOX

Pfam

PF00160--Pro_isomerase

PRINTS

PR00153--CSAPPISMRASE

Gene Ontology

GO:0005634--C:nucleus
GO:0003755--F:peptidyl-prolyl cis-trans isomerase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006457--P:protein folding

KEGG

uma:UMAG_04758

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000982	Aegilops tauschii	47.57	3.00e-36	144.00
IUUC-Aml-002351	Ailuropoda melanoleuca	38.32	7.00e-91	326.00
IUUC-Atr-002724	Amborella trichopoda	48.29	3.00e-41	161.00
IUUC-Apl-003515	Anas platyrhynchos	43.19	1.00e-86	311.00
IUUC-Aca-004802	Anolis carolinensis	42.54	1.00e-94	338.00
IUUC-Aly-005928	Arabidopsis lyrata	35.24	2.00e-37	149.00
IUUC-Ath-007574	Arabidopsis thaliana	35.24	5.00e-37	147.00
IUUC-Acl-008183	Aspergillus clavatus	41.44	1.00e-95	341.00
IUUC-Afl-008382	Aspergillus flavus	42.21	1.00e-101	362.00
IUUC-Afu-008952	Aspergillus fumigatus	42.83	2.00e-98	350.00
IUUC-Ani-009146	Aspergillus nidulans	40.54	9.00e-98	348.00
IUUC-Ang-009743	Aspergillus niger	44.64	1.00e-101	361.00
IUUC-Aor-010027	Aspergillus oryzae	42.21	6.00e-102	363.00
IUUC-Ate-010569	Aspergillus terreus	42.98	8.00e-100	355.00
IUUC-Ame-010783	Astyanax mexicanus	38.75	8.00e-95	339.00
IUUC-Bgr-012172	Blumeria graminis	33.72	2.00e-59	221.00
IUUC-Bta-012459	Bos taurus	35.67	1.00e-86	311.00
IUUC-Bci-013693	Botrytis cinerea	36.47	4.00e-83	300.00
IUUC-Bdi-014623	Brachypodium distachyon	47.80	2.00e-40	159.00
IUUC-Bol-015781	Brassica oleracea	48.29	2.00e-40	158.00
IUUC-Bra-016624	Brassica rapa	48.29	2.00e-40	159.00
IUUC-Cel-018328	Caenorhabditis elegans	39.44	1.00e-75	275.00
IUUC-Cja-019427	Callithrix jacchus	39.96	6.00e-90	323.00
IUUC-Cfa-020829	Canis familiaris	37.59	2.00e-93	334.00
IUUC-Cpo-022189	Cavia porcellus	35.85	2.00e-90	324.00
IUUC-Cre-022723	Chlamydomonas reinhardtii	53.22	9.00e-47	179.00
IUUC-Csa-024212	Chlorocebus sabaeus	37.04	2.00e-91	328.00
IUUC-Cin-025720	Ciona intestinalis	40.93	1.00e-99	355.00
IUUC-Csv-026137	Ciona savignyi	40.97	1.00e-91	328.00
IUUC-Cgl-026532	Colletotrichum gloeosporioides	37.44	2.00e-85	307.00
IUUC-Cne-026830	Cryptococcus neoformans	43.97	3.00e-117	414.00
IUUC-Dre-028561	Danio rerio	39.56	1.00e-85	308.00
IUUC-Dno-029029	Dasypus novemcinctus	33.12	2.00e-79	288.00
IUUC-Dor-030683	Dipodomys ordii	49.67	4.00e-28	117.00
IUUC-Dse-031506	Dothistroma septosporum	39.24	1.00e-89	322.00
IUUC-Dme-032058	Drosophila melanogaster	39.17	2.00e-84	304.00
IUUC-Ete-033157	Echinops telfairi	32.01	8.00e-56	209.00
IUUC-Eca-034176	Equus caballus	44.16	2.00e-31	129.00
IUUC-Eeu-034470	Erinaceus europaeus	35.46	1.00e-52	199.00
IUUC-Fca-036571	Felis catus	37.44	2.00e-91	328.00
IUUC-Fal-037613	Ficedula albicollis	40.89	8.00e-93	332.00
IUUC-Fox-037795	Fusarium oxysporum	39.29	2.00e-92	331.00
IUUC-Fso-038213	Fusarium solani	41.79	3.00e-92	330.00
IUUC-Gmo-039609	Gadus morhua	38.77	1.00e-79	288.00
IUUC-Ggr-039825	Gaeumannomyces graminis	38.71	2.00e-91	328.00
IUUC-Gga-041191	Gallus gallus	41.06	2.00e-93	334.00
IUUC-Gac-041524	Gasterosteus aculeatus	41.01	2.00e-87	314.00
IUUC-Gma-042936	Glycine max	45.54	1.00e-38	152.00
IUUC-Ggo-045352	Gorilla gorilla	40.59	6.00e-91	326.00
IUUC-Hsa-045709	Homo sapiens	40.59	7.00e-91	325.00
IUUC-Hvu-047058	Hordeum vulgare	47.80	5.00e-40	157.00
IUUC-Itr-048483	Ictidomys tridecemlineatus	41.27	1.00e-89	322.00
IUUC-Lch-049681	Latimeria chalumnae	41.63	6.00e-86	309.00
IUUC-Lpe-050799	Leersia perrieri	48.29	2.00e-41	162.00
IUUC-Loc-052566	Lepisosteus oculatus	50.00	3.00e-42	164.00
IUUC-Lma-053028	Leptosphaeria maculans	41.51	4.00e-90	323.00
IUUC-Laf-054547	Loxodonta africana	40.66	9.00e-89	318.00
IUUC-Mcc-054753	Macaca mulatta	37.57	3.00e-90	323.00
IUUC-Meu-056855	Macropus eugenii	32.30	2.00e-33	134.00
IUUC-Mor-056941	Magnaporthe oryzae	38.89	4.00e-82	296.00
IUUC-Mpo-057306	Magnaporthe poae	35.90	2.00e-91	328.00
IUUC-Mtr-058349	Medicago truncatula	47.83	7.00e-37	146.00
IUUC-Mla-058842	Melampsora laricipopulina	42.81	2.00e-114	404.00
IUUC-Mga-060099	Meleagris gallopavo	39.19	3.00e-82	297.00
IUUC-Mvi-060413	Microbotryum violaceum	41.39	4.00e-108	383.00
IUUC-Mmr-061530	Microcebus murinus	36.90	2.00e-90	324.00
IUUC-Mdo-062668	Monodelphis domestica	42.38	4.00e-93	333.00
IUUC-Mmu-063871	Mus musculus	40.12	4.00e-91	327.00
IUUC-Mac-064559	Musa acuminata	46.86	1.00e-40	159.00
IUUC-Mpu-065919	Mustela putorius furo	41.54	8.00e-92	329.00
IUUC-Mlu-067846	Myotis lucifugus	35.50	2.00e-79	287.00
IUUC-Nfi-068507	Neosartorya fischeri	43.03	5.00e-95	340.00
IUUC-Ncr-068805	Neurospora crassa	38.82	1.00e-72	265.00
IUUC-Nle-070125	Nomascus leucogenys	38.40	5.00e-81	293.00
IUUC-Opr-070486	Ochotona princeps	37.42	3.00e-70	256.00
IUUC-Ont-071597	Oreochromis niloticus	42.16	1.00e-89	322.00
IUUC-Oan-072832	Ornithorhynchus anatinus	42.48	1.00e-23	105.00
IUUC-Ocu-074411	Oryctolagus cuniculus	41.10	7.00e-90	322.00
IUUC-Oba-075040	Oryza barthii	48.78	9.00e-42	162.00
IUUC-Obr-076727	Oryza brachyantha	48.78	2.00e-41	162.00
IUUC-Ogl-077605	Oryza glaberrima	48.78	9.00e-42	162.00
IUUC-Ogu-078177	Oryza glumaepatula	48.78	9.00e-42	162.00
IUUC-Oin-079549	Oryza indica	45.85	1.00e-36	146.00
IUUC-Olo-081090	Oryza longistaminata	48.78	9.00e-42	163.00
IUUC-Ome-081979	Oryza meridionalis	48.78	1.00e-41	162.00
IUUC-Oni-082819	Oryza nivara	48.78	9.00e-42	162.00
IUUC-Opu-083212	Oryza punctata	48.29	3.00e-41	161.00
IUUC-Oru-084412	Oryza rufipogon	48.78	9.00e-42	162.00
IUUC-Osa-085431	Oryza sativa	36.15	9.00e-21	90.90
IUUC-Ola-086602	Oryzias latipes	40.75	2.00e-81	294.00
IUUC-Olu-087682	Ostreococcus lucimarinus	39.36	7.00e-76	276.00
IUUC-Oga-088999	Otolemur garnettii	33.88	1.00e-78	285.00
IUUC-Oar-089338	Ovis aries	37.70	1.00e-63	235.00
IUUC-Ptr-091185	Pan troglodytes	40.59	6.00e-91	326.00
IUUC-Pan-092321	Papio anubis	36.55	1.00e-91	328.00
IUUC-Psi-094018	Pelodiscus sinensis	50.71	5.00e-49	186.00
IUUC-Pma-094111	Petromyzon marinus	39.43	2.00e-71	260.00
IUUC-Pno-094782	Phaeosphaeria nodorum	37.07	2.00e-93	334.00
IUUC-Ppa-095335	Physcomitrella patens	46.95	1.00e-41	162.00
IUUC-Pfo-097393	Poecilia formosa	41.50	4.00e-88	317.00
IUUC-Pab-098263	Pongo abelii	37.42	1.00e-77	281.00
IUUC-Pop-099316	Populus trichocarpa	37.78	5.00e-68	249.00
IUUC-Pca-100387	Procavia capensis	32.69	4.00e-26	110.00
IUUC-Ppe-101275	Prunus persica	45.41	2.00e-36	145.00
IUUC-Pva-102150	Pteropus vampyrus	37.84	7.00e-77	279.00
IUUC-Pgr-103378	Puccinia graminis	41.30	4.00e-112	396.00
IUUC-Ptt-103908	Puccinia triticina	41.29	8.00e-106	375.00
IUUC-Pte-104248	Pyrenophora teres	37.42	5.00e-92	330.00
IUUC-Pyt-104645	Pyrenophora triticirepentis	37.75	4.00e-94	337.00
IUUC-Rno-105162	Rattus norvegicus	36.77	5.00e-91	326.00
IUUC-Sha-107123	Sarcophilus harrisii	50.76	2.00e-43	168.00
IUUC-Sja-107828	Schizosaccharomyces japonicus	39.28	7.00e-91	326.00
IUUC-Spo-108368	Schizosaccharomyces pombe	37.11	1.00e-95	342.00
IUUC-Smo-109102	Selaginella moellendorffii	48.29	1.00e-42	166.00
IUUC-Sit-110821	Setaria italica	47.80	6.00e-41	160.00
IUUC-Sly-111803	Solanum lycopersicum	46.86	3.00e-40	157.00
IUUC-Stu-112730	Solanum tuberosum	46.86	4.00e-40	157.00
IUUC-Sar-113618	Sorex araneus	37.73	2.00e-86	311.00
IUUC-Sbi-114487	Sorghum bicolor	49.27	1.00e-41	162.00
IUUC-Sre-115009	Sporisorium reilianum	71.55	0.00e+00	783.00
IUUC-Ssc-115984	Sus scrofa	41.32	2.00e-89	320.00
IUUC-Tgu-117410	Taeniopygia guttata	40.84	4.00e-93	333.00
IUUC-Tru-118537	Takifugu rubripes	39.70	5.00e-85	306.00
IUUC-Tsy-119318	Tarsius syrichta	28.76	2.00e-29	122.00
IUUC-Tni-120514	Tetraodon nigroviridis	44.38	2.00e-69	254.00
IUUC-Tca-121620	Theobroma cacao	48.29	5.00e-38	150.00
IUUC-Tre-121904	Trichoderma reesei	40.45	3.00e-77	281.00
IUUC-Tvi-122585	Trichoderma virens	38.33	2.00e-80	291.00
IUUC-Tae-125342	Triticum aestivum	47.80	5.00e-40	157.00
IUUC-Tur-126759	Triticum urartu	46.05	4.00e-34	137.00
IUUC-Tme-126960	Tuber melanosporum	44.59	6.00e-102	362.00
IUUC-Tbe-128038	Tupaia belangeri	42.86	5.00e-30	124.00
IUUC-Ttr-129173	Tursiops truncatus	32.09	3.00e-59	221.00
IUUC-Vda-130012	Verticillium dahliae	36.54	2.00e-79	288.00
IUUC-Vpa-130129	Vicugna pacos	44.16	1.00e-31	129.00
IUUC-Vvi-131156	Vitis vinifera	47.83	4.00e-41	160.00
IUUC-Xtr-132807	Xenopus tropicalis	39.55	1.00e-89	322.00
IUUC-Xma-133563	Xiphophorus maculatus	42.86	1.00e-30	126.00
IUUC-Yli-134361	Yarrowia lipolytica	33.40	2.00e-51	194.00
IUUC-Zma-135759	Zea mays	48.29	1.00e-40	159.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence