iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073717

UUCD1 version

UUC-OrA-00168

Ensembl Protein ID

ENSOANP00000006641.1

UniProt Accession

F6TWZ4; F6TWZ4_ORNAN

Protein Name

Uncharacterized protein

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000004185.2	ENSOANT00000006643.2	ENSOANP00000006641.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.40e-09	36.7	256	294
UBD/Alpha-Helix/CUE	7.20e-12	45.2	371	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+++++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 256  CAICWDSMQA-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 294
           ********99.******************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+ +++q++e+FP+++y v+ ++L ++t s+e +++n+Leg 
   Q: 371  QLNAMAHQIQEMFPQVPYHVVLQDL-QLTRSVEITTDNILEGR 412
           5889*********************.***************95 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

VLVNTACCFL MLVAKLIQCV VFGPLRVSER QHLKDKFWNF IFYKFIFIFG VLNVQTVEEV 60
VMWCLWFAGL VFLHLMVQLC KDRFEYLSFS PTTPMGSHVR VLTLLIAMLL SCCGLAVVCC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGTTTCCT TTCCCCAAGC AAAATGAGAT TTGTTCTTCT CTTTTAGGTG CTGGTAAATA 60
CGGCCTGCTG CTTTTTGATG CTGGTGGCAA AACTAATCCA GTGTGTCGTG TTTGGTCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	27.16	3.00e-24	105.00
IUUC-Aml-001300	Ailuropoda melanoleuca	84.45	0.00e+00	900.00
IUUC-Atr-002892	Amborella trichopoda	30.17	2.00e-32	132.00
IUUC-Apl-003404	Anas platyrhynchos	82.32	0.00e+00	860.00
IUUC-Aca-004559	Anolis carolinensis	81.42	0.00e+00	795.00
IUUC-Aly-005440	Arabidopsis lyrata	28.06	9.00e-33	134.00
IUUC-Ath-006702	Arabidopsis thaliana	30.42	2.00e-36	146.00
IUUC-Ago-007894	Ashbya gossypii	26.34	6.00e-13	68.60
IUUC-Acl-008041	Aspergillus clavatus	21.45	5.00e-15	75.90
IUUC-Afl-008427	Aspergillus flavus	31.33	9.00e-15	75.10
IUUC-Afu-009023	Aspergillus fumigatus	28.72	1.00e-16	81.30
IUUC-Ani-009133	Aspergillus nidulans	22.19	3.00e-15	76.30
IUUC-Ang-009612	Aspergillus niger	24.30	7.00e-17	82.00
IUUC-Aor-010045	Aspergillus oryzae	31.33	8.00e-15	75.10
IUUC-Ate-010533	Aspergillus terreus	29.33	2.00e-14	73.90
IUUC-Ame-011640	Astyanax mexicanus	73.17	0.00e+00	707.00
IUUC-Bgr-012122	Blumeria graminis	25.54	7.00e-11	62.40
IUUC-Bta-012980	Bos taurus	85.00	0.00e+00	895.00
IUUC-Bci-013675	Botrytis cinerea	29.94	2.00e-11	64.30
IUUC-Bdi-015070	Brachypodium distachyon	34.36	1.00e-35	144.00
IUUC-Bol-015593	Brassica oleracea	32.04	2.00e-35	143.00
IUUC-Bra-017516	Brassica rapa	32.75	6.00e-36	144.00
IUUC-Cel-018598	Caenorhabditis elegans	24.52	2.00e-30	126.00
IUUC-Cja-019577	Callithrix jacchus	84.82	0.00e+00	899.00
IUUC-Cfa-020793	Canis familiaris	85.49	0.00e+00	881.00
IUUC-Cpo-022387	Cavia porcellus	86.07	0.00e+00	898.00
IUUC-Cre-022743	Chlamydomonas reinhardtii	25.65	3.00e-25	108.00
IUUC-Csa-023168	Chlorocebus sabaeus	85.36	0.00e+00	902.00
IUUC-Cho-024433	Choloepus hoffmanni	85.47	0.00e+00	724.00
IUUC-Cin-025215	Ciona intestinalis	52.78	8.00e-134	469.00
IUUC-Csv-026133	Ciona savignyi	56.13	3.00e-126	444.00
IUUC-Cne-027002	Cryptococcus neoformans	26.85	2.00e-25	110.00
IUUC-Cme-027285	Cyanidioschyzon merolae	29.58	4.00e-23	102.00
IUUC-Dre-027594	Danio rerio	82.98	0.00e+00	690.00
IUUC-Dno-029407	Dasypus novemcinctus	85.36	0.00e+00	869.00
IUUC-Dor-030961	Dipodomys ordii	85.54	0.00e+00	893.00
IUUC-Dse-031498	Dothistroma septosporum	21.64	7.00e-09	55.50
IUUC-Dme-031969	Drosophila melanogaster	27.89	4.00e-28	119.00
IUUC-Ete-032962	Echinops telfairi	77.86	0.00e+00	732.00
IUUC-Eca-033683	Equus caballus	83.60	0.00e+00	857.00
IUUC-Eeu-034515	Erinaceus europaeus	94.81	3.00e-75	275.00
IUUC-Fca-035398	Felis catus	87.17	0.00e+00	862.00
IUUC-Fal-036758	Ficedula albicollis	75.22	0.00e+00	786.00
IUUC-Fox-037902	Fusarium oxysporum	29.68	3.00e-15	76.60
IUUC-Fso-038418	Fusarium solani	29.80	4.00e-14	73.20
IUUC-Gmo-039014	Gadus morhua	80.73	0.00e+00	673.00
IUUC-Ggr-040076	Gaeumannomyces graminis	30.41	9.00e-14	72.00
IUUC-Gga-040575	Gallus gallus	82.14	0.00e+00	870.00
IUUC-Gac-041414	Gasterosteus aculeatus	81.56	0.00e+00	655.00
IUUC-Gma-044123	Glycine max	28.00	1.00e-32	134.00
IUUC-Ggo-044858	Gorilla gorilla	28.90	4.00e-27	115.00
IUUC-Hsa-046272	Homo sapiens	85.18	0.00e+00	900.00
IUUC-Hvu-047279	Hordeum vulgare	30.62	2.00e-36	145.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	85.18	0.00e+00	893.00
IUUC-Lch-050491	Latimeria chalumnae	77.84	0.00e+00	767.00
IUUC-Loc-052758	Lepisosteus oculatus	75.47	0.00e+00	721.00
IUUC-Lma-052997	Leptosphaeria maculans	24.72	5.00e-16	79.00
IUUC-Laf-053452	Loxodonta africana	85.00	0.00e+00	909.00
IUUC-Mcc-055820	Macaca mulatta	85.09	0.00e+00	882.00
IUUC-Meu-056726	Macropus eugenii	87.05	0.00e+00	759.00
IUUC-Mor-057082	Magnaporthe oryzae	30.82	3.00e-14	73.20
IUUC-Mpo-057573	Magnaporthe poae	24.45	4.00e-15	75.90
IUUC-Mtr-058601	Medicago truncatula	28.76	2.00e-33	136.00
IUUC-Mla-059168	Melampsora laricipopulina	26.93	5.00e-26	112.00
IUUC-Mga-059937	Meleagris gallopavo	82.32	0.00e+00	863.00
IUUC-Mvi-060515	Microbotryum violaceum	26.35	2.00e-22	100.00
IUUC-Mmr-060730	Microcebus murinus	85.00	0.00e+00	887.00
IUUC-Mdo-062771	Monodelphis domestica	84.81	0.00e+00	894.00
IUUC-Mmu-064219	Mus musculus	84.47	0.00e+00	888.00
IUUC-Mac-064789	Musa acuminata	28.38	3.00e-33	135.00
IUUC-Mpu-066796	Mustela putorius furo	84.91	0.00e+00	879.00
IUUC-Mlu-068189	Myotis lucifugus	82.86	0.00e+00	840.00
IUUC-Nfi-068389	Neosartorya fischeri	28.92	3.00e-16	80.10
IUUC-Ncr-068742	Neurospora crassa	30.00	1.00e-13	71.60
IUUC-Nle-069239	Nomascus leucogenys	85.36	0.00e+00	902.00
IUUC-Opr-070702	Ochotona princeps	71.58	5.00e-105	374.00
IUUC-Ont-072033	Oreochromis niloticus	73.13	0.00e+00	707.00
IUUC-Ocu-074145	Oryctolagus cuniculus	83.39	0.00e+00	887.00
IUUC-Oba-075221	Oryza barthii	28.71	1.00e-34	140.00
IUUC-Obr-076914	Oryza brachyantha	29.49	3.00e-36	145.00
IUUC-Ogl-077929	Oryza glaberrima	53.49	4.00e-11	60.10
IUUC-Ogu-078124	Oryza glumaepatula	28.71	9.00e-35	140.00
IUUC-Oin-080013	Oryza indica	28.71	1.00e-33	136.00
IUUC-Olo-080247	Oryza longistaminata	29.03	6.00e-31	127.00
IUUC-Ome-081769	Oryza meridionalis	29.26	3.00e-36	145.00
IUUC-Oni-082946	Oryza nivara	28.71	1.00e-34	140.00
IUUC-Opu-083268	Oryza punctata	27.60	2.00e-22	100.00
IUUC-Oru-085114	Oryza rufipogon	28.71	9.00e-35	140.00
IUUC-Osa-085829	Oryza sativa	29.41	1.00e-35	143.00
IUUC-Ola-087152	Oryzias latipes	69.42	0.00e+00	679.00
IUUC-Olu-087894	Ostreococcus lucimarinus	26.73	1.00e-27	116.00
IUUC-Oga-088486	Otolemur garnettii	85.36	0.00e+00	897.00
IUUC-Oar-089310	Ovis aries	85.18	0.00e+00	897.00
IUUC-Ptr-090649	Pan troglodytes	85.18	0.00e+00	900.00
IUUC-Pan-091692	Papio anubis	80.89	0.00e+00	839.00
IUUC-Psi-093064	Pelodiscus sinensis	94.72	0.00e+00	771.00
IUUC-Pma-094763	Petromyzon marinus	78.69	6.00e-98	349.00
IUUC-Pno-094883	Phaeosphaeria nodorum	24.26	6.00e-15	75.50
IUUC-Ppa-095969	Physcomitrella patens	29.60	3.00e-39	155.00
IUUC-Pfo-096810	Poecilia formosa	71.37	0.00e+00	691.00
IUUC-Pab-097859	Pongo abelii	85.09	0.00e+00	885.00
IUUC-Pop-099245	Populus trichocarpa	27.80	2.00e-31	129.00
IUUC-Pca-100344	Procavia capensis	82.77	0.00e+00	852.00
IUUC-Ppe-101829	Prunus persica	28.72	2.00e-35	143.00
IUUC-Pva-103114	Pteropus vampyrus	57.32	5.00e-142	497.00
IUUC-Pgr-103286	Puccinia graminis	24.92	7.00e-23	102.00
IUUC-Ptt-103919	Puccinia triticina	24.55	2.00e-21	96.30
IUUC-Pte-104372	Pyrenophora teres	24.35	3.00e-17	83.20
IUUC-Pyt-104456	Pyrenophora triticirepentis	23.48	5.00e-15	75.90
IUUC-Rno-105880	Rattus norvegicus	82.78	0.00e+00	863.00
IUUC-Sce-106348	Saccharomyces cerevisiae	32.00	8.00e-09	54.70
IUUC-Sha-107015	Sarcophilus harrisii	87.37	0.00e+00	868.00
IUUC-Sja-107685	Schizosaccharomyces japonicus	22.98	2.00e-18	86.30
IUUC-Spo-108308	Schizosaccharomyces pombe	22.74	4.00e-21	95.90
IUUC-Ssl-108558	Sclerotinia sclerotiorum	30.57	1.00e-11	64.70
IUUC-Smo-109664	Selaginella moellendorffii	30.97	1.00e-32	133.00
IUUC-Sit-110276	Setaria italica	29.73	3.00e-34	138.00
IUUC-Sly-111819	Solanum lycopersicum	29.89	2.00e-34	139.00
IUUC-Stu-112048	Solanum tuberosum	26.64	2.00e-29	123.00
IUUC-Sar-113397	Sorex araneus	95.15	0.00e+00	738.00
IUUC-Sbi-114192	Sorghum bicolor	30.29	6.00e-37	147.00
IUUC-Sre-115212	Sporisorium reilianum	25.97	2.00e-21	97.10
IUUC-Ssc-115988	Sus scrofa	72.76	4.00e-101	360.00
IUUC-Tgu-116717	Taeniopygia guttata	83.14	0.00e+00	824.00
IUUC-Tru-117805	Takifugu rubripes	68.08	0.00e+00	701.00
IUUC-Tsy-119442	Tarsius syrichta	78.93	0.00e+00	797.00
IUUC-Tni-119777	Tetraodon nigroviridis	66.59	3.00e-157	547.00
IUUC-Tca-121462	Theobroma cacao	29.15	1.00e-32	133.00
IUUC-Tre-122204	Trichoderma reesei	31.25	2.00e-13	70.50
IUUC-Tvi-122550	Trichoderma virens	30.56	2.00e-13	70.50
IUUC-Tae-125215	Triticum aestivum	30.45	3.00e-37	149.00
IUUC-Tur-126538	Triticum urartu	27.27	4.00e-24	105.00
IUUC-Tme-127197	Tuber melanosporum	27.15	2.00e-21	97.80
IUUC-Tbe-127322	Tupaia belangeri	65.36	5.00e-108	384.00
IUUC-Ttr-128181	Tursiops truncatus	84.29	0.00e+00	893.00
IUUC-Uma-129401	Ustilago maydis	25.00	6.00e-16	79.00
IUUC-Vda-129968	Verticillium dahliae	34.44	4.00e-14	72.80
IUUC-Vpa-130483	Vicugna pacos	83.57	0.00e+00	642.00
IUUC-Vvi-130944	Vitis vinifera	28.81	8.00e-32	130.00
IUUC-Xtr-132614	Xenopus tropicalis	75.91	0.00e+00	699.00
IUUC-Xma-133943	Xiphophorus maculatus	71.18	0.00e+00	688.00
IUUC-Yli-134552	Yarrowia lipolytica	36.25	5.00e-11	62.00
IUUC-Zma-135530	Zea mays	33.62	2.00e-35	143.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence