iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	21347703

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.37	11.7	21	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 102  lldrlpeeilveilklldkeellraarvcrrwqelas 138
           +++ +p ++++ei+++ + +++ r+++v++ w  + +
   Q: 21   NFEPIPIDLVIEIFSRSPVKSIARCRCVSKLWASILR 57
           56789***************************98776 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Negative regulator of guard cell abscisic acid (ABA) signaling, especially during drought stress.

Protein Sequence
(Fasta)

MKSRRQNVSV ARQTILGRDE NFEPIPIDLV IEIFSRSPVK SIARCRCVSK LWASILRLPY 60
FTELYLTKSC ARPRLLFACQ KHRELFFFST PQPHNPNESS SPLAASFHMK IPFDGRFNII 120

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Nucleotide Sequence
(Fasta)

CAAAAGAATT TGATTACTGC AACATGAAAT CACGGCGACA GAATGTGTCC GTGGCTCGAC 60
AAACCATCCT TGGACGCGAC GAAAACTTTG AACCAATCCC AATTGATCTC GTTATCGAGA 120

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Sequence Source

Ensembl

Keyword

KW-0938--Abscisic acid signaling pathway
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR013187--F-box-assoc_dom_typ3
IPR017451--F-box-assoc_interact_dom
IPR001810--F-box_dom

Pfam

PF00646--F-box
PF08268--FBA_3

SMART

SM00256--FBOX

Gene Ontology

GO:0009738--P:abscisic acid-activated signaling pathway
GO:0042631--P:cellular response to water deprivation
GO:0009788--P:negative regulation of abscisic acid-activated signaling pathway
GO:0016567--P:protein ubiquitination
GO:0010119--P:regulation of stomatal movement
GO:0009737--P:response to abscisic acid
GO:0009414--P:response to water deprivation
GO:0010118--P:stomatal movement

KEGG

ath:AT2G31470

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000141	Aegilops tauschii	21.28	5.00e-08	51.60
IUUC-Aca-004514	Anolis carolinensis	33.33	1.50e-02	34.30
IUUC-Aly-006099	Arabidopsis lyrata	52.30	2.00e-99	355.00
IUUC-Bta-013465	Bos taurus	25.88	7.00e-02	30.80
IUUC-Bdi-014737	Brachypodium distachyon	25.61	3.00e-10	60.10
IUUC-Bol-016117	Brassica oleracea	51.19	1.00e-96	345.00
IUUC-Bra-017514	Brassica rapa	53.06	5.00e-107	380.00
IUUC-Cgl-026389	Colletotrichum gloeosporioides	27.38	2.80e-02	33.10
IUUC-Dre-028025	Danio rerio	36.51	4.10e-02	32.30
IUUC-Fso-038435	Fusarium solani	40.54	2.30e+00	27.30
IUUC-Hvu-047063	Hordeum vulgare	25.18	8.00e-08	50.80
IUUC-Lpe-051557	Leersia perrieri	22.51	2.00e-05	45.80
IUUC-Loc-052945	Lepisosteus oculatus	22.22	4.00e-02	33.50
IUUC-Mpo-057537	Magnaporthe poae	37.14	5.60e-02	31.60
IUUC-Mpu-065798	Mustela putorius furo	32.35	3.00e-03	34.70
IUUC-Ont-072665	Oreochromis niloticus	30.34	4.00e-03	34.70
IUUC-Ocu-073784	Oryctolagus cuniculus	36.73	1.10e-01	29.30
IUUC-Ogu-078155	Oryza glumaepatula	23.92	2.00e-10	61.20
IUUC-Ome-081354	Oryza meridionalis	26.77	4.00e-14	72.80
IUUC-Pop-098871	Populus trichocarpa	27.61	8.00e-27	114.00
IUUC-Pva-103073	Pteropus vampyrus	29.41	8.60e-02	30.40
IUUC-Smo-108920	Selaginella moellendorffii	25.90	9.00e-10	57.40
IUUC-Sit-109947	Setaria italica	26.70	2.00e-09	57.80
IUUC-Sbi-113907	Sorghum bicolor	25.70	8.00e-11	60.50
IUUC-Ssc-115245	Sus scrofa	31.67	5.20e-02	30.40
IUUC-Tre-122056	Trichoderma reesei	28.57	2.00e-01	30.40
IUUC-Tae-125922	Triticum aestivum	24.44	1.00e-05	44.70

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence