iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/GAT	GAT	17494868

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/GAT	2.30e-45	152.2	192	316

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/GAT

   S: 1    deeksklLerLlkskkPeDLreAnkLikelvkededkaekikklis.eleevksnvkllnemlselspegeepednellqelyetckaarpkllklieeeed 101
           +++++++Le+Ll+s+kP+DL+eAnkL+k+++++++d+++++k++i+ el+++k++++l+neml+     +e + +ne++qely ++k+a+pk++klieee+d
   Q: 192  ERAQAAKLEELLRSGKPDDLKEANKLMKIMAGFKDDTKVAVKQAINnELNKLKRKADLFNEMLT---SADEPDLENEAIQELYGDLKSAQPKFKKLIEEERD 290
           689*************************************************************...5555559**************************** PP
   S: 102  ndellaellkanDelnqvlnkykqlk 127
           +d+l+++l k+nD ++q+l++yk++k
   Q: 291  DDALVSNLSKFNDLVIQLLKRYKSIK 316
           ***********************986 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Present with 656 molecules/cell in log phase SD medium.

Protein Sequence
(Fasta)

MPQRIELTSE PVRKPRSTES SLLRKIQRAC RSTLPEPDLG LNLDVADYIN SKQGATPREA 60
VLAIEKLVNN GDTQAAVFAL SLLDVLVKNC GYSIHLQISR KEFLNDLVKR FPEQPPLRYS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCACAAA GAATTGAGCT TACCTCCGAA CCAGTCAGAA AACCGCGGTC TACTGAGAGC 60
TCACTACTCA GAAAGATACA AAGAGCGTGT AGATCCACAT TGCCTGAACC AGATTTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0333--Golgi apparatus
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR008152--Clathrin_a/b/g-adaptin_app_Ig
IPR008153--Clathrin_g-adaptin_app
IPR013041--Coatomer/clathrin_app_Ig-like
IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR002014--VHS_dom

PROSITE

PS50180--GAE
PS50909--GAT
PS50179--VHS

Pfam

PF02883--Alpha_adaptinC2
PF03127--GAT
PF00790--VHS

SMART

SM00809--Alpha_adaptinC2
SM00288--VHS

Gene Ontology

GO:0030131--C:clathrin adaptor complex
GO:0005829--C:cytosol
GO:0005802--C:trans-Golgi network
GO:0043130--F:ubiquitin binding
GO:0006895--P:Golgi to endosome transport
GO:0006896--P:Golgi to vacuole transport
GO:0043328--P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

KEGG

sce:YDR358W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006534	Arabidopsis lyrata	30.50	1.00e-14	72.40
IUUC-Ath-007264	Arabidopsis thaliana	22.18	2.00e-10	58.90
IUUC-Bol-015614	Brassica oleracea	23.78	6.00e-15	73.90
IUUC-Bra-016712	Brassica rapa	24.16	5.00e-15	73.90
IUUC-Cre-022771	Chlamydomonas reinhardtii	25.44	6.00e-08	48.90
IUUC-Dre-027724	Danio rerio	25.96	3.00e-19	87.40
IUUC-Gmo-039118	Gadus morhua	27.78	1.00e-21	96.30
IUUC-Hvu-047560	Hordeum vulgare	23.33	6.00e-13	66.60
IUUC-Lpe-051031	Leersia perrieri	24.01	2.00e-17	82.00
IUUC-Mac-064432	Musa acuminata	24.53	2.00e-14	72.40
IUUC-Ome-081173	Oryza meridionalis	23.83	3.00e-15	74.70
IUUC-Opu-083866	Oryza punctata	24.34	5.00e-17	80.90
IUUC-Ola-087214	Oryzias latipes	26.98	8.00e-19	87.00
IUUC-Olu-087840	Ostreococcus lucimarinus	23.94	2.00e-05	42.00
IUUC-Pma-094514	Petromyzon marinus	24.46	3.00e-13	67.00
IUUC-Ppe-101544	Prunus persica	23.23	2.00e-15	75.50
IUUC-Sja-107801	Schizosaccharomyces japonicus	36.60	8.00e-81	292.00
IUUC-Sly-111006	Solanum lycopersicum	22.54	6.00e-18	84.00
IUUC-Stu-112728	Solanum tuberosum	26.56	6.00e-05	39.70
IUUC-Tca-121503	Theobroma cacao	23.65	1.00e-13	69.70
IUUC-Tur-126261	Triticum urartu	25.00	3.00e-11	62.00
IUUC-Xma-133985	Xiphophorus maculatus	26.44	2.00e-16	77.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence