iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000935

Ensembl Protein ID

EMT02198

UniProt Accession

R7W087; R7W087_AEGTA

Genbank Protein ID

EMT02198.1

Protein Name

E3 ubiquitin-protein ligase UPL4

Genbank Nucleotide ID

KD629479

Gene Name

F775_08685

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_08685	EMT02198	EMT02198

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.80e-88	296.5	977	1326

Active Site

Position(s)	Description	Evidence
1313	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglf...lysendketlqpnpdsglknp.................ehlklFeflGrllgkalqdg 85
           + leve+++E g++l G+t ef++l+s+e+q++ lg++   l  e ++++ ++ + + + ++                 e+ + F++lG++l+ka+ dg
   Q: 977  ALLEVEYEEEVGTGL-GPTMEFYTLISHEFQKSGLGMWrgeLPCEAGTNNAHIGSRTVVAPNglfprpwsasvdcasfsEVNRRFHLLGQVLAKAIKDG 1074
           5689***********.**********************887555667778899999988655999999******************************* PP
   S: 86   rlldlplsksfyklllgkklsledleevdpelykslkeikena...........esdieelgldltfsvseei.....lgetkeeeLkpgGenipVtne 168
           r+ld+p+sk+fykl+lg++l++ d++++dpel+ +l+e k++             +  ++++l  + ++ e++     ++ + e+ L ++G + +Vt e
   Q: 1075 RILDIPFSKAFYKLILGQELNIYDINSFDPELAMTLMEFKALTcqrkylescstRECQSTSDLSYRGCKIEDLvidfaVPGYPEYVLSSEGTSDNVTGE 1173
           ****************************************9987766665555422333344555555555556666699******************* PP
   S: 169  NkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLq 266
           N+eeYv+ vve+++k+gi++q+eaf +Gf++v++l+ l++F+e ele l+cGe +++d+ +l +++k+++gyt++spa+ +++e+++ef  +er+afLq
   Q: 1174 NLEEYVSFVVEATVKSGITRQLEAFESGFSQVFSLSTLRAFSEDELERLLCGEqDNWDFVKLVDHIKFDHGYTSSSPAVLNLLEIIQEFGCHERRAFLQ 1272
           *****************************************************99******************************************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirk...dasddrlPssnTCfnyLkLPeYsske 317
           F+Tgs+rlP+gG+a+l+p+l+v+rk   + +dd+lPs++TC+nyLkLP Y sk+
   Q: 1273 FITGSPRLPPGGLAALNPNLTVVRKhsnNDADDDLPSVMTCANYLKLPAYCSKD 1326
           **************************988889******************9996 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MPRAADAVVR HGLLPVLCSR LLAIEYLDVA EQCLQAFEKI SLRQPAQCLQ AGMITAVLAY 60
IDFFSASIQR VAVSAVANAC KKVPADCSQF VMDSIPMLCN LLQSEDKMVV EKVATCLISI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCACGCG CCGCCGACGC CGTCGTCCGC CACGGCCTGC TCCCCGTGCT CTGCTCCCGC 60
CTCCTCGCGA TCGAGTACCT TGATGTGGCC GAGCAGGTAA CGGAGCAGCC CTGAAAACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0436--Ligase
KW-0472--Membrane
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ats:F775_08685

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002515	Amborella trichopoda	50.54	5.00e-165	575.00
IUUC-Aly-006493	Arabidopsis lyrata	44.95	0.00e+00	1042.00
IUUC-Ath-006679	Arabidopsis thaliana	44.33	0.00e+00	1023.00
IUUC-Bdi-014101	Brachypodium distachyon	86.87	0.00e+00	2319.00
IUUC-Bol-015440	Brassica oleracea	44.08	0.00e+00	1046.00
IUUC-Bra-016648	Brassica rapa	43.86	0.00e+00	1035.00
IUUC-Gma-043952	Glycine max	46.70	0.00e+00	1130.00
IUUC-Hvu-047811	Hordeum vulgare	93.20	0.00e+00	2520.00
IUUC-Lpe-051509	Leersia perrieri	79.71	0.00e+00	2075.00
IUUC-Mtr-058626	Medicago truncatula	44.83	0.00e+00	1088.00
IUUC-Mac-065046	Musa acuminata	51.40	0.00e+00	1287.00
IUUC-Oba-075380	Oryza barthii	77.03	0.00e+00	2013.00
IUUC-Obr-076904	Oryza brachyantha	77.89	0.00e+00	2072.00
IUUC-Ogl-076926	Oryza glaberrima	80.36	0.00e+00	2128.00
IUUC-Ogu-078892	Oryza glumaepatula	79.84	0.00e+00	2112.00
IUUC-Oin-079148	Oryza indica	75.75	0.00e+00	1959.00
IUUC-Olo-081086	Oryza longistaminata	77.08	0.00e+00	2020.00
IUUC-Ome-081955	Oryza meridionalis	76.44	0.00e+00	2012.00
IUUC-Oni-083047	Oryza nivara	77.11	0.00e+00	2034.00
IUUC-Opu-083641	Oryza punctata	77.97	0.00e+00	2036.00
IUUC-Oru-084439	Oryza rufipogon	77.03	0.00e+00	2014.00
IUUC-Osa-085617	Oryza sativa	80.81	0.00e+00	831.00
IUUC-Pop-100082	Populus trichocarpa	46.78	0.00e+00	1135.00
IUUC-Ppe-101229	Prunus persica	47.56	0.00e+00	1159.00
IUUC-Sit-110332	Setaria italica	78.99	0.00e+00	2099.00
IUUC-Sly-111552	Solanum lycopersicum	45.65	0.00e+00	1111.00
IUUC-Sbi-114106	Sorghum bicolor	75.78	0.00e+00	2039.00
IUUC-Tca-121574	Theobroma cacao	46.45	0.00e+00	1155.00
IUUC-Tae-125470	Triticum aestivum	98.88	0.00e+00	2682.00
IUUC-Tur-126486	Triticum urartu	96.34	0.00e+00	2581.00
IUUC-Vvi-130904	Vitis vinifera	46.80	0.00e+00	1137.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence