iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068879

Ensembl Protein ID

EAA26929

UniProt Accession

Q7RWU7; Q7RWU7_NEUCR

Genbank Protein ID

EAA26929.3

Protein Name

Ubiquitin C-terminal hydrolase

Genbank Nucleotide ID

CM002238

Gene Name

NCU00480

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU00480	EAA26929	EAA26929

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-97	325.7	440	1256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeqqDaqEfla 97
           +Gl+NlgNtCYmNS+LQcL +++el++++l+ + k+++n +np +++g++++++ +l+ e++ +   ++v+pr+++ +++++a+ fsgy qqD+qEfl 
   Q: 440  VGLQNLGNTCYMNSALQCLRSVEELTKYFLThEAKKEINPDNPLSHNGDVAMAYMRLLDEIYkNPAPNSVAPRHFKGIVGRYAPAFSGYGQQDSQEFLG 538
           6*****************************989999**************************89999******************************** PP
   S: 98   flldqleeelkkeknkpkeeeeeedkselsde.............aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetk 183
           flld+l+e+l++ k+kp+ e+ +++    +d+              ++ +kk+ +s+i dlF g +ks++ c+ cd++s +++pf+ l+lp+p+++  +
   Q: 539  FLLDGLQEDLNRIKKKPYIEKPDST----DDMignpaaikemaekVWDITKKRDDSIIADLFTGLYKSTLHCPVCDKISITFDPFNNLTLPLPMSNVWS 633
           ************9999999998877....3335667889999999***************************************************998 PP
   S: 184  ke................................................................................................. 185
            +                                                                                                 
   Q: 634  RTvkyyplneppveivvevdktsafkaikefistrvgvpperlvggeefkgkffkqyddmmaineeiqpgdvaviheveapptnvnakkakkqvyrsll 732
           88************************************************************************************************* PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 733  ddaeeepaqptsnplaerllvpvlhrtmdpngagvryhrkvedippphyivltpqeacdeniirrkilqkvatlstwseftadeeaseatdpemvngas 831
           *************************************************************************************************** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 832  didsadskvvaksvegeedivdvtmgntgsakptaspapqtlpallkrfksqqpkwldpsvflnpalqnlfamsyfrelhggvptgwqsvndtskherl 930
           *************************************************************************************************** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 931  ssrapktdssdvemrspnaldgsddsgseeasseqvdsvtrmadessegsdapkgsdrfiaspprganavprgknkkmkagrtygkkakkrfekeqlrk 1029
           *************************************************************************************************** PP
   S: 186  ..............................................................................slqdcLesftkeeelegenky 206
                                                                                         sl+dcL++f kee l +++ +
   Q: 1030 raaaaqqpievpeqdyrvdseegplvrlgegivvdwyedafdtvfspanrtynkietlndpslgakkrqrelrkkhgiSLDDCLAEFEKEEILSEQDTW 1128
           *************************************************************************************************** PP
   S: 207  ycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ek 303
           yc++ck++++a+kk++l+k P++L++hLkRf  s+ +++r k++  v+fp+e Ldl++ ++++e+++  +++Y+Liav  H G+l++GHY+a++kn  +
   Q: 1129 YCPRCKEHRRASKKFDLWKTPDILVVHLKRF--SSVGWRRDKLDVLVDFPIEgLDLTERVIDKEDGK--QEIYDLIAVDDHWGGLGGGHYTAFAKNfVD 1223
           *******************************..8999*********************999988887..9**************************557 PP
   S: 304  gkWllfdDskVtevk.eeevleetgstaYvlfYkrr 338
           ++W++f+Ds+V++v+  ++v++     aY+lfY+rr
   Q: 1224 DQWYEFNDSSVSKVTdTSKVVS---PAAYLLFYRRR 1256
           77************73689999...********996 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MGGASEQTHR SGSPLKRRAS SMDPEFENAD SREDVEMLTV PDTQPQDQQP GQDVEEPQPV 60
EADAVGGTKV PIADMELPLK TEIPPIEQQI KTIETLLKAF NDRGAKEGDV AYLVSRQWLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAGACAAC GCCTAAAATT CCATTGGACG GAATTTCCAT CACCCGCTCT CTAAGCCTGC 60
CTATTGCTCC GGCTTCATTG TTGACAAGAA CCTCACTGCA GGGCAACCCC AAAGAGACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ncr:NCU00480

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	46.30	5.00e-50	191.00
IUUC-Aml-001597	Ailuropoda melanoleuca	44.98	2.00e-57	215.00
IUUC-Atr-002955	Amborella trichopoda	42.91	3.00e-49	188.00
IUUC-Apl-003249	Anas platyrhynchos	44.89	5.00e-60	224.00
IUUC-Aca-004261	Anolis carolinensis	44.89	1.00e-60	226.00
IUUC-Aly-006315	Arabidopsis lyrata	47.74	1.00e-47	183.00
IUUC-Ath-007677	Arabidopsis thaliana	37.73	1.00e-50	192.00
IUUC-Ago-007911	Ashbya gossypii	47.89	6.00e-77	281.00
IUUC-Acl-008284	Aspergillus clavatus	40.59	1.00e-162	566.00
IUUC-Afl-008507	Aspergillus flavus	40.82	2.00e-162	565.00
IUUC-Afu-008878	Aspergillus fumigatus	41.39	0.00e+00	824.00
IUUC-Ani-009479	Aspergillus nidulans	38.39	3.00e-148	518.00
IUUC-Ang-009562	Aspergillus niger	39.88	4.00e-152	531.00
IUUC-Aor-009949	Aspergillus oryzae	40.71	1.00e-160	558.00
IUUC-Ate-010323	Aspergillus terreus	38.21	3.00e-155	541.00
IUUC-Ame-011064	Astyanax mexicanus	47.14	3.00e-62	231.00
IUUC-Bgr-012277	Blumeria graminis	45.25	0.00e+00	1111.00
IUUC-Bta-012929	Bos taurus	44.74	8.00e-57	213.00
IUUC-Bci-013993	Botrytis cinerea	47.43	0.00e+00	1106.00
IUUC-Bdi-014013	Brachypodium distachyon	44.53	7.00e-54	204.00
IUUC-Bol-015158	Brassica oleracea	33.58	5.00e-52	197.00
IUUC-Bra-017029	Brassica rapa	45.22	6.00e-57	214.00
IUUC-Cel-018203	Caenorhabditis elegans	49.32	1.00e-54	206.00
IUUC-Cja-019222	Callithrix jacchus	45.83	3.00e-61	228.00
IUUC-Cfa-020599	Canis familiaris	44.74	2.00e-56	212.00
IUUC-Cpo-022144	Cavia porcellus	43.80	4.00e-55	207.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	50.00	4.00e-49	186.00
IUUC-Csa-023770	Chlorocebus sabaeus	44.74	7.00e-57	214.00
IUUC-Cho-024595	Choloepus hoffmanni	43.84	1.00e-56	213.00
IUUC-Cin-025292	Ciona intestinalis	40.88	7.00e-58	217.00
IUUC-Csv-026109	Ciona savignyi	39.26	9.00e-56	210.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	47.68	0.00e+00	1184.00
IUUC-Cne-026852	Cryptococcus neoformans	38.16	5.00e-68	251.00
IUUC-Cme-027338	Cyanidioschyzon merolae	42.29	1.00e-52	199.00
IUUC-Dre-027869	Danio rerio	44.67	2.00e-63	235.00
IUUC-Dno-029316	Dasypus novemcinctus	44.12	4.00e-56	211.00
IUUC-Dor-031038	Dipodomys ordii	55.25	1.00e-53	203.00
IUUC-Dse-031432	Dothistroma septosporum	34.56	4.00e-111	394.00
IUUC-Dme-032094	Drosophila melanogaster	37.50	9.00e-42	164.00
IUUC-Ete-032970	Echinops telfairi	48.03	2.00e-52	199.00
IUUC-Eca-034012	Equus caballus	44.66	1.00e-55	209.00
IUUC-Eeu-034488	Erinaceus europaeus	46.59	1.00e-61	229.00
IUUC-Fca-035373	Felis catus	45.11	7.00e-57	214.00
IUUC-Fal-037634	Ficedula albicollis	46.07	1.00e-56	213.00
IUUC-Fox-037986	Fusarium oxysporum	49.89	0.00e+00	1116.00
IUUC-Fso-038291	Fusarium solani	47.06	0.00e+00	1156.00
IUUC-Gmo-038866	Gadus morhua	45.45	6.00e-64	237.00
IUUC-Ggr-039740	Gaeumannomyces graminis	50.28	0.00e+00	1355.00
IUUC-Gga-040729	Gallus gallus	47.14	6.00e-63	234.00
IUUC-Gac-041679	Gasterosteus aculeatus	44.57	2.00e-60	226.00
IUUC-Gma-043077	Glycine max	39.02	1.00e-56	213.00
IUUC-Ggo-045337	Gorilla gorilla	45.11	4.00e-57	214.00
IUUC-Hsa-045669	Homo sapiens	45.11	5.00e-57	214.00
IUUC-Hvu-047108	Hordeum vulgare	45.83	3.00e-49	188.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	40.00	4.00e-62	231.00
IUUC-Kpa-049332	Komagataella pastoris	38.74	8.00e-78	283.00
IUUC-Lch-050533	Latimeria chalumnae	45.96	8.00e-63	233.00
IUUC-Lpe-051047	Leersia perrieri	42.50	8.00e-55	207.00
IUUC-Loc-052105	Lepisosteus oculatus	44.71	5.00e-56	211.00
IUUC-Lma-052981	Leptosphaeria maculans	36.80	0.00e+00	719.00
IUUC-Laf-053803	Loxodonta africana	45.11	6.00e-57	214.00
IUUC-Mcc-055556	Macaca mulatta	44.74	5.00e-57	214.00
IUUC-Meu-056742	Macropus eugenii	44.32	5.00e-57	214.00
IUUC-Mor-056985	Magnaporthe oryzae	48.32	0.00e+00	1151.00
IUUC-Mpo-057486	Magnaporthe poae	49.36	0.00e+00	1288.00
IUUC-Mtr-058138	Medicago truncatula	39.18	2.00e-57	215.00
IUUC-Mla-058848	Melampsora laricipopulina	43.20	2.00e-62	233.00
IUUC-Mga-059300	Meleagris gallopavo	45.71	1.00e-61	229.00
IUUC-Mvi-060324	Microbotryum violaceum	45.16	1.00e-64	240.00
IUUC-Mmr-061105	Microcebus murinus	46.59	7.00e-62	230.00
IUUC-Mdo-061848	Monodelphis domestica	43.94	2.00e-56	212.00
IUUC-Mmu-063960	Mus musculus	44.78	4.00e-57	214.00
IUUC-Mac-064956	Musa acuminata	35.58	2.00e-55	209.00
IUUC-Mpu-066920	Mustela putorius furo	45.49	6.00e-57	214.00
IUUC-Mlu-068088	Myotis lucifugus	45.86	1.00e-57	216.00
IUUC-Nfi-068330	Neosartorya fischeri	40.51	1.00e-167	582.00
IUUC-Nle-070010	Nomascus leucogenys	45.11	3.00e-57	215.00
IUUC-Opr-070740	Ochotona princeps	44.74	1.00e-56	213.00
IUUC-Ont-072573	Oreochromis niloticus	45.71	3.00e-64	238.00
IUUC-Oan-073363	Ornithorhynchus anatinus	43.49	4.00e-56	211.00
IUUC-Ocu-074573	Oryctolagus cuniculus	45.83	2.00e-60	225.00
IUUC-Oba-075427	Oryza barthii	54.74	2.00e-53	202.00
IUUC-Obr-076416	Oryza brachyantha	41.26	3.00e-50	191.00
IUUC-Ogl-077583	Oryza glaberrima	47.52	3.00e-50	192.00
IUUC-Ogu-078422	Oryza glumaepatula	54.74	2.00e-53	202.00
IUUC-Oin-079453	Oryza indica	44.36	2.00e-53	202.00
IUUC-Olo-080315	Oryza longistaminata	43.97	4.00e-53	201.00
IUUC-Ome-081271	Oryza meridionalis	44.36	1.00e-53	203.00
IUUC-Oni-082834	Oryza nivara	54.74	2.00e-53	202.00
IUUC-Opu-083691	Oryza punctata	40.21	7.00e-50	190.00
IUUC-Oru-084820	Oryza rufipogon	54.74	2.00e-53	202.00
IUUC-Osa-086139	Oryza sativa	44.36	2.00e-53	202.00
IUUC-Ola-086553	Oryzias latipes	44.64	1.00e-62	233.00
IUUC-Olu-087717	Ostreococcus lucimarinus	37.00	6.00e-48	184.00
IUUC-Oga-088562	Otolemur garnettii	43.28	4.00e-55	208.00
IUUC-Oar-090439	Ovis aries	44.40	6.00e-57	214.00
IUUC-Ptr-090801	Pan troglodytes	45.11	4.00e-57	214.00
IUUC-Pan-092717	Papio anubis	44.74	5.00e-57	214.00
IUUC-Psi-093849	Pelodiscus sinensis	45.62	5.00e-61	228.00
IUUC-Pma-094533	Petromyzon marinus	47.17	8.00e-61	227.00
IUUC-Pno-094890	Phaeosphaeria nodorum	35.13	6.00e-138	484.00
IUUC-Ppa-095825	Physcomitrella patens	30.95	1.00e-19	90.50
IUUC-Pfo-097060	Poecilia formosa	46.43	3.00e-66	244.00
IUUC-Pab-098522	Pongo abelii	44.74	9.00e-57	213.00
IUUC-Pop-099313	Populus trichocarpa	43.80	1.00e-55	209.00
IUUC-Pca-100161	Procavia capensis	43.61	2.00e-54	206.00
IUUC-Ppe-101587	Prunus persica	53.06	6.00e-55	207.00
IUUC-Pva-103244	Pteropus vampyrus	35.29	1.00e-56	213.00
IUUC-Pgr-103546	Puccinia graminis	39.09	1.00e-59	223.00
IUUC-Ptt-103847	Puccinia triticina	38.78	3.00e-59	222.00
IUUC-Pte-104102	Pyrenophora teres	35.14	2.00e-140	492.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	38.36	4.00e-113	402.00
IUUC-Rno-106081	Rattus norvegicus	31.90	2.00e-65	242.00
IUUC-Sce-106170	Saccharomyces cerevisiae	42.41	2.00e-72	266.00
IUUC-Sha-106937	Sarcophilus harrisii	44.32	5.00e-57	214.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	30.51	2.00e-79	288.00
IUUC-Spo-108291	Schizosaccharomyces pombe	32.30	9.00e-96	343.00
IUUC-Smo-109356	Selaginella moellendorffii	55.79	4.00e-55	207.00
IUUC-Sit-109948	Setaria italica	55.73	1.00e-54	206.00
IUUC-Sly-111746	Solanum lycopersicum	36.41	8.00e-56	210.00
IUUC-Stu-112671	Solanum tuberosum	36.08	8.00e-56	210.00
IUUC-Sar-113542	Sorex araneus	46.21	6.00e-61	227.00
IUUC-Sbi-114874	Sorghum bicolor	55.73	1.00e-54	206.00
IUUC-Sre-115130	Sporisorium reilianum	37.53	4.00e-71	261.00
IUUC-Ssc-115637	Sus scrofa	45.15	5.00e-57	214.00
IUUC-Tgu-117267	Taeniopygia guttata	46.79	8.00e-58	217.00
IUUC-Tru-118298	Takifugu rubripes	30.65	5.00e-66	244.00
IUUC-Tsy-119414	Tarsius syrichta	44.53	4.00e-58	217.00
IUUC-Tni-120799	Tetraodon nigroviridis	31.73	8.00e-68	250.00
IUUC-Tca-121001	Theobroma cacao	38.38	2.00e-58	218.00
IUUC-Tre-121888	Trichoderma reesei	48.30	0.00e+00	1123.00
IUUC-Tvi-122422	Trichoderma virens	46.83	0.00e+00	1118.00
IUUC-Tae-124994	Triticum aestivum	43.73	7.00e-56	210.00
IUUC-Tur-126392	Triticum urartu	43.11	2.00e-45	175.00
IUUC-Tme-127062	Tuber melanosporum	48.44	4.00e-99	354.00
IUUC-Tbe-127672	Tupaia belangeri	45.16	4.00e-62	231.00
IUUC-Ttr-128778	Tursiops truncatus	43.75	6.00e-56	211.00
IUUC-Uma-129498	Ustilago maydis	35.28	3.00e-63	235.00
IUUC-Vda-129781	Verticillium dahliae	49.79	0.00e+00	1168.00
IUUC-Vpa-130571	Vicugna pacos	45.11	1.00e-56	213.00
IUUC-Vvi-131010	Vitis vinifera	45.04	1.00e-56	213.00
IUUC-Xtr-132305	Xenopus tropicalis	44.77	1.00e-64	239.00
IUUC-Xma-133550	Xiphophorus maculatus	45.09	1.00e-62	233.00
IUUC-Yli-134392	Yarrowia lipolytica	39.09	1.00e-74	273.00
IUUC-Zma-135361	Zea mays	41.52	2.00e-54	205.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence