• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046630
UUCD1 version UUC-HoS-00664
Ensembl Protein ID ENSP00000377086.3
UniProt Accession Q1L5Z9; B9A006; Q6ZSR4; LONF2_HUMAN
Genbank Protein ID AAY84832.1; BAC86883.1; AAI01665.1; AAI01663.1
Protein Name LON peptidase N-terminal domain and RING finger protein 2; Neuroblastoma apoptosis-related protease; RING finger protein 192
Genbank Nucleotide ID DQ020495; AK127206; AC104782; BC101662
Gene Name LONRF2; RNF192
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000170500.12 ENST00000393437.7 ENSP00000377086.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbAREsitecircRNADbCircNet
miRTarBaseTRANSFACTargetScanRepTar
SomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbGWAS Central
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 8.30e-08 33.9 446 492
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           +f C++ + l  +Pv++p+G+t+  +++e++l++  + cP+++ +l+e
   Q: 446  DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPH-CPLCKDKLSE 492
           79***********************************.******9976 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MSPEPVPPPP PPQCPGCDRA EPIAQRLEEG DEAFRAGDYE MAAELFRSML AGLAQPDRGL 60
CLRLGDALAR AGRLPEALGA FRGAARLGAL RPEELEELAG GLVRAVGLRD RPLSAENPGG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046630|E3,U-box|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCTCCCCAGT CATTTAGGAC AATTTCCTAA GTCGAAGCTA GAGATGCGTG ATGCGTTTGG 60
TGACTTTTCC TGGGTTCTTG CTTAAGCGGA GCCACAGGTT GTGGGGGCGG CCAGGCCTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046630|E3,U-box|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02190--LON_substr_bdg
PF13445--zf-RING_UBOX
SMART

SM00464--LON
SM00184--RING
SM00028--TPR
Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
KEGG hsa:164832
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001867 Ailuropoda melanoleuca 87.31 0.00e+00 1026.00
IUUC-Apl-003355 Anas platyrhynchos 63.28 0.00e+00 676.00
IUUC-Aca-004822 Anolis carolinensis 56.44 0.00e+00 743.00
IUUC-Acl-008224 Aspergillus clavatus 31.96 1.00e-40 161.00
IUUC-Afu-008802 Aspergillus fumigatus 29.91 1.00e-37 151.00
IUUC-Ani-009473 Aspergillus nidulans 31.90 9.00e-42 165.00
IUUC-Ate-010489 Aspergillus terreus 33.85 1.00e-39 158.00
IUUC-Ame-010750 Astyanax mexicanus 49.35 0.00e+00 657.00
IUUC-Cja-019041 Callithrix jacchus 88.39 0.00e+00 1202.00
IUUC-Cfa-020025 Canis familiaris 86.33 0.00e+00 1030.00
IUUC-Cre-022730 Chlamydomonas reinhardtii 55.81 9.00e-09 53.90
IUUC-Csa-023324 Chlorocebus sabaeus 98.63 0.00e+00 1011.00
IUUC-Cin-025668 Ciona intestinalis 33.49 3.00e-94 339.00
IUUC-Cne-026875 Cryptococcus neoformans 28.57 4.00e-08 53.50
IUUC-Dre-028400 Danio rerio 51.59 3.00e-145 508.00
IUUC-Eeu-034779 Erinaceus europaeus 66.54 0.00e+00 639.00
IUUC-Fca-036276 Felis catus 87.36 0.00e+00 1030.00
IUUC-Fal-036669 Ficedula albicollis 61.12 0.00e+00 686.00
IUUC-Fso-038334 Fusarium solani 29.77 5.00e-41 162.00
IUUC-Gga-041253 Gallus gallus 59.03 0.00e+00 735.00
IUUC-Gma-042919 Glycine max 34.21 2.00e-38 153.00
IUUC-Ggo-045501 Gorilla gorilla 99.19 0.00e+00 1342.00
IUUC-Itr-048224 Ictidomys tridecemlineatus 81.42 0.00e+00 818.00
IUUC-Lch-049788 Latimeria chalumnae 49.73 0.00e+00 647.00
IUUC-Loc-051922 Lepisosteus oculatus 50.33 0.00e+00 639.00
IUUC-Laf-054421 Loxodonta africana 57.68 0.00e+00 770.00
IUUC-Mcc-054828 Macaca mulatta 98.04 0.00e+00 1006.00
IUUC-Meu-055901 Macropus eugenii 52.74 3.00e-174 605.00
IUUC-Mtr-058075 Medicago truncatula 36.96 3.00e-43 169.00
IUUC-Mga-059760 Meleagris gallopavo 61.63 0.00e+00 676.00
IUUC-Mmr-061350 Microcebus murinus 80.03 0.00e+00 936.00
IUUC-Mdo-062203 Monodelphis domestica 58.63 0.00e+00 792.00
IUUC-Mmu-064118 Mus musculus 78.81 0.00e+00 787.00
IUUC-Mpu-065764 Mustela putorius furo 84.84 0.00e+00 1112.00
IUUC-Nfi-068337 Neosartorya fischeri 31.65 5.00e-38 152.00
IUUC-Nle-069616 Nomascus leucogenys 98.92 0.00e+00 1345.00
IUUC-Ont-072142 Oreochromis niloticus 48.47 0.00e+00 659.00
IUUC-Oga-088972 Otolemur garnettii 87.18 0.00e+00 1177.00
IUUC-Ptr-090992 Pan troglodytes 99.48 0.00e+00 1120.00
IUUC-Pan-092180 Papio anubis 96.63 0.00e+00 1308.00
IUUC-Psi-093423 Pelodiscus sinensis 62.89 0.00e+00 669.00
IUUC-Pfo-096363 Poecilia formosa 50.00 0.00e+00 644.00
IUUC-Pab-097974 Pongo abelii 98.11 0.00e+00 1330.00
IUUC-Pop-100044 Populus trichocarpa 36.94 4.00e-43 169.00
IUUC-Pva-102269 Pteropus vampyrus 79.09 0.00e+00 1076.00
IUUC-Pgr-103289 Puccinia graminis 26.78 1.00e-26 114.00
IUUC-Rno-105905 Rattus norvegicus 80.04 0.00e+00 818.00
IUUC-Ssc-116224 Sus scrofa 72.09 7.00e-180 624.00
IUUC-Tgu-117000 Taeniopygia guttata 61.13 0.00e+00 706.00
IUUC-Tru-118016 Takifugu rubripes 48.38 1.00e-179 623.00
IUUC-Tni-119913 Tetraodon nigroviridis 47.79 1.00e-163 570.00
IUUC-Ttr-128666 Tursiops truncatus 78.89 0.00e+00 1065.00
IUUC-Uma-129541 Ustilago maydis 33.98 2.00e-33 138.00
IUUC-Vpa-130334 Vicugna pacos 65.23 3.00e-173 601.00
IUUC-Vvi-130910 Vitis vinifera 33.64 3.00e-39 156.00
IUUC-Xtr-132065 Xenopus tropicalis 50.33 0.00e+00 684.00
IUUC-Xma-134324 Xiphophorus maculatus 50.00 0.00e+00 651.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved