iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000997

Ensembl Protein ID

EMT31968

UniProt Accession

M8CCU3; M8CCU3_AEGTA

Genbank Protein ID

EMT31968.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

KD502612

Gene Name

F775_05933

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_05933	EMT31968	EMT31968

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-72	245.9	207	660

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEflafl 99
           +Gl NlgNtC++N+vLQ+L+++ ++r+ +l           p+ p+g++++sl+klf e    ++  +a sp++l+++++++ ++f+gy+ qD++E+l+++
   Q: 207  KGLPNLGNTCFFNAVLQSLLALDKFRSKMLG----------PDVPTGAIAMSLKKLFVETSasNDAGGALSPKSLFSSICSKYPQFKGYQMQDSHELLRCF 297
           59*****************************..........345789**********99987788888********************************* PP
   S: 100  ldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke............... 185
           ld+l +e ++               +++  ++ +     +++++ +F+gql+s++   ec + s+++++fldlslpvp+++  + +               
   Q: 298  LDGLGTEETE---------------ARNAAEDASSAAGVPTIVDSIFGGQLSSTVSSTECTHGSVKHDQFLDLSLPVPSRKPPARSvssppakrtkqsird 383
           ******9922...............3444467789999******************************************98777799************* PP
   S: 186  ..................................................................................................... 185
                                                                                                                
   Q: 384  rnknrrygkvatrvspaiaesskeqvqtvaegndsqipgselgqvvsekehepsecsescasvpnqelkaasnveadiswldyladadetkseildsacst 484
           ***************************************************************************************************** PP
   S: 186  ..................................................................................................... 185
                                                                                                                
   Q: 485  gagqiwnsndaaihgsfhsgddalpkeqalisehsgenivddatclqtvillpykefdttaeeiyetaessqnpivfgphpadylaaenhaqplyggdgeq 585
           ***************************************************************************************************** PP
   S: 186  ..................................................slqdcLesftkeeelegenkyycekck 212
                                                             s++ cL+ +t++e l +   ++ce+c 
   Q: 586  ddcfgigdmfgepevtsdakketgttgdidvmawssnsaddevddsnapvSVEGCLSLYTEPELLSE--SWHCENCS 660
           *****************************************************************85..8******7 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MGKKVKAKPK KAQQREPLAD AGSGDEASQD VEEAAASAGD WEQCGHYSRD GRHLDKVLRE 60
IVSAKHLASC EHCREEAPRK KGGGGGKEKG GKQQKKKGAA AKTQAKAEKN DDLWVCLDCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAAAGA AGGTGAAGGC CAAGCCGAAG AAGGCGCAGC AGCGGGAGCC GCTGGCCGAC 60
GCTGGATCCG GCGACGAGGC CTCGCAGGAC GTCGAGGAAG CGGCTGCGTC GGCCGGCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ats:F775_05933

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001931	Ailuropoda melanoleuca	31.07	1.00e-32	134.00
IUUC-Atr-003015	Amborella trichopoda	30.91	6.00e-65	242.00
IUUC-Apl-004145	Anas platyrhynchos	30.40	3.00e-29	123.00
IUUC-Aca-004314	Anolis carolinensis	30.06	1.00e-26	114.00
IUUC-Aly-005494	Arabidopsis lyrata	33.96	7.00e-46	178.00
IUUC-Ath-007211	Arabidopsis thaliana	35.97	5.00e-48	185.00
IUUC-Ame-011659	Astyanax mexicanus	32.49	1.00e-24	107.00
IUUC-Bta-013362	Bos taurus	30.64	4.00e-30	125.00
IUUC-Bdi-014465	Brachypodium distachyon	74.55	0.00e+00	1422.00
IUUC-Bol-015191	Brassica oleracea	35.42	6.00e-54	205.00
IUUC-Bra-016751	Brassica rapa	39.51	4.00e-46	179.00
IUUC-Cja-019177	Callithrix jacchus	36.28	2.00e-31	130.00
IUUC-Cfa-020051	Canis familiaris	32.11	2.00e-32	133.00
IUUC-Cpo-021886	Cavia porcellus	31.02	7.00e-33	135.00
IUUC-Csa-024103	Chlorocebus sabaeus	36.28	2.00e-31	130.00
IUUC-Cho-024315	Choloepus hoffmanni	41.96	4.00e-20	92.40
IUUC-Cin-025775	Ciona intestinalis	33.79	6.00e-17	79.00
IUUC-Csv-026075	Ciona savignyi	31.02	3.00e-17	82.80
IUUC-Cme-027348	Cyanidioschyzon merolae	36.76	2.00e-18	87.00
IUUC-Dre-028388	Danio rerio	35.53	1.00e-25	111.00
IUUC-Dno-029409	Dasypus novemcinctus	29.38	5.00e-30	125.00
IUUC-Dor-030443	Dipodomys ordii	36.91	2.00e-23	103.00
IUUC-Dme-031870	Drosophila melanogaster	28.64	5.00e-14	73.20
IUUC-Ete-032807	Echinops telfairi	36.67	8.00e-24	105.00
IUUC-Eca-033479	Equus caballus	30.64	4.00e-32	132.00
IUUC-Eeu-034835	Erinaceus europaeus	32.97	2.00e-23	103.00
IUUC-Fca-036320	Felis catus	31.59	1.00e-33	137.00
IUUC-Fal-037029	Ficedula albicollis	30.56	2.00e-31	130.00
IUUC-Gmo-039480	Gadus morhua	34.30	4.00e-25	108.00
IUUC-Gga-040527	Gallus gallus	29.15	2.00e-27	117.00
IUUC-Gac-042343	Gasterosteus aculeatus	33.82	1.00e-24	107.00
IUUC-Gma-044402	Glycine max	32.04	1.00e-76	281.00
IUUC-Ggo-045598	Gorilla gorilla	35.81	1.00e-30	128.00
IUUC-Hsa-046598	Homo sapiens	35.81	9.00e-31	128.00
IUUC-Hvu-047146	Hordeum vulgare	93.96	0.00e+00	1790.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	30.06	4.00e-33	135.00
IUUC-Lch-050536	Latimeria chalumnae	29.39	4.00e-28	119.00
IUUC-Lpe-050703	Leersia perrieri	66.70	0.00e+00	1219.00
IUUC-Loc-051814	Lepisosteus oculatus	28.49	9.00e-27	114.00
IUUC-Laf-053732	Loxodonta africana	30.66	1.00e-33	137.00
IUUC-Mcc-054661	Macaca mulatta	36.28	2.00e-31	130.00
IUUC-Meu-055967	Macropus eugenii	28.61	1.00e-21	97.80
IUUC-Mtr-057945	Medicago truncatula	40.50	5.00e-55	209.00
IUUC-Mla-059026	Melampsora laricipopulina	37.12	7.00e-19	88.20
IUUC-Mga-059551	Meleagris gallopavo	29.61	2.00e-31	130.00
IUUC-Mvi-060391	Microbotryum violaceum	35.06	5.00e-19	89.40
IUUC-Mmr-061747	Microcebus murinus	29.77	1.00e-32	134.00
IUUC-Mdo-062220	Monodelphis domestica	29.39	2.00e-27	116.00
IUUC-Mmu-063582	Mus musculus	29.36	9.00e-30	124.00
IUUC-Mac-064941	Musa acuminata	47.87	4.00e-82	298.00
IUUC-Mpu-066339	Mustela putorius furo	31.36	1.00e-32	134.00
IUUC-Mlu-067511	Myotis lucifugus	36.28	2.00e-31	130.00
IUUC-Nle-069252	Nomascus leucogenys	36.28	1.00e-31	130.00
IUUC-Opr-070969	Ochotona princeps	36.28	4.00e-30	125.00
IUUC-Ont-071786	Oreochromis niloticus	33.00	9.00e-25	108.00
IUUC-Oan-073656	Ornithorhynchus anatinus	29.45	6.00e-27	115.00
IUUC-Ocu-074704	Oryctolagus cuniculus	29.68	4.00e-33	136.00
IUUC-Oba-075094	Oryza barthii	70.63	0.00e+00	1289.00
IUUC-Obr-076743	Oryza brachyantha	68.39	0.00e+00	1197.00
IUUC-Ogl-077739	Oryza glaberrima	67.97	0.00e+00	1028.00
IUUC-Ogu-078851	Oryza glumaepatula	70.63	0.00e+00	1290.00
IUUC-Oin-079402	Oryza indica	70.63	0.00e+00	1289.00
IUUC-Olo-080431	Oryza longistaminata	70.85	0.00e+00	1262.00
IUUC-Ome-081580	Oryza meridionalis	70.03	0.00e+00	1278.00
IUUC-Oni-082644	Oryza nivara	70.63	0.00e+00	1289.00
IUUC-Opu-083452	Oryza punctata	70.79	0.00e+00	1280.00
IUUC-Oru-084546	Oryza rufipogon	70.73	0.00e+00	1290.00
IUUC-Osa-085858	Oryza sativa	70.43	0.00e+00	1285.00
IUUC-Ola-086795	Oryzias latipes	33.02	1.00e-24	107.00
IUUC-Oga-088713	Otolemur garnettii	29.97	1.00e-32	134.00
IUUC-Oar-089971	Ovis aries	30.55	2.00e-30	126.00
IUUC-Ptr-091670	Pan troglodytes	35.81	6.00e-31	129.00
IUUC-Pan-092293	Papio anubis	36.28	2.00e-31	130.00
IUUC-Psi-093101	Pelodiscus sinensis	35.50	1.00e-26	114.00
IUUC-Ppa-095584	Physcomitrella patens	46.54	3.00e-37	150.00
IUUC-Pfo-097202	Poecilia formosa	36.36	3.00e-27	116.00
IUUC-Pab-098773	Pongo abelii	35.81	1.00e-30	127.00
IUUC-Pop-099588	Populus trichocarpa	32.52	1.00e-63	237.00
IUUC-Pca-101069	Procavia capensis	33.33	6.00e-24	105.00
IUUC-Ppe-101794	Prunus persica	33.33	2.00e-65	243.00
IUUC-Pva-103092	Pteropus vampyrus	35.14	1.00e-24	107.00
IUUC-Rno-105237	Rattus norvegicus	34.42	1.00e-27	118.00
IUUC-Sha-106889	Sarcophilus harrisii	30.67	6.00e-28	118.00
IUUC-Sja-107712	Schizosaccharomyces japonicus	32.24	2.00e-18	87.00
IUUC-Spo-108149	Schizosaccharomyces pombe	36.42	4.00e-23	103.00
IUUC-Sit-110283	Setaria italica	66.29	0.00e+00	1259.00
IUUC-Sly-111487	Solanum lycopersicum	31.95	1.00e-67	251.00
IUUC-Stu-112499	Solanum tuberosum	30.60	5.00e-71	262.00
IUUC-Sar-113530	Sorex araneus	31.91	3.00e-32	132.00
IUUC-Sbi-113785	Sorghum bicolor	65.72	0.00e+00	1172.00
IUUC-Ssc-116091	Sus scrofa	36.54	1.00e-30	127.00
IUUC-Tgu-117478	Taeniopygia guttata	30.79	2.00e-30	126.00
IUUC-Tru-118640	Takifugu rubripes	35.29	7.00e-25	108.00
IUUC-Tsy-118869	Tarsius syrichta	35.35	3.00e-23	102.00
IUUC-Tni-120015	Tetraodon nigroviridis	29.23	2.00e-26	113.00
IUUC-Tca-121701	Theobroma cacao	30.70	5.00e-69	255.00
IUUC-Tae-125305	Triticum aestivum	99.22	0.00e+00	1838.00
IUUC-Tur-126788	Triticum urartu	96.42	0.00e+00	1593.00
IUUC-Tbe-128041	Tupaia belangeri	35.15	2.00e-23	103.00
IUUC-Ttr-128271	Tursiops truncatus	30.84	4.00e-33	135.00
IUUC-Vpa-130674	Vicugna pacos	31.12	2.00e-32	134.00
IUUC-Xtr-131869	Xenopus tropicalis	29.88	2.00e-28	120.00
IUUC-Xma-134195	Xiphophorus maculatus	36.36	6.00e-27	115.00
IUUC-Yli-134571	Yarrowia lipolytica	34.85	1.00e-12	67.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence