iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015853

Ensembl Protein ID

Bo8g004280.1

UniProt Accession

A0A0D3DIX2; A0A0D3DIX2_BRAOL

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo8g004280	Bo8g004280.1	Bo8g004280.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.40e-82	276.9	231	934

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEfl 96
           Gl NlgNtC++NS++Q L+++ +lr+ +l+++ +        +  g+l++sl+klf+e     + k++++pr ++ +++ +a++f+gy+q+D++E+l
   Q: 231  GLVNLGNTCFFNSIMQNLLSLDQLRDHFLKEDAS--------GIGGTLACSLKKLFAETKpeAGLKSVINPRVFFGSFCVKAPQFRGYDQHDSHELL 319
           9*****************************4444........45689************99999********************************* PP
   S: 97   aflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke........ 185
           ++lld+l++e +         +       +++   +++++k+++li+ +F+g+++s + c ec+++s+ +epfldlslpvp k++  k+        
   Q: 320  RCLLDSLSTEESA--------L-------RKKRGVSDNDEKSTTLIESVFGGETSSIVSCMECGHSSKVYEPFLDLSLPVPFKKTPPKKqptvslak 401
           **********922........1.......2222445678999***************************************9998766699****** PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 402  kaklppkrvakhvskvskvskvlpskalldpkspgkgavvpadpdassssfapvdngtvsdnkqgsesvtqsdsvfdnfwldvigpdpfgdetnvdt 498
           ************************************************************************************************* PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 499  edsvsdkittteanqilpgpdnssntstlegnterlmqdndeiikaetflddkdeqamqhdegtatsgvsteinqasfigcdpglgessssvnpwde 595
           ************************************************************************************************* PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 596  eelplmvadsqvlympykenisydddkpaveegegeassssfvagdheppqdndfvglgglfdepevtegpvvfgppcnpeassggagfmafssesd 692
           ************************************************************************************************* PP
   S: 186  ...........slqdcLesftkeeelegenkyycekck........................................................... 212
                      s++ cL++ftk+e l ++n+++ce+c                                                            
   Q: 693  peeiddsdspvSVERCLAHFTKPEILSDDNAWNCENCSknlklqrlkekrkskkdesrssntsngwvsenedvsamkqdpsdgsssvkddgkeamss 789
           **************************************99999999999999999999999999999999999999999999999999999999999 PP
   S: 213  .....................kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG 288
                                 k++a+k++ ++k P+vL++hLkRfs + + ++ +k+n +v f++ +dl++++ s++++++ +  Y+L + v HsG
   Q: 790  nsandsvseeeseedsekvttVKRDATKRVLVNKTPPVLTIHLKRFSQDLR-GRLSKLNGHVAFKEVIDLRQYMDSRCSGED-SPVYRLAGLVEHSG 884
           9999999988888888888887777*********************98887.8889**********************9985.9************* PP
   S: 289  slssGHYvayvknekgk....WllfdDskVtevkeeevleetgstaYvlfYkr 337
           ++++GHYvayv+  +++    W++++D +V++v+ ++v     s+aY+lfY+r
   Q: 885  TMRGGHYVAYVRGGQKGkesvWYNISDAHVRQVSLDKVMH---SEAYILFYER 934
           ************955556889*******************...********98 PP

Organism

Brassica oleracea

Protein Sequence
(Fasta)

MGKKAKKKSR TPTKENLSKK VSEQPSETGE ITAGGSVQAV KEKQACVHFD KGLNLDKLLE 60
KIKSSRQIKC QECKEGVHGK RGAKEKVNKG KHAFSSSAAD PKADKKAIWV CLECGAFVCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAGA AAGCGAAGAA GAAGTCCCGA ACCCCAACTA AGGAGAATCT CTCCAAGAAG 60
GTCTCTGAGC AGCCTAGTGA GACCGGGGAA ATAACTGCGG GAGGTTCAGT TCAAGCAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003015	Amborella trichopoda	35.37	9.00e-64	238.00
IUUC-Aly-005494	Arabidopsis lyrata	73.37	0.00e+00	1208.00
IUUC-Ath-007211	Arabidopsis thaliana	74.97	0.00e+00	1254.00
IUUC-Ame-011659	Astyanax mexicanus	32.64	5.00e-28	119.00
IUUC-Bdi-014624	Brachypodium distachyon	35.26	2.00e-49	190.00
IUUC-Dor-030443	Dipodomys ordii	40.00	2.00e-25	110.00
IUUC-Dme-031870	Drosophila melanogaster	33.98	2.00e-19	91.30
IUUC-Ete-032807	Echinops telfairi	40.00	1.00e-25	112.00
IUUC-Mtr-057945	Medicago truncatula	51.92	7.00e-100	358.00
IUUC-Pfo-097202	Poecilia formosa	29.44	2.00e-33	137.00
IUUC-Pop-099136	Populus trichocarpa	46.17	0.00e+00	700.00
IUUC-Ppe-101794	Prunus persica	42.16	8.00e-117	414.00
IUUC-Pva-103092	Pteropus vampyrus	40.00	7.00e-26	112.00
IUUC-Smo-108942	Selaginella moellendorffii	60.48	2.00e-42	166.00
IUUC-Sly-111491	Solanum lycopersicum	40.93	8.00e-173	600.00
IUUC-Stu-112820	Solanum tuberosum	41.39	5.00e-178	618.00
IUUC-Tni-120015	Tetraodon nigroviridis	26.96	8.00e-32	132.00
IUUC-Tca-121701	Theobroma cacao	48.67	1.00e-162	566.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence