iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
CPLM	dbPAF	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/GAT	GAT	17494868

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/GAT	9.50e-45	150.2	196	320

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/GAT

   S: 1    deeksklLerLlkskkPeDLreAnkLikelvkededkaekikklis.eleevksnvkllnemlselspegeepednellqelyetckaarpkllklieeeed 101
           +++++++Le+L++++kPeDLreAnkL+k++++++ed+a+++k++is el+++k++++llneml+  sp+++++ dne++qel++++k a+pk++k+ieee++
   Q: 196  EIAQAAKLEELIRRGKPEDLREANKLMKIMAGFKEDNAVQAKQAISsELNKLKRKADLLNEMLE--SPDSQNW-DNETTQELHSALKVAQPKFQKIIEEEQE 294
           579*************************************************************..*******.**************************** PP
   S: 102  ndellaellkanDelnqvlnkykqlk 127
           +d+l+++llk+nD++nq+l+k++ lk
   Q: 295  DDALVQDLLKFNDTVNQLLEKFNLLK 320
           **********************9876 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

May play a role in the regulation of membrane traffic through the trans-Golgi network.

Protein Sequence
(Fasta)

MSHPHSHSIY LSELPVRKPQ ALGNPLLRKI QRACRMSLAE PDLALNLDIA DYINEKQGAA 60
PRDAAIALAK LINNRESHVA IFALSLLDVL VKNCGYPFHL QISRKEFLNE LVKRFPGHPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCATC CGCACTCACA TAGCATATAT TTGTCTGAGT TGCCCGTCAG GAAACCTCAA 60
GCCTTGGGCA ATCCTCTTTT GAGGAAGATT CAAAGAGCTT GCAGAATGTC ACTTGCTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0333--Golgi apparatus
KW-1017--Isopeptide bond
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0832--Ubl conjugation

Interpro

IPR008152--Clathrin_a/b/g-adaptin_app_Ig
IPR008153--Clathrin_g-adaptin_app
IPR013041--Coatomer/clathrin_app_Ig-like
IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR002014--VHS_dom

PROSITE

PS50180--GAE
PS50909--GAT
PS50179--VHS

Pfam

PF02883--Alpha_adaptinC2
PF03127--GAT
PF00790--VHS

SMART

SM00809--Alpha_adaptinC2
SM00288--VHS

Gene Ontology

GO:0030131--C:clathrin adaptor complex
GO:0005829--C:cytosol
GO:0005802--C:trans-Golgi network
GO:0042802--F:identical protein binding
GO:0070273--F:phosphatidylinositol-4-phosphate binding
GO:0043130--F:ubiquitin binding
GO:0006895--P:Golgi to endosome transport
GO:0006896--P:Golgi to vacuole transport
GO:0043328--P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

KEGG

sce:YHR108W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000135	Aegilops tauschii	30.52	9.00e-16	77.00
IUUC-Aml-002171	Ailuropoda melanoleuca	30.97	3.00e-15	74.30
IUUC-Atr-003138	Amborella trichopoda	29.61	5.00e-11	60.80
IUUC-Apl-003683	Anas platyrhynchos	25.00	1.00e-14	72.80
IUUC-Aca-004859	Anolis carolinensis	25.68	1.00e-13	69.70
IUUC-Ath-007359	Arabidopsis thaliana	23.93	6.00e-16	77.00
IUUC-Ago-007767	Ashbya gossypii	56.31	4.00e-177	612.00
IUUC-Acl-008243	Aspergillus clavatus	48.00	8.00e-96	342.00
IUUC-Afl-008682	Aspergillus flavus	48.99	1.00e-100	358.00
IUUC-Afu-008869	Aspergillus fumigatus	50.26	4.00e-98	350.00
IUUC-Ani-009425	Aspergillus nidulans	46.03	8.00e-96	342.00
IUUC-Ang-009840	Aspergillus niger	49.36	9.00e-89	318.00
IUUC-Aor-010219	Aspergillus oryzae	39.21	5.00e-109	386.00
IUUC-Ate-010290	Aspergillus terreus	46.88	6.00e-93	332.00
IUUC-Ame-010868	Astyanax mexicanus	27.30	1.00e-16	79.70
IUUC-Bgr-012048	Blumeria graminis	50.90	2.00e-93	334.00
IUUC-Bta-013410	Bos taurus	25.93	8.00e-19	86.30
IUUC-Bci-013954	Botrytis cinerea	47.84	1.00e-91	328.00
IUUC-Bdi-015001	Brachypodium distachyon	36.11	4.00e-15	74.70
IUUC-Bra-017805	Brassica rapa	23.49	2.00e-16	79.00
IUUC-Cel-018158	Caenorhabditis elegans	30.59	1.00e-14	72.40
IUUC-Cfa-021024	Canis familiaris	25.50	9.00e-18	82.80
IUUC-Cpo-021418	Cavia porcellus	26.54	2.00e-19	88.60
IUUC-Csa-023653	Chlorocebus sabaeus	25.15	2.00e-17	81.60
IUUC-Cin-025211	Ciona intestinalis	26.52	7.00e-16	77.00
IUUC-Csv-026066	Ciona savignyi	27.46	1.00e-18	85.90
IUUC-Cgl-026721	Colletotrichum gloeosporioides	46.38	9.00e-96	342.00
IUUC-Cne-026931	Cryptococcus neoformans	41.30	4.00e-61	226.00
IUUC-Dre-028309	Danio rerio	27.86	2.00e-19	89.00
IUUC-Dno-029588	Dasypus novemcinctus	31.55	3.00e-16	78.20
IUUC-Dor-030638	Dipodomys ordii	26.35	2.00e-13	68.90
IUUC-Dse-031293	Dothistroma septosporum	49.42	3.00e-97	347.00
IUUC-Dme-032144	Drosophila melanogaster	29.11	3.00e-19	87.80
IUUC-Eca-034207	Equus caballus	26.02	2.00e-18	85.10
IUUC-Fca-036096	Felis catus	30.95	5.00e-16	77.00
IUUC-Fal-037437	Ficedula albicollis	25.23	3.00e-16	78.20
IUUC-Fox-037776	Fusarium oxysporum	51.33	1.00e-90	325.00
IUUC-Fso-038382	Fusarium solani	53.04	2.00e-88	318.00
IUUC-Ggr-039779	Gaeumannomyces graminis	49.49	2.00e-92	330.00
IUUC-Gga-041130	Gallus gallus	25.81	9.00e-15	73.60
IUUC-Gac-042515	Gasterosteus aculeatus	28.12	6.00e-19	87.40
IUUC-Gma-043428	Glycine max	24.85	1.00e-16	79.70
IUUC-Ggo-045180	Gorilla gorilla	30.95	4.00e-16	77.40
IUUC-Hsa-045697	Homo sapiens	30.95	4.00e-16	77.40
IUUC-Itr-049028	Ictidomys tridecemlineatus	25.98	5.00e-19	87.00
IUUC-Kpa-049359	Komagataella pastoris	43.24	2.00e-126	443.00
IUUC-Lch-049582	Latimeria chalumnae	24.22	1.00e-12	66.60
IUUC-Loc-052081	Lepisosteus oculatus	25.24	7.00e-19	86.70
IUUC-Lma-053070	Leptosphaeria maculans	50.15	5.00e-90	323.00
IUUC-Laf-053664	Loxodonta africana	23.89	1.00e-16	79.00
IUUC-Mcc-055637	Macaca mulatta	30.95	4.00e-16	77.40
IUUC-Mor-057096	Magnaporthe oryzae	52.40	8.00e-90	322.00
IUUC-Mpo-057584	Magnaporthe poae	42.75	5.00e-44	170.00
IUUC-Mtr-057784	Medicago truncatula	25.50	8.00e-17	80.10
IUUC-Mla-058817	Melampsora laricipopulina	41.48	2.00e-73	267.00
IUUC-Mga-060101	Meleagris gallopavo	26.24	5.00e-14	70.90
IUUC-Mvi-060415	Microbotryum violaceum	46.13	3.00e-69	254.00
IUUC-Mmr-060929	Microcebus murinus	30.95	5.00e-16	77.00
IUUC-Mdo-062456	Monodelphis domestica	32.74	1.00e-17	82.40
IUUC-Mmu-063746	Mus musculus	25.85	6.00e-18	83.60
IUUC-Mac-064731	Musa acuminata	24.59	6.00e-16	78.20
IUUC-Mpu-066772	Mustela putorius furo	25.77	2.00e-19	87.80
IUUC-Mlu-067475	Myotis lucifugus	24.54	2.00e-16	77.80
IUUC-Nfi-068497	Neosartorya fischeri	50.00	4.00e-97	347.00
IUUC-Ncr-068625	Neurospora crassa	49.00	9.00e-93	332.00
IUUC-Opr-070780	Ochotona princeps	30.25	3.00e-16	77.40
IUUC-Ont-071992	Oreochromis niloticus	27.46	2.00e-21	95.50
IUUC-Ocu-073922	Oryctolagus cuniculus	30.95	6.00e-16	76.60
IUUC-Oba-075564	Oryza barthii	23.99	2.00e-15	75.50
IUUC-Obr-076278	Oryza brachyantha	23.57	2.00e-15	75.50
IUUC-Ogl-077758	Oryza glaberrima	36.11	2.00e-15	75.10
IUUC-Ogu-078839	Oryza glumaepatula	23.56	5.00e-16	77.40
IUUC-Oin-079919	Oryza indica	23.99	2.00e-15	75.50
IUUC-Olo-080980	Oryza longistaminata	22.64	1.00e-14	72.80
IUUC-Oni-082876	Oryza nivara	35.19	6.00e-15	73.60
IUUC-Oru-084640	Oryza rufipogon	24.32	3.00e-15	75.10
IUUC-Osa-085855	Oryza sativa	23.99	2.00e-15	75.50
IUUC-Oga-088302	Otolemur garnettii	30.36	8.00e-16	76.30
IUUC-Oar-090246	Ovis aries	26.20	5.00e-17	80.50
IUUC-Ptr-091081	Pan troglodytes	30.95	5.00e-16	77.00
IUUC-Pan-092566	Papio anubis	30.95	4.00e-16	77.40
IUUC-Psi-093744	Pelodiscus sinensis	30.95	6.00e-16	77.00
IUUC-Pno-094904	Phaeosphaeria nodorum	53.66	1.00e-70	257.00
IUUC-Ppa-095533	Physcomitrella patens	39.19	2.00e-10	58.90
IUUC-Pfo-096335	Poecilia formosa	28.12	4.00e-22	97.80
IUUC-Pab-098769	Pongo abelii	30.97	3.00e-15	74.30
IUUC-Pop-099695	Populus trichocarpa	23.56	9.00e-16	76.60
IUUC-Pca-100907	Procavia capensis	29.94	2.00e-15	74.70
IUUC-Pva-102610	Pteropus vampyrus	24.61	2.00e-16	78.20
IUUC-Pgr-103677	Puccinia graminis	42.35	1.00e-76	278.00
IUUC-Pte-104353	Pyrenophora teres	49.12	1.00e-88	318.00
IUUC-Pyt-104704	Pyrenophora triticirepentis	48.83	6.00e-89	319.00
IUUC-Rno-105379	Rattus norvegicus	32.14	3.00e-16	77.80
IUUC-Sha-106548	Sarcophilus harrisii	25.34	4.00e-14	71.20
IUUC-Spo-108179	Schizosaccharomyces pombe	50.33	2.00e-79	288.00
IUUC-Smo-109256	Selaginella moellendorffii	40.79	4.00e-13	63.50
IUUC-Sit-110727	Setaria italica	25.57	1.00e-18	86.30
IUUC-Sly-111100	Solanum lycopersicum	29.41	3.00e-14	71.60
IUUC-Sbi-114813	Sorghum bicolor	24.58	7.00e-17	80.10
IUUC-Sre-115232	Sporisorium reilianum	40.73	1.00e-72	265.00
IUUC-Tgu-117517	Taeniopygia guttata	32.74	1.00e-17	82.40
IUUC-Tru-118023	Takifugu rubripes	26.59	2.00e-20	91.30
IUUC-Tni-120701	Tetraodon nigroviridis	23.64	4.00e-17	80.90
IUUC-Tre-121890	Trichoderma reesei	51.35	6.00e-97	345.00
IUUC-Tvi-122537	Trichoderma virens	50.15	3.00e-87	313.00
IUUC-Tae-123748	Triticum aestivum	25.25	5.00e-17	80.90
IUUC-Tur-126378	Triticum urartu	26.16	7.00e-09	53.90
IUUC-Tme-126920	Tuber melanosporum	52.23	8.00e-94	335.00
IUUC-Tbe-127589	Tupaia belangeri	24.91	9.00e-13	66.60
IUUC-Uma-129380	Ustilago maydis	41.69	2.00e-69	254.00
IUUC-Vda-129948	Verticillium dahliae	53.57	1.00e-85	308.00
IUUC-Vvi-131122	Vitis vinifera	23.33	1.00e-14	72.80
IUUC-Xtr-132922	Xenopus tropicalis	26.44	1.00e-17	82.80
IUUC-Xma-133566	Xiphophorus maculatus	28.12	2.00e-22	99.00
IUUC-Yli-134564	Yarrowia lipolytica	51.34	8.00e-92	328.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence