iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Sce-106243

Ensembl Protein ID

YBR175W

UniProt Accession

P38123; D6VQH0; SWD3_YEAST

Genbank Protein ID

CAA85136.1; AAT93231.1; DAA07290.1

Protein Name

COMPASS component SWD3; Complex proteins associated with SET1 protein SWD3; Set1C component SWD3

Genbank Nucleotide ID

Z36043; AY693212; BK006936

Gene Name

SWD3; CPS30; SAF35; YBR175W; YBR1237

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YBR175W	YBR175W	YBR175W

Annotation

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.60e-21	72.1	137	176
UBD/Beta-Prp	3.80e-41	139.6	15	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllks 38
           H++ v +++   +d  +l+sGs+Dg i+++D  tg++lk+
   Q: 137  HSEAVVSVDVpmNDsSILSSGSYDGLIRIFDAETGHCLKT 176
           9999*****99988899********************986 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvs 111
             tc k+spd+++la +     i ++d+ + ++ ++l  +h  + + +++spdg+ ++t+s+D  + +  l ++  +ht+ gh++ v sl+f+++g+ l +
   Q: 15   KATCAKISPDGQFLAITQ-GLNILIYDINRRTVSQTLvTSHARPFSELCWSPDGQCIATASDDFSVEIIHL-SYGLLHTFIGHTAPVISLTFNRKGNLLFT 113
           579*************96.889*****************************************87777555.5679************************* PP
   S: 112  Gshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl.......tgghtdsvyslsfdsngkelvsgsldgtv 204
            s d+ i++wd+ +g+ ++ t s h+++v +v v+ ++ ++l sGs+D+ +r++d +tg +l+tl       +++   ++  ++f++n ++l+  sldg v
   Q: 114  SSMDESIKIWDTLNGSLMK-TISAHSEAVVSVDVPMNDsSILSSGSYDGLIRIFDAETGHCLKTLtydkdwkRENGVVPISQVKFSENARYLLVKSLDGVV 213
           ******************9.9************999999**************************9999998777889999999***************** PP
   S: 205  klwdlqtgecvrtlnght......dnvksvrfs....pnderlvsgssDgsiriWdlrsgdllktlqlhn.ssvisvavlsfgdnvlvlgsedskvn 290
           k+wd+  g +vrt++ +          + ++f+      + +++sg + g i++W+++++ ll+ l ++  +++++v  ++  +n++++ + +++  
   Q: 214  KIWDCIGGCVVRTFQVQPlekgvlHHSCGMDFLnpedGSTPLVISGYENGDIYCWNSDTKSLLQLLDGSLyHHSSPVMSIHCFGNIMCSLALNGDCC 310
           ******99999999888766666655555555566544467888999*******************9987755555555555778887776644444 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.

Protein Sequence
(Fasta)

MFQFVTPVGT QNGLKATCAK ISPDGQFLAI TQGLNILIYD INRRTVSQTL VTSHARPFSE 60
LCWSPDGQCI ATASDDFSVE IIHLSYGLLH TFIGHTAPVI SLTFNRKGNL LFTSSMDESI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCCAGT TTGTTACTCC TGTGGGAACA CAGAATGGAT TGAAAGCTAC TTGTGCGAAA 60
ATATCTCCTG ATGGGCAGTT TCTTGCTATA ACACAAGGAC TTAACATCCT GATATACGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0158--Chromosome
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0779--Telomere
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0048188--C:Set1C/COMPASS complex
GO:0006348--P:chromatin silencing at telomere
GO:0051568--P:histone H3-K4 methylation
GO:1903341--P:regulation of meiotic DNA double-strand break formation
GO:0000723--P:telomere maintenance

KEGG

sce:YBR175W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000333	Aegilops tauschii	30.30	3.00e-25	106.00
IUUC-Aml-002143	Ailuropoda melanoleuca	35.45	2.00e-36	144.00
IUUC-Apl-003436	Anas platyrhynchos	34.47	8.00e-40	155.00
IUUC-Aca-004259	Anolis carolinensis	34.27	2.00e-40	157.00
IUUC-Aly-005723	Arabidopsis lyrata	31.56	2.00e-38	150.00
IUUC-Ath-007308	Arabidopsis thaliana	31.31	1.00e-37	147.00
IUUC-Ago-007915	Ashbya gossypii	53.31	6.00e-98	348.00
IUUC-Acl-008045	Aspergillus clavatus	32.25	7.00e-40	156.00
IUUC-Afl-008596	Aspergillus flavus	32.48	2.00e-36	144.00
IUUC-Afu-009074	Aspergillus fumigatus	33.11	8.00e-39	152.00
IUUC-Ani-009318	Aspergillus nidulans	34.98	3.00e-39	154.00
IUUC-Ang-009775	Aspergillus niger	31.61	1.00e-38	152.00
IUUC-Aor-010222	Aspergillus oryzae	32.48	2.00e-36	145.00
IUUC-Ate-010583	Aspergillus terreus	33.09	2.00e-38	151.00
IUUC-Ame-011349	Astyanax mexicanus	34.78	7.00e-40	155.00
IUUC-Bgr-011968	Blumeria graminis	32.14	2.00e-35	141.00
IUUC-Bta-013016	Bos taurus	34.47	7.00e-41	158.00
IUUC-Bci-013948	Botrytis cinerea	31.70	5.00e-32	130.00
IUUC-Bdi-014263	Brachypodium distachyon	32.68	2.00e-40	157.00
IUUC-Bol-015900	Brassica oleracea	32.36	6.00e-40	155.00
IUUC-Bra-017143	Brassica rapa	33.22	1.00e-40	157.00
IUUC-Cel-018355	Caenorhabditis elegans	33.55	3.00e-41	160.00
IUUC-Cja-019936	Callithrix jacchus	34.47	7.00e-41	158.00
IUUC-Cfa-020596	Canis familiaris	34.47	7.00e-41	158.00
IUUC-Cpo-022546	Cavia porcellus	34.65	2.00e-35	140.00
IUUC-Cre-022935	Chlamydomonas reinhardtii	36.97	9.00e-33	132.00
IUUC-Csa-023053	Chlorocebus sabaeus	34.47	7.00e-41	158.00
IUUC-Cho-024642	Choloepus hoffmanni	36.00	1.00e-34	138.00
IUUC-Cin-025495	Ciona intestinalis	34.90	1.00e-40	157.00
IUUC-Csv-025988	Ciona savignyi	34.56	2.00e-40	157.00
IUUC-Cne-027025	Cryptococcus neoformans	27.49	2.00e-27	114.00
IUUC-Dre-027521	Danio rerio	34.78	5.00e-40	155.00
IUUC-Dno-029739	Dasypus novemcinctus	34.78	5.00e-40	156.00
IUUC-Dor-031095	Dipodomys ordii	36.04	7.00e-38	149.00
IUUC-Dse-031189	Dothistroma septosporum	34.81	2.00e-39	154.00
IUUC-Dme-031613	Drosophila melanogaster	33.44	2.00e-39	154.00
IUUC-Ete-033098	Echinops telfairi	32.67	3.00e-36	143.00
IUUC-Eca-033790	Equus caballus	34.47	7.00e-41	158.00
IUUC-Eeu-034805	Erinaceus europaeus	33.77	2.00e-34	137.00
IUUC-Fca-035901	Felis catus	34.47	7.00e-41	158.00
IUUC-Fal-037413	Ficedula albicollis	34.27	2.00e-40	157.00
IUUC-Fox-037876	Fusarium oxysporum	34.57	7.00e-27	111.00
IUUC-Gmo-039131	Gadus morhua	35.33	1.00e-40	158.00
IUUC-Ggr-040071	Gaeumannomyces graminis	30.77	3.00e-23	101.00
IUUC-Gga-040789	Gallus gallus	34.27	2.00e-40	157.00
IUUC-Gac-042634	Gasterosteus aculeatus	35.00	2.00e-39	154.00
IUUC-Gma-043692	Glycine max	32.15	7.00e-37	145.00
IUUC-Ggo-044443	Gorilla gorilla	34.47	7.00e-41	158.00
IUUC-Hsa-046290	Homo sapiens	34.47	7.00e-41	158.00
IUUC-Itr-048459	Ictidomys tridecemlineatus	36.51	2.00e-33	134.00
IUUC-Kpa-049404	Komagataella pastoris	36.69	1.00e-51	194.00
IUUC-Lch-049539	Latimeria chalumnae	34.78	5.00e-40	155.00
IUUC-Lpe-051082	Leersia perrieri	33.44	5.00e-41	159.00
IUUC-Loc-051743	Lepisosteus oculatus	34.78	7.00e-40	155.00
IUUC-Lma-053188	Leptosphaeria maculans	32.72	3.00e-39	154.00
IUUC-Laf-053472	Loxodonta africana	35.67	2.00e-36	143.00
IUUC-Mcc-055603	Macaca mulatta	34.47	7.00e-41	158.00
IUUC-Meu-056440	Macropus eugenii	38.16	2.00e-32	130.00
IUUC-Mpo-057333	Magnaporthe poae	30.86	5.00e-23	100.00
IUUC-Mtr-057951	Medicago truncatula	32.83	1.00e-35	141.00
IUUC-Mla-058896	Melampsora laricipopulina	32.71	6.00e-38	149.00
IUUC-Mga-060046	Meleagris gallopavo	34.27	3.00e-40	157.00
IUUC-Mvi-060453	Microbotryum violaceum	27.95	3.00e-27	114.00
IUUC-Mmr-061436	Microcebus murinus	37.99	8.00e-34	135.00
IUUC-Mdo-062204	Monodelphis domestica	33.89	3.00e-39	153.00
IUUC-Mmu-064411	Mus musculus	35.10	3.00e-34	136.00
IUUC-Mac-065310	Musa acuminata	31.41	2.00e-37	147.00
IUUC-Mpu-066755	Mustela putorius furo	35.79	2.00e-36	144.00
IUUC-Mlu-068209	Myotis lucifugus	34.47	7.00e-41	158.00
IUUC-Nfi-068538	Neosartorya fischeri	32.24	7.00e-39	152.00
IUUC-Ncr-068651	Neurospora crassa	28.85	6.00e-28	116.00
IUUC-Nle-069383	Nomascus leucogenys	35.33	2.00e-35	140.00
IUUC-Opr-070937	Ochotona princeps	35.31	3.00e-36	143.00
IUUC-Ont-071458	Oreochromis niloticus	34.78	5.00e-40	155.00
IUUC-Oan-073597	Ornithorhynchus anatinus	34.27	3.00e-40	157.00
IUUC-Oba-075082	Oryza barthii	31.58	2.00e-34	137.00
IUUC-Obr-076318	Oryza brachyantha	31.44	3.00e-30	122.00
IUUC-Ogl-077251	Oryza glaberrima	32.37	2.00e-40	157.00
IUUC-Ogu-078882	Oryza glumaepatula	30.36	9.00e-35	139.00
IUUC-Oin-079601	Oryza indica	30.68	2.00e-36	144.00
IUUC-Olo-080976	Oryza longistaminata	34.32	3.00e-39	152.00
IUUC-Ome-081430	Oryza meridionalis	32.58	1.00e-40	157.00
IUUC-Oni-082182	Oryza nivara	29.64	2.00e-34	137.00
IUUC-Opu-083880	Oryza punctata	32.90	3.00e-41	159.00
IUUC-Osa-085706	Oryza sativa	32.37	2.00e-40	157.00
IUUC-Ola-087134	Oryzias latipes	34.45	1.00e-39	154.00
IUUC-Olu-087660	Ostreococcus lucimarinus	31.65	1.00e-20	90.10
IUUC-Oga-088826	Otolemur garnettii	36.63	5.00e-37	146.00
IUUC-Oar-089860	Ovis aries	33.89	2.00e-34	137.00
IUUC-Ptr-091513	Pan troglodytes	34.47	7.00e-41	158.00
IUUC-Pan-092046	Papio anubis	34.47	7.00e-41	158.00
IUUC-Psi-093192	Pelodiscus sinensis	34.27	2.00e-40	157.00
IUUC-Pno-094881	Phaeosphaeria nodorum	32.89	3.00e-39	154.00
IUUC-Pfo-097434	Poecilia formosa	34.45	1.00e-39	154.00
IUUC-Pab-098758	Pongo abelii	35.00	6.00e-35	139.00
IUUC-Pop-099778	Populus trichocarpa	31.72	2.00e-35	140.00
IUUC-Pva-103020	Pteropus vampyrus	34.27	3.00e-40	156.00
IUUC-Pgr-103589	Puccinia graminis	29.92	2.00e-29	121.00
IUUC-Ptt-103745	Puccinia triticina	27.09	2.00e-15	74.70
IUUC-Pte-104153	Pyrenophora teres	32.24	1.00e-39	155.00
IUUC-Pyt-104712	Pyrenophora triticirepentis	33.20	1.00e-34	137.00
IUUC-Rno-105858	Rattus norvegicus	34.47	7.00e-41	158.00
IUUC-Sha-107101	Sarcophilus harrisii	34.27	3.00e-40	157.00
IUUC-Sja-107858	Schizosaccharomyces japonicus	34.86	2.00e-33	134.00
IUUC-Sit-110688	Setaria italica	31.79	3.00e-40	156.00
IUUC-Sbi-114284	Sorghum bicolor	31.46	3.00e-39	153.00
IUUC-Ssc-115346	Sus scrofa	35.45	3.00e-41	159.00
IUUC-Tgu-117172	Taeniopygia guttata	34.27	2.00e-40	157.00
IUUC-Tru-118320	Takifugu rubripes	34.78	3.00e-40	156.00
IUUC-Tca-121051	Theobroma cacao	31.66	2.00e-37	147.00
IUUC-Tre-122237	Trichoderma reesei	29.08	3.00e-32	130.00
IUUC-Tvi-122635	Trichoderma virens	29.32	1.00e-32	131.00
IUUC-Tae-123971	Triticum aestivum	32.31	9.00e-41	158.00
IUUC-Tur-126217	Triticum urartu	29.34	1.00e-22	98.20
IUUC-Tme-127061	Tuber melanosporum	32.01	5.00e-36	142.00
IUUC-Tbe-127488	Tupaia belangeri	34.67	1.00e-34	137.00
IUUC-Ttr-129309	Tursiops truncatus	33.23	2.00e-38	150.00
IUUC-Uma-129585	Ustilago maydis	27.87	1.00e-29	121.00
IUUC-Vda-129907	Verticillium dahliae	32.26	2.00e-34	138.00
IUUC-Vpa-130384	Vicugna pacos	34.78	2.00e-35	140.00
IUUC-Xtr-131945	Xenopus tropicalis	34.78	3.00e-40	157.00
IUUC-Xma-132997	Xiphophorus maculatus	34.45	1.00e-39	154.00
IUUC-Yli-134418	Yarrowia lipolytica	30.79	4.00e-37	146.00
IUUC-Zma-135765	Zea mays	30.79	1.00e-39	154.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence