iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053761

Ensembl Protein ID

ENSLAFP00000027256.1

UniProt Accession

G3UHE8; G3UHE8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005104.3	ENSLAFT00000029210.1	ENSLAFP00000027256.1
ENSLAFG00000005104.3	ENSLAFT00000005110.3	ENSLAFP00000004277.3
ENSLAFG00000005104.3	ENSLAFT00000029697.1	ENSLAFP00000021649.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.90e-22	77.6	243	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g++++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 243  VCLLCGSGSDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 289
           8*********88.6*******************.*******7.******5 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

DWQPPFACDV DKLHFTPRIQ RLNELEAQTR VKLNFLDQIA KYWELQGSTL KIPHVERKIL 60
DLFQLNKLVA EEGGFAVVCK DRKWTKIATK MGFAPAKLFP TYFRALFQRI RSPGSMWLST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTGGCAGC CACCATTTGC ATGCGATGTT GATAAGCTTC ATTTCACCCC ACGTATCCAG 60
AGGCTGAATG AATTGGAGGT AATGTCCTCA CCTGCTGTTC TGGTCGTCTG TGTTCCGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.51	1.00e-102	368.00
IUUC-Aml-001963	Ailuropoda melanoleuca	94.58	0.00e+00	2728.00
IUUC-Atr-002595	Amborella trichopoda	32.88	7.00e-107	382.00
IUUC-Apl-003770	Anas platyrhynchos	84.90	0.00e+00	2145.00
IUUC-Aca-004867	Anolis carolinensis	80.50	0.00e+00	2379.00
IUUC-Acl-008162	Aspergillus clavatus	31.61	1.00e-113	405.00
IUUC-Afl-008625	Aspergillus flavus	30.20	2.00e-108	388.00
IUUC-Afu-008796	Aspergillus fumigatus	31.22	2.00e-113	404.00
IUUC-Ani-009139	Aspergillus nidulans	30.85	3.00e-108	387.00
IUUC-Aor-010155	Aspergillus oryzae	30.20	1.00e-108	388.00
IUUC-Ate-010453	Aspergillus terreus	30.15	6.00e-106	379.00
IUUC-Ame-010620	Astyanax mexicanus	61.36	0.00e+00	1809.00
IUUC-Bgr-012241	Blumeria graminis	29.61	2.00e-103	371.00
IUUC-Bta-012733	Bos taurus	90.72	0.00e+00	2615.00
IUUC-Bci-013992	Botrytis cinerea	34.20	3.00e-104	374.00
IUUC-Bdi-014050	Brachypodium distachyon	28.65	2.00e-105	378.00
IUUC-Bol-015336	Brassica oleracea	36.45	2.00e-14	75.90
IUUC-Cja-019050	Callithrix jacchus	94.17	0.00e+00	2749.00
IUUC-Cfa-021015	Canis familiaris	94.38	0.00e+00	2714.00
IUUC-Cpo-022340	Cavia porcellus	94.04	0.00e+00	2680.00
IUUC-Csa-023441	Chlorocebus sabaeus	94.85	0.00e+00	2725.00
IUUC-Cho-024823	Choloepus hoffmanni	95.22	0.00e+00	1580.00
IUUC-Cin-025321	Ciona intestinalis	46.84	0.00e+00	896.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	30.10	4.00e-106	380.00
IUUC-Cne-026851	Cryptococcus neoformans	29.60	2.00e-112	400.00
IUUC-Dre-027707	Danio rerio	59.70	0.00e+00	1725.00
IUUC-Dno-028978	Dasypus novemcinctus	95.33	0.00e+00	2733.00
IUUC-Dor-030854	Dipodomys ordii	85.65	0.00e+00	1902.00
IUUC-Dme-032021	Drosophila melanogaster	43.95	0.00e+00	978.00
IUUC-Ete-032760	Echinops telfairi	91.69	0.00e+00	1862.00
IUUC-Eca-034370	Equus caballus	94.78	0.00e+00	2656.00
IUUC-Eeu-035012	Erinaceus europaeus	74.77	0.00e+00	1836.00
IUUC-Fca-035494	Felis catus	95.26	0.00e+00	2725.00
IUUC-Fal-037631	Ficedula albicollis	82.09	0.00e+00	2383.00
IUUC-Fox-037694	Fusarium oxysporum	31.40	4.00e-96	347.00
IUUC-Gmo-039522	Gadus morhua	57.00	0.00e+00	1617.00
IUUC-Ggr-039929	Gaeumannomyces graminis	31.90	2.00e-100	361.00
IUUC-Gga-040802	Gallus gallus	82.65	0.00e+00	2338.00
IUUC-Gac-041563	Gasterosteus aculeatus	60.31	0.00e+00	1744.00
IUUC-Gma-042675	Glycine max	33.37	6.00e-101	363.00
IUUC-Ggo-044856	Gorilla gorilla	77.71	0.00e+00	2102.00
IUUC-Hsa-045888	Homo sapiens	92.59	0.00e+00	2727.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	94.78	0.00e+00	2694.00
IUUC-Lch-050483	Latimeria chalumnae	65.39	0.00e+00	1937.00
IUUC-Lpe-051537	Leersia perrieri	32.10	9.00e-93	335.00
IUUC-Loc-052550	Lepisosteus oculatus	69.65	0.00e+00	2005.00
IUUC-Mcc-055505	Macaca mulatta	92.72	0.00e+00	2731.00
IUUC-Mor-057198	Magnaporthe oryzae	30.00	3.00e-112	400.00
IUUC-Mpo-057317	Magnaporthe poae	33.20	3.00e-103	370.00
IUUC-Mtr-058113	Medicago truncatula	43.54	2.00e-91	331.00
IUUC-Mga-059358	Meleagris gallopavo	81.74	0.00e+00	2400.00
IUUC-Mmr-060863	Microcebus murinus	94.85	0.00e+00	2717.00
IUUC-Mdo-061957	Monodelphis domestica	88.22	0.00e+00	2597.00
IUUC-Mmu-063944	Mus musculus	92.14	0.00e+00	2627.00
IUUC-Mac-065069	Musa acuminata	35.14	5.00e-08	54.70
IUUC-Mpu-066719	Mustela putorius furo	92.48	0.00e+00	2695.00
IUUC-Mlu-068086	Myotis lucifugus	86.79	0.00e+00	2499.00
IUUC-Nle-069256	Nomascus leucogenys	92.79	0.00e+00	2736.00
IUUC-Ont-071756	Oreochromis niloticus	60.76	0.00e+00	1781.00
IUUC-Oan-073568	Ornithorhynchus anatinus	89.33	0.00e+00	2596.00
IUUC-Ocu-073961	Oryctolagus cuniculus	91.40	0.00e+00	2637.00
IUUC-Oba-075388	Oryza barthii	28.52	8.00e-73	269.00
IUUC-Obr-076296	Oryza brachyantha	40.00	2.00e-89	325.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	2.00e-16	81.60
IUUC-Ogu-079040	Oryza glumaepatula	28.65	5.00e-74	273.00
IUUC-Olo-080668	Oryza longistaminata	38.83	6.00e-16	80.90
IUUC-Ome-081764	Oryza meridionalis	30.91	9.00e-91	329.00
IUUC-Oni-083012	Oryza nivara	28.44	3.00e-73	271.00
IUUC-Opu-083164	Oryza punctata	32.27	6.00e-89	323.00
IUUC-Oru-084630	Oryza rufipogon	28.44	2.00e-73	271.00
IUUC-Osa-085487	Oryza sativa	38.83	2.00e-16	81.60
IUUC-Ola-086448	Oryzias latipes	60.21	0.00e+00	1743.00
IUUC-Oga-088501	Otolemur garnettii	91.78	0.00e+00	2378.00
IUUC-Oar-090162	Ovis aries	89.84	0.00e+00	2598.00
IUUC-Ptr-090816	Pan troglodytes	92.72	0.00e+00	2739.00
IUUC-Pan-092764	Papio anubis	94.99	0.00e+00	2728.00
IUUC-Psi-093918	Pelodiscus sinensis	82.90	0.00e+00	2236.00
IUUC-Pno-094879	Phaeosphaeria nodorum	30.78	9.00e-111	395.00
IUUC-Pfo-096672	Poecilia formosa	60.33	0.00e+00	1712.00
IUUC-Pab-097854	Pongo abelii	91.13	0.00e+00	2064.00
IUUC-Pca-100241	Procavia capensis	92.73	0.00e+00	1825.00
IUUC-Ppe-101504	Prunus persica	31.62	5.00e-101	363.00
IUUC-Pva-103035	Pteropus vampyrus	83.84	0.00e+00	2165.00
IUUC-Pte-104195	Pyrenophora teres	29.36	4.00e-110	393.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	29.84	8.00e-111	395.00
IUUC-Rno-105574	Rattus norvegicus	90.53	0.00e+00	2563.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.35	1.00e-73	271.00
IUUC-Sja-107970	Schizosaccharomyces japonicus	20.04	8.00e-35	143.00
IUUC-Spo-108283	Schizosaccharomyces pombe	20.74	3.00e-40	161.00
IUUC-Sit-110534	Setaria italica	33.33	4.00e-102	367.00
IUUC-Sly-111298	Solanum lycopersicum	42.66	1.00e-103	372.00
IUUC-Sar-113477	Sorex araneus	89.08	0.00e+00	2380.00
IUUC-Ssc-116132	Sus scrofa	92.89	0.00e+00	2316.00
IUUC-Tgu-117452	Taeniopygia guttata	82.61	0.00e+00	2383.00
IUUC-Tru-117561	Takifugu rubripes	61.80	0.00e+00	1618.00
IUUC-Tsy-119271	Tarsius syrichta	94.43	0.00e+00	2175.00
IUUC-Tni-119650	Tetraodon nigroviridis	60.24	0.00e+00	1719.00
IUUC-Tvi-122263	Trichoderma virens	33.42	4.00e-97	350.00
IUUC-Tae-125894	Triticum aestivum	32.54	2.00e-103	371.00
IUUC-Tur-126632	Triticum urartu	32.51	3.00e-101	363.00
IUUC-Tbe-127890	Tupaia belangeri	90.41	0.00e+00	1551.00
IUUC-Ttr-128546	Tursiops truncatus	88.71	0.00e+00	1903.00
IUUC-Vda-129733	Verticillium dahliae	27.67	1.00e-116	415.00
IUUC-Vpa-130432	Vicugna pacos	90.19	0.00e+00	1587.00
IUUC-Vvi-131071	Vitis vinifera	45.88	4.00e-83	303.00
IUUC-Xtr-132008	Xenopus tropicalis	70.13	0.00e+00	2048.00
IUUC-Xma-133571	Xiphophorus maculatus	60.36	0.00e+00	1746.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence