iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000017098.1	ENSAMET00000018805.1	ENSAMEP00000018074.1
ENSAMEG00000017098.1	ENSAMET00000018809.1	ENSAMEP00000018078.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-06	28.5	29	67
E3 adaptor/Cullin RING/DCX/DWD	1.40e-23	82.0	363	392

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 29   CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 67
           ********99.888***********9555......999999****6 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 363  NSKISCISWssYHkNLLASSDYEGTVILWD 392
           689******9622599************** PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

SGSRKRPLLA PLCNGLINSY EDKSNDFVCP ICFDMIEEAY MTKCGHSFCY KCIHQSLEDN 60
NRCPKCNYVV DNIDHLYPNF LVNELILKQK QRFEEKRFKL DHSVSSTNGH RWQIFQDLLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGGCAGCA GGAAGAGACC TCTGCTCGCC CCCCTGTGCA ACGGGCTCAT CAACTCCTAT 60
GAGGACAAAA GCAACGACTT CGTGTGGTGA GTTGGAAGAG CATCGCCTTC CTCTTCGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	39.97	9.00e-126	444.00
IUUC-Atr-002460	Amborella trichopoda	38.70	4.00e-124	438.00
IUUC-Apl-003796	Anas platyrhynchos	98.28	0.00e+00	1157.00
IUUC-Aca-005078	Anolis carolinensis	97.73	0.00e+00	1207.00
IUUC-Aly-006014	Arabidopsis lyrata	39.97	1.00e-129	457.00
IUUC-Ath-007636	Arabidopsis thaliana	39.88	4.00e-129	455.00
IUUC-Ame-011176	Astyanax mexicanus	74.21	6.00e-70	258.00
IUUC-Bta-012595	Bos taurus	99.84	0.00e+00	1248.00
IUUC-Bdi-014152	Brachypodium distachyon	38.95	2.00e-128	453.00
IUUC-Bol-016380	Brassica oleracea	40.31	7.00e-131	461.00
IUUC-Bra-017690	Brassica rapa	39.18	3.00e-125	442.00
IUUC-Cja-018926	Callithrix jacchus	99.68	0.00e+00	1245.00
IUUC-Cfa-021088	Canis familiaris	99.51	0.00e+00	1247.00
IUUC-Cpo-022442	Cavia porcellus	98.85	0.00e+00	1214.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.45	2.00e-33	135.00
IUUC-Csa-024119	Chlorocebus sabaeus	100.00	0.00e+00	1251.00
IUUC-Cho-024883	Choloepus hoffmanni	66.11	3.00e-104	372.00
IUUC-Cin-025375	Ciona intestinalis	54.94	0.00e+00	676.00
IUUC-Cme-027350	Cyanidioschyzon merolae	41.42	2.00e-78	286.00
IUUC-Dre-028453	Danio rerio	87.70	0.00e+00	1081.00
IUUC-Dno-029887	Dasypus novemcinctus	99.03	0.00e+00	1240.00
IUUC-Dor-031110	Dipodomys ordii	80.21	0.00e+00	919.00
IUUC-Ete-033016	Echinops telfairi	84.60	0.00e+00	1028.00
IUUC-Eca-034403	Equus caballus	99.31	0.00e+00	1160.00
IUUC-Eeu-034690	Erinaceus europaeus	84.35	0.00e+00	960.00
IUUC-Fca-036475	Felis catus	98.97	0.00e+00	1165.00
IUUC-Fal-037189	Ficedula albicollis	98.82	0.00e+00	1187.00
IUUC-Gmo-039245	Gadus morhua	86.95	0.00e+00	1060.00
IUUC-Gga-040806	Gallus gallus	98.54	0.00e+00	1235.00
IUUC-Gac-042177	Gasterosteus aculeatus	88.30	0.00e+00	1104.00
IUUC-Gma-044187	Glycine max	40.52	1.00e-126	447.00
IUUC-Ggo-044430	Gorilla gorilla	98.73	0.00e+00	937.00
IUUC-Hsa-045853	Homo sapiens	99.68	0.00e+00	1246.00
IUUC-Hvu-047750	Hordeum vulgare	38.52	1.00e-92	334.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	100.00	8.00e-144	502.00
IUUC-Lch-050420	Latimeria chalumnae	92.31	0.00e+00	1149.00
IUUC-Lpe-051219	Leersia perrieri	38.82	1.00e-124	440.00
IUUC-Loc-052728	Lepisosteus oculatus	91.56	0.00e+00	1102.00
IUUC-Laf-053775	Loxodonta africana	98.70	0.00e+00	1246.00
IUUC-Meu-056595	Macropus eugenii	77.93	2.00e-177	615.00
IUUC-Mtr-058555	Medicago truncatula	40.33	2.00e-133	469.00
IUUC-Mga-059646	Meleagris gallopavo	97.94	0.00e+00	1157.00
IUUC-Mmr-060990	Microcebus murinus	100.00	0.00e+00	1251.00
IUUC-Mdo-062287	Monodelphis domestica	99.19	0.00e+00	1245.00
IUUC-Mmu-064097	Mus musculus	99.35	0.00e+00	1245.00
IUUC-Mac-065240	Musa acuminata	41.26	4.00e-135	475.00
IUUC-Mpu-066612	Mustela putorius furo	98.97	0.00e+00	1169.00
IUUC-Mlu-067967	Myotis lucifugus	97.47	0.00e+00	1165.00
IUUC-Nle-069543	Nomascus leucogenys	99.84	0.00e+00	1250.00
IUUC-Opr-070366	Ochotona princeps	83.76	0.00e+00	720.00
IUUC-Ont-071522	Oreochromis niloticus	87.82	0.00e+00	1092.00
IUUC-Oan-073409	Ornithorhynchus anatinus	98.80	0.00e+00	1161.00
IUUC-Ocu-073756	Oryctolagus cuniculus	99.33	0.00e+00	1219.00
IUUC-Oba-075149	Oryza barthii	38.83	2.00e-126	447.00
IUUC-Obr-076563	Oryza brachyantha	39.20	1.00e-126	446.00
IUUC-Ogl-077701	Oryza glaberrima	38.83	8.00e-127	447.00
IUUC-Ogu-078383	Oryza glumaepatula	38.83	8.00e-127	447.00
IUUC-Oin-079965	Oryza indica	36.68	5.00e-113	401.00
IUUC-Olo-080639	Oryza longistaminata	38.67	1.00e-124	440.00
IUUC-Ome-081821	Oryza meridionalis	38.63	1.00e-114	407.00
IUUC-Oni-082622	Oryza nivara	38.83	8.00e-127	447.00
IUUC-Opu-083295	Oryza punctata	38.83	1.00e-126	446.00
IUUC-Oru-084661	Oryza rufipogon	38.83	8.00e-127	447.00
IUUC-Osa-085766	Oryza sativa	38.83	8.00e-127	447.00
IUUC-Ola-086727	Oryzias latipes	87.66	0.00e+00	1108.00
IUUC-Olu-087702	Ostreococcus lucimarinus	42.77	3.00e-68	251.00
IUUC-Oga-088215	Otolemur garnettii	98.06	0.00e+00	1224.00
IUUC-Oar-089880	Ovis aries	99.83	0.00e+00	1222.00
IUUC-Ptr-090597	Pan troglodytes	99.68	0.00e+00	1246.00
IUUC-Pan-091987	Papio anubis	100.00	0.00e+00	1250.00
IUUC-Psi-094033	Pelodiscus sinensis	98.29	0.00e+00	1163.00
IUUC-Pma-094587	Petromyzon marinus	70.56	0.00e+00	803.00
IUUC-Ppa-095256	Physcomitrella patens	39.67	4.00e-132	465.00
IUUC-Pfo-097388	Poecilia formosa	86.98	0.00e+00	1070.00
IUUC-Pab-098029	Pongo abelii	99.68	0.00e+00	1245.00
IUUC-Pop-099319	Populus trichocarpa	39.10	4.00e-130	458.00
IUUC-Pca-100846	Procavia capensis	90.92	0.00e+00	1133.00
IUUC-Ppe-101250	Prunus persica	38.82	2.00e-120	426.00
IUUC-Pva-102407	Pteropus vampyrus	99.68	0.00e+00	1236.00
IUUC-Rno-105312	Rattus norvegicus	99.35	0.00e+00	1244.00
IUUC-Sha-106514	Sarcophilus harrisii	98.92	0.00e+00	771.00
IUUC-Smo-109418	Selaginella moellendorffii	39.81	2.00e-129	456.00
IUUC-Sit-110248	Setaria italica	38.79	9.00e-128	451.00
IUUC-Sly-110964	Solanum lycopersicum	40.43	4.00e-131	461.00
IUUC-Stu-112882	Solanum tuberosum	40.68	3.00e-132	466.00
IUUC-Sar-113230	Sorex araneus	72.20	0.00e+00	802.00
IUUC-Sbi-113962	Sorghum bicolor	36.91	2.00e-122	433.00
IUUC-Ssc-115987	Sus scrofa	99.68	2.00e-178	618.00
IUUC-Tgu-116471	Taeniopygia guttata	98.54	0.00e+00	1235.00
IUUC-Tru-118231	Takifugu rubripes	87.60	0.00e+00	1050.00
IUUC-Tsy-119415	Tarsius syrichta	98.98	0.00e+00	1167.00
IUUC-Tni-120893	Tetraodon nigroviridis	87.77	0.00e+00	1058.00
IUUC-Tca-121703	Theobroma cacao	41.15	7.00e-129	454.00
IUUC-Tae-125440	Triticum aestivum	41.02	9.00e-134	470.00
IUUC-Tur-126557	Triticum urartu	40.66	6.00e-129	454.00
IUUC-Tbe-127253	Tupaia belangeri	70.99	0.00e+00	840.00
IUUC-Ttr-129100	Tursiops truncatus	97.63	0.00e+00	1137.00
IUUC-Vpa-130613	Vicugna pacos	92.89	0.00e+00	1093.00
IUUC-Vvi-130880	Vitis vinifera	41.00	7.00e-123	434.00
IUUC-Xtr-132033	Xenopus tropicalis	95.48	0.00e+00	1234.00
IUUC-Xma-133421	Xiphophorus maculatus	86.82	0.00e+00	1069.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence