iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069153

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01119878

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000001706.1	ENSNLET00000002604.1	ENSNLEP00000002474.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.80e-114	381.5	703	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di++lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsifYSSVDELPSLDSEFYKNLTSIKRY-DGDITDLGLTLSY--DEDVMGQLVCHELIPGGKTIPV 871
           ********************777777999********************.7899998777776..5899****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i++e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 872  TNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k++l+ekL+yAi++++gFels
   Q: 1046 SKKSVLREKLRYAISMNTGFELS 1068
           ********************985 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MFTLSQTSRA WFIDRARQAR EERLVQKERE RAAVVIQAHV RSFLCRSRLQ RDIRREIDDF 60
FKADDPESTK RSGLCIFKIA RKLLFLFRIK EDNERFEKLC RSILSSMDAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACACCCCG GGGCAAGATG GAGGTTGTGC GTCGGCTGCT GCCCCGGGTC TGGCAGAACT 60
CGGGTGTTTT GGGCTGAGAC AGTGGCAGCT GCGGCCCCGA CCCCGAGTGC GGGGACCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	36.23	4.00e-106	379.00
IUUC-Aml-002107	Ailuropoda melanoleuca	96.91	0.00e+00	2096.00
IUUC-Atr-003017	Amborella trichopoda	38.48	7.00e-110	392.00
IUUC-Apl-003328	Anas platyrhynchos	88.21	0.00e+00	1850.00
IUUC-Aly-005794	Arabidopsis lyrata	38.93	3.00e-109	390.00
IUUC-Ath-007269	Arabidopsis thaliana	39.29	1.00e-111	398.00
IUUC-Bta-013547	Bos taurus	95.60	0.00e+00	2095.00
IUUC-Bdi-014502	Brachypodium distachyon	39.15	1.00e-109	391.00
IUUC-Bol-015093	Brassica oleracea	40.00	4.00e-113	402.00
IUUC-Bra-016722	Brassica rapa	40.00	8.00e-114	405.00
IUUC-Cel-018447	Caenorhabditis elegans	37.66	0.00e+00	679.00
IUUC-Cja-019855	Callithrix jacchus	98.60	0.00e+00	2131.00
IUUC-Cfa-020066	Canis familiaris	96.50	0.00e+00	2071.00
IUUC-Cpo-021504	Cavia porcellus	95.22	0.00e+00	2084.00
IUUC-Csa-023579	Chlorocebus sabaeus	98.78	0.00e+00	2140.00
IUUC-Cho-024430	Choloepus hoffmanni	85.90	0.00e+00	1548.00
IUUC-Cin-025750	Ciona intestinalis	47.34	0.00e+00	979.00
IUUC-Csv-026016	Ciona savignyi	48.23	0.00e+00	1023.00
IUUC-Dre-028271	Danio rerio	81.40	0.00e+00	1762.00
IUUC-Dno-029054	Dasypus novemcinctus	96.07	0.00e+00	2078.00
IUUC-Dor-030938	Dipodomys ordii	87.73	0.00e+00	1863.00
IUUC-Dme-031602	Drosophila melanogaster	48.01	0.00e+00	966.00
IUUC-Ete-033041	Echinops telfairi	76.50	0.00e+00	1372.00
IUUC-Eca-034411	Equus caballus	96.72	0.00e+00	2069.00
IUUC-Eeu-035201	Erinaceus europaeus	84.70	0.00e+00	806.00
IUUC-Fca-036594	Felis catus	95.22	0.00e+00	2043.00
IUUC-Fal-037317	Ficedula albicollis	84.48	0.00e+00	1857.00
IUUC-Gmo-039412	Gadus morhua	77.56	0.00e+00	1721.00
IUUC-Gga-040149	Gallus gallus	87.94	0.00e+00	1878.00
IUUC-Gac-042088	Gasterosteus aculeatus	80.11	0.00e+00	1808.00
IUUC-Gma-043839	Glycine max	39.61	3.00e-111	396.00
IUUC-Ggo-045279	Gorilla gorilla	99.25	0.00e+00	2147.00
IUUC-Hsa-045660	Homo sapiens	99.16	0.00e+00	2146.00
IUUC-Hvu-047102	Hordeum vulgare	36.23	2.00e-106	380.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	94.14	0.00e+00	1057.00
IUUC-Lch-050664	Latimeria chalumnae	82.54	0.00e+00	1820.00
IUUC-Lpe-050755	Leersia perrieri	37.04	2.00e-98	353.00
IUUC-Loc-052791	Lepisosteus oculatus	82.68	0.00e+00	1783.00
IUUC-Laf-053902	Loxodonta africana	96.35	0.00e+00	2086.00
IUUC-Mcc-054730	Macaca mulatta	98.69	0.00e+00	2139.00
IUUC-Meu-056527	Macropus eugenii	80.04	0.00e+00	1672.00
IUUC-Mtr-057671	Medicago truncatula	39.43	1.00e-111	397.00
IUUC-Mga-059260	Meleagris gallopavo	87.69	0.00e+00	1879.00
IUUC-Mmr-060804	Microcebus murinus	94.57	0.00e+00	2011.00
IUUC-Mdo-062575	Monodelphis domestica	84.13	0.00e+00	1791.00
IUUC-Mmu-063636	Mus musculus	91.50	0.00e+00	1946.00
IUUC-Mac-064989	Musa acuminata	39.54	9.00e-108	385.00
IUUC-Mpu-066677	Mustela putorius furo	96.22	0.00e+00	1959.00
IUUC-Mlu-067952	Myotis lucifugus	95.32	0.00e+00	1992.00
IUUC-Opr-070554	Ochotona princeps	94.59	0.00e+00	1877.00
IUUC-Ont-071372	Oreochromis niloticus	81.29	0.00e+00	1790.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.21	0.00e+00	736.00
IUUC-Ocu-074183	Oryctolagus cuniculus	94.86	0.00e+00	2041.00
IUUC-Oba-075213	Oryza barthii	35.18	1.00e-106	381.00
IUUC-Obr-076320	Oryza brachyantha	35.38	1.00e-109	391.00
IUUC-Ogl-077093	Oryza glaberrima	35.32	4.00e-109	389.00
IUUC-Ogu-078947	Oryza glumaepatula	37.28	3.00e-110	393.00
IUUC-Oin-080058	Oryza indica	35.52	5.00e-109	389.00
IUUC-Olo-080742	Oryza longistaminata	35.32	1.00e-108	388.00
IUUC-Ome-081741	Oryza meridionalis	34.86	2.00e-102	367.00
IUUC-Oni-082385	Oryza nivara	37.28	3.00e-110	393.00
IUUC-Opu-083529	Oryza punctata	35.36	2.00e-109	390.00
IUUC-Oru-085128	Oryza rufipogon	33.98	1.00e-95	344.00
IUUC-Osa-085557	Oryza sativa	35.52	1.00e-108	387.00
IUUC-Ola-087337	Oryzias latipes	80.64	0.00e+00	1725.00
IUUC-Oga-088342	Otolemur garnettii	95.51	0.00e+00	1983.00
IUUC-Oar-090234	Ovis aries	95.46	0.00e+00	2069.00
IUUC-Ptr-091661	Pan troglodytes	99.34	0.00e+00	2148.00
IUUC-Pan-092728	Papio anubis	98.50	0.00e+00	2133.00
IUUC-Psi-093251	Pelodiscus sinensis	87.59	0.00e+00	1752.00
IUUC-Pma-094195	Petromyzon marinus	69.74	0.00e+00	1442.00
IUUC-Ppa-095544	Physcomitrella patens	37.87	5.00e-110	392.00
IUUC-Pfo-097472	Poecilia formosa	80.92	0.00e+00	1793.00
IUUC-Pab-098570	Pongo abelii	98.97	0.00e+00	2140.00
IUUC-Pca-100110	Procavia capensis	83.43	0.00e+00	1740.00
IUUC-Ppe-101281	Prunus persica	39.01	2.00e-107	384.00
IUUC-Pva-102887	Pteropus vampyrus	91.30	0.00e+00	1940.00
IUUC-Rno-106028	Rattus norvegicus	88.42	0.00e+00	1847.00
IUUC-Sha-107331	Sarcophilus harrisii	85.26	0.00e+00	1812.00
IUUC-Smo-109488	Selaginella moellendorffii	36.96	1.00e-105	377.00
IUUC-Sit-109811	Setaria italica	35.75	4.00e-111	396.00
IUUC-Sly-111362	Solanum lycopersicum	35.50	6.00e-102	365.00
IUUC-Sar-113287	Sorex araneus	85.71	0.00e+00	731.00
IUUC-Sbi-114433	Sorghum bicolor	35.66	5.00e-112	399.00
IUUC-Ssc-116103	Sus scrofa	96.54	0.00e+00	2058.00
IUUC-Tgu-117275	Taeniopygia guttata	87.57	0.00e+00	1866.00
IUUC-Tru-118681	Takifugu rubripes	79.79	0.00e+00	1800.00
IUUC-Tsy-118985	Tarsius syrichta	92.59	0.00e+00	1050.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.48	0.00e+00	775.00
IUUC-Tca-121770	Theobroma cacao	39.18	1.00e-111	397.00
IUUC-Tae-125466	Triticum aestivum	36.82	7.00e-109	388.00
IUUC-Tur-126086	Triticum urartu	36.18	1.00e-105	378.00
IUUC-Tbe-127461	Tupaia belangeri	91.39	0.00e+00	1897.00
IUUC-Ttr-129269	Tursiops truncatus	95.51	0.00e+00	2038.00
IUUC-Vpa-130523	Vicugna pacos	76.04	1.00e-126	447.00
IUUC-Vvi-131524	Vitis vinifera	39.04	4.00e-109	389.00
IUUC-Xtr-132146	Xenopus tropicalis	83.68	0.00e+00	1835.00
IUUC-Xma-133526	Xiphophorus maculatus	80.64	0.00e+00	1786.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence