iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089339

Ensembl Protein ID

ENSOARP00000011745.1

UniProt Accession

W5PMS0; W5PMS0_SHEEP

Genbank Protein ID

ENSOARP00000011745

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01117713

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010952.1	ENSOART00000011914.1	ENSOARP00000011745.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.40e-14	52.7	188	242

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 188  IVKARFNFKQTNEDELSVCKGDIIYVT--RVEEGGWWEG--TLNGRTGWFPSNYVREIK 242
           68999*********************7..999*******..8**************997 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MQSRMWLSPC SCPREVLGSV QSAVMNPEER VVTWLISLGV LDSPKKTICD PEEFLKSSLK 60
NGVVLCKLIN RLRPGSVEKY CLEPQTEADC TNNINDFLKG CAALQVEIFD PEDLYAGVNF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTGAAAA AGAATCCCAG TGTTATCCAG GATTTTCCCC TCATTCATTC TATTTCTACA 60
TCTTTGAGTG TGAGCTCTGT GGTTTTCAAA TCCCAGAATT GGAGTGGCTT CCACCGTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

oas:101104043

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	82.13	0.00e+00	1272.00
IUUC-Apl-003960	Anas platyrhynchos	75.39	0.00e+00	1129.00
IUUC-Aca-004988	Anolis carolinensis	70.05	0.00e+00	1034.00
IUUC-Ame-011546	Astyanax mexicanus	62.87	0.00e+00	941.00
IUUC-Bta-013527	Bos taurus	99.23	0.00e+00	1476.00
IUUC-Cja-018935	Callithrix jacchus	94.20	0.00e+00	1378.00
IUUC-Cfa-021269	Canis familiaris	94.33	0.00e+00	1395.00
IUUC-Cpo-021620	Cavia porcellus	88.48	0.00e+00	1296.00
IUUC-Csa-023415	Chlorocebus sabaeus	94.46	0.00e+00	1382.00
IUUC-Cho-024736	Choloepus hoffmanni	73.61	3.00e-60	226.00
IUUC-Cin-025535	Ciona intestinalis	42.86	3.00e-82	298.00
IUUC-Cne-026866	Cryptococcus neoformans	52.94	3.00e-12	68.20
IUUC-Dre-028580	Danio rerio	63.01	0.00e+00	960.00
IUUC-Dno-029201	Dasypus novemcinctus	89.32	0.00e+00	1393.00
IUUC-Dor-030868	Dipodomys ordii	74.74	0.00e+00	1015.00
IUUC-Dme-032219	Drosophila melanogaster	43.04	2.00e-95	344.00
IUUC-Ete-032236	Echinops telfairi	52.67	2.00e-140	492.00
IUUC-Eca-033500	Equus caballus	95.10	0.00e+00	1395.00
IUUC-Eeu-035269	Erinaceus europaeus	83.91	6.00e-168	584.00
IUUC-Fca-035683	Felis catus	93.94	0.00e+00	1367.00
IUUC-Fal-037611	Ficedula albicollis	74.87	0.00e+00	1121.00
IUUC-Gmo-038980	Gadus morhua	61.25	0.00e+00	910.00
IUUC-Gga-040940	Gallus gallus	73.62	0.00e+00	1113.00
IUUC-Gac-042203	Gasterosteus aculeatus	59.52	0.00e+00	927.00
IUUC-Ggo-044755	Gorilla gorilla	94.97	0.00e+00	1387.00
IUUC-Hsa-046210	Homo sapiens	94.72	0.00e+00	1384.00
IUUC-Hvu-047839	Hordeum vulgare	36.36	7.00e-08	50.10
IUUC-Lch-049517	Latimeria chalumnae	69.57	0.00e+00	1040.00
IUUC-Loc-052393	Lepisosteus oculatus	64.75	0.00e+00	1018.00
IUUC-Laf-054196	Loxodonta africana	90.86	0.00e+00	1356.00
IUUC-Mcc-055716	Macaca mulatta	94.46	0.00e+00	1382.00
IUUC-Meu-056285	Macropus eugenii	73.22	0.00e+00	684.00
IUUC-Mtr-058576	Medicago truncatula	45.45	5.00e-12	65.10
IUUC-Mga-060029	Meleagris gallopavo	75.26	0.00e+00	1133.00
IUUC-Mmr-060803	Microcebus murinus	93.43	0.00e+00	1372.00
IUUC-Mdo-062654	Monodelphis domestica	80.33	0.00e+00	1218.00
IUUC-Mmu-063479	Mus musculus	89.61	0.00e+00	1336.00
IUUC-Mpu-066065	Mustela putorius furo	93.56	0.00e+00	1362.00
IUUC-Mlu-068222	Myotis lucifugus	92.92	0.00e+00	1348.00
IUUC-Nle-069379	Nomascus leucogenys	94.97	0.00e+00	1388.00
IUUC-Opr-070687	Ochotona princeps	72.96	0.00e+00	805.00
IUUC-Ont-072240	Oreochromis niloticus	58.61	0.00e+00	899.00
IUUC-Oan-073067	Ornithorhynchus anatinus	81.06	0.00e+00	1227.00
IUUC-Ocu-074852	Oryctolagus cuniculus	93.43	0.00e+00	1361.00
IUUC-Ola-086663	Oryzias latipes	57.92	1.00e-170	593.00
IUUC-Oga-089048	Otolemur garnettii	87.50	0.00e+00	1180.00
IUUC-Ptr-091162	Pan troglodytes	56.40	0.00e+00	679.00
IUUC-Pan-092666	Papio anubis	92.16	0.00e+00	1330.00
IUUC-Psi-093116	Pelodiscus sinensis	75.68	0.00e+00	1162.00
IUUC-Pma-094701	Petromyzon marinus	52.67	2.00e-109	389.00
IUUC-Pfo-097394	Poecilia formosa	61.77	0.00e+00	917.00
IUUC-Pab-098567	Pongo abelii	94.97	0.00e+00	1389.00
IUUC-Pca-100997	Procavia capensis	79.77	0.00e+00	1108.00
IUUC-Pva-102500	Pteropus vampyrus	92.14	0.00e+00	1326.00
IUUC-Rno-104974	Rattus norvegicus	90.11	0.00e+00	1320.00
IUUC-Sha-106845	Sarcophilus harrisii	58.31	0.00e+00	779.00
IUUC-Sar-113420	Sorex araneus	87.89	0.00e+00	1271.00
IUUC-Ssc-115679	Sus scrofa	96.10	0.00e+00	1241.00
IUUC-Tgu-117069	Taeniopygia guttata	74.61	0.00e+00	1116.00
IUUC-Tru-118488	Takifugu rubripes	55.95	0.00e+00	810.00
IUUC-Tsy-119243	Tarsius syrichta	86.06	0.00e+00	947.00
IUUC-Tni-120584	Tetraodon nigroviridis	60.08	0.00e+00	908.00
IUUC-Tbe-127994	Tupaia belangeri	78.22	0.00e+00	1122.00
IUUC-Ttr-128839	Tursiops truncatus	95.10	0.00e+00	1371.00
IUUC-Vpa-130144	Vicugna pacos	86.91	0.00e+00	1213.00
IUUC-Xtr-132624	Xenopus tropicalis	70.43	0.00e+00	1069.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence