iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093116

Ensembl Protein ID

ENSPSIP00000012027.1

UniProt Accession

K7FVG7; K7FVG7_PELSI

Genbank Protein ID

ENSPSIP00000012027

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01035277

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000010684.1	ENSPSIT00000012085.1	ENSPSIP00000012027.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.40e-15	56.3	165	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deLt +kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 165  VVKARFNFKQTNEDELTVNKGDIIYVT--RVEEGGWWEG--TLNGKTGWFPSNYVKEIK 219
           68999*********************7..999*******..8**************997 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MNSEERIVTW LISLGVLNSP KKMIGDPEQF LKASLKDGVV LCKLINRLLP GYVEKYCLEP 60
KNEADCISNI QEFLKGCVTL KVELFDARNL YAGENFSRVL STLAAVNKAT EDQPSERPCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATTCAG AAGAGCGGAT CGTGACATGG CTTATTTCAT TAGGAGTTTT AAATTCACCC 60
AAAAAGATGA TAGGTGATCC AGAGCAGTTC CTGAAAGCTT CTCTGAAAGA TGGAGTAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

pss:102461283

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	66.09	0.00e+00	1047.00
IUUC-Apl-003960	Anas platyrhynchos	87.31	0.00e+00	1328.00
IUUC-Aca-004988	Anolis carolinensis	80.03	0.00e+00	1200.00
IUUC-Ame-011546	Astyanax mexicanus	66.07	0.00e+00	983.00
IUUC-Bta-013527	Bos taurus	75.80	0.00e+00	1160.00
IUUC-Cja-018935	Callithrix jacchus	75.16	0.00e+00	1134.00
IUUC-Cfa-021269	Canis familiaris	74.90	0.00e+00	1137.00
IUUC-Cpo-021620	Cavia porcellus	71.87	0.00e+00	1079.00
IUUC-Csa-023415	Chlorocebus sabaeus	75.42	0.00e+00	1140.00
IUUC-Cin-025535	Ciona intestinalis	43.24	1.00e-84	306.00
IUUC-Cne-026866	Cryptococcus neoformans	48.33	2.00e-12	68.20
IUUC-Dre-028580	Danio rerio	66.84	0.00e+00	1020.00
IUUC-Dno-029201	Dasypus novemcinctus	71.23	0.00e+00	1108.00
IUUC-Dor-030868	Dipodomys ordii	61.13	0.00e+00	841.00
IUUC-Dme-032219	Drosophila melanogaster	45.41	2.00e-99	357.00
IUUC-Ete-032236	Echinops telfairi	54.32	1.00e-146	513.00
IUUC-Eca-033500	Equus caballus	75.80	0.00e+00	1130.00
IUUC-Eeu-035269	Erinaceus europaeus	67.91	5.00e-135	474.00
IUUC-Fca-035683	Felis catus	73.87	0.00e+00	1110.00
IUUC-Fal-037611	Ficedula albicollis	85.88	0.00e+00	1305.00
IUUC-Gmo-038980	Gadus morhua	62.82	0.00e+00	939.00
IUUC-Gga-040940	Gallus gallus	85.62	0.00e+00	1313.00
IUUC-Gac-042203	Gasterosteus aculeatus	63.93	0.00e+00	986.00
IUUC-Ggo-044755	Gorilla gorilla	75.42	0.00e+00	1139.00
IUUC-Hsa-046210	Homo sapiens	75.16	0.00e+00	1136.00
IUUC-Lch-049517	Latimeria chalumnae	75.13	0.00e+00	1125.00
IUUC-Loc-052393	Lepisosteus oculatus	66.67	0.00e+00	1040.00
IUUC-Laf-054196	Loxodonta africana	75.23	0.00e+00	1103.00
IUUC-Mcc-055716	Macaca mulatta	75.29	0.00e+00	1138.00
IUUC-Meu-056285	Macropus eugenii	69.18	0.00e+00	630.00
IUUC-Mtr-058576	Medicago truncatula	40.00	1.00e-11	63.50
IUUC-Mga-060029	Meleagris gallopavo	86.53	0.00e+00	1336.00
IUUC-Mmr-060803	Microcebus murinus	75.68	0.00e+00	1136.00
IUUC-Mdo-062654	Monodelphis domestica	77.73	0.00e+00	1172.00
IUUC-Mmu-063479	Mus musculus	73.71	0.00e+00	1093.00
IUUC-Mpu-066065	Mustela putorius furo	74.39	0.00e+00	1100.00
IUUC-Mlu-068222	Myotis lucifugus	74.29	0.00e+00	1098.00
IUUC-Nle-069379	Nomascus leucogenys	75.42	0.00e+00	1139.00
IUUC-Opr-070687	Ochotona princeps	59.27	0.00e+00	660.00
IUUC-Ont-072240	Oreochromis niloticus	60.17	0.00e+00	945.00
IUUC-Oan-073067	Ornithorhynchus anatinus	82.58	0.00e+00	1267.00
IUUC-Ocu-074852	Oryctolagus cuniculus	74.26	0.00e+00	1109.00
IUUC-Ola-086663	Oryzias latipes	57.81	0.00e+00	666.00
IUUC-Oga-089048	Otolemur garnettii	69.79	0.00e+00	961.00
IUUC-Oar-089339	Ovis aries	75.68	0.00e+00	1158.00
IUUC-Ptr-091162	Pan troglodytes	58.44	0.00e+00	719.00
IUUC-Pan-092666	Papio anubis	73.56	0.00e+00	1093.00
IUUC-Pma-094701	Petromyzon marinus	57.49	9.00e-116	409.00
IUUC-Pfo-097394	Poecilia formosa	64.74	0.00e+00	968.00
IUUC-Pab-098567	Pongo abelii	75.42	0.00e+00	1139.00
IUUC-Pca-100997	Procavia capensis	65.08	0.00e+00	916.00
IUUC-Pva-102500	Pteropus vampyrus	73.75	0.00e+00	1080.00
IUUC-Rno-104974	Rattus norvegicus	73.84	0.00e+00	1071.00
IUUC-Sha-106845	Sarcophilus harrisii	61.92	0.00e+00	831.00
IUUC-Sly-111123	Solanum lycopersicum	37.50	2.00e-09	56.20
IUUC-Sar-113420	Sorex araneus	73.36	0.00e+00	1066.00
IUUC-Ssc-115679	Sus scrofa	75.47	0.00e+00	1000.00
IUUC-Tgu-117069	Taeniopygia guttata	85.53	0.00e+00	1306.00
IUUC-Tru-118488	Takifugu rubripes	58.42	0.00e+00	851.00
IUUC-Tsy-119243	Tarsius syrichta	67.63	0.00e+00	773.00
IUUC-Tni-120584	Tetraodon nigroviridis	62.21	0.00e+00	940.00
IUUC-Tbe-127994	Tupaia belangeri	62.16	0.00e+00	907.00
IUUC-Ttr-128839	Tursiops truncatus	73.87	0.00e+00	1093.00
IUUC-Vpa-130144	Vicugna pacos	69.37	0.00e+00	983.00
IUUC-Xtr-132624	Xenopus tropicalis	73.47	0.00e+00	1135.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence