iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118301

Ensembl Protein ID

ENSTRUP00000044413.1

UniProt Accession

H2V5C9; H2V5C9_TAKRU

Protein Name

Uncharacterized protein

Gene Name

arhgef7b; arhgef7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000017333.1	ENSTRUT00000044561.1	ENSTRUP00000044412.1
ENSTRUG00000017333.1	ENSTRUT00000044562.1	ENSTRUP00000044413.1
ENSTRUG00000017333.1	ENSTRUT00000044563.1	ENSTRUP00000044414.1
ENSTRUG00000017333.1	ENSTRUT00000044564.1	ENSTRUP00000044415.1
ENSTRUG00000017333.1	ENSTRUT00000044565.1	ENSTRUP00000044416.1
ENSTRUG00000017333.1	ENSTRUT00000044566.1	ENSTRUP00000044417.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.00e-15	55.8	114	168

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ + ++ +n+deL++ kGd++ v    ++d+gW++g    +gk+G fP+n+v++l+
   Q: 114  LVKARFAFQQTNEDELSFSKGDIIIVS--RQEDGGWWEG--SYNGKSGWFPSNYVRELK 168
           58999*******************997..999*******..9**************986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

IFQFLPEPRS DNECQRNITE FINGCGAFGV ETFEVSDLLQ GLNFSKVLNA LVALNKATEG 60
LGVPEDNVCV PPSSTLRIKS FDSLNTQTTR SSKLLQPQYR SLDMSEGNGC GNLLVKARFA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACTCCG CCGAGCAAAC CGTAACCTGG CTCATATCGC TGGGAGTCCT GGAGTCTCCA 60
AAGAAAAGCA TCTCCGACCC TGAGGCTTTC CTCCAGGCGT CTCTGCAGGA TGGAGCCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0001525--P:angiogenesis
GO:0001935--P:endothelial cell proliferation
GO:0055113--P:epiboly involved in gastrulation with mouth forming second
GO:0071896--P:protein localization to adherens junction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005591	Arabidopsis lyrata	40.38	1.00e-08	53.90
IUUC-Cre-022932	Chlamydomonas reinhardtii	40.00	3.10e-01	28.50
IUUC-Gac-041950	Gasterosteus aculeatus	76.25	0.00e+00	1132.00
IUUC-Mtr-058576	Medicago truncatula	51.92	3.00e-11	62.40
IUUC-Ont-072325	Oreochromis niloticus	81.37	0.00e+00	1241.00
IUUC-Ola-086601	Oryzias latipes	80.97	0.00e+00	1185.00
IUUC-Pfo-096932	Poecilia formosa	79.20	0.00e+00	1220.00
IUUC-Tni-120394	Tetraodon nigroviridis	91.32	0.00e+00	1279.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence