iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-049063

Ensembl Protein ID

ENSSTOP00000004308.2

UniProt Accession

I3M4W3; I3M4W3_ICTTR

Genbank Protein ID

ENSSTOP00000004308

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01098759

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004795.2	ENSSTOT00000004797.2	ENSSTOP00000004308.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.60e-16	60.0	430	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 430  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDSGQVGLYPANYVEAIQ 486
           799************************.9**********.59*************9885 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSVPYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMSCLHERAR IEKAYAQQLT 60
EWARRWKQLV EKGPQYGTVE RAWMAVMSEA ERVSELHLEV KASLMNEDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGCTGCTG CCTCACCCTT TAGAGAGATG TCTGTTCCCT ATGATGACTC CGTGGGCGTG 60
GAGGTGTCCA GTGACAGCTT CTGGGAGGTA AAGCCTGGCA CCCTGCTGGT GATGCAGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	93.83	0.00e+00	864.00
IUUC-Apl-003574	Anas platyrhynchos	86.24	0.00e+00	771.00
IUUC-Aca-004251	Anolis carolinensis	81.65	0.00e+00	743.00
IUUC-Ame-011756	Astyanax mexicanus	65.88	0.00e+00	662.00
IUUC-Bta-013193	Bos taurus	91.15	0.00e+00	813.00
IUUC-Cja-018756	Callithrix jacchus	95.47	0.00e+00	856.00
IUUC-Cfa-020545	Canis familiaris	94.24	0.00e+00	896.00
IUUC-Cpo-022000	Cavia porcellus	89.51	0.00e+00	894.00
IUUC-Csa-024030	Chlorocebus sabaeus	93.93	0.00e+00	761.00
IUUC-Cin-025707	Ciona intestinalis	43.30	4.00e-105	374.00
IUUC-Csv-026244	Ciona savignyi	42.32	4.00e-54	203.00
IUUC-Dre-028104	Danio rerio	63.21	3.00e-162	564.00
IUUC-Dno-029429	Dasypus novemcinctus	92.95	0.00e+00	791.00
IUUC-Dor-030122	Dipodomys ordii	88.48	0.00e+00	795.00
IUUC-Dme-032120	Drosophila melanogaster	43.26	3.00e-105	375.00
IUUC-Eca-033367	Equus caballus	90.95	0.00e+00	835.00
IUUC-Eeu-034821	Erinaceus europaeus	76.54	0.00e+00	667.00
IUUC-Fca-036079	Felis catus	94.02	0.00e+00	860.00
IUUC-Fal-036682	Ficedula albicollis	87.02	0.00e+00	773.00
IUUC-Gmo-039681	Gadus morhua	64.49	1.00e-155	542.00
IUUC-Gga-040717	Gallus gallus	86.81	0.00e+00	776.00
IUUC-Gac-042262	Gasterosteus aculeatus	64.34	7.00e-171	593.00
IUUC-Ggo-044841	Gorilla gorilla	95.06	0.00e+00	825.00
IUUC-Hsa-046411	Homo sapiens	94.86	0.00e+00	823.00
IUUC-Loc-051975	Lepisosteus oculatus	71.07	0.00e+00	686.00
IUUC-Laf-053839	Loxodonta africana	90.19	0.00e+00	824.00
IUUC-Mcc-055783	Macaca mulatta	94.24	0.00e+00	819.00
IUUC-Mga-060087	Meleagris gallopavo	81.28	0.00e+00	708.00
IUUC-Mvi-060548	Microbotryum violaceum	41.51	4.00e-07	50.80
IUUC-Mmr-060827	Microcebus murinus	95.06	0.00e+00	876.00
IUUC-Mmu-064109	Mus musculus	94.44	0.00e+00	869.00
IUUC-Mpu-066591	Mustela putorius furo	94.24	0.00e+00	870.00
IUUC-Mlu-067826	Myotis lucifugus	93.21	0.00e+00	860.00
IUUC-Nle-069797	Nomascus leucogenys	94.65	0.00e+00	821.00
IUUC-Oan-073076	Ornithorhynchus anatinus	85.22	2.00e-155	541.00
IUUC-Ocu-074425	Oryctolagus cuniculus	94.24	0.00e+00	845.00
IUUC-Oba-075752	Oryza barthii	27.89	3.00e-03	38.50
IUUC-Ola-087556	Oryzias latipes	65.04	2.00e-161	561.00
IUUC-Oga-089009	Otolemur garnettii	85.86	0.00e+00	786.00
IUUC-Oar-089806	Ovis aries	91.56	0.00e+00	817.00
IUUC-Ptr-091111	Pan troglodytes	94.65	0.00e+00	820.00
IUUC-Pan-091749	Papio anubis	91.70	0.00e+00	807.00
IUUC-Psi-093704	Pelodiscus sinensis	87.02	0.00e+00	790.00
IUUC-Pfo-096680	Poecilia formosa	62.77	2.00e-165	575.00
IUUC-Pab-098584	Pongo abelii	94.32	3.00e-162	563.00
IUUC-Pva-102649	Pteropus vampyrus	92.39	0.00e+00	833.00
IUUC-Rno-105431	Rattus norvegicus	94.26	0.00e+00	883.00
IUUC-Sha-106641	Sarcophilus harrisii	89.70	0.00e+00	811.00
IUUC-Sar-113461	Sorex araneus	81.69	0.00e+00	726.00
IUUC-Ssc-115349	Sus scrofa	93.40	0.00e+00	828.00
IUUC-Tgu-116876	Taeniopygia guttata	86.81	0.00e+00	775.00
IUUC-Tru-118306	Takifugu rubripes	67.13	7.00e-173	599.00
IUUC-Tsy-118901	Tarsius syrichta	85.07	1.00e-153	536.00
IUUC-Tni-120120	Tetraodon nigroviridis	67.76	3.00e-177	614.00
IUUC-Xtr-132925	Xenopus tropicalis	80.49	0.00e+00	744.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence