iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049135

Ensembl Protein ID

CAY68184

UniProt Accession

C4QY61; C4QY61_KOMPG

Genbank Protein ID

CAY68184.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

FN392319

Gene Name

PAS_chr1-4_0341

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr1-4_0341	CAY68184	CAY68184

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.80e-82	274.2	186	497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeqqDaqEflaflld 101
           G+ N+g+tC+m S++Q++++ p +r+++l+ ++ k+ +    ++++++++++ ++f+ ++ ++++k + p++ll+a +++++++ gy++qDa+Ef++flld
   Q: 186  GFINMGATCFMSSIVQTIVHNPFVRDYFLSGYHAKCTK----KMDTCITCCIDEIFKVFYgTDETKGYGPTALLTAAWRVKNSLAGYSEQDAHEFWQFLLD 282
           9*****************************99999986....589***************999************************************** PP
   S: 102  qleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeeleg 202
           +++++         +e+          + e ++++  +++ +++F gql+s+++c++c +++++ +p+ldlsl++ + ++  k +l+dcL+ ft++e+l+ 
   Q: 283  EIHKSD--------TEL----------HPELDDTSTCRCITHKTFAGQLQSTVTCEKCLHSKNTVDPMLDLSLEIAKISKD-KVTLNDCLDLFTSKEKLD- 363
           ***988........222..........2234678999***************************************98865.78***************8. PP
   S: 203  enkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke.......kkkYeLiavvvHsGslssGHYv 296
             +  c++ckk+++ +k+l ++klP++L ++LkRf  +++ +s++ki+++v fpl Ld++p+++s++ +++e         +Y+L+a+v+H Gs++ GHY+
   Q: 364  -SMTICSHCKKETTRTKQLLVRKLPPILAFQLKRF--EHSASSSTKIETHVGFPLFLDMEPYTVSETLNSNEqgraswgLMTYQLFAIVIHIGSVNTGHYI 461
           .599*******************************..66668999********************99999999**************************** PP
   S: 297  ayvknekgkWllfdDskVtevkeeevleetgstaYvlfY 335
           +++kn++g+W++fdDs++t v+++ v +   s+aY+l+Y
   Q: 462  CIIKNRDGNWFKFDDSRITLVSQDYVSK---SNAYLLYY 497
           ****************************...*******9 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MTSTVKKTLE EAKFSPPVFD SCPHLKQILT SNAKDTVYRN YGLAVNVALA LKLRNGNIPL 60
YKTSDGSKVE YKKLARLRNK AVRCRECLES LSCTYFCLQC SHVGCWKNGH ASAHTKSTGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATCTA CTGTTAAGAA AACGCTTGAA GAAGCCAAAT TTTCTCCTCC AGTTTTTGAT 60
TCGTGTCCTC ATTTGAAGCA GATTTTGACC TCCAATGCAA AGGACACCGT ATACCGTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0071819--C:DUBm complex
GO:0000124--C:SAGA complex
GO:0046695--C:SLIK (SAGA-like) complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:0051568--P:histone H3-K4 methylation
GO:0034729--P:histone H3-K79 methylation
GO:0008380--P:RNA splicing
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ppa:PAS_chr1-4_0341

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	30.53	1.00e-39	156.00
IUUC-Aml-001343	Ailuropoda melanoleuca	35.41	9.00e-69	252.00
IUUC-Atr-002653	Amborella trichopoda	31.97	2.00e-67	247.00
IUUC-Apl-003433	Anas platyrhynchos	34.32	3.00e-67	246.00
IUUC-Aca-005347	Anolis carolinensis	33.67	2.00e-66	244.00
IUUC-Aly-006565	Arabidopsis lyrata	31.54	2.00e-53	201.00
IUUC-Ath-007536	Arabidopsis thaliana	31.77	7.00e-54	202.00
IUUC-Ago-007811	Ashbya gossypii	36.02	1.00e-85	308.00
IUUC-Acl-008124	Aspergillus clavatus	39.06	2.00e-77	281.00
IUUC-Afl-008464	Aspergillus flavus	37.91	1.00e-64	237.00
IUUC-Afu-008912	Aspergillus fumigatus	34.76	3.00e-76	276.00
IUUC-Ani-009168	Aspergillus nidulans	36.77	5.00e-71	259.00
IUUC-Ang-009694	Aspergillus niger	37.91	4.00e-77	279.00
IUUC-Aor-010035	Aspergillus oryzae	40.07	6.00e-48	182.00
IUUC-Ate-010382	Aspergillus terreus	37.97	1.00e-67	248.00
IUUC-Ame-011253	Astyanax mexicanus	34.34	2.00e-61	227.00
IUUC-Bgr-012150	Blumeria graminis	31.90	4.00e-64	236.00
IUUC-Bta-013303	Bos taurus	35.62	3.00e-69	253.00
IUUC-Bci-013604	Botrytis cinerea	35.40	1.00e-69	254.00
IUUC-Bdi-014171	Brachypodium distachyon	28.85	1.00e-49	188.00
IUUC-Bol-016509	Brassica oleracea	32.31	9.00e-59	219.00
IUUC-Bra-016962	Brassica rapa	31.64	6.00e-56	209.00
IUUC-Cel-018186	Caenorhabditis elegans	32.22	7.00e-37	146.00
IUUC-Cja-019283	Callithrix jacchus	35.97	4.00e-63	233.00
IUUC-Cfa-021239	Canis familiaris	35.28	1.00e-69	254.00
IUUC-Cpo-022354	Cavia porcellus	35.62	2.00e-69	254.00
IUUC-Csa-023145	Chlorocebus sabaeus	35.84	1.00e-69	255.00
IUUC-Cho-024863	Choloepus hoffmanni	33.22	4.00e-25	107.00
IUUC-Cin-025109	Ciona intestinalis	32.19	4.00e-46	176.00
IUUC-Csv-026214	Ciona savignyi	31.83	2.00e-63	234.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	33.56	7.00e-70	255.00
IUUC-Cne-027085	Cryptococcus neoformans	30.83	2.00e-59	221.00
IUUC-Cme-027115	Cyanidioschyzon merolae	27.46	4.00e-28	118.00
IUUC-Dre-027433	Danio rerio	35.65	2.00e-70	257.00
IUUC-Dno-030095	Dasypus novemcinctus	35.65	2.00e-69	254.00
IUUC-Dse-031415	Dothistroma septosporum	33.80	6.00e-77	279.00
IUUC-Dme-032074	Drosophila melanogaster	32.11	1.00e-62	231.00
IUUC-Ete-032611	Echinops telfairi	26.48	4.00e-28	117.00
IUUC-Eca-033736	Equus caballus	35.36	2.00e-69	254.00
IUUC-Eeu-035268	Erinaceus europaeus	28.87	2.00e-30	124.00
IUUC-Fca-035861	Felis catus	35.41	4.00e-71	259.00
IUUC-Fal-037645	Ficedula albicollis	34.40	2.00e-66	244.00
IUUC-Fox-038046	Fusarium oxysporum	32.27	2.00e-67	248.00
IUUC-Fso-038321	Fusarium solani	32.60	3.00e-64	236.00
IUUC-Gmo-039598	Gadus morhua	29.32	1.00e-41	162.00
IUUC-Ggr-040044	Gaeumannomyces graminis	32.74	4.00e-67	246.00
IUUC-Gga-040624	Gallus gallus	34.03	3.00e-67	246.00
IUUC-Gac-042197	Gasterosteus aculeatus	34.73	4.00e-68	249.00
IUUC-Gma-043933	Glycine max	33.40	6.00e-65	239.00
IUUC-Ggo-044409	Gorilla gorilla	35.62	2.00e-69	254.00
IUUC-Hsa-046521	Homo sapiens	35.62	2.00e-69	254.00
IUUC-Hvu-047739	Hordeum vulgare	30.97	2.00e-47	181.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	35.84	9.00e-70	255.00
IUUC-Lch-050537	Latimeria chalumnae	35.78	5.00e-70	256.00
IUUC-Lpe-050969	Leersia perrieri	31.99	3.00e-49	187.00
IUUC-Loc-052765	Lepisosteus oculatus	31.96	1.00e-57	215.00
IUUC-Lma-053105	Leptosphaeria maculans	37.83	5.00e-83	299.00
IUUC-Laf-053571	Loxodonta africana	35.65	1.00e-69	255.00
IUUC-Mcc-055166	Macaca mulatta	35.84	1.00e-69	255.00
IUUC-Mor-057103	Magnaporthe oryzae	34.01	8.00e-69	252.00
IUUC-Mpo-057621	Magnaporthe poae	32.88	5.00e-67	246.00
IUUC-Mtr-057894	Medicago truncatula	37.18	8.00e-60	222.00
IUUC-Mla-059185	Melampsora laricipopulina	34.26	1.00e-49	188.00
IUUC-Mga-059709	Meleagris gallopavo	34.32	3.00e-67	246.00
IUUC-Mvi-060530	Microbotryum violaceum	35.25	5.00e-59	219.00
IUUC-Mmr-060988	Microcebus murinus	35.84	7.00e-70	255.00
IUUC-Mdo-063065	Monodelphis domestica	35.13	5.00e-69	253.00
IUUC-Mmu-063829	Mus musculus	35.97	1.00e-69	254.00
IUUC-Mac-065419	Musa acuminata	34.40	3.00e-54	203.00
IUUC-Mpu-066687	Mustela putorius furo	35.19	4.00e-69	253.00
IUUC-Mlu-067330	Myotis lucifugus	34.33	3.00e-69	253.00
IUUC-Nfi-068423	Neosartorya fischeri	34.94	2.00e-75	273.00
IUUC-Ncr-068809	Neurospora crassa	31.51	2.00e-65	241.00
IUUC-Nle-069859	Nomascus leucogenys	31.95	3.00e-64	238.00
IUUC-Opr-070469	Ochotona princeps	30.29	1.00e-45	174.00
IUUC-Ont-071961	Oreochromis niloticus	34.48	1.00e-65	241.00
IUUC-Oan-073565	Ornithorhynchus anatinus	32.48	3.00e-63	233.00
IUUC-Ocu-074951	Oryctolagus cuniculus	34.12	9.00e-69	252.00
IUUC-Oba-075688	Oryza barthii	32.35	3.00e-49	187.00
IUUC-Obr-076652	Oryza brachyantha	31.54	1.00e-48	184.00
IUUC-Ogl-077910	Oryza glaberrima	32.35	2.00e-49	187.00
IUUC-Ogu-078479	Oryza glumaepatula	32.35	2.00e-49	187.00
IUUC-Oin-079697	Oryza indica	32.35	9.00e-50	189.00
IUUC-Olo-080811	Oryza longistaminata	32.38	9.00e-34	135.00
IUUC-Ome-081706	Oryza meridionalis	32.35	1.00e-48	185.00
IUUC-Oni-083070	Oryza nivara	32.35	1.00e-49	189.00
IUUC-Opu-083605	Oryza punctata	30.73	2.00e-43	167.00
IUUC-Oru-084522	Oryza rufipogon	32.35	2.00e-49	187.00
IUUC-Osa-085351	Oryza sativa	32.43	4.00e-50	190.00
IUUC-Ola-086743	Oryzias latipes	38.44	1.00e-59	221.00
IUUC-Olu-087695	Ostreococcus lucimarinus	33.53	7.00e-49	185.00
IUUC-Oga-089131	Otolemur garnettii	34.65	7.00e-68	249.00
IUUC-Oar-089319	Ovis aries	35.43	3.00e-69	253.00
IUUC-Ptr-090783	Pan troglodytes	35.43	2.00e-69	254.00
IUUC-Pan-092927	Papio anubis	35.84	1.00e-69	254.00
IUUC-Psi-093670	Pelodiscus sinensis	34.32	2.00e-67	247.00
IUUC-Pma-094323	Petromyzon marinus	32.83	4.00e-58	216.00
IUUC-Pno-095141	Phaeosphaeria nodorum	34.54	3.00e-68	250.00
IUUC-Ppa-095413	Physcomitrella patens	32.09	3.00e-57	214.00
IUUC-Pfo-096462	Poecilia formosa	36.42	1.00e-70	258.00
IUUC-Pab-097612	Pongo abelii	35.84	1.00e-69	254.00
IUUC-Pop-099893	Populus trichocarpa	31.52	5.00e-60	223.00
IUUC-Pca-100329	Procavia capensis	34.12	2.00e-68	251.00
IUUC-Ppe-101583	Prunus persica	32.21	1.00e-55	208.00
IUUC-Pva-102721	Pteropus vampyrus	32.33	2.00e-62	231.00
IUUC-Pgr-103657	Puccinia graminis	28.83	1.00e-43	169.00
IUUC-Pte-104340	Pyrenophora teres	36.14	2.00e-73	267.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	37.83	7.00e-81	292.00
IUUC-Rno-105247	Rattus norvegicus	35.97	1.00e-69	254.00
IUUC-Sce-106247	Saccharomyces cerevisiae	36.04	2.00e-81	293.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	35.83	6.00e-74	268.00
IUUC-Spo-108226	Schizosaccharomyces pombe	37.56	7.00e-75	272.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	33.83	6.00e-67	246.00
IUUC-Smo-109310	Selaginella moellendorffii	33.33	1.00e-65	242.00
IUUC-Sit-109716	Setaria italica	29.28	6.00e-51	192.00
IUUC-Sly-111077	Solanum lycopersicum	32.91	5.00e-60	223.00
IUUC-Stu-112203	Solanum tuberosum	37.95	3.00e-59	220.00
IUUC-Sar-113174	Sorex araneus	32.89	1.00e-59	221.00
IUUC-Sbi-114205	Sorghum bicolor	29.24	9.00e-52	195.00
IUUC-Sre-115195	Sporisorium reilianum	34.92	4.00e-35	141.00
IUUC-Ssc-115315	Sus scrofa	33.40	6.00e-67	246.00
IUUC-Tgu-116938	Taeniopygia guttata	35.43	4.00e-69	253.00
IUUC-Tru-117622	Takifugu rubripes	34.66	4.00e-69	253.00
IUUC-Tsy-119413	Tarsius syrichta	31.03	1.00e-62	231.00
IUUC-Tni-120119	Tetraodon nigroviridis	35.48	1.00e-70	258.00
IUUC-Tca-121154	Theobroma cacao	33.62	4.00e-64	236.00
IUUC-Tre-122139	Trichoderma reesei	33.73	2.00e-63	234.00
IUUC-Tvi-122599	Trichoderma virens	32.20	2.00e-63	234.00
IUUC-Tae-125608	Triticum aestivum	29.30	8.00e-55	206.00
IUUC-Tur-126423	Triticum urartu	30.40	2.00e-34	139.00
IUUC-Tme-127115	Tuber melanosporum	37.60	1.00e-91	328.00
IUUC-Tbe-127423	Tupaia belangeri	34.63	2.00e-24	104.00
IUUC-Ttr-129006	Tursiops truncatus	34.05	6.00e-67	246.00
IUUC-Uma-129455	Ustilago maydis	36.22	6.00e-35	140.00
IUUC-Vda-129829	Verticillium dahliae	35.05	1.00e-46	177.00
IUUC-Vvi-131477	Vitis vinifera	31.04	2.00e-56	211.00
IUUC-Xtr-132444	Xenopus tropicalis	33.82	4.00e-67	246.00
IUUC-Xma-133514	Xiphophorus maculatus	35.99	3.00e-71	260.00
IUUC-Yli-134357	Yarrowia lipolytica	36.25	6.00e-79	286.00
IUUC-Zma-134945	Zea mays	32.43	4.00e-51	193.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence